Ethyl 4-methoxyphenylacetate

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  • Identifiers

    CAS number
    14062-18-1

    Molecular formula
    C11H14O3

    SMILES
    CCOC(=O)CC1=CC=C(C=C1)OC

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Floral 79.44%
    Fruity 78.35%
    Sweet 75.53%
    Honey 53.39%
    Powdery 44.64%
    Rose 42.15%
    Anisic 41.4%
    Balsamic 41.25%
    Spicy 39.49%
    Cherry 37.52%

     

    Flavor
    Sweet 84.27%
    Fruity 71.35%
    Floral 69.33%
    Balsam 59.3%
    Honey 50.43%
    Rose 46.89%
    Chocolate 44.69%
    Bitter 44.46%
    Raspberry 40.1%
    Plum 39.21%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    7.25 (neutral)

    Molecular weight
    194.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    275°C

    Flash point

    • 116.58 ˚C est.

  • Synonyms

    • Ethyl 4-methoxyphenylacetate
    • 14062-18-1
    • Ethyl 2-(4-methoxyphenyl)acetate
    • 4-Methoxyphenylacetic acid ethyl ester
    • Benzeneacetic acid, 4-methoxy-, ethyl ester
    • ethyl (4-methoxyphenyl)acetate
    • ethyl p-methoxyphenylacetate
    • p-Methoxyphenylacetic acid ethyl ester
    • Ethyl 2-(p-anisyl)acetate
    • BKJ8K98X9T
    • EINECS 237-903-6
    • ETHYL 4-METHOXYBENZENEACETATE
    • NSC-24760
    • (4-Methoxyphenyl)acetic acid ethyl ester
    • 2-(p-methoxyphenyl)acetic acid ethyl ester
    • AI3-31085
    • DTXSID60161444
    • NSC 24760
    • ACETIC ACID, (P-METHOXYPHENYL)-, ETHYL ESTER
    • RefChem:138776
    • DTXCID8083935
    • 237-903-6
    • DOCCDOCIYYDLGJ-UHFFFAOYSA-N
    • MFCD00040760
    • (4-methoxy-phenyl)-acetic acid ethyl ester
    • Homoanisic Acid Ethyl Ester
    • Ethyl2-(4-methoxyphenyl)acetate
    • UNII-BKJ8K98X9T
    • SCHEMBL924496
    • CHEMBL473379
    • orb3031177
    • SCHEMBL16115920
    • CHEBI:194789
    • ethyl (4-methoxy-phenyl)-acetate
    • NSC24760
    • AKOS008947872
    • FE37405
    • Benzeneacetic acid,4-methoxy-,ethyl ester
    • BS-15377
    • DA-10571
    • CS-0130376
    • M0793
    • NS00024554
    • ST50406453
    • A50726
    • F241076
    • 14062-18-1

  • Applications

    Ethyl 4-methoxyphenylacetate (CAS number: 14062-18-1) is primarily used as an aroma chemical in perfumery, contributing anisic, sweet, and floral notes and serving as a building block for fragrance formulations. It is also commonly evaluated for use in flavor applications, where it can impart fruity or anisette-like characteristics within regulatory limits. In cosmetics and personal care, it functions as a fragrance ingredient in products such as creams, shampoos, and soaps. In household products, it can act as a fragrance additive in cleaners and air fresheners. Beyond formulation roles, Ethyl 4-methoxyphenylacetate serves as an industrial intermediate for the synthesis of other anisyl derivatives and aroma compounds used in fragrance and flavor chemistries.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 410.3
    methanol 560.36
    isopropanol 317.6
    water 2.21
    ethyl acetate 239.71
    n-propanol 265.34
    acetone 221.88
    n-butanol 227.49
    acetonitrile 363.37
    DMF 423.73
    toluene 103.84
    isobutanol 152.09
    1,4-dioxane 793.6
    methyl acetate 226.8
    THF 367.69
    2-butanone 177.92
    n-pentanol 163.47
    sec-butanol 197.64
    n-hexane 8.7
    ethylene glycol 152.02
    NMP 180.74
    cyclohexane 22.57
    DMSO 541.49
    n-butyl acetate 78.73
    n-octanol 43.16
    chloroform 823.88
    n-propyl acetate 86.41
    acetic acid 429.47
    dichloromethane 701.41
    cyclohexanone 201.22
    propylene glycol 173.64
    isopropyl acetate 86.85
    DMAc 456.53
    2-ethoxyethanol 409.28
    isopentanol 137.51
    n-heptane 5.12
    ethyl formate 147.33
    1,2-dichloroethane 381.43
    n-hexanol 102.77
    2-methoxyethanol 659.46
    isobutyl acetate 52.58
    tetrachloromethane 61.48
    n-pentyl acetate 39.62
    transcutol 576.34
    n-heptanol 37.23
    ethylbenzene 53.62
    MIBK 66.78
    2-propoxyethanol 239.66
    tert-butanol 394.66
    MTBE 154.72
    2-butoxyethanol 99.2
    propionic acid 199.52
    o-xylene 67.03
    formic acid 234.88
    diethyl ether 190.91
    m-xylene 57.07
    p-xylene 68.69
    chlorobenzene 141.54
    dimethyl carbonate 72.45
    n-octane 3.43
    formamide 317.14
    cyclopentanone 163.56
    2-pentanone 110.68
    anisole 163.15
    cyclopentyl methyl ether 114.05
    gamma-butyrolactone 217.61
    1-methoxy-2-propanol 357.46
    pyridine 378.77
    3-pentanone 95.25
    furfural 312.71
    n-dodecane 4.42
    diethylene glycol 277.43
    diisopropyl ether 29.05
    tert-amyl alcohol 210.07
    acetylacetone 153.3
    n-hexadecane 4.98
    acetophenone 124.23
    methyl propionate 153.5
    isopentyl acetate 69.68
    trichloroethylene 601.13
    n-nonanol 41.84
    cyclohexanol 178.36
    benzyl alcohol 162.36
    2-ethylhexanol 50.02
    isooctanol 30.34
    dipropyl ether 51.41
    1,2-dichlorobenzene 118.62
    ethyl lactate 67.8
    propylene carbonate 123.75
    n-methylformamide 251.57
    2-pentanol 102.32
    n-pentane 6.84
    1-propoxy-2-propanol 126.63
    1-methoxy-2-propyl acetate 104.78
    2-(2-methoxypropoxy) propanol 123.13
    mesitylene 32.36
    ε-caprolactone 177.37
    p-cymene 25.84
    epichlorohydrin 384.37
    1,1,1-trichloroethane 272.01
    2-aminoethanol 248.4
    morpholine-4-carbaldehyde 374.3
    sulfolane 221.96
    2,2,4-trimethylpentane 6.26
    2-methyltetrahydrofuran 226.58
    n-hexyl acetate 67.02
    isooctane 4.01
    2-(2-butoxyethoxy)ethanol 166.39
    sec-butyl acetate 57.16
    tert-butyl acetate 88.77
    decalin 12.93
    glycerin 262.55
    diglyme 295.52
    acrylic acid 173.28
    isopropyl myristate 32.0
    n-butyric acid 232.49
    acetyl acetate 139.56
    di(2-ethylhexyl) phthalate 40.08
    ethyl propionate 87.05
    nitromethane 530.31
    1,2-diethoxyethane 152.77
    benzonitrile 157.46
    trioctyl phosphate 23.2
    1-bromopropane 163.99
    gamma-valerolactone 317.17
    n-decanol 32.88
    triethyl phosphate 49.43
    4-methyl-2-pentanol 45.82
    propionitrile 207.38
    vinylene carbonate 153.75
    1,1,2-trichlorotrifluoroethane 327.27
    DMS 84.08
    cumene 35.05
    2-octanol 26.12
    2-hexanone 87.89
    octyl acetate 39.08
    limonene 35.16
    1,2-dimethoxyethane 489.27
    ethyl orthosilicate 47.21
    tributyl phosphate 34.55
    diacetone alcohol 135.37
    N,N-dimethylaniline 91.83
    acrylonitrile 271.0
    aniline 198.87
    1,3-propanediol 352.01
    bromobenzene 141.52
    dibromomethane 405.88
    1,1,2,2-tetrachloroethane 502.39
    2-methyl-cyclohexyl acetate 62.62
    tetrabutyl urea 46.47
    diisobutyl methanol 30.6
    2-phenylethanol 101.9
    styrene 75.94
    dioctyl adipate 54.4
    dimethyl sulfate 114.88
    ethyl butyrate 67.51
    methyl lactate 100.61
    butyl lactate 47.96
    diethyl carbonate 62.88
    propanediol butyl ether 97.45
    triethyl orthoformate 58.09
    p-tert-butyltoluene 25.83
    methyl 4-tert-butylbenzoate 78.35
    morpholine 788.17
    tert-butylamine 164.02
    n-dodecanol 26.75
    dimethoxymethane 286.3
    ethylene carbonate 127.24
    cyrene 115.7
    2-ethoxyethyl acetate 79.6
    2-ethylhexyl acetate 53.97
    1,2,4-trichlorobenzene 144.39
    4-methylpyridine 268.35
    dibutyl ether 52.32
    2,6-dimethyl-4-heptanol 30.6
    DEF 171.53
    dimethyl isosorbide 155.33
    tetrachloroethylene 287.1
    eugenol 95.17
    triacetin 88.36
    span 80 85.32
    1,4-butanediol 150.92
    1,1-dichloroethane 342.69
    2-methyl-1-pentanol 111.79
    methyl formate 166.27
    2-methyl-1-butanol 127.81
    n-decane 6.52
    butyronitrile 186.77
    3,7-dimethyl-1-octanol 45.09
    1-chlorooctane 26.69
    1-chlorotetradecane 13.88
    n-nonane 5.61
    undecane 5.2
    tert-butylcyclohexane 10.68
    cyclooctane 5.48
    cyclopentanol 157.91
    tetrahydropyran 413.96
    tert-amyl methyl ether 99.13
    2,5,8-trioxanonane 238.22
    1-hexene 46.04
    2-isopropoxyethanol 199.62
    2,2,2-trifluoroethanol 136.72
    methyl butyrate 114.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction