Epitestosterone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    481-30-1

    Molecular formula
    C19H28O2

    SMILES
    C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@H]2O)CCC4=CC(=O)CC[C@]34C

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Woody 78.5%
    Fruity 44.38%
    Cedar 44.06%
    Amber 40.44%
    Dry 36.38%
    Balsamic 34.34%
    Musk 33.35%
    Spicy 33.32%
    Sweet 33.11%
    Fresh 30.53%

     

    Flavor
    Bitter 39.94%
    Spicy 28.14%
    Minty 26.8%
    Soil 23.1%
    Beet 23.02%
    Herbal 23.01%
    Fresh 22.76%
    Camphor 22.44%
    Ripe apricot 22.17%
    Cedarleaf 22.11%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.52 (neutral)

    Molecular weight
    288.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    374°C

    Flash point

    • 189.71 ˚C est.

  • Synonyms

    • Epitestosterone
    • Isotestosterone
    • 481-30-1
    • cis-Testosterone
    • 17-Epitestosterone
    • epi-Testosterone
    • 17-alpha-Testosterone
    • 17-epi-Testosterone
    • 17alpha-Hydroxyandrost-4-en-3-one
    • 17alpha-Testosterone
    • 17.alpha.-Testosterone
    • NSC 26499
    • 17alpha-cis-Testosterone
    • Testosterone, cis-
    • 17-alpha-Hydroxyandrost-4-en-3-one
    • (17-alpha)-17-Hydroxyandrost-4-en-3-one
    • 17.alpha.-Hydroxyandrost-4-en-3-one
    • alpha epitestosterone
    • BRN 1915396
    • 17a-cis-Testosterone
    • DTXSID8022329
    • CHEBI:42534
    • UNII-48L726977Z
    • NSC-26499
    • (8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    • Androst-4-en-3-one, 17-hydroxy-, (17alpha)-
    • EPITESTOSTERONE [MI]
    • Androst-4-en-3-one, 17alpha-hydroxy-
    • Androst-4-en-3-one, 17.alpha.-hydroxy-
    • DTXCID002329
    • 48L726977Z
    • ANDROST-4-EN-3-ONE, 17-alpha-HYDROXY-
    • 4-Androsten-17.alpha.-ol-3-one
    • 17.ALPHA.-CIS-TESTOSTERONE
    • Androst-4-en-3-one, 17-hydroxy-, (17-alpha)-
    • Androst-4-en-3-one, 17-hydroxy-, (17.alpha.)-
    • (17alpha)-17-hydroxyandrost-4-en-3-one
    • 4-ANDROSTENE-17.ALPHA.-OL-3-ONE
    • ANDROST-4-EN-17.ALPHA.-OL-3-ONE
    • TESTOSTERONE IMPURITY C [EP IMPURITY]
    • 17-Hydroxyandrost-4-en-3-one, (17.alpha.)-
    • (10alpha,13alpha,14beta,17alpha)-17-Hydroxyandrost-4-En-3-One
    • TESTOSTERONE IMPURITY C (EP IMPURITY)
    • 17 alpha Testosterone
    • 17alpha-Hydroxyandrost-4-en-3-one (Epitestosterone)
    • NCGC00091018-01
    • (8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-3-one
    • BIDD:ER0485
    • SCHEMBL334193
    • CHEMBL196228
    • 4-Androsten-17alpha-ol-3-one
    • NSC26499
    • Tox21_111058
    • BDBM50410492
    • LMST02020051
    • MSK2266-100A
    • DB07768
    • FE22743
    • 4-ANDROSTENE-17ALPHA-OL-3-ONE
    • Androst-4-en-3-one, (17.alpha.)-
    • SMP2_000253
    • ANDROST-4-EN-17ALPHA-OL-3-ONE
    • NCGC00091018-02
    • CAS-481-30-1
    • Epitestosterone 1.0 mg/ml in Acetonitrile
    • DB-222500
    • NS00008414
    • 17-Hydroxyandrost-4-en-3-one, (17alpha)-
    • Androst-4-en-3-one, 17alpha-hydroxy-(8CI)
    • Q416852
    • Epitestosterone Solution in Acetonitrile, 100ug/mL
    • BRD-K25836724-001-01-6
    • (8R,10R,13S,17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

  • Applications

    Epitestosterone, CAS 481-30-1, is commonly used as an analytical standard for doping-control testing, serving as a reference material for quantification in LC-MS and GC-MS assays; it can be an intermediate in the synthesis of steroids and related androgenic compounds; it is used as a reference material for method development and calibration of steroid analyses; it is employed in pharmacokinetic and metabolic studies of androgens; it also serves as a research reagent in endocrinology and analytical chemistry.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 117.57
    methanol 133.09
    isopropanol 103.06
    water 1.14
    ethyl acetate 154.77
    n-propanol 111.19
    acetone 223.61
    n-butanol 120.91
    acetonitrile 84.27
    DMF 194.02
    toluene 273.57
    isobutanol 57.34
    1,4-dioxane 396.67
    methyl acetate 79.38
    THF 523.81
    2-butanone 107.48
    n-pentanol 18.51
    sec-butanol 17.89
    n-hexane 1.26
    ethylene glycol 16.16
    NMP 36.12
    cyclohexane 11.55
    DMSO 94.29
    n-butyl acetate 79.96
    n-octanol 11.41
    chloroform 360.57
    n-propyl acetate 51.11
    acetic acid 54.48
    dichloromethane 208.4
    cyclohexanone 173.04
    propylene glycol 13.46
    isopropyl acetate 149.91
    DMAc 88.42
    2-ethoxyethanol 68.97
    isopentanol 77.82
    n-heptane 1.8
    ethyl formate 60.29
    1,2-dichloroethane 138.29
    n-hexanol 41.86
    2-methoxyethanol 238.9
    isobutyl acetate 49.13
    tetrachloromethane 42.17
    n-pentyl acetate 47.64
    transcutol 440.24
    n-heptanol 23.68
    ethylbenzene 44.32
    MIBK 111.04
    2-propoxyethanol 161.92
    tert-butanol 83.18
    MTBE 57.48
    2-butoxyethanol 84.75
    propionic acid 37.96
    o-xylene 83.17
    formic acid 31.51
    diethyl ether 133.13
    m-xylene 133.32
    p-xylene 52.3
    chlorobenzene 130.94
    dimethyl carbonate 77.7
    n-octane 0.92
    formamide 75.47
    cyclopentanone 190.26
    2-pentanone 143.46
    anisole 108.66
    cyclopentyl methyl ether 126.55
    gamma-butyrolactone 167.57
    1-methoxy-2-propanol 186.24
    pyridine 269.51
    3-pentanone 86.09
    furfural 163.68
    n-dodecane 0.83
    diethylene glycol 125.18
    diisopropyl ether 33.12
    tert-amyl alcohol 17.19
    acetylacetone 227.24
    n-hexadecane 1.06
    acetophenone 80.53
    methyl propionate 100.3
    isopentyl acetate 93.9
    trichloroethylene 261.97
    n-nonanol 14.03
    cyclohexanol 51.96
    benzyl alcohol 67.82
    2-ethylhexanol 21.13
    isooctanol 21.62
    dipropyl ether 37.33
    1,2-dichlorobenzene 104.27
    ethyl lactate 32.76
    propylene carbonate 85.7
    n-methylformamide 110.28
    2-pentanol 34.98
    n-pentane 3.5
    1-propoxy-2-propanol 96.62
    1-methoxy-2-propyl acetate 167.86
    2-(2-methoxypropoxy) propanol 73.63
    mesitylene 63.36
    ε-caprolactone 115.91
    p-cymene 25.05
    epichlorohydrin 227.06
    1,1,1-trichloroethane 118.98
    2-aminoethanol 40.54
    morpholine-4-carbaldehyde 153.75
    sulfolane 101.09
    2,2,4-trimethylpentane 1.37
    2-methyltetrahydrofuran 97.23
    n-hexyl acetate 45.09
    isooctane 2.54
    2-(2-butoxyethoxy)ethanol 111.14
    sec-butyl acetate 49.09
    tert-butyl acetate 133.62
    decalin 3.6
    glycerin 39.64
    diglyme 251.95
    acrylic acid 37.09
    isopropyl myristate 23.03
    n-butyric acid 115.37
    acetyl acetate 124.26
    di(2-ethylhexyl) phthalate 30.22
    ethyl propionate 59.98
    nitromethane 141.93
    1,2-diethoxyethane 109.11
    benzonitrile 104.45
    trioctyl phosphate 18.98
    1-bromopropane 59.15
    gamma-valerolactone 299.15
    n-decanol 10.4
    triethyl phosphate 33.43
    4-methyl-2-pentanol 35.72
    propionitrile 114.24
    vinylene carbonate 114.53
    1,1,2-trichlorotrifluoroethane 109.82
    DMS 77.59
    cumene 25.39
    2-octanol 10.95
    2-hexanone 36.17
    octyl acetate 23.62
    limonene 22.38
    1,2-dimethoxyethane 168.14
    ethyl orthosilicate 33.22
    tributyl phosphate 21.77
    diacetone alcohol 101.48
    N,N-dimethylaniline 53.54
    acrylonitrile 141.53
    aniline 186.87
    1,3-propanediol 122.8
    bromobenzene 132.31
    dibromomethane 128.29
    1,1,2,2-tetrachloroethane 186.06
    2-methyl-cyclohexyl acetate 48.08
    tetrabutyl urea 27.67
    diisobutyl methanol 22.0
    2-phenylethanol 91.05
    styrene 54.26
    dioctyl adipate 35.13
    dimethyl sulfate 77.4
    ethyl butyrate 60.57
    methyl lactate 52.88
    butyl lactate 46.17
    diethyl carbonate 46.18
    propanediol butyl ether 51.19
    triethyl orthoformate 53.33
    p-tert-butyltoluene 26.43
    methyl 4-tert-butylbenzoate 75.9
    morpholine 309.31
    tert-butylamine 43.62
    n-dodecanol 7.59
    dimethoxymethane 343.46
    ethylene carbonate 107.01
    cyrene 58.49
    2-ethoxyethyl acetate 112.85
    2-ethylhexyl acetate 59.27
    1,2,4-trichlorobenzene 109.31
    4-methylpyridine 223.51
    dibutyl ether 18.51
    2,6-dimethyl-4-heptanol 22.0
    DEF 75.29
    dimethyl isosorbide 129.6
    tetrachloroethylene 132.55
    eugenol 79.67
    triacetin 76.6
    span 80 51.58
    1,4-butanediol 16.98
    1,1-dichloroethane 127.85
    2-methyl-1-pentanol 16.92
    methyl formate 74.37
    2-methyl-1-butanol 34.73
    n-decane 1.55
    butyronitrile 101.03
    3,7-dimethyl-1-octanol 18.35
    1-chlorooctane 7.58
    1-chlorotetradecane 3.2
    n-nonane 1.2
    undecane 1.09
    tert-butylcyclohexane 2.73
    cyclooctane 3.84
    cyclopentanol 39.02
    tetrahydropyran 258.45
    tert-amyl methyl ether 22.45
    2,5,8-trioxanonane 147.27
    1-hexene 6.15
    2-isopropoxyethanol 46.04
    2,2,2-trifluoroethanol 35.59
    methyl butyrate 60.08

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction