Erinacine C

Overview IFRA Request a quote

  • Identifiers

    CAS number
    156101-09-6

    Molecular formula
    C25H38O6

    SMILES
    CC(C)C1=C2[C@H]3CC=C([C@@H]4[C@@H]([C@@]3(CC[C@]2(CC1)C)C)O[C@H]5[C@H](O4)[C@H]([C@@H](CO5)O)O)CO

    Safety labels

  • Odor profile

    Fragrance
    Woody 54.17%
    Spicy 37.97%
    Amber 33.6%
    Odorless 33.06%
    Dry 29.25%
    Sandalwood 25.95%
    Balsamic 25.62%
    Mint 24.23%
    Musk 24.1%
    Cedar 23.68%

     

    Flavor
    Bitter 55.46%
    Fatty 31.78%
    Cedarleaf 23.06%
    Herbal 22.27%
    Sweet-like 22.16%
    Green tea 21.35%
    Soil 21.25%
    Earthy 21.0%
    Pleasant 20.94%
    Patchouli 20.94%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    5.04 (weak acid)

    Molecular weight
    434.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    691°C

    Flash point

    • 187.44 ˚C est.

  • Synonyms

    • Erinacine C
    • (1R,2R,5R,10R,14R,16R,17S,18R,21S)-13-(hydroxymethyl)-2,5-dimethyl-8-propan-2-yl-15,20,22-trioxapentacyclo[12.8.0.02,10.05,9.016,21]docosa-8,12-diene-17,18-diol
    • (1R,2R,5R,10R,14R,16R,17S,18R,21S)-13-(hydroxymethyl)-2,5-dimethyl-8-propan-2-yl-15,20,22-trioxapentacyclo(12.8.0.02,10.05,9.016,21)docosa-8,12-diene-17,18-diol
    • RefChem:921113
    • Erinacin C
    • 156101-09-6
    • RR9WB4ATX2
    • orb1942320
    • SCHEMBL21003630
    • CHEBI:187640
    • DTXSID901318487
    • HY-N11004
    • beta-D-Xylopyranose, 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-
    • (3bR,6aR,7aR,8S,9R,11aS,12aR,12bR,14aR)-6-(Hydroxymethyl)-12b,14a-dimethyl-3-(propan-2-yl)-1,2,3b,4,6a,7a,9,10,11a,12a,12b,13,14,14a-tetradecahydro-8H-indeno[4',5':6,7]cyclohepta[1,2-b]pyrano[3,2-e][1,4]dioxine-8,9-diol
    • 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-Decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-beta-D-xylopyranose
    • 156101-09-6

  • Applications

    Erinacine C, CAS 156101-09-6, is a natural diterpenoid isolated from Hericium erinaceus (lion’s mane). In practice, its use is largely limited to research contexts: as a lead/reference compound in natural product chemistry and medicinal chemistry; investigated for potential neurotrophic activity, including cellular induction of nerve growth factor (NGF); used as an analytical standard or tool in method development and metabolite profiling by LC-MS and related techniques; evaluated in cosmetics research as a bioactive diterpenoid with potential for skin-care formulation development; and may serve as a precursor or scaffold for derivative exploration in medicinal chemistry. Real-world product-level applications are limited and subject to regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 29.75
    methanol 53.12
    isopropanol 15.99
    water 0.8
    ethyl acetate 21.99
    n-propanol 26.87
    acetone 37.14
    n-butanol 20.89
    acetonitrile 15.64
    DMF 70.01
    toluene 11.49
    isobutanol 16.17
    1,4-dioxane 44.7
    methyl acetate 20.69
    THF 83.63
    2-butanone 27.02
    n-pentanol 17.88
    sec-butanol 8.58
    n-hexane 0.51
    ethylene glycol 14.65
    NMP 60.7
    cyclohexane 1.25
    DMSO 115.92
    n-butyl acetate 20.87
    n-octanol 13.3
    chloroform 49.46
    n-propyl acetate 17.79
    acetic acid 75.56
    dichloromethane 33.99
    cyclohexanone 51.68
    propylene glycol 14.02
    isopropyl acetate 19.14
    DMAc 72.54
    2-ethoxyethanol 55.93
    isopentanol 16.17
    n-heptane 0.89
    ethyl formate 22.67
    1,2-dichloroethane 23.48
    n-hexanol 19.97
    2-methoxyethanol 73.02
    isobutyl acetate 15.85
    tetrachloromethane 9.24
    n-pentyl acetate 30.42
    transcutol 104.36
    n-heptanol 21.27
    ethylbenzene 5.83
    MIBK 20.44
    2-propoxyethanol 68.53
    tert-butanol 12.71
    MTBE 7.62
    2-butoxyethanol 60.19
    propionic acid 28.55
    o-xylene 8.89
    formic acid 49.1
    diethyl ether 12.3
    m-xylene 10.17
    p-xylene 7.33
    chlorobenzene 17.67
    dimethyl carbonate 27.55
    n-octane 0.54
    formamide 53.97
    cyclopentanone 65.9
    2-pentanone 26.98
    anisole 16.23
    cyclopentyl methyl ether 25.16
    gamma-butyrolactone 66.91
    1-methoxy-2-propanol 52.7
    pyridine 39.66
    3-pentanone 20.04
    furfural 68.63
    n-dodecane 0.43
    diethylene glycol 63.52
    diisopropyl ether 4.43
    tert-amyl alcohol 8.65
    acetylacetone 40.76
    n-hexadecane 0.52
    acetophenone 27.39
    methyl propionate 26.0
    isopentyl acetate 23.14
    trichloroethylene 56.62
    n-nonanol 14.66
    cyclohexanol 14.76
    benzyl alcohol 26.68
    2-ethylhexanol 11.69
    isooctanol 17.43
    dipropyl ether 9.72
    1,2-dichlorobenzene 18.27
    ethyl lactate 24.41
    propylene carbonate 37.21
    n-methylformamide 48.56
    2-pentanol 8.77
    n-pentane 0.69
    1-propoxy-2-propanol 40.74
    1-methoxy-2-propyl acetate 42.9
    2-(2-methoxypropoxy) propanol 40.46
    mesitylene 6.23
    ε-caprolactone 46.87
    p-cymene 7.2
    epichlorohydrin 68.69
    1,1,1-trichloroethane 18.18
    2-aminoethanol 27.21
    morpholine-4-carbaldehyde 83.06
    sulfolane 90.41
    2,2,4-trimethylpentane 0.58
    2-methyltetrahydrofuran 23.99
    n-hexyl acetate 28.28
    isooctane 0.56
    2-(2-butoxyethoxy)ethanol 57.3
    sec-butyl acetate 12.48
    tert-butyl acetate 19.84
    decalin 0.98
    glycerin 34.68
    diglyme 83.78
    acrylic acid 35.99
    isopropyl myristate 10.76
    n-butyric acid 38.75
    acetyl acetate 26.56
    di(2-ethylhexyl) phthalate 21.43
    ethyl propionate 14.8
    nitromethane 75.29
    1,2-diethoxyethane 23.76
    benzonitrile 24.69
    trioctyl phosphate 16.24
    1-bromopropane 8.44
    gamma-valerolactone 107.48
    n-decanol 9.3
    triethyl phosphate 13.83
    4-methyl-2-pentanol 8.65
    propionitrile 15.15
    vinylene carbonate 44.42
    1,1,2-trichlorotrifluoroethane 80.27
    DMS 26.12
    cumene 5.05
    2-octanol 10.35
    2-hexanone 17.61
    octyl acetate 16.27
    limonene 7.89
    1,2-dimethoxyethane 49.96
    ethyl orthosilicate 12.85
    tributyl phosphate 14.31
    diacetone alcohol 32.24
    N,N-dimethylaniline 13.84
    acrylonitrile 25.33
    aniline 21.39
    1,3-propanediol 39.19
    bromobenzene 14.85
    dibromomethane 20.4
    1,1,2,2-tetrachloroethane 41.72
    2-methyl-cyclohexyl acetate 21.08
    tetrabutyl urea 19.1
    diisobutyl methanol 6.86
    2-phenylethanol 32.08
    styrene 6.44
    dioctyl adipate 20.6
    dimethyl sulfate 45.64
    ethyl butyrate 16.43
    methyl lactate 35.24
    butyl lactate 36.06
    diethyl carbonate 12.84
    propanediol butyl ether 47.82
    triethyl orthoformate 16.01
    p-tert-butyltoluene 6.65
    methyl 4-tert-butylbenzoate 40.35
    morpholine 51.82
    tert-butylamine 5.42
    n-dodecanol 5.88
    dimethoxymethane 62.75
    ethylene carbonate 38.92
    cyrene 56.54
    2-ethoxyethyl acetate 46.62
    2-ethylhexyl acetate 17.4
    1,2,4-trichlorobenzene 24.95
    4-methylpyridine 28.74
    dibutyl ether 6.88
    2,6-dimethyl-4-heptanol 6.86
    DEF 30.41
    dimethyl isosorbide 65.04
    tetrachloroethylene 35.03
    eugenol 43.28
    triacetin 41.24
    span 80 39.22
    1,4-butanediol 22.25
    1,1-dichloroethane 16.44
    2-methyl-1-pentanol 14.36
    methyl formate 38.59
    2-methyl-1-butanol 14.15
    n-decane 0.87
    butyronitrile 13.9
    3,7-dimethyl-1-octanol 11.37
    1-chlorooctane 4.51
    1-chlorotetradecane 1.71
    n-nonane 0.7
    undecane 0.58
    tert-butylcyclohexane 0.76
    cyclooctane 0.7
    cyclopentanol 17.25
    tetrahydropyran 26.34
    tert-amyl methyl ether 7.31
    2,5,8-trioxanonane 57.77
    1-hexene 2.19
    2-isopropoxyethanol 35.49
    2,2,2-trifluoroethanol 36.72
    methyl butyrate 19.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction