Eriocitrin

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  • Identifiers

    CAS number
    13463-28-0

    Molecular formula
    C27H32O15

    SMILES
    C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 77.25%
    Vanilla 31.08%
    Sweet 26.42%
    Phenolic 22.9%
    Milky 20.86%
    Savory 20.56%
    Smoky 18.65%
    Burnt 18.65%
    Spicy 18.14%
    Creamy 17.93%

     

    Flavor
    Bitter 71.72%
    Odorless 33.12%
    Bland 33.06%
    Sweet-like 28.51%
    Cedarleaf 20.33%
    Very mild 20.07%
    Parsley 19.3%
    Eugenol 19.27%
    Very slight 19.24%
    Cauliflower 18.97%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.4

    pKa est.
    7.49 (neutral)

    Molecular weight
    596.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    4967°C

    Flash point

    • 272.13 ˚C est.

  • Synonyms

    • Eriocitrin
    • 13463-28-0
    • Eriodictioside
    • Eriodictyol-7-O-rutinoside
    • Eriodictyol 7-O-rutinoside
    • AS293HR5XQ
    • Eriodictyol 7-O-beta-rutinoside
    • CHEBI:28709
    • DTXSID60864408
    • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
    • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
    • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl)oxan-2-yl)oxy-2,3-dihydrochromen-4-one
    • RefChem:137630
    • GlyTouCan:G24470VQ
    • DTXCID701526915
    • G24470VQ
    • 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (2S)-
    • 236-668-7
    • (S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
    • 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (2S)-
    • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one
    • Eriocitrin (Mixture of Diastereomers)
    • UNII-AS293HR5XQ
    • MFCD28016053
    • (S)-3',4',5,7-Tetrahydroxyflavanone-7-[6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside]
    • EINECS 236-668-7
    • Eriocitrin (Standard)
    • Eriodictyol-7-rutinoside
    • ERIOCITRIN [WHO-DD]
    • SCHEMBL750974
    • Eriocitrin, analytical standard
    • orb1300258
    • CHEMBL2165586
    • SCHEMBL30205826
    • HY-N0636R
    • Eriocitrin, >=98.0% (HPLC)
    • EX-A6774
    • HY-N0636
    • BDBM50462417
    • s9211
    • AKOS030573687
    • CCG-208387
    • EBC-616273
    • FE65603
    • NCGC00163549-01
    • (S)-7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one
    • 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (S)-
    • AS-75208
    • CS-0009665
    • C09732
    • SR-05000002278
    • Eriocitrin, primary pharmaceutical reference standard
    • SR-05000002278-2
    • Q13567664
    • Glucopyranoside, eriodictyol-7 6-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-
    • (2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-1-benzopyran-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
    • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chroman-4-one
    • (2S)-7-[[6-O-(6-Deoxy-|A-L-mannopyranosyl)-|A-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one
    • 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (2S)-
    • Flavanone, 3',4',5,7-tetrahydroxy-, 7-(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside)
    • 13463-28-0

  • Applications

    Eriocitrin (CAS 13463-28-0) is a citrus-derived flavonoid glycoside. In industry, it is commonly evaluated as a natural antioxidant and formulation stabilizer for cosmetics and personal care products, helping protect lipids and other sensitive ingredients from oxidation. It is also investigated as a functional ingredient in food processing and dietary supplements to enhance antioxidant content and product stability. In pharmaceutical and chemical research, Eriocitrin may be used as an intermediate or starting material for synthesis and for exploration of bioactivity. In plant and agricultural research, it is studied for potential roles in plant physiology and defense, making it of interest as a marker compound in relevant studies.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.9
    methanol 10.45
    isopropanol 0.24
    water 0.03
    ethyl acetate 0.34
    n-propanol 1.58
    acetone 0.68
    n-butanol 1.38
    acetonitrile 0.22
    DMF 23.11
    toluene 0.06
    isobutanol 0.39
    1,4-dioxane 3.58
    methyl acetate 0.54
    THF 5.3
    2-butanone 1.04
    n-pentanol 0.31
    sec-butanol 0.48
    n-hexane 0.0
    ethylene glycol 5.78
    NMP 16.93
    cyclohexane 0.0
    DMSO 34.96
    n-butyl acetate 0.09
    n-octanol 0.4
    chloroform 0.12
    n-propyl acetate 0.11
    acetic acid 4.94
    dichloromethane 0.16
    cyclohexanone 1.65
    propylene glycol 8.08
    isopropyl acetate 0.14
    DMAc 16.82
    2-ethoxyethanol 8.52
    isopentanol 0.41
    n-heptane 0.01
    ethyl formate 1.05
    1,2-dichloroethane 0.15
    n-hexanol 0.13
    2-methoxyethanol 37.35
    isobutyl acetate 0.04
    tetrachloromethane 0.02
    n-pentyl acetate 0.3
    transcutol 13.18
    n-heptanol 0.37
    ethylbenzene 0.01
    MIBK 0.19
    2-propoxyethanol 4.12
    tert-butanol 0.15
    MTBE 0.09
    2-butoxyethanol 3.67
    propionic acid 1.51
    o-xylene 0.04
    formic acid 18.87
    diethyl ether 0.23
    m-xylene 0.03
    p-xylene 0.01
    chlorobenzene 0.03
    dimethyl carbonate 0.94
    n-octane 0.0
    formamide 13.4
    cyclopentanone 3.23
    2-pentanone 0.68
    anisole 0.14
    cyclopentyl methyl ether 0.49
    gamma-butyrolactone 4.05
    1-methoxy-2-propanol 11.98
    pyridine 1.14
    3-pentanone 0.43
    furfural 5.74
    n-dodecane 0.0
    diethylene glycol 7.86
    diisopropyl ether 0.02
    tert-amyl alcohol 0.24
    acetylacetone 1.17
    n-hexadecane 0.01
    acetophenone 0.2
    methyl propionate 0.85
    isopentyl acetate 0.07
    trichloroethylene 0.31
    n-nonanol 0.41
    cyclohexanol 0.37
    benzyl alcohol 0.38
    2-ethylhexanol 0.06
    isooctanol 0.19
    dipropyl ether 0.16
    1,2-dichlorobenzene 0.03
    ethyl lactate 0.68
    propylene carbonate 0.8
    n-methylformamide 10.83
    2-pentanol 0.23
    n-pentane 0.0
    1-propoxy-2-propanol 1.8
    1-methoxy-2-propyl acetate 0.64
    2-(2-methoxypropoxy) propanol 3.07
    mesitylene 0.01
    ε-caprolactone 1.85
    p-cymene 0.01
    epichlorohydrin 3.67
    1,1,1-trichloroethane 0.03
    2-aminoethanol 7.6
    morpholine-4-carbaldehyde 23.19
    sulfolane 12.53
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.84
    n-hexyl acetate 0.4
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 5.86
    sec-butyl acetate 0.06
    tert-butyl acetate 0.15
    decalin 0.0
    glycerin 30.22
    diglyme 9.95
    acrylic acid 2.97
    isopropyl myristate 0.1
    n-butyric acid 1.65
    acetyl acetate 0.2
    di(2-ethylhexyl) phthalate 0.26
    ethyl propionate 0.16
    nitromethane 8.12
    1,2-diethoxyethane 0.74
    benzonitrile 0.12
    trioctyl phosphate 0.2
    1-bromopropane 0.05
    gamma-valerolactone 20.52
    n-decanol 0.23
    triethyl phosphate 0.11
    4-methyl-2-pentanol 0.07
    propionitrile 0.26
    vinylene carbonate 1.02
    1,1,2-trichlorotrifluoroethane 9.81
    DMS 0.29
    cumene 0.01
    2-octanol 0.17
    2-hexanone 0.17
    octyl acetate 0.24
    limonene 0.03
    1,2-dimethoxyethane 6.0
    ethyl orthosilicate 0.11
    tributyl phosphate 0.15
    diacetone alcohol 1.24
    N,N-dimethylaniline 0.1
    acrylonitrile 0.61
    aniline 0.27
    1,3-propanediol 9.44
    bromobenzene 0.02
    dibromomethane 0.06
    1,1,2,2-tetrachloroethane 0.27
    2-methyl-cyclohexyl acetate 0.08
    tetrabutyl urea 0.4
    diisobutyl methanol 0.04
    2-phenylethanol 0.16
    styrene 0.02
    dioctyl adipate 0.32
    dimethyl sulfate 2.65
    ethyl butyrate 0.15
    methyl lactate 4.28
    butyl lactate 0.93
    diethyl carbonate 0.08
    propanediol butyl ether 5.64
    triethyl orthoformate 0.21
    p-tert-butyltoluene 0.01
    methyl 4-tert-butylbenzoate 0.74
    morpholine 6.66
    tert-butylamine 0.03
    n-dodecanol 0.13
    dimethoxymethane 8.61
    ethylene carbonate 0.63
    cyrene 4.31
    2-ethoxyethyl acetate 1.05
    2-ethylhexyl acetate 0.05
    1,2,4-trichlorobenzene 0.05
    4-methylpyridine 0.48
    dibutyl ether 0.17
    2,6-dimethyl-4-heptanol 0.04
    DEF 2.07
    dimethyl isosorbide 2.91
    tetrachloroethylene 0.19
    eugenol 1.14
    triacetin 0.93
    span 80 2.72
    1,4-butanediol 1.62
    1,1-dichloroethane 0.04
    2-methyl-1-pentanol 0.16
    methyl formate 7.11
    2-methyl-1-butanol 0.53
    n-decane 0.01
    butyronitrile 0.24
    3,7-dimethyl-1-octanol 0.14
    1-chlorooctane 0.05
    1-chlorotetradecane 0.02
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.63
    tetrahydropyran 0.77
    tert-amyl methyl ether 0.16
    2,5,8-trioxanonane 6.97
    1-hexene 0.01
    2-isopropoxyethanol 1.66
    2,2,2-trifluoroethanol 2.04
    methyl butyrate 0.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction