FD&C Blue No. 1

Overview IFRA Request a quote

  • Identifiers

    CAS number
    3844-45-9

    Molecular formula
    C37H34N2Na2O9S3

    SMILES
    CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=CC=CC=C5S(=O)(=O)[O-].[Na+].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 58.45%
    Cooked 22.93%
    Fruity 22.66%
    Savory 21.98%
    Roasted 19.59%
    Bitter 18.76%
    Fresh 17.6%
    Grape 17.25%
    Meaty 16.37%
    Green 16.19%

     

    Flavor
    Bitter 86.13%
    Odorless 25.79%
    Nitrile 20.23%
    Bland 18.55%
    Cedarleaf 17.72%
    Very strong 17.7%
    Oriental 17.6%
    Lovage 17.5%
    Indole 17.47%
    Taco 17.35%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    2.95 (strong acid)

    Molecular weight
    792.9 g/mol

    Melting point expt.

    • 283 °C (decomposes)

    Flash point

    • 393.04 ˚C est.

    Solubility expt.

    • In water, 30 mg/mL (3.0X10+4 mg/L)
    • In ethanol, 3 mg/mL; in ethylene glycol monomethyl ether, 20 mg/mL
    • Practically insoluble in vegetable oils; pale amber solution in concentrated sulfuric acid, changing to yellow then greenish blue on dilution
    • Soluble in ether

  • Synonyms

    • Brilliant Blue FCF
    • Brilliant Blue
    • FD&C Blue No. 1
    • Blue 1206
    • FD & C Blue no. 1
    • Fenazo Blue XI
    • Japan Blue 1
    • Merantine Blue EG
    • Cosmetic Blue Lake
    • Hexacol Brilliant Blue A
    • Brilliant Blue FCF supra
    • Japan Blue No. 1
    • Intracid Pure Blue L
    • Usacert Blue No. 1
    • FDC Blue No. 1
    • Food Blue Dye No. 1
    • Modr Kysela 9
    • Aizen Food Blue No. 2
    • Modr Brilantni FCF
    • blue no. 1
    • C.I. ACID BLUE 9, DISODIUM SALT
    • Canacert Brilliant Blue FCF
    • Modr Potravinarska 2
    • Usacert FD and C Blue No. 1
    • D&C Blue No. 1
    • 1206 Blue
    • PPQ093M8HR
    • DTXSID2020189
    • H3R47K3TBD
    • DTXCID40189
    • Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, disodium salt
    • CI Food Blue 2
    • RefChem:570234
    • VIBRACOLOR BLUE ABL9
    • brilliant blue, disodium salt
    • brilliant blue diammonium salt
    • INS NO.133
    • COVACAP BLEU W 6102
    • INS-133
    • brilliant blue FCF, diammonium salt
    • CI-(1975)NO.42900
    • E-133
    • 223-339-8
    • Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sul-fophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, Hydroxide, Inner Salt, Disodium Salt
    • Food Blue 2
    • 3844-45-9
    • Erioglaucine disodium salt
    • Food Blue No. 1
    • Dolkwal Brilliant Blue
    • Acid Sky Blue A
    • Food Blue 1
    • Blue FCF
    • MFCD00012141
    • Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt
    • CHEMBL3184128
    • CHEBI:82411
    • Benzenemethanaminium,N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, disodiumsalt
    • Acid Blue 9;FD&C Blue No. 1;E133
    • disodium;2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,5-dien-1-ylidene]methyl]benzenesulfonate
    • Sodium 2-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-(ethyl(3-sulfonatobenzyl)iminio)cyclohexa-2,5-dien-1-ylidene)methyl)benzenesulfonate
    • Modr Kysela 9 [Czech]
    • Brilliant Blue FCF (Technical Grade)
    • CCRIS 97
    • Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, sodium salt (1:2)
    • Modr Brilantni FCF [Czech]
    • Food Blue No.1
    • Modr Potravinarska 2 [Czech]
    • Brilliant blue FCF, disodium salt
    • Brilliant Blue E 133
    • EINECS 223-339-8
    • UNII-H3R47K3TBD
    • UNII-PPQ093M8HR
    • Erioglaucin A
    • HSDB 7972
    • Edible pigment carmine
    • Edible pigment fruit green
    • Edible pigment bright black
    • Edible pigment lemon yellow
    • SCHEMBL124486
    • SCHEMBL124487
    • orb1299522
    • SCHEMBL29350843
    • SCHEMBL29536371
    • MSK2422
    • SGHZXLIDFTYFHQ-UHFFFAOYSA-L
    • Tox21_300516
    • BDBM50574568
    • Brilliant Blue 0.5 mg/mL in Water
    • AKOS037643360
    • FB19007
    • NCGC00254363-01
    • Ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfophenyl)benzylidene)-2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, disodium salt
    • AS-15303
    • DA-71735
    • Dihydrogen (ethyl)(4-(4-(ethyl(3-sulphonatobenzyl)amino)-2'-sulphonatobenzhydrylidene)cyclohexa-2,5-dien-1-ylidene)(3-sulphonatobenzyl)ammonium, disodium salt
    • disodium 2-{(Z)-(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)[(4Z)-4-{ethyl[(3-sulfonatophenyl)methyl]iminio}cyclohexa-2,5-dien-1-ylidene]methyl}benzenesulfonate
    • CAS-3844-45-9
    • B0790
    • F0147
    • C19352
    • D88693
    • F046732
    • Q420093
    • Disodium 2-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-(ethyl(3-sulfonatobenzyl)iminio)cyclohexa-2,5-dien-1-ylidene)methyl)benzenesulfonate
    • Disodium 2-{(Z)-(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)[(4Z)-4-{ethyl[(3-sulfonatophenyl)methyl]iminio}cyclohexa-2,5-dien-1-ylidene]methyl}benzene-1-sulfonate
    • DISODIUM N-ETHYL-N-4-((4-(ETHYL((3-SULFOPHENYL)METHYL)AMINO)PHENYL)(2-SULFOPHENYL)METHYLENE)-2,5-CYCLOHEXADIEN-1-YLIDENE)-3-SULFOBENZENEMETHANAMINIUM
    • DISODIUM SALT OF ETHYL(4-(P-(ETHYL(M-SULFOBENZYL)AMINO)-(ALPHA)-(O-SULFOPHENYL) BENZYLIDENE)-2,5-CYCLOHEXADIEN-1-YLIDENE)(M-SULFOBENZYL) AMMONIUM HYDROXIDE INNER SALT
    • disodium;2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]iminio]cyclohexa-2,5-dien-1-ylidene]methyl]benzenesulfonate
    • N-Ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfobenzeneme- thanaminium hydroxide, inner salt, disodium salt
    • sodium 2-((E)-(4-(ethyl(3-sulfonatobenzyl)amino)phenyl)((E)-4-(ethyl(3-sulfonatobenzyl)iminio)cyclohexa-2,5-dien-1-ylidene)methyl)benzenesulfonate
    • 3844-45-9

  • Applications

    FD&C Blue No. 1, CAS 3844-45-9, is a water-soluble synthetic colorant commonly used across several industries. In food processing, it serves as a colorant for beverages, candies, and processed dairy and desserts; in cosmetics and personal care, it appears as a colorant in makeup and bath/shower products; in pharmaceuticals, it is used to color syrups, liquid medicines, and tablets; in inks, coatings, and plastics, it functions as a colorant for printing inks, surface coatings, and colored polymer materials; and in household products, it is added to detergents and cleaners as a colorant. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.58
    methanol 1.16
    isopropanol 0.29
    water 0.0
    ethyl acetate 0.9
    n-propanol 0.55
    acetone 1.68
    n-butanol 0.33
    acetonitrile 0.62
    DMF 15.18
    toluene 0.26
    isobutanol 0.23
    1,4-dioxane 1.7
    methyl acetate 1.54
    THF 4.38
    2-butanone 2.32
    n-pentanol 0.2
    sec-butanol 0.33
    n-hexane 0.0
    ethylene glycol 0.34
    NMP 18.66
    cyclohexane 0.01
    DMSO 3.96
    n-butyl acetate 0.47
    n-octanol 0.12
    chloroform 4.89
    n-propyl acetate 0.52
    acetic acid 2.31
    dichloromethane 3.49
    cyclohexanone 2.56
    propylene glycol 0.74
    isopropyl acetate 0.45
    DMAc 20.6
    2-ethoxyethanol 1.54
    isopentanol 0.17
    n-heptane 0.0
    ethyl formate 1.16
    1,2-dichloroethane 1.25
    n-hexanol 0.11
    2-methoxyethanol 3.48
    isobutyl acetate 0.19
    tetrachloromethane 0.17
    n-pentyl acetate 0.56
    transcutol 1.92
    n-heptanol 0.15
    ethylbenzene 0.07
    MIBK 0.37
    2-propoxyethanol 1.68
    tert-butanol 0.18
    MTBE 0.23
    2-butoxyethanol 1.18
    propionic acid 1.49
    o-xylene 0.14
    formic acid 1.93
    diethyl ether 0.34
    m-xylene 0.11
    p-xylene 0.09
    chlorobenzene 0.46
    dimethyl carbonate 1.89
    n-octane 0.0
    formamide 3.01
    cyclopentanone 5.64
    2-pentanone 1.11
    anisole 0.45
    cyclopentyl methyl ether 0.62
    gamma-butyrolactone 6.71
    1-methoxy-2-propanol 2.6
    pyridine 2.94
    3-pentanone 1.08
    furfural 6.69
    n-dodecane 0.0
    diethylene glycol 1.18
    diisopropyl ether 0.04
    tert-amyl alcohol 0.25
    acetylacetone 1.88
    n-hexadecane 0.0
    acetophenone 0.83
    methyl propionate 1.7
    isopentyl acetate 0.3
    trichloroethylene 5.64
    n-nonanol 0.13
    cyclohexanol 0.25
    benzyl alcohol 0.62
    2-ethylhexanol 0.07
    isooctanol 0.09
    dipropyl ether 0.2
    1,2-dichlorobenzene 0.45
    ethyl lactate 0.77
    propylene carbonate 2.27
    n-methylformamide 4.73
    2-pentanol 0.14
    n-pentane 0.01
    1-propoxy-2-propanol 1.16
    1-methoxy-2-propyl acetate 1.21
    2-(2-methoxypropoxy) propanol 1.28
    mesitylene 0.04
    ε-caprolactone 2.59
    p-cymene 0.05
    epichlorohydrin 5.28
    1,1,1-trichloroethane 0.67
    2-aminoethanol 0.72
    morpholine-4-carbaldehyde 11.02
    sulfolane 8.65
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 1.01
    n-hexyl acetate 0.48
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 1.22
    sec-butyl acetate 0.26
    tert-butyl acetate 0.39
    decalin 0.0
    glycerin 1.76
    diglyme 2.79
    acrylic acid 2.35
    isopropyl myristate 0.13
    n-butyric acid 1.29
    acetyl acetate 0.78
    di(2-ethylhexyl) phthalate 0.34
    ethyl propionate 0.54
    nitromethane 5.65
    1,2-diethoxyethane 0.55
    benzonitrile 0.58
    trioctyl phosphate 0.18
    1-bromopropane 0.33
    gamma-valerolactone 11.53
    n-decanol 0.08
    triethyl phosphate 0.3
    4-methyl-2-pentanol 0.06
    propionitrile 0.65
    vinylene carbonate 2.94
    1,1,2-trichlorotrifluoroethane 9.45
    DMS 0.97
    cumene 0.03
    2-octanol 0.08
    2-hexanone 0.57
    octyl acetate 0.25
    limonene 0.07
    1,2-dimethoxyethane 2.44
    ethyl orthosilicate 0.24
    tributyl phosphate 0.19
    diacetone alcohol 0.97
    N,N-dimethylaniline 0.31
    acrylonitrile 1.5
    aniline 0.65
    1,3-propanediol 0.87
    bromobenzene 0.37
    dibromomethane 1.15
    1,1,2,2-tetrachloroethane 4.07
    2-methyl-cyclohexyl acetate 0.31
    tetrabutyl urea 0.43
    diisobutyl methanol 0.04
    2-phenylethanol 0.42
    styrene 0.11
    dioctyl adipate 0.37
    dimethyl sulfate 4.0
    ethyl butyrate 0.46
    methyl lactate 2.64
    butyl lactate 0.88
    diethyl carbonate 0.34
    propanediol butyl ether 0.91
    triethyl orthoformate 0.43
    p-tert-butyltoluene 0.04
    methyl 4-tert-butylbenzoate 0.94
    morpholine 2.87
    tert-butylamine 0.06
    n-dodecanol 0.05
    dimethoxymethane 4.27
    ethylene carbonate 1.56
    cyrene 2.26
    2-ethoxyethyl acetate 1.42
    2-ethylhexyl acetate 0.25
    1,2,4-trichlorobenzene 0.9
    4-methylpyridine 1.89
    dibutyl ether 0.1
    2,6-dimethyl-4-heptanol 0.04
    DEF 2.86
    dimethyl isosorbide 2.05
    tetrachloroethylene 1.95
    eugenol 1.19
    triacetin 1.12
    span 80 0.93
    1,4-butanediol 0.28
    1,1-dichloroethane 0.92
    2-methyl-1-pentanol 0.13
    methyl formate 3.47
    2-methyl-1-butanol 0.24
    n-decane 0.01
    butyronitrile 0.45
    3,7-dimethyl-1-octanol 0.08
    1-chlorooctane 0.05
    1-chlorotetradecane 0.01
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.55
    tetrahydropyran 0.76
    tert-amyl methyl ether 0.24
    2,5,8-trioxanonane 1.81
    1-hexene 0.03
    2-isopropoxyethanol 0.69
    2,2,2-trifluoroethanol 1.35
    methyl butyrate 0.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction