Ethanol, 2,2',2''-nitrilotris-, sulfate (salt)

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  • Identifiers

    CAS number
    7376-31-0

    Molecular formula
    C6H17NO7S

    SMILES
    C(CO)N(CCO)CCO.OS(=O)(=O)O

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 49.91%
    Sweet 49.29%
    Odorless 44.32%
    Alcoholic 31.06%
    Oily 20.31%
    Savory 15.1%
    Ripe 14.9%
    Cooling 14.84%
    Fresh 14.46%
    Solvent 14.11%

     

    Flavor
    Odorless 62.03%
    Sweet 36.4%
    Sweet-like 28.18%
    Mild 27.55%
    Bitter 26.57%
    Sulfurous 25.07%
    Very slight 22.83%
    Soup 21.25%
    Cauliflower 21.22%
    Bland 20.36%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.11 (neutral)

    Molecular weight
    247.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    347°C

    Flash point

    • 179.84 ˚C est.

  • Synonyms

    • Triethanolamine sulfate
    • 7376-31-0
    • Ethanol, 2,2',2''-nitrilotris-, sulfate (salt)
    • MV1V89M17O
    • RefChem:921213
    • DTXSID5049443
    • 230-934-6
    • 244-221-2
    • 21121-22-2
    • TEA-Sulfate
    • 20261-61-4
    • Bis[tris(hydroxyethyl)ammonium] sulphate
    • Ethanol, 2,2',2''-nitrilotris-, sulfate (2:1) (salt)
    • 2-[bis(2-hydroxyethyl)amino]ethanol;sulfuric acid
    • ETHANOL, 2,2',2''-NITRILOTRIS-, SULFATE (1:1) (SALT)
    • Triethanolamine sulphate (1:1)
    • Bis(tris(hydroxyethyl)ammonium) sulphate
    • triethanolammonium sulfate
    • UNII-MV1V89M17O
    • SCHEMBL248272
    • Ethanol, 2,2',2''-nitrilotris-, sulfate (2:1)
    • TRIETHANOLAMINE BISULFATE
    • RZRILSWMGXWSJY-UHFFFAOYSA-N
    • DTXSID801367429
    • EINECS 230-934-6
    • EINECS 244-221-2
    • TRIETHANOLAMINE SULFATE (1:1)
    • 2,2',2''-Nitrilotris(ethanol) sulfate (salt)
    • Ethanol, 2,2',2''-nitrilotris-, sulfate (1:?)
    • Q27284240
    • ETHANOL, 2,2',2''-NITRILOTRI-, SULFATE (SALT)
    • ETHANOL, 2,2',2''-NITRILOTRIS-, SULFATE (1:1)
    • ETHANOL, 2,2',2''-NITRILOTRI-, SULFATE (1:1) (SALT)
    • 90583-33-8
    • 7376-31-0

  • Applications

    Ethanol, 2,2',2''-nitrilotris-, sulfate (salt) (CAS 7376-31-0) is the sulfate salt of triethanolamine. In practice, it is used as a buffering agent and pH adjuster in cosmetics and personal care formulations (creams, cleansers, shampoos); as a stabilizer and neutralizing component in pharmaceutical formulations; as an intermediate or reagent in organic synthesis and in polymer-related processes such as polyurethane production and coatings; as an additive to control alkalinity and stabilize systems in paints, inks, and coatings; in industrial cleaning and metal-processing solutions as a pH modifier and chelating/complexing aid to improve cleaning performance; and can serve as a stabilizer, complexing agent, or catalyst in various polymer manufacturing processes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.36
    methanol 97.84
    isopropanol 5.94
    water 387.79
    ethyl acetate 2.26
    n-propanol 15.39
    acetone 1.27
    n-butanol 7.83
    acetonitrile 2.84
    DMF 48.79
    toluene 0.29
    isobutanol 6.13
    1,4-dioxane 10.01
    methyl acetate 2.69
    THF 9.43
    2-butanone 1.55
    n-pentanol 3.38
    sec-butanol 5.39
    n-hexane 0.22
    ethylene glycol 146.34
    NMP 118.11
    cyclohexane 0.81
    DMSO 95.5
    n-butyl acetate 2.02
    n-octanol 2.51
    chloroform 4.56
    n-propyl acetate 1.44
    acetic acid 77.67
    dichloromethane 7.09
    cyclohexanone 8.44
    propylene glycol 58.34
    isopropyl acetate 0.9
    DMAc 35.93
    2-ethoxyethanol 18.22
    isopentanol 2.7
    n-heptane 0.71
    ethyl formate 6.37
    1,2-dichloroethane 3.91
    n-hexanol 4.62
    2-methoxyethanol 54.84
    isobutyl acetate 0.82
    tetrachloromethane 1.76
    n-pentyl acetate 1.61
    transcutol 19.89
    n-heptanol 3.36
    ethylbenzene 0.3
    MIBK 0.49
    2-propoxyethanol 18.09
    tert-butanol 3.75
    MTBE 0.73
    2-butoxyethanol 10.65
    propionic acid 37.69
    o-xylene 0.71
    formic acid 308.35
    diethyl ether 1.04
    m-xylene 0.39
    p-xylene 0.42
    chlorobenzene 0.95
    dimethyl carbonate 2.47
    n-octane 0.28
    formamide 162.1
    cyclopentanone 10.42
    2-pentanone 0.91
    anisole 0.81
    cyclopentyl methyl ether 3.03
    gamma-butyrolactone 33.43
    1-methoxy-2-propanol 18.77
    pyridine 4.92
    3-pentanone 1.31
    furfural 38.36
    n-dodecane 0.19
    diethylene glycol 42.12
    diisopropyl ether 0.29
    tert-amyl alcohol 4.1
    acetylacetone 1.62
    n-hexadecane 0.21
    acetophenone 1.91
    methyl propionate 3.89
    isopentyl acetate 1.46
    trichloroethylene 5.51
    n-nonanol 2.36
    cyclohexanol 8.8
    benzyl alcohol 3.58
    2-ethylhexanol 2.46
    isooctanol 2.29
    dipropyl ether 1.82
    1,2-dichlorobenzene 2.07
    ethyl lactate 6.21
    propylene carbonate 15.05
    n-methylformamide 49.87
    2-pentanol 2.15
    n-pentane 0.31
    1-propoxy-2-propanol 9.56
    1-methoxy-2-propyl acetate 3.82
    2-(2-methoxypropoxy) propanol 8.58
    mesitylene 0.42
    ε-caprolactone 14.95
    p-cymene 1.0
    epichlorohydrin 11.02
    1,1,1-trichloroethane 1.31
    2-aminoethanol 102.48
    morpholine-4-carbaldehyde 66.78
    sulfolane 87.55
    2,2,4-trimethylpentane 0.23
    2-methyltetrahydrofuran 4.75
    n-hexyl acetate 2.13
    isooctane 0.1
    2-(2-butoxyethoxy)ethanol 10.81
    sec-butyl acetate 0.75
    tert-butyl acetate 0.91
    decalin 0.34
    glycerin 146.15
    diglyme 15.28
    acrylic acid 58.57
    isopropyl myristate 0.91
    n-butyric acid 18.68
    acetyl acetate 2.0
    di(2-ethylhexyl) phthalate 3.13
    ethyl propionate 1.74
    nitromethane 30.74
    1,2-diethoxyethane 2.1
    benzonitrile 2.62
    trioctyl phosphate 2.42
    1-bromopropane 1.26
    gamma-valerolactone 31.3
    n-decanol 1.73
    triethyl phosphate 3.6
    4-methyl-2-pentanol 0.87
    propionitrile 3.07
    vinylene carbonate 16.46
    1,1,2-trichlorotrifluoroethane 49.7
    DMS 3.81
    cumene 0.41
    2-octanol 1.57
    2-hexanone 0.79
    octyl acetate 1.48
    limonene 1.47
    1,2-dimethoxyethane 8.79
    ethyl orthosilicate 2.97
    tributyl phosphate 2.49
    diacetone alcohol 3.03
    N,N-dimethylaniline 1.48
    acrylonitrile 6.55
    aniline 2.55
    1,3-propanediol 53.12
    bromobenzene 0.61
    dibromomethane 3.46
    1,1,2,2-tetrachloroethane 6.44
    2-methyl-cyclohexyl acetate 2.78
    tetrabutyl urea 4.17
    diisobutyl methanol 1.31
    2-phenylethanol 3.69
    styrene 0.3
    dioctyl adipate 2.52
    dimethyl sulfate 11.09
    ethyl butyrate 2.19
    methyl lactate 13.96
    butyl lactate 5.52
    diethyl carbonate 2.12
    propanediol butyl ether 12.38
    triethyl orthoformate 2.86
    p-tert-butyltoluene 0.98
    methyl 4-tert-butylbenzoate 4.88
    morpholine 18.45
    tert-butylamine 1.88
    n-dodecanol 1.34
    dimethoxymethane 6.36
    ethylene carbonate 11.81
    cyrene 20.59
    2-ethoxyethyl acetate 2.73
    2-ethylhexyl acetate 1.46
    1,2,4-trichlorobenzene 2.99
    4-methylpyridine 2.41
    dibutyl ether 1.01
    2,6-dimethyl-4-heptanol 1.31
    DEF 8.36
    dimethyl isosorbide 14.91
    tetrachloroethylene 6.85
    eugenol 7.34
    triacetin 4.75
    span 80 11.43
    1,4-butanediol 21.33
    1,1-dichloroethane 1.16
    2-methyl-1-pentanol 1.95
    methyl formate 20.48
    2-methyl-1-butanol 4.24
    n-decane 0.29
    butyronitrile 2.26
    3,7-dimethyl-1-octanol 1.8
    1-chlorooctane 0.79
    1-chlorotetradecane 0.41
    n-nonane 0.28
    undecane 0.22
    tert-butylcyclohexane 0.23
    cyclooctane 0.35
    cyclopentanol 14.78
    tetrahydropyran 3.97
    tert-amyl methyl ether 1.07
    2,5,8-trioxanonane 13.66
    1-hexene 0.37
    2-isopropoxyethanol 6.2
    2,2,2-trifluoroethanol 51.67
    methyl butyrate 2.75

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction