Ethylhexyloxyglyceryl palmitate

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  • Identifiers

    CAS number
    53890-13-4

    Molecular formula
    C27H54O4

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCC(COCC(CC)CCCC)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 56.92%
    Fatty 52.36%
    Oily 49.33%
    Odorless 35.15%
    Fruity 28.24%
    Creamy 23.65%
    Milky 23.36%
    Alcoholic 22.4%
    Fresh 22.21%
    Buttery 21.6%

     

    Flavor
    Waxy 47.12%
    Oily 41.11%
    Mild 40.79%
    Fatty 39.57%
    Bland 33.68%
    Faint 27.07%
    Soapy 26.65%
    Fat 25.78%
    Odorless 24.65%
    Slightly waxy 23.89%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.8

    pKa est.
    7.47 (neutral)

    Molecular weight
    442.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    500°C

    Flash point

    • 201.46 ˚C est.

  • Synonyms

    • ethylhexyloxyglyceryl palmitate
    • EINECS 258-841-6
    • 2V72XPB2Z4
    • MEXANYL GP
    • ETHYLHEXYLOXY 1-GLYCERYL PALMITATE
    • Hexadecanoic acid, 3-[(2-ethylhexyl)oxy]-2-hydroxypropyl ester
    • HEXADECANOIC ACID, 3-((2-ETHYLHEXYL)OXY)-2-HYDROXYPROPYL ESTER
    • RefChem:596779
    • ETHYLHEXYLOXYGLYCERYL PALMITATE [INCI]
    • (+-)-ETHYLHEXYLOXY 1-GLYCERYL PALMITATE
    • ETHYLHEXYLOXY 1-GLYCERYL PALMITATE, (+-)-
    • 3-[(2-ethylhexyl)oxy]-2-hydroxypropyl palmitate
    • 53890-13-4
    • [3-(2-ethylhexoxy)-2-hydroxypropyl] hexadecanoate
    • 3-((2-Ethylhexyl)oxy)-2-hydroxypropyl palmitate
    • UNII-2V72XPB2Z4
    • SCHEMBL9341551
    • DTXSID30968669
    • FYFBAZOROQDDTN-UHFFFAOYSA-N
    • 3-[(2-ETHYLHEXYL)OXY]-2-HYDROXYPROPYL HEXADECANOATE
    • NS00013672
    • (+/-)-ETHYLHEXYLOXY 1-GLYCERYL PALMITATE
    • ETHYLHEXYLOXY 1-GLYCERYL PALMITATE, (+/-)-
    • Q27255643
    • 53890-13-4

  • Applications

    Ethylhexyloxyglyceryl palmitate (CAS 53890-13-4) is a lipophilic glyceryl ester widely used in cosmetics and personal care as an emollient and skin-conditioning agent, providing slip and a light, non-greasy feel while acting as a solvent/vehicle for active ingredients and fragrance components. It is also employed as a processing aid in cosmetic emulsions and can function as a plasticizer or conditioning additive in certain polymer or coating formulations. In household products, it may serve as an emollient or solvent component to improve texture and product compatibility. In industrial manufacturing, it can be evaluated as a lipophilic solvent or plasticizer in niche formulations, subject to local regulations. In some pharmaceutical topical formulations, it may act as an excipient to improve spreadability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.9
    methanol 21.49
    isopropanol 13.59
    water 0.21
    ethyl acetate 183.27
    n-propanol 21.85
    acetone 107.55
    n-butanol 25.27
    acetonitrile 37.56
    DMF 153.61
    toluene 63.62
    isobutanol 24.95
    1,4-dioxane 160.27
    methyl acetate 113.56
    THF 409.15
    2-butanone 145.12
    n-pentanol 25.07
    sec-butanol 30.87
    n-hexane 10.2
    ethylene glycol 2.59
    NMP 574.69
    cyclohexane 69.43
    DMSO 279.08
    n-butyl acetate 168.67
    n-octanol 55.22
    chloroform 507.7
    n-propyl acetate 201.12
    acetic acid 88.32
    dichloromethane 558.21
    cyclohexanone 508.16
    propylene glycol 6.66
    isopropyl acetate 182.59
    DMAc 435.1
    2-ethoxyethanol 76.29
    isopentanol 41.62
    n-heptane 12.83
    ethyl formate 76.1
    1,2-dichloroethane 348.4
    n-hexanol 23.31
    2-methoxyethanol 71.45
    isobutyl acetate 128.02
    tetrachloromethane 135.86
    n-pentyl acetate 368.89
    transcutol 591.02
    n-heptanol 47.45
    ethylbenzene 48.86
    MIBK 165.74
    2-propoxyethanol 72.27
    tert-butanol 39.7
    MTBE 99.52
    2-butoxyethanol 147.52
    propionic acid 69.72
    o-xylene 74.37
    formic acid 22.37
    diethyl ether 66.19
    m-xylene 54.71
    p-xylene 73.78
    chlorobenzene 127.7
    dimethyl carbonate 62.3
    n-octane 7.75
    formamide 44.94
    cyclopentanone 490.13
    2-pentanone 161.25
    anisole 102.55
    cyclopentyl methyl ether 260.2
    gamma-butyrolactone 481.94
    1-methoxy-2-propanol 84.18
    pyridine 180.88
    3-pentanone 157.85
    furfural 330.64
    n-dodecane 4.33
    diethylene glycol 30.81
    diisopropyl ether 44.32
    tert-amyl alcohol 68.9
    acetylacetone 286.17
    n-hexadecane 5.34
    acetophenone 175.52
    methyl propionate 140.24
    isopentyl acetate 182.27
    trichloroethylene 660.8
    n-nonanol 57.27
    cyclohexanol 100.54
    benzyl alcohol 58.73
    2-ethylhexanol 40.82
    isooctanol 57.9
    dipropyl ether 87.33
    1,2-dichlorobenzene 189.25
    ethyl lactate 79.22
    propylene carbonate 290.98
    n-methylformamide 58.48
    2-pentanol 27.94
    n-pentane 6.96
    1-propoxy-2-propanol 99.7
    1-methoxy-2-propyl acetate 191.88
    2-(2-methoxypropoxy) propanol 136.61
    mesitylene 47.58
    ε-caprolactone 494.42
    p-cymene 47.12
    epichlorohydrin 453.45
    1,1,1-trichloroethane 425.36
    2-aminoethanol 9.39
    morpholine-4-carbaldehyde 325.93
    sulfolane 944.89
    2,2,4-trimethylpentane 13.92
    2-methyltetrahydrofuran 316.09
    n-hexyl acetate 302.41
    isooctane 5.81
    2-(2-butoxyethoxy)ethanol 181.2
    sec-butyl acetate 168.66
    tert-butyl acetate 291.95
    decalin 26.34
    glycerin 15.91
    diglyme 501.35
    acrylic acid 55.01
    isopropyl myristate 75.44
    n-butyric acid 155.79
    acetyl acetate 160.14
    di(2-ethylhexyl) phthalate 69.34
    ethyl propionate 182.7
    nitromethane 226.47
    1,2-diethoxyethane 215.54
    benzonitrile 84.5
    trioctyl phosphate 52.4
    1-bromopropane 144.23
    gamma-valerolactone 649.39
    n-decanol 32.61
    triethyl phosphate 116.83
    4-methyl-2-pentanol 28.61
    propionitrile 41.8
    vinylene carbonate 224.29
    1,1,2-trichlorotrifluoroethane 347.21
    DMS 149.71
    cumene 39.84
    2-octanol 50.18
    2-hexanone 152.68
    octyl acetate 100.59
    limonene 84.93
    1,2-dimethoxyethane 217.87
    ethyl orthosilicate 115.49
    tributyl phosphate 76.22
    diacetone alcohol 220.53
    N,N-dimethylaniline 84.54
    acrylonitrile 51.43
    aniline 62.12
    1,3-propanediol 21.08
    bromobenzene 161.15
    dibromomethane 310.52
    1,1,2,2-tetrachloroethane 602.92
    2-methyl-cyclohexyl acetate 171.15
    tetrabutyl urea 112.41
    diisobutyl methanol 36.95
    2-phenylethanol 51.18
    styrene 55.25
    dioctyl adipate 148.54
    dimethyl sulfate 185.35
    ethyl butyrate 189.16
    methyl lactate 68.08
    butyl lactate 207.89
    diethyl carbonate 107.11
    propanediol butyl ether 113.12
    triethyl orthoformate 162.7
    p-tert-butyltoluene 42.8
    methyl 4-tert-butylbenzoate 240.71
    morpholine 208.65
    tert-butylamine 26.99
    n-dodecanol 20.95
    dimethoxymethane 108.23
    ethylene carbonate 201.41
    cyrene 161.32
    2-ethoxyethyl acetate 392.98
    2-ethylhexyl acetate 158.64
    1,2,4-trichlorobenzene 247.94
    4-methylpyridine 166.42
    dibutyl ether 124.0
    2,6-dimethyl-4-heptanol 36.95
    DEF 255.19
    dimethyl isosorbide 332.61
    tetrachloroethylene 432.22
    eugenol 163.42
    triacetin 364.33
    span 80 129.79
    1,4-butanediol 10.7
    1,1-dichloroethane 247.29
    2-methyl-1-pentanol 40.92
    methyl formate 52.11
    2-methyl-1-butanol 41.84
    n-decane 11.42
    butyronitrile 51.38
    3,7-dimethyl-1-octanol 59.68
    1-chlorooctane 65.62
    1-chlorotetradecane 16.94
    n-nonane 11.06
    undecane 6.38
    tert-butylcyclohexane 17.14
    cyclooctane 18.27
    cyclopentanol 93.22
    tetrahydropyran 246.86
    tert-amyl methyl ether 123.21
    2,5,8-trioxanonane 244.44
    1-hexene 27.37
    2-isopropoxyethanol 74.93
    2,2,2-trifluoroethanol 67.41
    methyl butyrate 251.29

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction