Epitestosterone, propionate

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  • Identifiers

    CAS number
    58769-88-3

    Molecular formula
    C22H32O3

    SMILES
    CCC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

  • Odor profile

    Fragrance
    Woody 79.8%
    Fruity 64.58%
    Cedar 45.39%
    Amber 40.1%
    Dry 36.82%
    Balsamic 33.33%
    Berry 30.79%
    Musk 30.14%
    Fresh 29.76%
    Tobacco 29.1%

     

    Flavor
    Bitter 37.45%
    Minty 28.34%
    Fruity 28.29%
    Herbal 26.46%
    Fruit 25.16%
    Spicy 24.06%
    Ripe apricot 22.31%
    Cedarleaf 22.26%
    Balsam 21.91%
    Red fruit 21.79%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.4

    pKa est.
    6.59 (neutral)

    Molecular weight
    344.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    455°C

    Flash point

    • 206.49 ˚C est.

  • Synonyms

    • 58769-88-3
    • ChemDiv1_020720
    • Epitestosterone, propionate
    • Agovirin;Androlon;Androteston
    • Oprea1_796838
    • CHEMBL297687
    • SCHEMBL18438820
    • HMS645N18
    • PDMMFKSKQVNJMI-UHFFFAOYSA-N
    • BCP23359
    • NSC98537
    • NSC-98537
    • AKOS001604287
    • AKOS021988029
    • CCG-248734
    • NCGC00249617-01
    • LS-14967
    • AA-504/07226014
    • 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylpropionate
    • 9A,11A-DIMETHYL-7-OXO-1H,2H,3H,3AH,3BH,4H,5H,7H,8H,9H,9AH,9BH,10H,11H,11AH-CYCLOPENTA[A]PHENANTHREN-1-YL PROPANOATE

  • Applications

    Epitestosterone, propionate (CAS 58769-88-3) is primarily used as a steroid ester intermediate in pharmaceutical synthesis, enabling production of epitestosterone derivatives through propionate esterification and subsequent hydrolysis steps. In industrial manufacturing, it functions as a building block in steroid chemistry workflows and as a research reference material for analytical method development and quality control. In pharmaceutical development, the propionate ester form may be evaluated as a prodrug to modulate release and pharmacokinetics in hormone-related formulations, subject to regulatory constraints. In analytical laboratories, it serves as a reference standard for hormone analysis and method validation, and it may appear in custom synthesis and contract manufacturing of steroid compounds.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 34.27
    methanol 31.41
    isopropanol 40.38
    water 0.39
    ethyl acetate 74.68
    n-propanol 44.64
    acetone 82.83
    n-butanol 50.93
    acetonitrile 44.28
    DMF 82.16
    toluene 198.62
    isobutanol 34.73
    1,4-dioxane 154.5
    methyl acetate 49.4
    THF 208.66
    2-butanone 76.15
    n-pentanol 25.26
    sec-butanol 16.63
    n-hexane 0.89
    ethylene glycol 5.48
    NMP 58.23
    cyclohexane 7.53
    DMSO 47.42
    n-butyl acetate 55.81
    n-octanol 10.85
    chloroform 329.49
    n-propyl acetate 46.68
    acetic acid 37.7
    dichloromethane 192.14
    cyclohexanone 142.47
    propylene glycol 6.75
    isopropyl acetate 77.07
    DMAc 90.92
    2-ethoxyethanol 51.76
    isopentanol 48.44
    n-heptane 0.8
    ethyl formate 33.22
    1,2-dichloroethane 97.37
    n-hexanol 33.3
    2-methoxyethanol 79.29
    isobutyl acetate 46.84
    tetrachloromethane 30.23
    n-pentyl acetate 42.99
    transcutol 174.84
    n-heptanol 20.24
    ethylbenzene 43.34
    MIBK 64.59
    2-propoxyethanol 105.42
    tert-butanol 32.79
    MTBE 21.3
    2-butoxyethanol 61.78
    propionic acid 28.45
    o-xylene 66.3
    formic acid 14.53
    diethyl ether 40.79
    m-xylene 86.07
    p-xylene 54.72
    chlorobenzene 126.39
    dimethyl carbonate 39.86
    n-octane 0.49
    formamide 28.17
    cyclopentanone 135.01
    2-pentanone 74.28
    anisole 80.27
    cyclopentyl methyl ether 69.14
    gamma-butyrolactone 119.87
    1-methoxy-2-propanol 78.22
    pyridine 192.51
    3-pentanone 60.5
    furfural 132.46
    n-dodecane 0.58
    diethylene glycol 69.72
    diisopropyl ether 13.83
    tert-amyl alcohol 13.67
    acetylacetone 113.36
    n-hexadecane 0.74
    acetophenone 80.27
    methyl propionate 55.67
    isopentyl acetate 68.47
    trichloroethylene 221.53
    n-nonanol 13.43
    cyclohexanol 42.1
    benzyl alcohol 75.86
    2-ethylhexanol 18.6
    isooctanol 18.58
    dipropyl ether 16.96
    1,2-dichlorobenzene 99.73
    ethyl lactate 28.74
    propylene carbonate 70.22
    n-methylformamide 37.59
    2-pentanol 22.89
    n-pentane 1.52
    1-propoxy-2-propanol 64.01
    1-methoxy-2-propyl acetate 93.99
    2-(2-methoxypropoxy) propanol 53.01
    mesitylene 41.26
    ε-caprolactone 105.28
    p-cymene 20.75
    epichlorohydrin 150.67
    1,1,1-trichloroethane 88.97
    2-aminoethanol 16.88
    morpholine-4-carbaldehyde 114.46
    sulfolane 90.03
    2,2,4-trimethylpentane 1.14
    2-methyltetrahydrofuran 66.29
    n-hexyl acetate 41.85
    isooctane 1.32
    2-(2-butoxyethoxy)ethanol 70.25
    sec-butyl acetate 42.23
    tert-butyl acetate 65.01
    decalin 3.35
    glycerin 17.4
    diglyme 130.76
    acrylic acid 27.29
    isopropyl myristate 19.24
    n-butyric acid 70.42
    acetyl acetate 70.72
    di(2-ethylhexyl) phthalate 31.74
    ethyl propionate 43.21
    nitromethane 69.08
    1,2-diethoxyethane 52.4
    benzonitrile 98.45
    trioctyl phosphate 18.17
    1-bromopropane 45.07
    gamma-valerolactone 209.28
    n-decanol 9.4
    triethyl phosphate 27.03
    4-methyl-2-pentanol 22.9
    propionitrile 62.9
    vinylene carbonate 88.36
    1,1,2-trichlorotrifluoroethane 80.14
    DMS 57.27
    cumene 24.46
    2-octanol 10.16
    2-hexanone 41.11
    octyl acetate 22.06
    limonene 18.38
    1,2-dimethoxyethane 87.16
    ethyl orthosilicate 26.99
    tributyl phosphate 19.67
    diacetone alcohol 59.67
    N,N-dimethylaniline 45.06
    acrylonitrile 71.65
    aniline 133.96
    1,3-propanediol 46.15
    bromobenzene 136.65
    dibromomethane 118.02
    1,1,2,2-tetrachloroethane 170.22
    2-methyl-cyclohexyl acetate 45.21
    tetrabutyl urea 26.23
    diisobutyl methanol 14.11
    2-phenylethanol 80.0
    styrene 51.54
    dioctyl adipate 33.0
    dimethyl sulfate 47.03
    ethyl butyrate 44.21
    methyl lactate 33.26
    butyl lactate 40.38
    diethyl carbonate 34.17
    propanediol butyl ether 36.71
    triethyl orthoformate 37.26
    p-tert-butyltoluene 18.63
    methyl 4-tert-butylbenzoate 63.86
    morpholine 133.21
    tert-butylamine 16.87
    n-dodecanol 6.82
    dimethoxymethane 106.72
    ethylene carbonate 78.71
    cyrene 61.52
    2-ethoxyethyl acetate 80.91
    2-ethylhexyl acetate 49.27
    1,2,4-trichlorobenzene 112.23
    4-methylpyridine 194.09
    dibutyl ether 11.57
    2,6-dimethyl-4-heptanol 14.11
    DEF 51.96
    dimethyl isosorbide 95.17
    tetrachloroethylene 112.94
    eugenol 68.7
    triacetin 63.86
    span 80 41.05
    1,4-butanediol 15.17
    1,1-dichloroethane 90.73
    2-methyl-1-pentanol 23.63
    methyl formate 28.79
    2-methyl-1-butanol 29.95
    n-decane 1.06
    butyronitrile 57.66
    3,7-dimethyl-1-octanol 15.4
    1-chlorooctane 6.58
    1-chlorotetradecane 2.78
    n-nonane 0.75
    undecane 0.76
    tert-butylcyclohexane 2.16
    cyclooctane 2.03
    cyclopentanol 32.22
    tetrahydropyran 118.74
    tert-amyl methyl ether 14.59
    2,5,8-trioxanonane 85.92
    1-hexene 5.92
    2-isopropoxyethanol 41.43
    2,2,2-trifluoroethanol 22.63
    methyl butyrate 49.94

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction