Ethyl (E,E,Z)-tetradeca-2,4,8-trienoate

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  • Identifiers

    CAS number
    28380-12-3

    Molecular formula
    C16H26O2

    SMILES
    CCCCC/C=C\CC/C=C/C=C/C(=O)OCC

    Safety labels

  • Odor profile

    Fragrance
    Fatty 85.45%
    Fruity 58.55%
    Green 57.34%
    Oily 56.51%
    Pear 52.14%
    Waxy 52.13%
    Melon 42.22%
    Citrus 36.94%
    Fishy 28.91%
    Dairy 28.61%

     

    Flavor
    Fatty 32.92%
    Waxy 28.74%
    Pear 28.05%
    Fruity 27.13%
    Green 26.59%
    Melon 26.46%
    Sweet 24.62%
    Oily 23.77%
    Pumpkin 21.18%
    Oriental 20.48%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.2

    pKa est.
    7.81 (neutral)

    Molecular weight
    250.38 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    304°C

    Flash point

    • 157.18 ˚C est.

  • Synonyms

    • ethyl (2E,4E,8Z)-tetradeca-2,4,8-trienoate
    • 28380-12-3
    • Ethyl (E,E,Z)-tetradeca-2,4,8-trienoate
    • EINECS 248-999-4
    • MDUHULUQDWKICH-RFYAXJIXSA-N
    • DTXSID901225785
    • 2,4,8-Tetradecatrienoic acid, ethyl ester, (E,E,Z)-
    • 28380-12-3

  • Applications

    Ethyl (E,E,Z)-tetradeca-2,4,8-trienoate (CAS 28380-12-3) is a long-chain fatty acid ester that may find use across several industry sectors as a chemical intermediate and formulation component. In fragrance and perfumery, it may serve as an aroma ingredient and/or a fixative to help stabilize and extend scent; in cosmetics and personal care, it can act as a solvent or emollient and as a vehicle for other actives and fragrances. In industrial manufacturing, it may be used as an intermediate for the synthesis of specialty esters and high-molecule compounds; in polymers and coatings, it may function as a potential plasticizer or processing aid to adjust rheology and compatibility. Additionally, it may appear in cleaning formulations as a solvent or fragrance carrier, depending on formulation goals and local regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1954.7
    methanol 1996.24
    isopropanol 1348.34
    water 0.02
    ethyl acetate 2128.67
    n-propanol 1499.57
    acetone 3300.65
    n-butanol 1293.05
    acetonitrile 1283.1
    DMF 2186.9
    toluene 892.37
    isobutanol 1003.93
    1,4-dioxane 2100.76
    methyl acetate 1288.13
    THF 3933.02
    2-butanone 2301.93
    n-pentanol 968.53
    sec-butanol 1309.86
    n-hexane 237.25
    ethylene glycol 73.12
    NMP 1776.32
    cyclohexane 487.35
    DMSO 3699.97
    n-butyl acetate 1312.07
    n-octanol 231.82
    chloroform 3155.71
    n-propyl acetate 1352.74
    acetic acid 796.92
    dichloromethane 4177.89
    cyclohexanone 3131.72
    propylene glycol 210.11
    isopropyl acetate 1234.85
    DMAc 1831.69
    2-ethoxyethanol 1141.89
    isopentanol 1047.68
    n-heptane 80.62
    ethyl formate 666.01
    1,2-dichloroethane 3403.44
    n-hexanol 742.21
    2-methoxyethanol 1731.65
    isobutyl acetate 736.85
    tetrachloromethane 409.63
    n-pentyl acetate 697.82
    transcutol 3821.26
    n-heptanol 237.29
    ethylbenzene 390.06
    MIBK 1081.23
    2-propoxyethanol 1092.79
    tert-butanol 1400.1
    MTBE 2025.91
    2-butoxyethanol 528.71
    propionic acid 643.52
    o-xylene 398.66
    formic acid 131.67
    diethyl ether 2879.81
    m-xylene 476.44
    p-xylene 436.77
    chlorobenzene 972.46
    dimethyl carbonate 323.08
    n-octane 28.17
    formamide 282.11
    cyclopentanone 2701.06
    2-pentanone 2268.9
    anisole 741.35
    cyclopentyl methyl ether 2166.03
    gamma-butyrolactone 2082.77
    1-methoxy-2-propanol 1332.34
    pyridine 2169.0
    3-pentanone 1407.6
    furfural 1258.49
    n-dodecane 19.36
    diethylene glycol 492.95
    diisopropyl ether 510.06
    tert-amyl alcohol 1270.8
    acetylacetone 1646.78
    n-hexadecane 23.72
    acetophenone 682.54
    methyl propionate 1338.97
    isopentyl acetate 1072.74
    trichloroethylene 4168.46
    n-nonanol 211.43
    cyclohexanol 1342.02
    benzyl alcohol 541.33
    2-ethylhexanol 449.5
    isooctanol 223.7
    dipropyl ether 850.53
    1,2-dichlorobenzene 790.64
    ethyl lactate 330.97
    propylene carbonate 931.37
    n-methylformamide 767.68
    2-pentanol 949.94
    n-pentane 162.1
    1-propoxy-2-propanol 872.63
    1-methoxy-2-propyl acetate 1002.37
    2-(2-methoxypropoxy) propanol 544.99
    mesitylene 284.28
    ε-caprolactone 1874.42
    p-cymene 183.52
    epichlorohydrin 3100.88
    1,1,1-trichloroethane 2054.23
    2-aminoethanol 344.62
    morpholine-4-carbaldehyde 1412.04
    sulfolane 2542.55
    2,2,4-trimethylpentane 80.32
    2-methyltetrahydrofuran 3243.03
    n-hexyl acetate 827.7
    isooctane 59.38
    2-(2-butoxyethoxy)ethanol 782.43
    sec-butyl acetate 878.46
    tert-butyl acetate 1238.12
    decalin 147.28
    glycerin 226.34
    diglyme 1544.23
    acrylic acid 370.26
    isopropyl myristate 267.76
    n-butyric acid 1343.37
    acetyl acetate 783.21
    di(2-ethylhexyl) phthalate 217.77
    ethyl propionate 1069.53
    nitromethane 1565.46
    1,2-diethoxyethane 1553.36
    benzonitrile 701.26
    trioctyl phosphate 154.38
    1-bromopropane 2417.88
    gamma-valerolactone 2508.23
    n-decanol 145.02
    triethyl phosphate 294.69
    4-methyl-2-pentanol 403.91
    propionitrile 1037.69
    vinylene carbonate 703.63
    1,1,2-trichlorotrifluoroethane 1349.02
    DMS 546.81
    cumene 224.96
    2-octanol 184.3
    2-hexanone 1436.92
    octyl acetate 324.93
    limonene 368.07
    1,2-dimethoxyethane 1992.95
    ethyl orthosilicate 301.28
    tributyl phosphate 232.17
    diacetone alcohol 1032.42
    N,N-dimethylaniline 450.15
    acrylonitrile 944.33
    aniline 897.03
    1,3-propanediol 611.63
    bromobenzene 1175.45
    dibromomethane 2912.73
    1,1,2,2-tetrachloroethane 3415.97
    2-methyl-cyclohexyl acetate 592.09
    tetrabutyl urea 321.79
    diisobutyl methanol 237.08
    2-phenylethanol 503.39
    styrene 597.74
    dioctyl adipate 416.03
    dimethyl sulfate 514.23
    ethyl butyrate 865.78
    methyl lactate 357.7
    butyl lactate 437.28
    diethyl carbonate 454.97
    propanediol butyl ether 440.11
    triethyl orthoformate 505.77
    p-tert-butyltoluene 172.67
    methyl 4-tert-butylbenzoate 452.46
    morpholine 3261.15
    tert-butylamine 893.28
    n-dodecanol 107.8
    dimethoxymethane 1688.52
    ethylene carbonate 675.03
    cyrene 468.41
    2-ethoxyethyl acetate 900.49
    2-ethylhexyl acetate 838.17
    1,2,4-trichlorobenzene 912.84
    4-methylpyridine 2036.51
    dibutyl ether 716.32
    2,6-dimethyl-4-heptanol 237.08
    DEF 2008.42
    dimethyl isosorbide 973.34
    tetrachloroethylene 1938.4
    eugenol 430.14
    triacetin 652.1
    span 80 492.58
    1,4-butanediol 217.66
    1,1-dichloroethane 2757.94
    2-methyl-1-pentanol 838.25
    methyl formate 414.74
    2-methyl-1-butanol 1082.64
    n-decane 37.76
    butyronitrile 1362.05
    3,7-dimethyl-1-octanol 283.2
    1-chlorooctane 243.46
    1-chlorotetradecane 74.79
    n-nonane 38.27
    undecane 25.46
    tert-butylcyclohexane 113.54
    cyclooctane 92.21
    cyclopentanol 1074.49
    tetrahydropyran 4011.64
    tert-amyl methyl ether 1280.23
    2,5,8-trioxanonane 944.69
    1-hexene 1039.77
    2-isopropoxyethanol 806.47
    2,2,2-trifluoroethanol 138.03
    methyl butyrate 1472.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction