Ethyl phenyllactate, (+/-)-

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  • Identifiers

    CAS number
    15399-05-0

    Molecular formula
    C11H14O3

    SMILES
    CCOC(=O)C(CC1=CC=CC=C1)O

  • Odor profile

    Fragrance
    Sweet 60.86%
    Honey 56.47%
    Fruity 53.66%
    Floral 46.14%
    Rose 42.42%
    Caramellic 41.55%
    Balsamic 40.41%
    Spicy 40.22%
    Green 28.22%
    Cocoa 27.23%

     

    Flavor
    Fruity 62.47%
    Sweet 59.34%
    Floral 42.09%
    Rose 34.35%
    Mild 32.47%
    Balsam 32.38%
    Honey 31.53%
    Waxy 30.72%
    Grape 30.55%
    Bitter 27.8%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    7.13 (neutral)

    Molecular weight
    194.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    266°C

    Flash point

    • 137.57 ˚C est.

    Solubility expt.

    • Insoluble
    • Soluble (in ethanol)

  • Synonyms

    • ethyl 2-hydroxy-3-phenylpropanoate
    • 15399-05-0
    • Ethyl 2-hydroxy-3-phenylpropionate
    • 3-Phenyllactic acid ethyl ester
    • Ethyl phenyllactate
    • Phenyllactic acid ethyl ester
    • FEMA No. 4598
    • Lactic acid, 3-phenyl-, ethyl ester
    • R64374A2E5
    • (+/-)-ethyl phenyllactate
    • CHEBI:87513
    • DTXSID50934886
    • Propanoic acid, 2-hydroxy-3-phenyl, ethyl ester
    • ETHYL PHENYLLACTATE, (+/-)-
    • Ethyl phenyllactate, (+-)-
    • Ethyl alpha-hydroxyhydrocinnamate
    • UNII-R64374A2E5
    • Benzenepropanoic acid, alpha-hydroxy-, ethyl ester
    • SCHEMBL1245765
    • DTXCID50218335
    • ethyl2-hydroxy-3-phenylpropanoate
    • QAA39905
    • MFCD00128177
    • AKOS008153803
    • AS-77549
    • DA-09910
    • SY186147
    • ETHYL .ALPHA.-HYDROXYHYDROCINNAMATE
    • CS-0198953
    • 2-hydroxy-3-phenyl-propionic acid ethyl ester
    • EN300-82299
    • D97639
    • Benzopropanoic acid, alpha-hydroxy-, ethyl ester
    • Q27159686
    • Z965048074
    • BENZENEPROPANOIC ACID, .ALPHA.-HYDROXY-, ETHYL ESTER

  • Applications

    Ethyl phenyllactate, (+/-)- (CAS 15399-05-0) is used primarily as a chemical intermediate in organic synthesis and as a fragrance/aroma ingredient. In perfumery and cosmetics, it contributes to fragrance formulations as an aroma note and can act as a precursor for other lactate-derived compounds. It also serves as a building block for pharmaceutical synthesis and related specialty chemicals in the pharmaceutical and fine-chemical sectors. In industrial manufacturing, it is employed as a feedstock for lactate-derived intermediates and related synthetic routes.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 403.52
    methanol 1119.95
    isopropanol 172.44
    water 2.5
    ethyl acetate 292.75
    n-propanol 210.61
    acetone 491.7
    n-butanol 159.95
    acetonitrile 290.91
    DMF 1075.18
    toluene 52.0
    isobutanol 115.77
    1,4-dioxane 461.56
    methyl acetate 245.6
    THF 371.05
    2-butanone 200.31
    n-pentanol 122.08
    sec-butanol 120.06
    n-hexane 4.31
    ethylene glycol 206.5
    NMP 395.6
    cyclohexane 8.21
    DMSO 1327.89
    n-butyl acetate 182.83
    n-octanol 55.28
    chloroform 386.32
    n-propyl acetate 164.25
    acetic acid 617.51
    dichloromethane 455.37
    cyclohexanone 254.24
    propylene glycol 127.14
    isopropyl acetate 141.7
    DMAc 609.76
    2-ethoxyethanol 357.34
    isopentanol 136.03
    n-heptane 3.99
    ethyl formate 175.14
    1,2-dichloroethane 446.13
    n-hexanol 121.63
    2-methoxyethanol 609.58
    isobutyl acetate 103.48
    tetrachloromethane 24.79
    n-pentyl acetate 73.16
    transcutol 1095.12
    n-heptanol 57.04
    ethylbenzene 40.77
    MIBK 130.14
    2-propoxyethanol 274.68
    tert-butanol 305.04
    MTBE 174.18
    2-butoxyethanol 141.73
    propionic acid 218.27
    o-xylene 51.54
    formic acid 399.1
    diethyl ether 188.99
    m-xylene 45.97
    p-xylene 50.56
    chlorobenzene 120.68
    dimethyl carbonate 142.0
    n-octane 3.11
    formamide 667.99
    cyclopentanone 328.2
    2-pentanone 187.34
    anisole 137.81
    cyclopentyl methyl ether 132.16
    gamma-butyrolactone 436.69
    1-methoxy-2-propanol 321.46
    pyridine 239.51
    3-pentanone 134.09
    furfural 374.58
    n-dodecane 3.7
    diethylene glycol 366.49
    diisopropyl ether 40.26
    tert-amyl alcohol 187.66
    acetylacetone 302.7
    n-hexadecane 4.26
    acetophenone 137.89
    methyl propionate 210.28
    isopentyl acetate 148.18
    trichloroethylene 662.71
    n-nonanol 49.76
    cyclohexanol 103.1
    benzyl alcohol 116.88
    2-ethylhexanol 69.44
    isooctanol 47.43
    dipropyl ether 63.49
    1,2-dichlorobenzene 130.72
    ethyl lactate 93.51
    propylene carbonate 215.63
    n-methylformamide 433.94
    2-pentanol 92.26
    n-pentane 3.76
    1-propoxy-2-propanol 157.42
    1-methoxy-2-propyl acetate 174.13
    2-(2-methoxypropoxy) propanol 159.86
    mesitylene 34.53
    ε-caprolactone 226.86
    p-cymene 31.48
    epichlorohydrin 490.65
    1,1,1-trichloroethane 165.06
    2-aminoethanol 257.35
    morpholine-4-carbaldehyde 440.2
    sulfolane 542.91
    2,2,4-trimethylpentane 5.93
    2-methyltetrahydrofuran 193.4
    n-hexyl acetate 113.96
    isooctane 4.67
    2-(2-butoxyethoxy)ethanol 232.61
    sec-butyl acetate 99.15
    tert-butyl acetate 169.0
    decalin 9.09
    glycerin 248.35
    diglyme 448.58
    acrylic acid 254.19
    isopropyl myristate 44.37
    n-butyric acid 270.73
    acetyl acetate 201.92
    di(2-ethylhexyl) phthalate 52.92
    ethyl propionate 132.08
    nitromethane 1018.37
    1,2-diethoxyethane 216.99
    benzonitrile 122.29
    trioctyl phosphate 37.56
    1-bromopropane 115.11
    gamma-valerolactone 418.88
    n-decanol 38.56
    triethyl phosphate 59.6
    4-methyl-2-pentanol 61.56
    propionitrile 165.04
    vinylene carbonate 215.23
    1,1,2-trichlorotrifluoroethane 380.84
    DMS 136.04
    cumene 33.71
    2-octanol 35.09
    2-hexanone 125.28
    octyl acetate 57.7
    limonene 45.2
    1,2-dimethoxyethane 461.16
    ethyl orthosilicate 55.78
    tributyl phosphate 50.78
    diacetone alcohol 222.11
    N,N-dimethylaniline 91.86
    acrylonitrile 265.18
    aniline 106.75
    1,3-propanediol 304.73
    bromobenzene 108.66
    dibromomethane 233.98
    1,1,2,2-tetrachloroethane 505.96
    2-methyl-cyclohexyl acetate 85.97
    tetrabutyl urea 69.59
    diisobutyl methanol 43.19
    2-phenylethanol 108.48
    styrene 56.87
    dioctyl adipate 73.47
    dimethyl sulfate 253.67
    ethyl butyrate 109.5
    methyl lactate 148.84
    butyl lactate 80.96
    diethyl carbonate 86.71
    propanediol butyl ether 144.51
    triethyl orthoformate 77.31
    p-tert-butyltoluene 30.41
    methyl 4-tert-butylbenzoate 110.73
    morpholine 435.67
    tert-butylamine 125.7
    n-dodecanol 30.14
    dimethoxymethane 439.48
    ethylene carbonate 180.04
    cyrene 147.08
    2-ethoxyethyl acetate 138.81
    2-ethylhexyl acetate 102.08
    1,2,4-trichlorobenzene 146.69
    4-methylpyridine 177.93
    dibutyl ether 63.82
    2,6-dimethyl-4-heptanol 43.19
    DEF 278.01
    dimethyl isosorbide 226.71
    tetrachloroethylene 310.36
    eugenol 124.02
    triacetin 135.45
    span 80 110.44
    1,4-butanediol 128.46
    1,1-dichloroethane 226.41
    2-methyl-1-pentanol 104.68
    methyl formate 346.77
    2-methyl-1-butanol 113.45
    n-decane 5.37
    butyronitrile 142.11
    3,7-dimethyl-1-octanol 57.88
    1-chlorooctane 32.01
    1-chlorotetradecane 13.66
    n-nonane 4.64
    undecane 4.38
    tert-butylcyclohexane 8.45
    cyclooctane 3.28
    cyclopentanol 100.75
    tetrahydropyran 231.11
    tert-amyl methyl ether 123.74
    2,5,8-trioxanonane 311.25
    1-hexene 29.29
    2-isopropoxyethanol 198.96
    2,2,2-trifluoroethanol 192.47
    methyl butyrate 185.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction