Ethyl iso-amyl ketone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    624-42-0

    Molecular formula
    C8H16O

    SMILES
    CCC(=O)CCC(C)C

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 90.34%
    Herbal 77.27%
    Ketonic 58.71%
    Cheesy 46.81%
    Sweet 46.58%
    Mint 46.23%
    Green 39.15%
    Fresh 36.78%
    Oily 35.34%
    Spicy 32.76%

     

    Flavor
    Fruity 53.38%
    Green 43.73%
    Herbal 31.9%
    Ethereal 29.79%
    Fresh 24.77%
    Oily 24.36%
    Tropical 23.28%
    Cheese 22.8%
    Sweaty 21.8%
    Mushroom 21.51%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    9.11 (weak base)

    Molecular weight
    128.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point

    • 164 °C

    Flash point

    • 46.45 ˚C est.

    Solubility expt.

    • Soluble in ethanol, ether, benzene, carbon tetrachloride, organic solvents

  • Synonyms

    • 2-Methyl-5-heptanone
    • 6-Methylheptan-3-one
    • 624-42-0
    • Ethyl isoamyl ketone
    • 6-Methyl-3-heptanone
    • 3-Heptanone, 6-methyl-
    • ETHYL ISO-AMYL KETONE
    • 6-methylheptane-3-one
    • AOG1YZD9QO
    • HSDB 2841
    • EINECS 210-844-3
    • DTXSID20211454
    • 6-METHYL-3-HEPTANONE [HSDB]
    • UNII-AOG1YZD9QO
    • 6methylheptan3one
    • 6Methyl3heptanone
    • 6methylheptane3one
    • 3Heptanone, 6methyl
    • 6-methyl-heptan-3-one
    • SCHEMBL108580
    • DTXCID20133945
    • CHEBI:195864
    • LMFA12000042
    • DB-054165
    • NS00022540
    • G47223
    • EN300-7033298
    • Q63392282
    • 210-844-3

  • Applications

    Ethyl iso-amyl ketone (CAS 624-42-0) is used as a versatile solvent and intermediate across several industrial sectors: as a fragrance ingredient and odorant in perfumery; as a solvent or processing aid in cosmetics and personal care formulations; as a cleaning and degreasing solvent in household and industrial cleaners; as a solvent for coatings and inks in paints and related products; and as an intermediate or processing solvent in industrial manufacturing and polymer synthesis. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 706.6
    methanol 539.5
    isopropanol 809.44
    water 1.23
    ethyl acetate 261.59
    n-propanol 594.07
    acetone 390.02
    n-butanol 611.55
    acetonitrile 353.91
    DMF 384.66
    toluene 219.44
    isobutanol 509.59
    1,4-dioxane 573.51
    methyl acetate 295.84
    THF 725.2
    2-butanone 415.93
    n-pentanol 404.87
    sec-butanol 670.39
    n-hexane 196.56
    ethylene glycol 125.75
    NMP 343.92
    cyclohexane 178.39
    DMSO 306.56
    n-butyl acetate 459.89
    n-octanol 351.39
    chloroform 1494.44
    n-propyl acetate 206.16
    acetic acid 370.02
    dichloromethane 860.11
    cyclohexanone 559.54
    propylene glycol 281.06
    isopropyl acetate 193.45
    DMAc 362.54
    2-ethoxyethanol 323.87
    isopentanol 524.07
    n-heptane 149.7
    ethyl formate 225.4
    1,2-dichloroethane 377.86
    n-hexanol 700.92
    2-methoxyethanol 516.07
    isobutyl acetate 169.6
    tetrachloromethane 270.9
    n-pentyl acetate 270.35
    transcutol 826.5
    n-heptanol 332.29
    ethylbenzene 182.26
    MIBK 207.36
    2-propoxyethanol 566.14
    tert-butanol 811.31
    MTBE 436.97
    2-butoxyethanol 393.26
    propionic acid 375.55
    o-xylene 171.61
    formic acid 93.28
    diethyl ether 308.82
    m-xylene 164.32
    p-xylene 246.92
    chlorobenzene 318.46
    dimethyl carbonate 57.6
    n-octane 62.62
    formamide 95.17
    cyclopentanone 512.56
    2-pentanone 282.59
    anisole 266.4
    cyclopentyl methyl ether 315.87
    gamma-butyrolactone 451.53
    1-methoxy-2-propanol 451.53
    pyridine 556.39
    3-pentanone 189.06
    furfural 524.17
    n-dodecane 48.51
    diethylene glycol 331.07
    diisopropyl ether 111.8
    tert-amyl alcohol 615.46
    acetylacetone 233.96
    n-hexadecane 52.93
    acetophenone 243.15
    methyl propionate 175.12
    isopentyl acetate 437.13
    trichloroethylene 816.77
    n-nonanol 290.22
    cyclohexanol 510.78
    benzyl alcohol 261.75
    2-ethylhexanol 436.09
    isooctanol 261.79
    dipropyl ether 302.41
    1,2-dichlorobenzene 291.36
    ethyl lactate 131.4
    propylene carbonate 349.76
    n-methylformamide 199.61
    2-pentanol 431.39
    n-pentane 135.06
    1-propoxy-2-propanol 507.24
    1-methoxy-2-propyl acetate 288.39
    2-(2-methoxypropoxy) propanol 324.48
    mesitylene 116.14
    ε-caprolactone 484.89
    p-cymene 176.54
    epichlorohydrin 513.11
    1,1,1-trichloroethane 596.02
    2-aminoethanol 300.47
    morpholine-4-carbaldehyde 438.55
    sulfolane 457.04
    2,2,4-trimethylpentane 66.7
    2-methyltetrahydrofuran 645.12
    n-hexyl acetate 411.14
    isooctane 55.89
    2-(2-butoxyethoxy)ethanol 407.72
    sec-butyl acetate 169.25
    tert-butyl acetate 212.82
    decalin 95.37
    glycerin 256.55
    diglyme 582.93
    acrylic acid 275.76
    isopropyl myristate 171.63
    n-butyric acid 538.2
    acetyl acetate 157.13
    di(2-ethylhexyl) phthalate 169.68
    ethyl propionate 159.58
    nitromethane 324.95
    1,2-diethoxyethane 322.95
    benzonitrile 421.29
    trioctyl phosphate 131.46
    1-bromopropane 433.92
    gamma-valerolactone 607.08
    n-decanol 211.66
    triethyl phosphate 137.34
    4-methyl-2-pentanol 256.24
    propionitrile 405.29
    vinylene carbonate 322.71
    1,1,2-trichlorotrifluoroethane 463.87
    DMS 183.56
    cumene 149.12
    2-octanol 263.76
    2-hexanone 289.22
    octyl acetate 213.52
    limonene 270.79
    1,2-dimethoxyethane 502.17
    ethyl orthosilicate 135.45
    tributyl phosphate 155.34
    diacetone alcohol 299.23
    N,N-dimethylaniline 193.29
    acrylonitrile 398.77
    aniline 282.5
    1,3-propanediol 398.42
    bromobenzene 334.03
    dibromomethane 673.16
    1,1,2,2-tetrachloroethane 779.69
    2-methyl-cyclohexyl acetate 260.09
    tetrabutyl urea 183.75
    diisobutyl methanol 228.33
    2-phenylethanol 335.95
    styrene 209.16
    dioctyl adipate 221.57
    dimethyl sulfate 88.93
    ethyl butyrate 279.11
    methyl lactate 138.74
    butyl lactate 245.79
    diethyl carbonate 180.66
    propanediol butyl ether 403.99
    triethyl orthoformate 207.49
    p-tert-butyltoluene 175.53
    methyl 4-tert-butylbenzoate 256.27
    morpholine 707.12
    tert-butylamine 566.04
    n-dodecanol 164.12
    dimethoxymethane 184.22
    ethylene carbonate 261.0
    cyrene 214.77
    2-ethoxyethyl acetate 259.92
    2-ethylhexyl acetate 346.67
    1,2,4-trichlorobenzene 352.47
    4-methylpyridine 549.98
    dibutyl ether 302.25
    2,6-dimethyl-4-heptanol 228.33
    DEF 256.51
    dimethyl isosorbide 412.38
    tetrachloroethylene 472.81
    eugenol 268.74
    triacetin 291.13
    span 80 379.8
    1,4-butanediol 179.49
    1,1-dichloroethane 645.06
    2-methyl-1-pentanol 360.13
    methyl formate 134.17
    2-methyl-1-butanol 458.39
    n-decane 78.99
    butyronitrile 509.09
    3,7-dimethyl-1-octanol 347.73
    1-chlorooctane 218.55
    1-chlorotetradecane 91.13
    n-nonane 82.48
    undecane 59.87
    tert-butylcyclohexane 102.67
    cyclooctane 62.7
    cyclopentanol 507.92
    tetrahydropyran 685.91
    tert-amyl methyl ether 299.64
    2,5,8-trioxanonane 418.93
    1-hexene 420.55
    2-isopropoxyethanol 273.59
    2,2,2-trifluoroethanol 103.16
    methyl butyrate 244.48

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction