Ethylene glycol dibutyl ether

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  • Identifiers

    CAS number
    112-48-1

    Molecular formula
    C10H22O2

    SMILES
    CCCCOCCOCCCC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Ethereal 72.99%
    Alcoholic 64.19%
    Fruity 64.05%
    Fermented 54.52%
    Sweet 53.72%
    Green 52.8%
    Cognac 46.8%
    Oily 40.89%
    Winey 36.81%
    Solvent 35.64%

     

    Flavor
    Sweet 62.01%
    Fruity 41.3%
    Green 38.67%
    Earthy 34.32%
    Oil 33.41%
    Fruit 33.05%
    Alcoholic 32.98%
    Fusel 31.4%
    Vegetable 30.8%
    Wine 28.13%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    6.92 (neutral)

    Molecular weight
    174.28 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Melting point expt.

    • -69.1 °C
    • -69 °C

    Boiling point

    • 399 °F at 760 mmHg (USCG, 1999)
    • 203.3 °C
    • 203 °C

    Flash point

    • 77.55 ˚C est.
    • 185 °F (USCG, 1999)
    • 185 °F (open cup)
    • 185 °F (85 °C) (CLOSED CUP)
    • 85 °C o.c.

    Solubility expt.

    • In water, 2.0X10+3 mg/L at 20 °C
    • Solubility in water: poor

  • Synonyms

    • Ethylene glycol dibutyl ether
    • 112-48-1
    • 1,2-DIBUTOXYETHANE
    • Ethylene glycol di-n-butyl ether
    • Glycol dibutyl ether
    • Dibutyl cellosolve
    • Dibutyl Oxitol
    • Ethane, 1,2-dibutoxy-
    • 1-(2-Butoxyethoxy)butane
    • ETHYLENEGLYCOLDI-N-BUTYLETHER
    • HSDB 2827
    • Dibutylether ethylenglykolu
    • Ethyl glycol dibutyl ether
    • EINECS 203-976-8
    • UNII-1HZO49D869
    • BRN 1738358
    • AI3-19429
    • 1HZO49D869
    • Butane, 1,1'-(1,2-ethanediylbis(oxy))bis-
    • MFCD00048785
    • DTXSID5074268
    • 4-01-00-02382 (Beilstein Handbook Reference)
    • BUTANE, 1-(2-BUTOXYETHOXY)-
    • ETHYLENE GLYCOL DIBUTYL ETHER [HSDB]
    • Butane, 1,1'-[1,2-ethanediylbis(oxy)]bis-
    • Dibutylether ethylenglykolu [Czech]
    • Dibutyl Glycol
    • 1,2dibutoxyethane
    • EGDBE
    • 1,2-dibutoxy ethane
    • 1,2-dibutoxy-ethane
    • Ethane, 1,2dibutoxy
    • SCHEMBL30673
    • 1-(2-Butoxyethoxy)butane #
    • ETHYLENE GLYCOL DIBUTYL
    • ETHANE, 1,2-DIBUTOXY
    • DTXCID9033262
    • ETHER ETHYLENE GLYCOL DIBUTYL
    • AKOS025311491
    • LS-13914
    • SY052267
    • Butane, 1,1'(1,2ethanediylbis(oxy))bis
    • 1,1'-(1,2-Ethanediylbis(oxy))bis-butane
    • CS-0187426
    • E0217
    • NS00021529
    • F14779
    • Q27252436

  • Applications

    Ethylene glycol dibutyl ether (CAS number: 112-48-1) is a high-boiling glycol ether used as a solvent in a range of industrial formulations. In coatings and printing inks it serves as a solvent and co-solvent for resins and additives, aiding flow, film formation, and pigment dispersion. It is widely used in cleaning and degreasing formulations for metalworking, electronics, and precision components due to its solvency for oils, waxes, and residues. It also functions as a solvent component in adhesive formulations to adjust viscosity and cure characteristics. Additionally, it is employed as a processing solvent in the manufacture of certain polymers and specialty resins, where it helps dissolve monomers and facilitate formulation.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 961.48
    methanol 793.5
    isopropanol 1019.67
    water 0.23
    ethyl acetate 1492.31
    n-propanol 1061.51
    acetone 1764.64
    n-butanol 1208.77
    acetonitrile 1132.69
    DMF 1034.09
    toluene 840.29
    isobutanol 923.21
    1,4-dioxane 2041.0
    methyl acetate 1105.27
    THF 3002.48
    2-butanone 1385.96
    n-pentanol 787.09
    sec-butanol 1155.51
    n-hexane 1143.77
    ethylene glycol 141.53
    NMP 1430.62
    cyclohexane 2639.48
    DMSO 2055.01
    n-butyl acetate 2003.99
    n-octanol 566.95
    chloroform 6695.4
    n-propyl acetate 1356.29
    acetic acid 1340.43
    dichloromethane 5675.79
    cyclohexanone 3381.28
    propylene glycol 276.63
    isopropyl acetate 937.44
    DMAc 823.17
    2-ethoxyethanol 851.09
    isopentanol 1067.31
    n-heptane 1118.71
    ethyl formate 860.79
    1,2-dichloroethane 3365.19
    n-hexanol 1164.84
    2-methoxyethanol 1139.22
    isobutyl acetate 755.65
    tetrachloromethane 1697.39
    n-pentyl acetate 1128.09
    transcutol 2719.13
    n-heptanol 510.79
    ethylbenzene 601.38
    MIBK 726.37
    2-propoxyethanol 1185.8
    tert-butanol 1498.06
    MTBE 1279.07
    2-butoxyethanol 755.44
    propionic acid 1066.22
    o-xylene 603.12
    formic acid 209.05
    diethyl ether 1552.99
    m-xylene 547.5
    p-xylene 808.71
    chlorobenzene 1597.59
    dimethyl carbonate 263.03
    n-octane 296.82
    formamide 305.24
    cyclopentanone 2619.71
    2-pentanone 1342.25
    anisole 739.11
    cyclopentyl methyl ether 1871.84
    gamma-butyrolactone 2489.86
    1-methoxy-2-propanol 929.44
    pyridine 2296.8
    3-pentanone 1068.87
    furfural 2064.19
    n-dodecane 140.95
    diethylene glycol 583.82
    diisopropyl ether 551.54
    tert-amyl alcohol 1249.86
    acetylacetone 1131.17
    n-hexadecane 166.27
    acetophenone 787.25
    methyl propionate 885.32
    isopentyl acetate 1490.51
    trichloroethylene 5545.33
    n-nonanol 507.21
    cyclohexanol 2055.95
    benzyl alcohol 645.78
    2-ethylhexanol 1092.78
    isooctanol 482.76
    dipropyl ether 1773.96
    1,2-dichlorobenzene 1567.76
    ethyl lactate 437.48
    propylene carbonate 1511.63
    n-methylformamide 585.25
    2-pentanol 1015.87
    n-pentane 796.99
    1-propoxy-2-propanol 1293.14
    1-methoxy-2-propyl acetate 951.75
    2-(2-methoxypropoxy) propanol 602.55
    mesitylene 412.43
    ε-caprolactone 2447.78
    p-cymene 578.54
    epichlorohydrin 2611.22
    1,1,1-trichloroethane 4088.96
    2-aminoethanol 351.32
    morpholine-4-carbaldehyde 1287.17
    sulfolane 2998.67
    2,2,4-trimethylpentane 291.72
    2-methyltetrahydrofuran 2815.45
    n-hexyl acetate 1280.3
    isooctane 189.94
    2-(2-butoxyethoxy)ethanol 840.91
    sec-butyl acetate 828.74
    tert-butyl acetate 1003.58
    decalin 599.87
    glycerin 324.69
    diglyme 1733.38
    acrylic acid 847.46
    isopropyl myristate 502.39
    n-butyric acid 1943.12
    acetyl acetate 982.13
    di(2-ethylhexyl) phthalate 379.27
    ethyl propionate 1029.17
    nitromethane 1720.61
    1,2-diethoxyethane 1565.77
    benzonitrile 1171.31
    trioctyl phosphate 307.45
    1-bromopropane 2744.9
    gamma-valerolactone 2398.95
    n-decanol 355.17
    triethyl phosphate 583.83
    4-methyl-2-pentanol 513.13
    propionitrile 1203.74
    vinylene carbonate 1260.48
    1,1,2-trichlorotrifluoroethane 2069.85
    DMS 681.42
    cumene 435.83
    2-octanol 428.8
    2-hexanone 1191.97
    octyl acetate 563.48
    limonene 1116.39
    1,2-dimethoxyethane 1759.33
    ethyl orthosilicate 613.85
    tributyl phosphate 463.88
    diacetone alcohol 804.89
    N,N-dimethylaniline 514.16
    acrylonitrile 1211.29
    aniline 981.06
    1,3-propanediol 593.47
    bromobenzene 1898.93
    dibromomethane 4792.15
    1,1,2,2-tetrachloroethane 5081.61
    2-methyl-cyclohexyl acetate 1000.57
    tetrabutyl urea 537.72
    diisobutyl methanol 680.85
    2-phenylethanol 676.42
    styrene 788.93
    dioctyl adipate 737.87
    dimethyl sulfate 485.7
    ethyl butyrate 1520.76
    methyl lactate 383.65
    butyl lactate 748.05
    diethyl carbonate 874.67
    propanediol butyl ether 632.14
    triethyl orthoformate 1060.1
    p-tert-butyltoluene 524.76
    methyl 4-tert-butylbenzoate 654.73
    morpholine 2416.23
    tert-butylamine 1313.57
    n-dodecanol 280.3
    dimethoxymethane 672.47
    ethylene carbonate 1202.25
    cyrene 532.38
    2-ethoxyethyl acetate 922.75
    2-ethylhexyl acetate 1324.3
    1,2,4-trichlorobenzene 1642.55
    4-methylpyridine 1836.03
    dibutyl ether 1515.22
    2,6-dimethyl-4-heptanol 680.85
    DEF 1291.38
    dimethyl isosorbide 1091.17
    tetrachloroethylene 3695.0
    eugenol 574.35
    triacetin 948.42
    span 80 785.86
    1,4-butanediol 270.72
    1,1-dichloroethane 3431.02
    2-methyl-1-pentanol 732.78
    methyl formate 481.91
    2-methyl-1-butanol 1001.61
    n-decane 295.04
    butyronitrile 1449.54
    3,7-dimethyl-1-octanol 669.97
    1-chlorooctane 777.92
    1-chlorotetradecane 279.74
    n-nonane 345.72
    undecane 191.31
    tert-butylcyclohexane 449.42
    cyclooctane 663.6
    cyclopentanol 1751.94
    tetrahydropyran 3523.83
    tert-amyl methyl ether 1021.66
    2,5,8-trioxanonane 1009.12
    1-hexene 1718.35
    2-isopropoxyethanol 662.93
    2,2,2-trifluoroethanol 429.91
    methyl butyrate 1564.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction