Ethyl Chloride

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  • Identifiers

    CAS number
    75-00-3

    Molecular formula
    C2H5Cl

    SMILES
    CCCl

    Safety labels

    Flammable
    Flammable

    Compressed Gas
    Compressed Gas

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Ethereal 62.3%
    Sweet 52.85%
    Solvent 50.84%
    Alcoholic 50.21%
    Fermented 44.08%
    Gassy 39.17%
    Musty 38.5%
    Pungent 31.3%
    Fishy 29.09%
    Winey 28.04%

     

    Flavor
    Fishy 49.1%
    Onion 33.67%
    Ammoniacal 32.12%
    Sulfurous 32.0%
    Meaty 30.86%
    Ammonia 26.8%
    Garlic 25.18%
    Gassy 25.04%
    Egg 24.33%
    Sulfury 23.87%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 4.2 [mmHg]. Odor threshold from NJ "Hazardous Substance Fact Sheet"
    • 10-12 mg/cu m (recognition in air)

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    8.8 (weak base)

    Molecular weight
    64.51 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -218 °F (NTP, 1992)
    • -138.7 °C
    • -138 °C
    • -218 °F

    Boiling point

    • 54.1 °F at 760 mmHg (NTP, 1992)
    • 12.3 °C @ 760 mm Hg
    • 12.5 °C
    • 54 °F

    Flash point

    • -44.7 ˚C est.
    • -58 °F (NTP, 1992)
    • -50 °C
    • -58 °F (-50 °C) (Closed cup)
    • -50 °C c.c.
    • -58 °F (liquid)
    • NA (Gas) -58 °F (Liquid)

    Solubility expt.

    • 0.574 g/100 mL at 68 °F (NTP, 1992)
    • 0.574 g/100 ml in water @ 20 °C
    • 48.3 g/100 ml in alc
    • 0.447 g/100 g water at 0 °C
    • Solubility: 0.07 g water/100 g ethyl chloride at 0 °C; 103 g acetone/100 g ethyl chloride at 25 °C; 110 g benzene/100 g ethyl chloride at 25 °C; 87 g n-heptane/100 g ethyl chloride at 25 °C; 48 g ethanol/100 g ethyl chloride at 21 °C; 37 g methanol/100 g ethyl chloride at 25 °C; 0.6 G water/100 g ethyl chloride at 20 °C
    • For more Solubility (Complete) data for ETHYL CHLORIDE (6 total), please visit the HSDB record page.
    • Solubility in water, g/100ml at 20 °C: 0.574
    • 0.6%

  • Synonyms

    • Chloroethane
    • ETHYL CHLORIDE
    • Ethane, chloro-
    • 75-00-3
    • Chlorene
    • Chelen
    • Monochloroethane
    • Anodynon
    • Chlorethyl
    • Cloretilo
    • Dublofix
    • Chloryl
    • Ether chloratus
    • Ether muriatic
    • Muriatic ether
    • Aethylis chloridum
    • Chloryl anesthetic
    • Ether hydrochloric
    • Hydrochloric ether
    • Monochlorethane
    • Narcotile
    • Kelene
    • Aethylis
    • Chloridum
    • C2H5Cl
    • Aethylchlorid
    • Chloorethaan
    • Chloroaethan
    • Cloroetano
    • Etylu chlorek
    • mono-chloroethane
    • Cloruro di etile
    • CCRIS 3349
    • HSDB 533
    • Chlorure D'ethyle
    • Chloryle anesthetic
    • NCI-C06224
    • Ethyl chloride [USP]
    • Gebauer's Ethyl Chloride
    • EINECS 200-830-5
    • UNII-46U771ERWK
    • UN1037
    • 46U771ERWK
    • AI3-24474
    • Ethyl chloride (USP)
    • 1-CHLORO-ETHANE
    • EINECS 270-142-8
    • CHLOROETHANE [IARC]
    • UN 1037
    • ETHYL CHLORIDE [MI]
    • ETHYL CHLORIDE [HSDB]
    • ETHYL CHLORIDE [VANDF]
    • ETHYL CHLORIDE [MART.]
    • DTXSID1020302
    • ETHYL CHLORIDE [WHO-DD]
    • CHEBI:47554
    • EC 200-830-5
    • ETHYL CHLORIDE [USP IMPURITY]
    • MFCD00000961
    • Ether chloridum
    • R 160
    • CHLOROETHANE (IARC)
    • Chloorethaan [Dutch]
    • Cloroetano [Italian]
    • ETHYL CHLORIDE (MART.)
    • Chloroaethan [German]
    • ethylchloride
    • Aethylchlorid [German]
    • Aethylchloride
    • Aethylchloride [German]
    • Etylu chlorek [Polish]
    • Chloride, Ethyl
    • ETHYL CHLORIDE (USP IMPURITY)
    • Chlorure d'ethyle [French]
    • Cloruro di etile [Italian]
    • chloranylethane
    • chloroethyl
    • Chloraethan
    • aetyl chloride
    • chloro-ethane
    • ethane, chloro
    • aethylii chloridum
    • 1-Chloroethane #
    • Chloroethane 99%
    • ETHYL CHLORIDE (CHLOROETHANE)
    • ETHANE,CHLORO-
    • CHLOROETHYL GROUP
    • ETHER, HYDROCHLORIC
    • Chloroethane, >=98.0%
    • Chloroethane, >=99.7%
    • Chloroethane, >=99.8%
    • CHEMBL46058
    • DTXCID90302
    • Ethyl chloride (ACGIH:OSHA)
    • NCI-CO6224
    • Ethane, chloro- (8CI,9CI)
    • Chloroethane, purum, >=98.0%
    • AKOS000261558
    • DB13259
    • Chloroethane 100 microg/mL in Methanol
    • Chloroethane 1000 microg/mL in Methanol
    • C2882
    • C2883
    • Ethyl chloride [UN1037] [Flammable gas]
    • F 160
    • NS00019447
    • C18248
    • D04088
    • A838306
    • Q409133
    • Chloroethane (ca. 15% in Tetrahydrofuran, ca. 2.0mol/L)
    • 25052-55-5

  • Applications

    Ethyl chloride (CAS 75-00-3) is used as a versatile industrial solvent with rapid evaporation, primarily for degreasing and cleaning metal parts and electronic components; as a solvent for fats, waxes, oils, and natural extracts (including essential oils) in fragrance, flavor, and processing applications; as a chemical intermediate and/or solvent in organic synthesis to introduce ethyl groups or to form organochlorine derivatives; as a solvent for coatings, inks, and adhesives formulations that benefit from fast evaporation; and as an extraction solvent in fragrance and flavor applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 258.36
    methanol 251.41
    isopropanol 213.25
    water 1.27
    ethyl acetate 275.24
    n-propanol 231.66
    acetone 498.72
    n-butanol 250.4
    acetonitrile 332.93
    DMF 462.78
    toluene 270.51
    isobutanol 179.79
    1,4-dioxane 472.37
    methyl acetate 244.57
    THF 670.69
    2-butanone 361.66
    n-pentanol 156.69
    sec-butanol 212.69
    n-hexane 147.05
    ethylene glycol 66.03
    NMP 542.5
    cyclohexane 321.35
    DMSO 591.75
    n-butyl acetate 425.22
    n-octanol 157.55
    chloroform 974.89
    n-propyl acetate 199.69
    acetic acid 426.97
    dichloromethane 749.39
    cyclohexanone 651.55
    propylene glycol 78.43
    isopropyl acetate 174.36
    DMAc 344.88
    2-ethoxyethanol 160.29
    isopentanol 203.5
    n-heptane 230.89
    ethyl formate 177.86
    1,2-dichloroethane 439.06
    n-hexanol 276.17
    2-methoxyethanol 269.28
    isobutyl acetate 133.77
    tetrachloromethane 298.1
    n-pentyl acetate 219.77
    transcutol 697.63
    n-heptanol 134.78
    ethylbenzene 126.01
    MIBK 165.38
    2-propoxyethanol 288.62
    tert-butanol 254.97
    MTBE 241.89
    2-butoxyethanol 182.2
    propionic acid 243.48
    o-xylene 172.98
    formic acid 89.84
    diethyl ether 296.41
    m-xylene 157.89
    p-xylene 189.16
    chlorobenzene 361.91
    dimethyl carbonate 86.05
    n-octane 71.09
    formamide 103.16
    cyclopentanone 653.26
    2-pentanone 311.34
    anisole 197.47
    cyclopentyl methyl ether 392.85
    gamma-butyrolactone 539.78
    1-methoxy-2-propanol 209.0
    pyridine 543.54
    3-pentanone 259.16
    furfural 515.21
    n-dodecane 44.39
    diethylene glycol 191.27
    diisopropyl ether 103.19
    tert-amyl alcohol 218.49
    acetylacetone 307.58
    n-hexadecane 49.9
    acetophenone 210.71
    methyl propionate 192.33
    isopentyl acetate 309.53
    trichloroethylene 823.91
    n-nonanol 136.48
    cyclohexanol 344.49
    benzyl alcohol 159.95
    2-ethylhexanol 222.0
    isooctanol 110.83
    dipropyl ether 345.25
    1,2-dichlorobenzene 316.62
    ethyl lactate 88.19
    propylene carbonate 311.22
    n-methylformamide 177.93
    2-pentanol 186.25
    n-pentane 142.04
    1-propoxy-2-propanol 305.03
    1-methoxy-2-propyl acetate 236.27
    2-(2-methoxypropoxy) propanol 200.55
    mesitylene 111.83
    ε-caprolactone 430.24
    p-cymene 153.69
    epichlorohydrin 432.32
    1,1,1-trichloroethane 563.83
    2-aminoethanol 105.24
    morpholine-4-carbaldehyde 443.84
    sulfolane 624.35
    2,2,4-trimethylpentane 58.46
    2-methyltetrahydrofuran 570.06
    n-hexyl acetate 276.67
    isooctane 40.35
    2-(2-butoxyethoxy)ethanol 259.22
    sec-butyl acetate 131.59
    tert-butyl acetate 178.53
    decalin 88.55
    glycerin 109.29
    diglyme 471.84
    acrylic acid 235.99
    isopropyl myristate 130.07
    n-butyric acid 343.14
    acetyl acetate 213.89
    di(2-ethylhexyl) phthalate 112.29
    ethyl propionate 161.71
    nitromethane 435.68
    1,2-diethoxyethane 374.32
    benzonitrile 314.0
    trioctyl phosphate 88.5
    1-bromopropane 384.36
    gamma-valerolactone 536.72
    n-decanol 106.79
    triethyl phosphate 130.46
    4-methyl-2-pentanol 94.34
    propionitrile 272.51
    vinylene carbonate 284.43
    1,1,2-trichlorotrifluoroethane 370.69
    DMS 181.35
    cumene 88.38
    2-octanol 114.69
    2-hexanone 236.55
    octyl acetate 154.98
    limonene 271.18
    1,2-dimethoxyethane 338.68
    ethyl orthosilicate 131.04
    tributyl phosphate 118.05
    diacetone alcohol 189.34
    N,N-dimethylaniline 150.33
    acrylonitrile 311.17
    aniline 243.96
    1,3-propanediol 155.68
    bromobenzene 395.36
    dibromomethane 626.12
    1,1,2,2-tetrachloroethane 662.93
    2-methyl-cyclohexyl acetate 198.55
    tetrabutyl urea 166.98
    diisobutyl methanol 147.27
    2-phenylethanol 200.98
    styrene 180.83
    dioctyl adipate 184.92
    dimethyl sulfate 148.6
    ethyl butyrate 275.81
    methyl lactate 98.52
    butyl lactate 157.57
    diethyl carbonate 181.03
    propanediol butyl ether 184.5
    triethyl orthoformate 201.48
    p-tert-butyltoluene 149.39
    methyl 4-tert-butylbenzoate 182.32
    morpholine 470.16
    tert-butylamine 195.4
    n-dodecanol 91.9
    dimethoxymethane 217.41
    ethylene carbonate 230.34
    cyrene 167.6
    2-ethoxyethyl acetate 224.31
    2-ethylhexyl acetate 289.81
    1,2,4-trichlorobenzene 352.0
    4-methylpyridine 511.82
    dibutyl ether 283.78
    2,6-dimethyl-4-heptanol 147.27
    DEF 320.14
    dimethyl isosorbide 335.37
    tetrachloroethylene 503.22
    eugenol 179.08
    triacetin 239.88
    span 80 234.1
    1,4-butanediol 72.96
    1,1-dichloroethane 517.76
    2-methyl-1-pentanol 142.88
    methyl formate 144.38
    2-methyl-1-butanol 194.86
    n-decane 72.0
    butyronitrile 316.2
    3,7-dimethyl-1-octanol 165.55
    1-chlorooctane 166.7
    1-chlorotetradecane 78.94
    n-nonane 82.69
    undecane 53.62
    tert-butylcyclohexane 75.23
    cyclooctane 102.52
    cyclopentanol 329.99
    tetrahydropyran 629.29
    tert-amyl methyl ether 200.66
    2,5,8-trioxanonane 345.31
    1-hexene 262.77
    2-isopropoxyethanol 131.5
    2,2,2-trifluoroethanol 131.96
    methyl butyrate 225.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction