Ethylenediamine

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  • Identifiers

    CAS number
    107-15-3

    Molecular formula
    C2H8N2

    SMILES
    C(CN)N

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fishy 86.71%
    Cheesy 54.57%
    Ripe 46.13%
    Odorless 38.86%
    Animal 26.49%
    Pungent 16.93%
    Meaty 15.4%
    Musty 12.57%
    Savory 12.37%
    Oily 12.25%

     

    Flavor
    Fishy 51.12%
    Ammoniacal 45.11%
    Meaty 29.74%
    Sulfurous 25.88%
    Sulfury 25.4%
    Ammonia 24.99%
    Odorless 22.32%
    Egg 21.02%
    Rotten 19.24%
    Glue 19.14%

     

    Odor impact est.
    High

    Odor threshold

    • Odor Threshold Low: 1.0 [mmHg]. Odor Threshold High: 11.0 [mmHg]. Odor threshold from CHEMINFO
    • Water odor threshold: 16000 mg/l @ pKa of 10.0. Air odor threshold: 1.0 ppm. Odor Safety Class: C. C= Odor safety factor from 1-26. Less than 50% of distracted persons perceive warning of TLV.
    • Odor recognition in air= 3.40 ppm (purity not specified)
    • Odor low= 2.50 mg/cu m; Odor high= 28.0 mg/cu m

  • Properties

    XLogP3-AA
    -2.0

    pKa est.
    6.19 (neutral)

    Molecular weight
    60.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • 46 °F (EPA, 1998)
    • 8.5 °C
    • 11 °C
    • 47 °F

    Boiling point

    • 241 °F at 760 mmHg (EPA, 1998)
    • 116-117 °C
    • 117.00 to 118.00 °C. @ 760.00 mm Hg
    • 117 °C
    • 241 °F

    Flash point

    • 37.08 ˚C est.
    • 93 °F (EPA, 1998)
    • 93 °F
    • 104 °F (40 °C) CLOSED CUP, 150 °F (66 °C) OPEN CUP /ANHYDROUS 76%/
    • 110 °F (closed cup)
    • 33.9 °C (open cup), 43.3 °C (closed cup)
    • 34 °C c.c.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 63 °F (NTP, 1992)
    • Crystals; sublimes without melting; freely sol in water; practically insol in alc /Dihydrochloride/
    • Sol in benzene unless insufficiently dried; slightly sol in ether
    • SOL IN ALL PROPORTIONS IN ETHYL ALCOHOL; VERY SOL IN WATER
    • Water solubility = 1X10+6 mg/l
    • Miscible with water, oxygenated and aromatic solvents
    • 1000 mg/mL
    • Solubility in water: miscible
    • Miscible

  • Synonyms

    • ethylenediamine
    • Ethane-1,2-diamine
    • 107-15-3
    • 1,2-Ethanediamine
    • 1,2-Diaminoethane
    • Ethylene diamine
    • Ethylendiamine
    • edamine
    • Dimethylenediamine
    • 1,2-Ethylenediamine
    • Aethaldiamin
    • Aethylenediamin
    • Ethyleendiamine
    • Ethylene-diamine
    • beta-Aminoethylamine
    • 1,2-Diaminoaethan
    • Algicode 106L
    • Amerstat 274
    • 1,2-Diamino-ethaan
    • 1,2-Diamino-ethano
    • Caswell No. 437
    • Ethylenediamine [JAN]
    • NCI-C60402
    • CCRIS 5224
    • HSDB 535
    • ETHYLENEDIAMINE ANHYDROUS
    • CHEBI:30347
    • 1,4-diazabutane
    • EINECS 203-468-6
    • UNII-60V9STC53F
    • Edamine [INN]
    • EPA Pesticide Chemical Code 004205
    • BRN 0605263
    • 60V9STC53F
    • DTXSID5021881
    • AI3-24231
    • CHEMBL816
    • H2NCH2CH2NH2
    • ETHANE,1,2-DIAMINO
    • DTXCID501881
    • EC 203-468-6
    • 4-04-00-01166 (Beilstein Handbook Reference)
    • 2-Aminoethylammonium chloride
    • MFCD00008204
    • EN
    • NCGC00091527-01
    • ethane, 1,2-diamino-
    • ETHYLENEDIAMINE (II)
    • ETHYLENEDIAMINE [II]
    • 1,2-diaminoethane phase II
    • ETHYLENEDIAMINE (MART.)
    • ETHYLENEDIAMINE [MART.]
    • 1,2-diaminoethane phase I beta
    • Aethaldiamin [German]
    • 1,2-diaminoethane phase I alpha
    • ethyl diamine
    • Ethyleendiamine [Dutch]
    • Aethylenediamin [German]
    • Ethylenediamine; Ethane-1,2-diamine
    • ETHYLENEDIAMINE (EP MONOGRAPH)
    • ETHYLENEDIAMINE [EP MONOGRAPH]
    • Ethylene-diamine [French]
    • Ethane-1,2-diammonium bromide
    • ETHYLENEDIAMINE (USP MONOGRAPH)
    • ETHYLENEDIAMINE [USP MONOGRAPH]
    • CAS-107-15-3
    • Ethylenediamine, ReagentPlus(R), >=99%
    • 1,2-Diaminoaethan [German]
    • 1,2-Diamino-ethaan [Dutch]
    • 1,2-Diamino-ethano [Italian]
    • Aminophylline Injection
    • UN1604
    • Ethylenediamine (anhydrous)
    • TIZANIDINE HYDROCHLORIDE IMPURITY H (EP IMPURITY)
    • TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
    • Ethylenediamine [USP:JAN]
    • Edamina
    • ethylenediarnine
    • 2-aminoethylamine
    • ethylene di amine
    • 1,2-diaminoethan
    • ethylene - diamine
    • EDN
    • 1,2-ethylendiamine
    • 1,2-diamino-ethane
    • ethane 1,2-diamine
    • Caswell No 437
    • N,N'-ethylenediamine
    • Ethylenediamine, 8CI
    • 1,2-ethylene diamine
    • 1,2-ethylene-diamine
    • Ethylenediamine [UN1604] [Corrosive]
    • .beta.-Aminoethylamine
    • ethane-1, 2-diamine
    • N,N'-ethylene diamine
    • Ethylenediamine, BioXtra
    • 1,2-Diaminoethane;EDA
    • ETHYLENEDIAMINE MOD
    • Epitope ID:117724
    • Pesticide Code 004205
    • ETHYLENEDIAMINE [MI]
    • Ethylenediamine (USP/JP15)
    • Ethylenediamine (USP/JP17)
    • ETHYLENEDIAMINE [HSDB]
    • BDBM7972
    • NH2(CH2)2NH2
    • ALPHA,OMEGA-ETHANEDIAMINE
    • ETHYLENEDIAMINE [WHO-DD]
    • 624-59-9 (di-hydrobromide)
    • 333-18-6 (di-hydrochloride)
    • 5700-49-2 (di-hydriodide)
    • Ethylenediamine, analytical standard
    • STR00309
    • Tox21_111145
    • Tox21_201202
    • STL264241
    • AKOS000118850
    • DB14189
    • FE04155
    • PB05721
    • UN 1604
    • Ethylenediamine, for synthesis, 99.0%
    • NCGC00091527-02
    • NCGC00258754-01
    • BP-20367
    • Ethylenediamine [UN1604] [Corrosive]
    • PB-05721
    • E0077

  • Applications

    Ethylenediamine is a versatile chemical intermediate used across several industries. It serves as a building block for polyamines and polyamide polymers (nylon-type resins) and acts as a chain extender or curing agent in epoxy and polyurethane systems, contributing to coatings, adhesives, and sealants. It is a precursor for chelating agents such as EDTA, enabling metal sequestration in cleaners, water treatment, and textile processing. It is also used in the manufacture of surfactants, corrosion inhibitors, and specialty chemicals, where amine functionality is required. In addition, it is employed to prepare pharmaceutical and agrochemical intermediates, and may be evaluated for use in coatings and ink formulations in electronics under appropriate regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 58.23
    methanol 204.43
    isopropanol 14.81
    water 497.47
    ethyl acetate 4.35
    n-propanol 36.46
    acetone 6.63
    n-butanol 22.07
    acetonitrile 9.83
    DMF 38.87
    toluene 0.69
    isobutanol 14.81
    1,4-dioxane 7.02
    methyl acetate 7.18
    THF 19.93
    2-butanone 6.3
    n-pentanol 8.64
    sec-butanol 11.91
    n-hexane 0.38
    ethylene glycol 134.89
    NMP 82.89
    cyclohexane 0.65
    DMSO 67.6
    n-butyl acetate 6.38
    n-octanol 2.22
    chloroform 9.45
    n-propyl acetate 3.08
    acetic acid 270.84
    dichloromethane 7.25
    cyclohexanone 11.66
    propylene glycol 81.4
    isopropyl acetate 1.62
    DMAc 26.91
    2-ethoxyethanol 27.31
    isopentanol 7.98
    n-heptane 0.91
    ethyl formate 22.3
    1,2-dichloroethane 3.63
    n-hexanol 9.77
    2-methoxyethanol 88.11
    isobutyl acetate 1.37
    tetrachloromethane 4.33
    n-pentyl acetate 3.14
    transcutol 17.52
    n-heptanol 6.0
    ethylbenzene 0.33
    MIBK 1.03
    2-propoxyethanol 29.1
    tert-butanol 6.94
    MTBE 1.3
    2-butoxyethanol 20.3
    propionic acid 84.33
    o-xylene 0.6
    formic acid 626.72
    diethyl ether 1.99
    m-xylene 0.45
    p-xylene 0.56
    chlorobenzene 2.18
    dimethyl carbonate 3.14
    n-octane 0.27
    formamide 301.93
    cyclopentanone 24.26
    2-pentanone 3.45
    anisole 1.01
    cyclopentyl methyl ether 4.81
    gamma-butyrolactone 54.28
    1-methoxy-2-propanol 27.52
    pyridine 10.81
    3-pentanone 2.81
    furfural 63.23
    n-dodecane 0.12
    diethylene glycol 51.26
    diisopropyl ether 0.34
    tert-amyl alcohol 7.23
    acetylacetone 3.05
    n-hexadecane 0.12
    acetophenone 1.98
    methyl propionate 6.0
    isopentyl acetate 3.14
    trichloroethylene 8.89
    n-nonanol 1.94
    cyclohexanol 10.51
    benzyl alcohol 4.8
    2-ethylhexanol 3.89
    isooctanol 3.27
    dipropyl ether 2.56
    1,2-dichlorobenzene 2.11
    ethyl lactate 6.41
    propylene carbonate 20.02
    n-methylformamide 102.25
    2-pentanol 5.39
    n-pentane 0.53
    1-propoxy-2-propanol 15.32
    1-methoxy-2-propyl acetate 4.41
    2-(2-methoxypropoxy) propanol 5.56
    mesitylene 0.27
    ε-caprolactone 15.47
    p-cymene 0.82
    epichlorohydrin 18.32
    1,1,1-trichloroethane 2.19
    2-aminoethanol 139.5
    morpholine-4-carbaldehyde 40.49
    sulfolane 78.47
    2,2,4-trimethylpentane 0.23
    2-methyltetrahydrofuran 8.68
    n-hexyl acetate 2.24
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 9.87
    sec-butyl acetate 1.12
    tert-butyl acetate 1.08
    decalin 0.19
    glycerin 152.3
    diglyme 13.62
    acrylic acid 120.7
    isopropyl myristate 0.62
    n-butyric acid 61.86
    acetyl acetate 3.5
    di(2-ethylhexyl) phthalate 2.3
    ethyl propionate 2.29
    nitromethane 92.97
    1,2-diethoxyethane 2.34
    benzonitrile 4.19
    trioctyl phosphate 1.87
    1-bromopropane 1.79
    gamma-valerolactone 39.34
    n-decanol 1.29
    triethyl phosphate 2.61
    4-methyl-2-pentanol 1.6
    propionitrile 8.17
    vinylene carbonate 22.06
    1,1,2-trichlorotrifluoroethane 67.98
    DMS 2.51
    cumene 0.33
    2-octanol 1.88
    2-hexanone 1.95
    octyl acetate 1.27
    limonene 1.22
    1,2-dimethoxyethane 9.85
    ethyl orthosilicate 2.36
    tributyl phosphate 2.19
    diacetone alcohol 4.43
    N,N-dimethylaniline 1.09
    acrylonitrile 16.15
    aniline 6.34
    1,3-propanediol 100.41
    bromobenzene 1.21
    dibromomethane 4.32
    1,1,2,2-tetrachloroethane 6.94
    2-methyl-cyclohexyl acetate 2.57
    tetrabutyl urea 2.59
    diisobutyl methanol 1.18
    2-phenylethanol 4.72
    styrene 0.5
    dioctyl adipate 1.42
    dimethyl sulfate 8.77
    ethyl butyrate 3.85
    methyl lactate 16.5
    butyl lactate 8.34
    diethyl carbonate 2.46
    propanediol butyl ether 16.64
    triethyl orthoformate 3.26
    p-tert-butyltoluene 0.71
    methyl 4-tert-butylbenzoate 3.28
    morpholine 17.36
    tert-butylamine 3.2
    n-dodecanol 0.9
    dimethoxymethane 6.92
    ethylene carbonate 14.29
    cyrene 12.25
    2-ethoxyethyl acetate 3.8
    2-ethylhexyl acetate 2.62
    1,2,4-trichlorobenzene 2.74
    4-methylpyridine 5.76
    dibutyl ether 0.96
    2,6-dimethyl-4-heptanol 1.18
    DEF 9.55
    dimethyl isosorbide 10.12
    tetrachloroethylene 11.29
    eugenol 6.55
    triacetin 3.15
    span 80 9.89
    1,4-butanediol 34.26
    1,1-dichloroethane 2.14
    2-methyl-1-pentanol 4.13
    methyl formate 48.2
    2-methyl-1-butanol 11.2
    n-decane 0.2
    butyronitrile 7.71
    3,7-dimethyl-1-octanol 1.3
    1-chlorooctane 0.52
    1-chlorotetradecane 0.21
    n-nonane 0.2
    undecane 0.15
    tert-butylcyclohexane 0.17
    cyclooctane 0.24
    cyclopentanol 23.41
    tetrahydropyran 5.17
    tert-amyl methyl ether 1.29
    2,5,8-trioxanonane 8.84
    1-hexene 0.88
    2-isopropoxyethanol 8.32
    2,2,2-trifluoroethanol 121.77
    methyl butyrate 4.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction