Ethyl 3-hydroxydodecanoate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    183613-15-2

    Molecular formula
    C14H28O3

    SMILES
    CCCCCCCCCC(CC(=O)OCC)O

    Safety labels

  • Odor profile

    Fragrance
    Fruity 70.11%
    Oily 66.8%
    Fatty 61.08%
    Waxy 52.07%
    Floral 50.16%
    Winey 46.13%
    Sweet 43.18%
    Fresh 34.64%
    Peach 34.47%
    Creamy 34.14%

     

    Flavor
    Waxy 54.29%
    Fruity 51.6%
    Oily 48.14%
    Fatty 39.71%
    Soapy 37.43%
    Floral 36.92%
    Green 36.63%
    Mild 34.97%
    Tropical 32.0%
    Sweet 30.42%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.3

    pKa est.
    7.12 (neutral)

    Molecular weight
    244.37 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    301°C

    Flash point

    • 131.28 ˚C est.

  • Synonyms

    • Ethyl 3-hydroxydodecanoate
    • 183613-15-2
    • Dodecanoic acid, 3-hydroxy-, ethyl ester
    • DTXSID20341801
    • RefChem:343450
    • DTXCID40292881
    • CQLRIUYMQWJYSR-UHFFFAOYSA-N
    • ethyl-3-hydroxydodecanoate
    • Ethyl 3-hydroxydodecanoate #
    • SCHEMBL7603346
    • CHEBI:171863
    • MFCD34564301
    • E98407
    • Q67879876
    • 183613-15-2

  • Applications

    Ethyl 3-hydroxydodecanoate may be used as a chemical building block and processing aid across several industries. In cosmetics and personal care, it may serve as an emollient and as a component in skin and hair care formulations. In perfumery, its hydroxy fatty ester structure may be exploited as a fragrance ingredient or odorant with conditioning character. In polymers and plastics, it may act as a plasticizer or processing aid to improve flexibility and processing performance of certain resin systems. In coatings and inks, it may function as a lubricating additive or solvent-like component to influence film formation and flow properties. Additionally, as an intermediate, it may be derivatized or used in chemical synthesis to access longer-chain hydroxy esters.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2853.93
    methanol 3373.93
    isopropanol 2894.16
    water 0.09
    ethyl acetate 1855.9
    n-propanol 2200.19
    acetone 4587.05
    n-butanol 1790.34
    acetonitrile 1346.94
    DMF 3064.68
    toluene 490.73
    isobutanol 1751.49
    1,4-dioxane 2338.2
    methyl acetate 1269.74
    THF 5221.66
    2-butanone 2178.66
    n-pentanol 1163.11
    sec-butanol 1850.22
    n-hexane 248.55
    ethylene glycol 197.29
    NMP 2309.64
    cyclohexane 487.38
    DMSO 5268.73
    n-butyl acetate 1273.16
    n-octanol 371.16
    chloroform 2755.79
    n-propyl acetate 1345.64
    acetic acid 1495.86
    dichloromethane 2515.26
    cyclohexanone 3837.99
    propylene glycol 533.63
    isopropyl acetate 1293.41
    DMAc 1888.53
    2-ethoxyethanol 1303.61
    isopentanol 1577.94
    n-heptane 93.02
    ethyl formate 943.82
    1,2-dichloroethane 2111.44
    n-hexanol 950.69
    2-methoxyethanol 2388.09
    isobutyl acetate 792.96
    tetrachloromethane 415.87
    n-pentyl acetate 794.68
    transcutol 3507.4
    n-heptanol 342.48
    ethylbenzene 286.2
    MIBK 1218.96
    2-propoxyethanol 1290.71
    tert-butanol 3005.78
    MTBE 1988.62
    2-butoxyethanol 742.46
    propionic acid 1221.17
    o-xylene 339.53
    formic acid 288.13
    diethyl ether 1952.88
    m-xylene 367.31
    p-xylene 400.58
    chlorobenzene 769.92
    dimethyl carbonate 306.84
    n-octane 34.64
    formamide 510.91
    cyclopentanone 3597.26
    2-pentanone 2080.75
    anisole 553.68
    cyclopentyl methyl ether 2153.22
    gamma-butyrolactone 3186.74
    1-methoxy-2-propanol 2033.7
    pyridine 1769.64
    3-pentanone 1144.04
    furfural 1731.27
    n-dodecane 22.73
    diethylene glycol 735.29
    diisopropyl ether 462.61
    tert-amyl alcohol 1855.62
    acetylacetone 1849.68
    n-hexadecane 28.11
    acetophenone 608.88
    methyl propionate 1124.9
    isopentyl acetate 1090.59
    trichloroethylene 2945.99
    n-nonanol 314.76
    cyclohexanol 1960.04
    benzyl alcohol 524.47
    2-ethylhexanol 543.78
    isooctanol 310.39
    dipropyl ether 749.92
    1,2-dichlorobenzene 682.02
    ethyl lactate 432.43
    propylene carbonate 1445.43
    n-methylformamide 1253.95
    2-pentanol 1265.25
    n-pentane 160.44
    1-propoxy-2-propanol 1072.94
    1-methoxy-2-propyl acetate 971.35
    2-(2-methoxypropoxy) propanol 609.27
    mesitylene 266.75
    ε-caprolactone 2410.56
    p-cymene 179.99
    epichlorohydrin 3022.72
    1,1,1-trichloroethane 1838.01
    2-aminoethanol 713.48
    morpholine-4-carbaldehyde 1860.64
    sulfolane 3749.32
    2,2,4-trimethylpentane 75.27
    2-methyltetrahydrofuran 3423.07
    n-hexyl acetate 997.61
    isooctane 59.17
    2-(2-butoxyethoxy)ethanol 947.36
    sec-butyl acetate 820.51
    tert-butyl acetate 1383.26
    decalin 143.89
    glycerin 544.29
    diglyme 1768.48
    acrylic acid 694.59
    isopropyl myristate 299.73
    n-butyric acid 2279.62
    acetyl acetate 841.67
    di(2-ethylhexyl) phthalate 262.93
    ethyl propionate 965.13
    nitromethane 2450.79
    1,2-diethoxyethane 1129.94
    benzonitrile 771.11
    trioctyl phosphate 210.96
    1-bromopropane 1409.65
    gamma-valerolactone 3748.0
    n-decanol 204.52
    triethyl phosphate 304.2
    4-methyl-2-pentanol 598.63
    propionitrile 1126.29
    vinylene carbonate 1057.78
    1,1,2-trichlorotrifluoroethane 1732.96
    DMS 559.99
    cumene 200.46
    2-octanol 273.9
    2-hexanone 1414.19
    octyl acetate 377.36
    limonene 385.61
    1,2-dimethoxyethane 2376.9
    ethyl orthosilicate 298.14
    tributyl phosphate 293.08
    diacetone alcohol 1425.89
    N,N-dimethylaniline 367.11
    acrylonitrile 1083.72
    aniline 738.43
    1,3-propanediol 1246.86
    bromobenzene 800.47
    dibromomethane 1825.04
    1,1,2,2-tetrachloroethane 2807.18
    2-methyl-cyclohexyl acetate 595.85
    tetrabutyl urea 377.96
    diisobutyl methanol 286.33
    2-phenylethanol 482.86
    styrene 372.87
    dioctyl adipate 490.08
    dimethyl sulfate 622.53
    ethyl butyrate 789.75
    methyl lactate 525.07
    butyl lactate 617.55
    diethyl carbonate 436.3
    propanediol butyl ether 752.32
    triethyl orthoformate 507.48
    p-tert-butyltoluene 174.37
    methyl 4-tert-butylbenzoate 529.9
    morpholine 3767.6
    tert-butylamine 1604.93
    n-dodecanol 145.05
    dimethoxymethane 1483.15
    ethylene carbonate 1044.03
    cyrene 562.28
    2-ethoxyethyl acetate 884.95
    2-ethylhexyl acetate 790.87
    1,2,4-trichlorobenzene 798.44
    4-methylpyridine 1587.35
    dibutyl ether 692.01
    2,6-dimethyl-4-heptanol 286.33
    DEF 1818.97
    dimethyl isosorbide 1045.47
    tetrachloroethylene 1720.66
    eugenol 459.04
    triacetin 788.44
    span 80 634.72
    1,4-butanediol 420.43
    1,1-dichloroethane 2143.61
    2-methyl-1-pentanol 878.44
    methyl formate 700.1
    2-methyl-1-butanol 1322.25
    n-decane 50.11
    butyronitrile 1470.99
    3,7-dimethyl-1-octanol 396.44
    1-chlorooctane 287.12
    1-chlorotetradecane 87.99
    n-nonane 50.91
    undecane 31.58
    tert-butylcyclohexane 112.51
    cyclooctane 90.93
    cyclopentanol 2281.26
    tetrahydropyran 4256.01
    tert-amyl methyl ether 1114.35
    2,5,8-trioxanonane 1064.6
    1-hexene 874.98
    2-isopropoxyethanol 942.07
    2,2,2-trifluoroethanol 359.79
    methyl butyrate 1472.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction