Ethyl 2-(2-ethoxy-2-oxoethoxy)propionate

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  • Identifiers

    CAS number
    6309-62-2

    Molecular formula
    C9H16O5

    SMILES
    CCOC(=O)COC(C)C(=O)OCC

    Safety labels

  • Odor profile

    Fragrance
    Fruity 84.14%
    Caramellic 58.45%
    Winey 47.68%
    Buttery 47.07%
    Sweet 45.16%
    Creamy 36.79%
    Ethereal 35.27%
    Fatty 34.86%
    Apple 29.86%
    Milky 29.03%

     

    Flavor
    Fruity 82.4%
    Creamy 40.61%
    Bitter 40.59%
    Mild 39.99%
    Wine 38.54%
    Fruit 37.85%
    Grape 36.84%
    Fatty 35.47%
    Waxy 35.29%
    Green 34.64%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.1

    pKa est.
    5.89 (weak acid)

    Molecular weight
    204.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    234°C

    Flash point

    • 105.35 ˚C est.

  • Synonyms

    • 6309-62-2
    • ethyl 2-(2-ethoxy-2-oxoethoxy)propanoate
    • Ethyl 2-(2-ethoxy-2-oxoethoxy)propionate
    • NSC41607
    • EINECS 228-629-8
    • SCHEMBL11798942
    • SFEWOHUGHVHUCA-UHFFFAOYSA-N
    • DTXSID201274979
    • MFCD28972096
    • NSC 41607
    • NSC-41607
    • AKOS037645894
    • ethyl2-(2-ethoxy-2-oxoethoxy)propanoate
    • AS-64649
    • ethyl 2-(2-ethoxy-2-oxo-ethoxy)propanoate
    • NS00044200
    • W16087
    • 6309-62-2

  • Applications

    Ethyl 2-(2-ethoxy-2-oxoethoxy)propionate, CAS number: 6309-62-2, is commonly used as an intermediate in organic synthesis and as a reactive diluent or plasticizer in polymers and coatings. In industrial manufacturing, it provides a versatile building block for the preparation of specialty esters and related derivatives. In coatings and inks, it can function as a solvent and processing aid to improve flow, leveling and curing characteristics. In adhesives, it may act as a solvent or co-reactant in formulations. It can also serve as a processing solvent in cleaning or formulation operations, contributing to formulation flexibility. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 193.41
    methanol 452.93
    isopropanol 136.91
    water 8.0
    ethyl acetate 431.74
    n-propanol 150.33
    acetone 873.24
    n-butanol 127.99
    acetonitrile 797.42
    DMF 1523.29
    toluene 197.03
    isobutanol 115.53
    1,4-dioxane 556.36
    methyl acetate 469.21
    THF 652.14
    2-butanone 423.23
    n-pentanol 126.97
    sec-butanol 133.5
    n-hexane 30.63
    ethylene glycol 113.57
    NMP 1545.16
    cyclohexane 68.18
    DMSO 2288.69
    n-butyl acetate 228.1
    n-octanol 57.96
    chloroform 1065.82
    n-propyl acetate 244.61
    acetic acid 1375.57
    dichloromethane 1466.48
    cyclohexanone 703.99
    propylene glycol 85.35
    isopropyl acetate 224.72
    DMAc 1311.41
    2-ethoxyethanol 370.68
    isopentanol 115.63
    n-heptane 14.85
    ethyl formate 374.14
    1,2-dichloroethane 917.91
    n-hexanol 82.18
    2-methoxyethanol 527.92
    isobutyl acetate 127.67
    tetrachloromethane 142.88
    n-pentyl acetate 137.31
    transcutol 685.7
    n-heptanol 44.04
    ethylbenzene 126.93
    MIBK 167.9
    2-propoxyethanol 220.47
    tert-butanol 238.2
    MTBE 225.59
    2-butoxyethanol 119.47
    propionic acid 451.34
    o-xylene 180.18
    formic acid 674.18
    diethyl ether 243.01
    m-xylene 123.7
    p-xylene 184.02
    chlorobenzene 438.92
    dimethyl carbonate 240.17
    n-octane 7.8
    formamide 985.55
    cyclopentanone 835.53
    2-pentanone 315.36
    anisole 289.42
    cyclopentyl methyl ether 284.52
    gamma-butyrolactone 1179.52
    1-methoxy-2-propanol 299.8
    pyridine 732.75
    3-pentanone 334.81
    furfural 1221.2
    n-dodecane 6.89
    diethylene glycol 234.35
    diisopropyl ether 64.99
    tert-amyl alcohol 223.41
    acetylacetone 571.38
    n-hexadecane 8.18
    acetophenone 363.57
    methyl propionate 389.07
    isopentyl acetate 185.16
    trichloroethylene 1689.72
    n-nonanol 52.11
    cyclohexanol 209.32
    benzyl alcohol 268.56
    2-ethylhexanol 67.5
    isooctanol 39.34
    dipropyl ether 102.25
    1,2-dichlorobenzene 435.63
    ethyl lactate 148.82
    propylene carbonate 587.33
    n-methylformamide 741.57
    2-pentanol 86.97
    n-pentane 23.24
    1-propoxy-2-propanol 145.05
    1-methoxy-2-propyl acetate 228.24
    2-(2-methoxypropoxy) propanol 175.79
    mesitylene 79.38
    ε-caprolactone 658.12
    p-cymene 69.18
    epichlorohydrin 960.16
    1,1,1-trichloroethane 589.47
    2-aminoethanol 156.6
    morpholine-4-carbaldehyde 975.32
    sulfolane 1697.51
    2,2,4-trimethylpentane 20.49
    2-methyltetrahydrofuran 442.31
    n-hexyl acetate 183.52
    isooctane 8.9
    2-(2-butoxyethoxy)ethanol 196.21
    sec-butyl acetate 151.69
    tert-butyl acetate 233.03
    decalin 35.87
    glycerin 209.23
    diglyme 489.55
    acrylic acid 592.39
    isopropyl myristate 70.9
    n-butyric acid 452.02
    acetyl acetate 426.42
    di(2-ethylhexyl) phthalate 91.52
    ethyl propionate 255.36
    nitromethane 2264.46
    1,2-diethoxyethane 231.88
    benzonitrile 411.49
    trioctyl phosphate 58.5
    1-bromopropane 312.12
    gamma-valerolactone 1081.81
    n-decanol 37.75
    triethyl phosphate 136.98
    4-methyl-2-pentanol 54.05
    propionitrile 362.35
    vinylene carbonate 659.16
    1,1,2-trichlorotrifluoroethane 825.37
    DMS 266.51
    cumene 85.12
    2-octanol 36.99
    2-hexanone 223.45
    octyl acetate 91.29
    limonene 103.5
    1,2-dimethoxyethane 640.91
    ethyl orthosilicate 112.92
    tributyl phosphate 91.31
    diacetone alcohol 239.95
    N,N-dimethylaniline 230.41
    acrylonitrile 612.23
    aniline 301.58
    1,3-propanediol 197.98
    bromobenzene 439.22
    dibromomethane 836.51
    1,1,2,2-tetrachloroethane 1111.34
    2-methyl-cyclohexyl acetate 160.66
    tetrabutyl urea 127.75
    diisobutyl methanol 46.79
    2-phenylethanol 153.2
    styrene 191.6
    dioctyl adipate 138.51
    dimethyl sulfate 625.36
    ethyl butyrate 186.61
    methyl lactate 222.32
    butyl lactate 119.63
    diethyl carbonate 158.99
    propanediol butyl ether 125.88
    triethyl orthoformate 140.37
    p-tert-butyltoluene 63.63
    methyl 4-tert-butylbenzoate 216.01
    morpholine 605.1
    tert-butylamine 142.98
    n-dodecanol 30.22
    dimethoxymethane 489.09
    ethylene carbonate 493.1
    cyrene 275.02
    2-ethoxyethyl acetate 208.93
    2-ethylhexyl acetate 157.64
    1,2,4-trichlorobenzene 504.13
    4-methylpyridine 697.14
    dibutyl ether 92.59
    2,6-dimethyl-4-heptanol 46.79
    DEF 541.72
    dimethyl isosorbide 346.65
    tetrachloroethylene 780.58
    eugenol 181.87
    triacetin 262.94
    span 80 140.55
    1,4-butanediol 111.74
    1,1-dichloroethane 602.78
    2-methyl-1-pentanol 129.09
    methyl formate 633.94
    2-methyl-1-butanol 122.43
    n-decane 11.37
    butyronitrile 294.69
    3,7-dimethyl-1-octanol 63.98
    1-chlorooctane 51.73
    1-chlorotetradecane 23.27
    n-nonane 10.91
    undecane 8.46
    tert-butylcyclohexane 24.13
    cyclooctane 19.61
    cyclopentanol 226.0
    tetrahydropyran 405.84
    tert-amyl methyl ether 203.11
    2,5,8-trioxanonane 344.82
    1-hexene 97.6
    2-isopropoxyethanol 210.49
    2,2,2-trifluoroethanol 529.25
    methyl butyrate 339.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction