Ethyl 1-(ethylthio)propyl disulfide

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  • Identifiers

    CAS number
    183554-18-9

    Molecular formula
    C7H16S3

    SMILES
    CCC(SCC)SSCC

    Safety labels

  • Odor profile

    Fragrance
    Sulfurous 82.75%
    Onion 75.2%
    Alliaceous 69.74%
    Garlic 67.33%
    Savory 54.56%
    Meaty 52.95%
    Green 50.26%
    Roasted 50.04%
    Cooked 45.71%
    Vegetable 43.05%

     

    Flavor
    Onion 74.47%
    Sulfurous 67.65%
    Garlic 65.76%
    Green 56.22%
    Alliaceous 45.99%
    Metallic 35.54%
    Sulfury 35.14%
    Cabbage 32.27%
    Cooked 28.67%
    Meaty 28.15%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    4.87 (weak acid)

    Molecular weight
    196.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    248°C

    Flash point

    • 110.81 ˚C est.

  • Synonyms

    • Ethyl 1-(ethylthio)propyl disulfide
    • 183554-18-9
    • RefChem:138473
    • 1-(ethyldisulfanyl)-1-ethylsulfanylpropane
    • 1-(ethyldisulfanyl)-1-(ethylsulfanyl)propane
    • CHEBI:173962
    • DTXSID001292450
    • 1-(ethyldisulanyl)-1-ethylsulanylpropane
    • 183554-18-9

  • Applications

    Ethyl 1-(ethylthio)propyl disulfide (CAS 183554-18-9) is an organosulfur disulfide used primarily as a chemical intermediate and as an odor-active ingredient in specialty formulations. In fragrance and cosmetics, it may function as a sulfur-containing odor note or fixative within perfumery formulations. It is also encountered as a reactive intermediate in the synthesis of further sulfur-containing compounds for industrial manufacturing. In household products, it can be evaluated as a scent component for air fresheners and cleaners where a distinctive sulfur note is desirable. In polymer or materials contexts, it may serve as a precursor in multi-step syntheses of specialty chemicals used in coatings or inks. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1100.93
    methanol 632.63
    isopropanol 1044.6
    water 0.09
    ethyl acetate 3339.42
    n-propanol 1113.36
    acetone 5421.25
    n-butanol 1195.88
    acetonitrile 2384.45
    DMF 5357.68
    toluene 3701.74
    isobutanol 976.7
    1,4-dioxane 6412.35
    methyl acetate 2849.46
    THF 9766.06
    2-butanone 4180.11
    n-pentanol 741.92
    sec-butanol 1083.6
    n-hexane 463.76
    ethylene glycol 134.51
    NMP 5501.19
    cyclohexane 2167.07
    DMSO 4949.19
    n-butyl acetate 4436.14
    n-octanol 896.35
    chloroform 7691.44
    n-propyl acetate 2088.53
    acetic acid 1169.29
    dichloromethane 7385.73
    cyclohexanone 10244.68
    propylene glycol 257.46
    isopropyl acetate 2045.76
    DMAc 3111.96
    2-ethoxyethanol 962.25
    isopentanol 1040.37
    n-heptane 993.61
    ethyl formate 1851.86
    1,2-dichloroethane 5085.99
    n-hexanol 1434.34
    2-methoxyethanol 1687.09
    isobutyl acetate 1338.78
    tetrachloromethane 1962.91
    n-pentyl acetate 2249.39
    transcutol 3299.23
    n-heptanol 723.14
    ethylbenzene 1199.3
    MIBK 1839.22
    2-propoxyethanol 1854.59
    tert-butanol 1521.71
    MTBE 2420.6
    2-butoxyethanol 1043.08
    propionic acid 1147.66
    o-xylene 1673.54
    formic acid 133.57
    diethyl ether 2969.69
    m-xylene 1874.13
    p-xylene 1553.72
    chlorobenzene 4189.75
    dimethyl carbonate 910.58
    n-octane 351.21
    formamide 337.29
    cyclopentanone 9343.42
    2-pentanone 3641.9
    anisole 2068.62
    cyclopentyl methyl ether 4380.92
    gamma-butyrolactone 6776.35
    1-methoxy-2-propanol 1344.4
    pyridine 7070.02
    3-pentanone 2980.53
    furfural 5429.68
    n-dodecane 204.68
    diethylene glycol 836.09
    diisopropyl ether 1050.69
    tert-amyl alcohol 1249.17
    acetylacetone 3856.43
    n-hexadecane 248.99
    acetophenone 1942.78
    methyl propionate 2275.97
    isopentyl acetate 3061.59
    trichloroethylene 9377.29
    n-nonanol 766.47
    cyclohexanol 2552.15
    benzyl alcohol 1212.11
    2-ethylhexanol 1252.38
    isooctanol 617.66
    dipropyl ether 2751.18
    1,2-dichlorobenzene 3272.44
    ethyl lactate 560.55
    propylene carbonate 3511.01
    n-methylformamide 1558.16
    2-pentanol 935.99
    n-pentane 484.46
    1-propoxy-2-propanol 1755.52
    1-methoxy-2-propyl acetate 2479.14
    2-(2-methoxypropoxy) propanol 953.85
    mesitylene 1234.85
    ε-caprolactone 5788.61
    p-cymene 1100.64
    epichlorohydrin 6177.52
    1,1,1-trichloroethane 6265.76
    2-aminoethanol 300.15
    morpholine-4-carbaldehyde 5041.07
    sulfolane 7427.67
    2,2,4-trimethylpentane 239.1
    2-methyltetrahydrofuran 6774.99
    n-hexyl acetate 2522.52
    isooctane 220.19
    2-(2-butoxyethoxy)ethanol 1314.41
    sec-butyl acetate 1311.01
    tert-butyl acetate 2303.56
    decalin 553.57
    glycerin 332.15
    diglyme 3072.29
    acrylic acid 906.14
    isopropyl myristate 1028.28
    n-butyric acid 2073.49
    acetyl acetate 1960.27
    di(2-ethylhexyl) phthalate 730.29
    ethyl propionate 1614.69
    nitromethane 3011.72
    1,2-diethoxyethane 2805.38
    benzonitrile 3103.48
    trioctyl phosphate 603.44
    1-bromopropane 3173.18
    gamma-valerolactone 8786.93
    n-decanol 566.19
    triethyl phosphate 929.83
    4-methyl-2-pentanol 530.14
    propionitrile 2165.18
    vinylene carbonate 3170.47
    1,1,2-trichlorotrifluoroethane 2700.93
    DMS 1532.57
    cumene 641.59
    2-octanol 684.65
    2-hexanone 2274.51
    octyl acetate 1176.22
    limonene 2130.29
    1,2-dimethoxyethane 3264.89
    ethyl orthosilicate 897.79
    tributyl phosphate 792.28
    diacetone alcohol 1663.03
    N,N-dimethylaniline 1187.87
    acrylonitrile 2529.83
    aniline 2323.93
    1,3-propanediol 645.32
    bromobenzene 5327.56
    dibromomethane 5058.74
    1,1,2,2-tetrachloroethane 6540.0
    2-methyl-cyclohexyl acetate 1755.75
    tetrabutyl urea 1154.19
    diisobutyl methanol 906.59
    2-phenylethanol 1487.63
    styrene 1795.35
    dioctyl adipate 1256.95
    dimethyl sulfate 1431.03
    ethyl butyrate 2597.63
    methyl lactate 659.52
    butyl lactate 1108.96
    diethyl carbonate 1470.55
    propanediol butyl ether 887.38
    triethyl orthoformate 1687.27
    p-tert-butyltoluene 1082.19
    methyl 4-tert-butylbenzoate 1370.93
    morpholine 5950.74
    tert-butylamine 1003.73
    n-dodecanol 461.19
    dimethoxymethane 2654.78
    ethylene carbonate 2871.91
    cyrene 1159.97
    2-ethoxyethyl acetate 2248.02
    2-ethylhexyl acetate 2777.59
    1,2,4-trichlorobenzene 3361.03
    4-methylpyridine 6916.87
    dibutyl ether 2274.84
    2,6-dimethyl-4-heptanol 906.59
    DEF 3690.39
    dimethyl isosorbide 2570.19
    tetrachloroethylene 4127.4
    eugenol 1117.31
    triacetin 1656.51
    span 80 1201.09
    1,4-butanediol 271.5
    1,1-dichloroethane 5170.46
    2-methyl-1-pentanol 679.87
    methyl formate 1436.8
    2-methyl-1-butanol 972.66
    n-decane 398.96
    butyronitrile 2660.1
    3,7-dimethyl-1-octanol 918.66
    1-chlorooctane 1210.52
    1-chlorotetradecane 487.92
    n-nonane 449.85
    undecane 269.53
    tert-butylcyclohexane 389.99
    cyclooctane 763.72
    cyclopentanol 2328.02
    tetrahydropyran 7943.25
    tert-amyl methyl ether 1727.67
    2,5,8-trioxanonane 1841.78
    1-hexene 1249.87
    2-isopropoxyethanol 765.65
    2,2,2-trifluoroethanol 390.67
    methyl butyrate 2423.19

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction