Flavin Mononucleotide

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  • Identifiers

    CAS number
    146-17-8

    Molecular formula
    C17H21N4O9P

    SMILES
    CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 83.66%
    Savory 20.65%
    Bitter 19.23%
    Milky 19.16%
    Cooked 16.29%
    Clean 14.77%
    Cooling 14.6%
    Fatty 13.78%
    Grape 12.72%
    Dairy 12.6%

     

    Flavor
    Bitter 64.28%
    Odorless 63.59%
    Bland 36.12%
    Mild 29.28%
    Very mild 27.35%
    Sweet-like 24.72%
    Yeast 19.74%
    Nitrile 18.91%
    Cedarleaf 18.57%
    Heather 18.38%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -2.6

    pKa est.
    7.33 (neutral)

    Molecular weight
    456.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    3516°C

    Melting point expt.

    • 290 °C

    Flash point

    • 415.15 ˚C est.

    Solubility expt.

    • 92 mg/mL

  • Synonyms

    • flavin mononucleotide
    • 146-17-8
    • Vitamin B2 phosphate
    • Riboflavin 5'-phosphate
    • RIBOFLAVIN PHOSPHATE
    • Riboflavin 5'-monophosphate
    • Riboflavin 5'-(dihydrogen phosphate)
    • Riboflavine dihydrogen phosphate
    • Riboflavin mononucleotide
    • 7N464URE7E
    • Vitamin B2 (riboflavin-5-phosphate)
    • [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] dihydrogen phosphate
    • DTXSID8023559
    • CHEBI:17621
    • {[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acid
    • Photrexa Viscous In Dextran 20%
    • (((2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo(g)pteridin-10-yl)-2,3,4-trihydroxypentyl)oxy)phosphonic acid
    • ((2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo(g)pteridin-10-yl)-2,3,4-trihydroxypentyl) dihydrogen phosphate
    • Mononucleotide, Flavin
    • Riboflavin 5' Phosphate
    • RefChem:599273
    • Mononucleotide, Riboflavin
    • 5'-Phosphate, Riboflavin
    • Riboflavin 5' Monophosphate
    • Phosphate, Sodium Riboflavin
    • Riboflavin Phosphate, Sodium
    • 5'-Monophosphate, Riboflavin
    • DTXCID403559
    • CHEBI:24041
    • 205-664-7
    • Riboflavine phosphate
    • Flanin
    • Flavol
    • Flavine mononucleotide
    • Riboflavine 5'-phosphate
    • FMN
    • Riboflavine monophosphate
    • Riboflavine 5'-monophosphate
    • Riboflavin-5-phosphate
    • Riboflavine-5'-phosphate
    • E101a
    • 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol
    • (2R,3S,4S)-5-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen phosphate
    • BRN 0068086
    • UNII-7N464URE7E
    • 1akq
    • 1akr
    • 1akt
    • 1akw
    • 1azl
    • 1czk
    • 1czl
    • 1czr
    • 1flm
    • 1nox
    • Flavinmononucleotid
    • Riboflavin, 5'-(dihydrogenphosphate)-
    • EINECS 205-664-7
    • 1c7f
    • Riboflavin Impurity 22
    • Alloxazine mononucleotide
    • Riboflavin-5'-phosphate na
    • SCHEMBL41133
    • riboflavin-5-phosphate-sodium
    • 4-26-00-02554 (Beilstein Handbook Reference)
    • Riboflavin 5''''-Phosphate
    • GTPL5185
    • orb1707841
    • CHEMBL1201794
    • Riboflavine 5-phosphate (6CI)
    • SCHEMBL21544837
    • HY-B0964A
    • MSK2571
    • RIBOFLAVIN 5''-PHOSPHATE
    • FLAVIN MONONUCLEOTIDE [MI]
    • Riboflavin5'-(dihydrogenphosphate)
    • RIBOFLAVIN PHOSPHATE [VANDF]
    • BDBM50421345
    • EBC-27146
    • RIBOFLAVIN PHOSPHATE [WHO-DD]
    • AKOS027326698
    • DB03247
    • CS-0013780
    • NS00069356
    • C00061
    • G77462
    • EN300-6477229
    • Riboflavine phosphate (Riboflavine 5'-phosphate)
    • Q376061
    • Riboflavin 5'-(dihydrogen phosphate) (8CI,9CI)
    • BRD-K09229706-236-01-8
    • BRD-K09229706-236-02-6
    • Benzo[g]pteridine, riboflavin 5'-(dihydrogen phosphate) deriv.
    • D-ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-, 5-(dihydrogen phosphate)
    • 146-17-8

  • Applications

    Flavin Mononucleotide (CAS 146-17-8, FMN) is a redox-active cofactor for flavoproteins and is used as a biochemical reagent in enzyme assays and industrial biocatalysis; it also serves as a nutritional component in animal feed and dietary supplements; it is explored as a redox mediator in biosensors and electrochemical detection; and it is studied as an intermediate or reagent in flavin-based synthesis within pharmaceutical and fine-chemical manufacturing. Applications are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.98
    methanol 2.18
    isopropanol 0.46
    water 6.64
    ethyl acetate 0.06
    n-propanol 0.7
    acetone 0.4
    n-butanol 0.32
    acetonitrile 0.18
    DMF 7.82
    toluene 0.02
    isobutanol 0.23
    1,4-dioxane 0.4
    methyl acetate 0.17
    THF 1.36
    2-butanone 0.32
    n-pentanol 0.18
    sec-butanol 0.31
    n-hexane 0.01
    ethylene glycol 8.38
    NMP 21.61
    cyclohexane 0.03
    DMSO 26.46
    n-butyl acetate 0.1
    n-octanol 0.07
    chloroform 0.06
    n-propyl acetate 0.07
    acetic acid 6.86
    dichloromethane 0.08
    cyclohexanone 0.56
    propylene glycol 5.54
    isopropyl acetate 0.03
    DMAc 10.5
    2-ethoxyethanol 2.85
    isopentanol 0.15
    n-heptane 0.03
    ethyl formate 0.34
    1,2-dichloroethane 0.09
    n-hexanol 0.17
    2-methoxyethanol 9.99
    isobutyl acetate 0.02
    tetrachloromethane 0.04
    n-pentyl acetate 0.08
    transcutol 1.35
    n-heptanol 0.18
    ethylbenzene 0.01
    MIBK 0.06
    2-propoxyethanol 1.99
    tert-butanol 0.31
    MTBE 0.04
    2-butoxyethanol 1.17
    propionic acid 1.14
    o-xylene 0.03
    formic acid 39.32
    diethyl ether 0.08
    m-xylene 0.02
    p-xylene 0.02
    chlorobenzene 0.01
    dimethyl carbonate 0.4
    n-octane 0.01
    formamide 32.45
    cyclopentanone 1.45
    2-pentanone 0.14
    anisole 0.04
    cyclopentyl methyl ether 0.2
    gamma-butyrolactone 2.04
    1-methoxy-2-propanol 3.02
    pyridine 0.38
    3-pentanone 0.15
    furfural 2.6
    n-dodecane 0.01
    diethylene glycol 6.11
    diisopropyl ether 0.02
    tert-amyl alcohol 0.26
    acetylacetone 0.21
    n-hexadecane 0.01
    acetophenone 0.11
    methyl propionate 0.19
    isopentyl acetate 0.08
    trichloroethylene 0.11
    n-nonanol 0.09
    cyclohexanol 0.24
    benzyl alcohol 0.15
    2-ethylhexanol 0.08
    isooctanol 0.09
    dipropyl ether 0.13
    1,2-dichlorobenzene 0.01
    ethyl lactate 0.43
    propylene carbonate 0.53
    n-methylformamide 5.48
    2-pentanol 0.12
    n-pentane 0.02
    1-propoxy-2-propanol 0.92
    1-methoxy-2-propyl acetate 0.22
    2-(2-methoxypropoxy) propanol 0.79
    mesitylene 0.01
    ε-caprolactone 0.49
    p-cymene 0.02
    epichlorohydrin 0.71
    1,1,1-trichloroethane 0.02
    2-aminoethanol 6.59
    morpholine-4-carbaldehyde 6.51
    sulfolane 10.08
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.31
    n-hexyl acetate 0.06
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 1.15
    sec-butyl acetate 0.03
    tert-butyl acetate 0.05
    decalin 0.01
    glycerin 25.5
    diglyme 1.73
    acrylic acid 2.52
    isopropyl myristate 0.03
    n-butyric acid 0.51
    acetyl acetate 0.05
    di(2-ethylhexyl) phthalate 0.1
    ethyl propionate 0.07
    nitromethane 4.88
    1,2-diethoxyethane 0.11
    benzonitrile 0.06
    trioctyl phosphate 0.09
    1-bromopropane 0.04
    gamma-valerolactone 3.7
    n-decanol 0.07
    triethyl phosphate 0.15
    4-methyl-2-pentanol 0.05
    propionitrile 0.13
    vinylene carbonate 0.41
    1,1,2-trichlorotrifluoroethane 4.64
    DMS 0.1
    cumene 0.01
    2-octanol 0.07
    2-hexanone 0.11
    octyl acetate 0.06
    limonene 0.03
    1,2-dimethoxyethane 1.68
    ethyl orthosilicate 0.13
    tributyl phosphate 0.08
    diacetone alcohol 0.47
    N,N-dimethylaniline 0.07
    acrylonitrile 0.28
    aniline 0.12
    1,3-propanediol 4.23
    bromobenzene 0.01
    dibromomethane 0.05
    1,1,2,2-tetrachloroethane 0.14
    2-methyl-cyclohexyl acetate 0.1
    tetrabutyl urea 0.25
    diisobutyl methanol 0.04
    2-phenylethanol 0.16
    styrene 0.01
    dioctyl adipate 0.07
    dimethyl sulfate 1.47
    ethyl butyrate 0.11
    methyl lactate 1.55
    butyl lactate 0.36
    diethyl carbonate 0.09
    propanediol butyl ether 1.11
    triethyl orthoformate 0.16
    p-tert-butyltoluene 0.02
    methyl 4-tert-butylbenzoate 0.25
    morpholine 0.96
    tert-butylamine 0.08
    n-dodecanol 0.05
    dimethoxymethane 1.44
    ethylene carbonate 0.28
    cyrene 2.48
    2-ethoxyethyl acetate 0.15
    2-ethylhexyl acetate 0.06
    1,2,4-trichlorobenzene 0.03
    4-methylpyridine 0.14
    dibutyl ether 0.04
    2,6-dimethyl-4-heptanol 0.04
    DEF 0.56
    dimethyl isosorbide 1.33
    tetrachloroethylene 0.15
    eugenol 0.49
    triacetin 0.15
    span 80 0.57
    1,4-butanediol 1.37
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.1
    methyl formate 2.83
    2-methyl-1-butanol 0.19
    n-decane 0.01
    butyronitrile 0.09
    3,7-dimethyl-1-octanol 0.04
    1-chlorooctane 0.02
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.0
    cyclooctane 0.01
    cyclopentanol 0.74
    tetrahydropyran 0.2
    tert-amyl methyl ether 0.06
    2,5,8-trioxanonane 1.52
    1-hexene 0.03
    2-isopropoxyethanol 0.65
    2,2,2-trifluoroethanol 4.89
    methyl butyrate 0.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction