Epichlorohydrin

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  • Identifiers

    CAS number
    106-89-8

    Molecular formula
    C3H5ClO

    SMILES
    C1C(O1)CCl

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fishy 36.1%
    Odorless 29.01%
    Fruity 28.83%
    Oily 26.31%
    Cheesy 25.75%
    Buttery 24.23%
    Alcoholic 24.01%
    Caramellic 24.01%
    Sweet 23.81%
    Nutty 22.13%

     

    Flavor
    Sulfurous 50.29%
    Roasted 49.38%
    Meaty 37.77%
    Sulfury 30.71%
    Chicken 29.09%
    Onion 27.87%
    Fishy 27.86%
    Vegetable 26.89%
    Burnt 24.26%
    Cauliflower 23.95%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 0.08 [mmHg]. Odor Threshold High: 12.0 [mmHg]. Odor threshold from AIHA
    • Sensory perception studies indicate that mean threshold for odor recognition is approximately 10 ppm ... @ 25 ppm it is recognized by majority of persons.
    • Human Odor Perception: non perception 0.2 mg/cu m; perception 0.3 mg/cu m

  • Properties

    XLogP3-AA
    0.5

    pKa est.
    3.05 (weak acid)

    Molecular weight
    92.52 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -54.4 to -14.1 °F (EPA, 1998)
    • -25.6 °C
    • -57.2 °C
    • -48 °C
    • -54 °F

    Boiling point

    • 241.7 °F at 760 mmHg (EPA, 1998)
    • 117.9 °C
    • 116 °C
    • 242 °F

    Flash point

    • 30.45 ˚C est.
    • 93 °F (EPA, 1998)
    • 88 °F
    • 88 °F (31 °C) (Closed cup)
    • 31 °C c.c.
    • 93 °F

    Solubility expt.

    • 50 to 100 mg/mL at 72 °F (NTP, 1992)
    • Miscible with most organic solvents
    • Miscible with alcohol, ether, chloroform, trichloroethylene, carbon tetrachloride; immiscible with petroleum hydrocarbons.
    • In water, 6.59X10+4 mg/L at 25 °C
    • 65.9 mg/mL at 25 °C
    • Solubility in water, g/100ml at 20 °C: 6
    • 7%

  • Synonyms

    • EPICHLOROHYDRIN
    • 2-(Chloromethyl)oxirane
    • 106-89-8
    • Epichlorhydrin
    • 1-Chloro-2,3-epoxypropane
    • Oxirane, (chloromethyl)-
    • Epichlorhydrine
    • Glycidyl chloride
    • Chloromethyloxirane
    • 1,2-Epoxy-3-chloropropane
    • 2,3-Epoxypropyl chloride
    • Chloropropylene oxide
    • Epichloorhydrine
    • 3-Chloro-1,2-epoxypropane
    • Glycerol epichlorhydrin
    • Glycerol epichlorohydrin
    • 3-Chloropropylene oxide
    • (Chloromethyl)ethylene oxide
    • Epicloridrina
    • (CHLOROMETHYL)OXIRANE
    • Epichlorohydryna
    • Epichlorophydrin
    • SKEKhG
    • epi-Chlorohydrin
    • alpha-Epichlorohydrin
    • 3-Chloro-1,2-propylene oxide
    • 2-Chloromethyl-oxirane
    • 3-Chloropropene-1,2-oxide
    • (+/-)-Epichlorohydrin
    • Oxirane, 2-(chloromethyl)
    • epichlorohydrine
    • gamma-Chloropropylene oxide
    • 1-Cloro-2,3-epossipropano
    • Propane, 1-chloro-2,3-epoxy-
    • 1-Chlor-2,3-epoxy-propan
    • (RS)-3-chloro-1,2-epoxypropane
    • 1-Chloor-2,3-epoxy-propaan
    • Epoxypropyl chloride
    • Rcra waste number U041
    • DL-a-Epichlorohydrin
    • Caswell No. 424
    • (+/-)-2-(Chloromethyl)oxirane
    • Allyl chloride oxide
    • NSC 6747
    • HSDB 39
    • Epoxy-3-chloropropane
    • CCRIS 277
    • (chloromethyl)-Oxirane
    • Chloropropylene
    • .alpha.-Epichlorohydrin
    • Oxirane,(chloromethyl)-
    • NCI-C07001
    • EINECS 203-439-8
    • Alyl chloride oxide
    • Chloropropyl epoxide
    • .gamma.-Chloropropylene oxide
    • EPA Pesticide Chemical Code 097201
    • UNII-08OOR508C0
    • (DL)-.alpha.-Epichlorohydrin
    • BRN 0079785
    • DTXSID1020566
    • CHEBI:37144
    • AI3-03545
    • 08OOR508C0
    • NSC-6747
    • Chloro-1,2-epoxypropane
    • Chloro-2,3-epoxypropane
    • Chloropropene-1,2-oxide
    • 3-Chloro-propylene oxide
    • 2-(chloromethyl)-oxirane
    • MFCD00005132
    • (DL)-alpha-Epichlorohydrin
    • Chloro-1,2-propylene oxide
    • 1-chloro-2,3-epoxy-propane
    • 1-Chloro-2,3-epoxy propone
    • DTXCID50566
    • NSC6747
    • EC 203-439-8
    • (+/-)-1-Chloro-2,3-epoxypropane
    • 13403-37-7
    • ECH
    • NCGC00091792-01
    • Epichlorohydrin, >=99%
    • EPICHLOROHYDRIN (IARC)
    • EPICHLOROHYDRIN [IARC]
    • EPICHLOROHYDRIN (MART.)
    • EPICHLOROHYDRIN [MART.]
    • Epicloridrina [Italian]
    • Epichloorhydrine [Dutch]
    • Epichlorhydrine [French]
    • Epichlorohydryna [Polish]
    • CAS-106-89-8
    • 3-Chloropropyl epoxide
    • 2-Chloropropylene oxide
    • dl-alpha-epichlorohydrin
    • 5-17-01-00020 (Beilstein Handbook Reference)
    • UN2023
    • 1-Chlor-2,3-epoxy-propan [German]
    • RCRA waste no. U041
    • 1-Chloor-2,3-epoxy-propaan [Dutch]
    • 1-Cloro-2,3-epossipropano [Italian]
    • epichiorohydrin
    • (chloromethyl) Ethylene oxide
    • Epichlorohydrin, (+-)-Isomer
    • epi-chlorohydrine
    • a-Epichlorohydrin
    • Epichloro hydrine
    • (rs)-epichlorohydrin
    • (+) epichlorohydrin
    • (-) epichlorohydrin
    • 2-chloromethyloxirane
    • (?)-Epichlorohydrin
    • chloromethyl) Oxirane
    • (rac)-epichlorohydrin
    • racemic epichlorohydrin
    • (+-)-epichlorohydrin
    • a-Chloropropylene oxide
    • beta-epoxypropylchloride
    • racemic epichlorohydrine
    • Epichlorohydrin, 99%
    • Chloromethylethylene Oxide
    • 2-(chloromethyl) Oxirane
    • ALPHA-EPICHOROHYDRIN
    • bmse000722
    • (RS)-EPICHLORHYDRIN
    • WLN: T3OTJ B1G
    • CRUDE EPICHLOROHYDRIN
    • (RS)-(chloromethyl)oxirane

  • Applications

    Epichlorohydrin is a key intermediate in polymer and resin production, primarily used to make epoxy resins and glycidyl ethers. Epoxy resins derived from it are widely used in coatings and protective paints, adhesives, and electrical/electronic applications due to their cured network properties; glycidyl ethers are employed as monomers or reactive diluents for various polymer systems and coating formulations. It also serves as an intermediate for epoxy-based laminates and electrical insulating materials, and as a precursor for other industrial plastics and polymers. Its use is typically governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 243.45
    methanol 377.77
    isopropanol 134.39
    water 25.78
    ethyl acetate 72.84
    n-propanol 139.97
    acetone 269.45
    n-butanol 108.58
    acetonitrile 213.27
    DMF 419.16
    toluene 24.13
    isobutanol 86.99
    1,4-dioxane 199.94
    methyl acetate 127.13
    THF 216.11
    2-butanone 143.15
    n-pentanol 77.83
    sec-butanol 93.39
    n-hexane 4.88
    ethylene glycol 166.96
    NMP 297.11
    cyclohexane 14.23
    DMSO 514.31
    n-butyl acetate 63.43
    n-octanol 37.51
    chloroform 209.72
    n-propyl acetate 62.33
    acetic acid 505.38
    dichloromethane 208.9
    cyclohexanone 146.91
    propylene glycol 129.79
    isopropyl acetate 41.35
    DMAc 307.72
    2-ethoxyethanol 187.05
    isopentanol 77.32
    n-heptane 9.37
    ethyl formate 81.1
    1,2-dichloroethane 117.33
    n-hexanol 59.79
    2-methoxyethanol 301.4
    isobutyl acetate 39.5
    tetrachloromethane 35.18
    n-pentyl acetate 40.01
    transcutol 485.77
    n-heptanol 33.74
    ethylbenzene 14.19
    MIBK 47.83
    2-propoxyethanol 137.99
    tert-butanol 128.4
    MTBE 62.13
    2-butoxyethanol 88.69
    propionic acid 148.0
    o-xylene 23.77
    formic acid 323.95
    diethyl ether 67.85
    m-xylene 18.36
    p-xylene 23.52
    chlorobenzene 46.91
    dimethyl carbonate 38.92
    n-octane 3.39
    formamide 334.72
    cyclopentanone 186.57
    2-pentanone 81.44
    anisole 57.96
    cyclopentyl methyl ether 73.44
    gamma-butyrolactone 180.68
    1-methoxy-2-propanol 164.88
    pyridine 173.56
    3-pentanone 68.53
    furfural 222.99
    n-dodecane 3.21
    diethylene glycol 193.47
    diisopropyl ether 16.6
    tert-amyl alcohol 85.5
    acetylacetone 102.43
    n-hexadecane 3.51
    acetophenone 70.19
    methyl propionate 69.67
    isopentyl acetate 50.26
    trichloroethylene 235.75
    n-nonanol 33.39
    cyclohexanol 90.44
    benzyl alcohol 74.23
    2-ethylhexanol 39.72
    isooctanol 29.34
    dipropyl ether 44.07
    1,2-dichlorobenzene 47.31
    ethyl lactate 51.26
    propylene carbonate 84.75
    n-methylformamide 224.09
    2-pentanol 59.15
    n-pentane 7.25
    1-propoxy-2-propanol 101.2
    1-methoxy-2-propyl acetate 68.15
    2-(2-methoxypropoxy) propanol 112.62
    mesitylene 14.04
    ε-caprolactone 115.23
    p-cymene 20.32
    epichlorohydrin 189.6
    1,1,1-trichloroethane 87.83
    2-aminoethanol 199.15
    morpholine-4-carbaldehyde 304.51
    sulfolane 239.54
    2,2,4-trimethylpentane 5.33
    2-methyltetrahydrofuran 124.82
    n-hexyl acetate 54.18
    isooctane 3.72
    2-(2-butoxyethoxy)ethanol 144.51
    sec-butyl acetate 36.86
    tert-butyl acetate 45.43
    decalin 5.51
    glycerin 199.35
    diglyme 262.95
    acrylic acid 180.76
    isopropyl myristate 24.25
    n-butyric acid 123.16
    acetyl acetate 55.81
    di(2-ethylhexyl) phthalate 33.13
    ethyl propionate 44.78
    nitromethane 459.85
    1,2-diethoxyethane 98.68
    benzonitrile 79.08
    trioctyl phosphate 22.93
    1-bromopropane 51.39
    gamma-valerolactone 234.39
    n-decanol 25.87
    triethyl phosphate 33.05
    4-methyl-2-pentanol 33.02
    propionitrile 109.05
    vinylene carbonate 86.78
    1,1,2-trichlorotrifluoroethane 245.72
    DMS 51.68
    cumene 13.67
    2-octanol 23.09
    2-hexanone 67.43
    octyl acetate 32.46
    limonene 32.02
    1,2-dimethoxyethane 211.64
    ethyl orthosilicate 30.72
    tributyl phosphate 29.16
    diacetone alcohol 86.92
    N,N-dimethylaniline 47.56
    acrylonitrile 156.88
    aniline 72.83
    1,3-propanediol 174.94
    bromobenzene 36.15
    dibromomethane 119.76
    1,1,2,2-tetrachloroethane 172.35
    2-methyl-cyclohexyl acetate 48.18
    tetrabutyl urea 44.03
    diisobutyl methanol 27.28
    2-phenylethanol 62.22
    styrene 21.06
    dioctyl adipate 46.42
    dimethyl sulfate 73.91
    ethyl butyrate 52.74
    methyl lactate 68.47
    butyl lactate 47.74
    diethyl carbonate 38.73
    propanediol butyl ether 108.43
    triethyl orthoformate 42.95
    p-tert-butyltoluene 18.54
    methyl 4-tert-butylbenzoate 63.09
    morpholine 245.81
    tert-butylamine 69.23
    n-dodecanol 21.22
    dimethoxymethane 137.21
    ethylene carbonate 65.61
    cyrene 109.12
    2-ethoxyethyl acetate 66.63
    2-ethylhexyl acetate 40.87
    1,2,4-trichlorobenzene 70.34
    4-methylpyridine 109.42
    dibutyl ether 35.18
    2,6-dimethyl-4-heptanol 27.28
    DEF 124.46
    dimethyl isosorbide 134.27
    tetrachloroethylene 135.58
    eugenol 71.15
    triacetin 84.04
    span 80 89.77
    1,4-butanediol 94.98
    1,1-dichloroethane 98.41
    2-methyl-1-pentanol 60.28
    methyl formate 144.23
    2-methyl-1-butanol 74.56
    n-decane 4.78
    butyronitrile 84.8
    3,7-dimethyl-1-octanol 39.95
    1-chlorooctane 18.24
    1-chlorotetradecane 8.86
    n-nonane 4.44
    undecane 3.77
    tert-butylcyclohexane 5.21
    cyclooctane 4.28
    cyclopentanol 109.44
    tetrahydropyran 128.59
    tert-amyl methyl ether 47.13
    2,5,8-trioxanonane 198.45
    1-hexene 17.38
    2-isopropoxyethanol 115.12
    2,2,2-trifluoroethanol 168.92
    methyl butyrate 67.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction