Eosin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    17372-87-1

    Molecular formula
    C20H6Br4Na2O5

    SMILES
    C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)[O-])Br)Br)Br)C(=O)[O-].[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 55.68%
    Burnt 25.59%
    Phenolic 24.65%
    Fruity 23.66%
    Dry 20.37%
    Bitter 19.54%
    Musk 18.73%
    Savory 18.07%
    Powdery 17.53%
    Animal 17.51%

     

    Flavor
    Bitter 92.36%
    Odorless 35.37%
    Bland 20.32%
    Sweet-like 19.53%
    Nitrile 19.41%
    Very strong 19.27%
    Indole 18.8%
    Cedarleaf 18.15%
    Rotten 17.99%
    Orange flower 17.79%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.15 (weak acid)

    Molecular weight
    691.9 g/mol

    Melting point expt.

    • 572 °F (decomposes) (NTP, 1992)

    Flash point

    • 267.24 ˚C est.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)

  • Synonyms

    • Eosin
    • Acid red 87
    • 17372-87-1
    • Eosin yellowish
    • Eosine Yellowish
    • Eosine
    • Eosine G
    • Eosin YS
    • Sodium eosine
    • Bromo acid
    • Eosine Y
    • Bromofluorescein
    • Sodium eosinate
    • Bronze Bromo
    • Certiqual Eosine
    • Bromo Fluorescein
    • Eosine A
    • Eosine J
    • Eosine BS
    • Eosine DA
    • Eosine FA
    • Eosine GF
    • Eosine OJ
    • Eosine w/s
    • Eosine YB
    • Eosine YS
    • Toyo Eosine G
    • Bromo B
    • Eosine BPC
    • Eosine Salt Free
    • Phloxine Toner B
    • Pure Eosine YY
    • Bromo FL
    • Bromo TS
    • Bromo XX
    • Fenazo Eosine XG
    • Bromo JPS
    • Eosine 3G
    • Eosine 3Y
    • Eosine BS-SF
    • Bromo 4D
    • Bromo 4DC
    • Bromo 4DL
    • Eosine Lake Red Y
    • Hidacid White Bromo
    • Symuler Eosin Toner
    • Bromofluoresceic acid
    • Eosine K Salt Free
    • D and C Red No. 22
    • Disodium eosin
    • Eosin gelblich
    • Eosine DWC 73
    • Eosine S 13
    • Hidacid Boiling Bromo
    • Morning red
    • 1903 Yellow Pink
    • Tetrabromofluorescein D
    • Tetrabromofluorescein S
    • Aizen eosine GH
    • Dawn red
    • Eosine Yellowish-(YS)
    • Irgalite Bronze Red CL
    • Bromo X-100
    • Eosine K
    • Eosine GH
    • Eosin A
    • Eosin OJ
    • Hidacid Eosine Soda Salt
    • Eosine sodium salt
    • C.I. 45380
    • Cerven kysela 87
    • Hidacid Bromo acid regular
    • Hidacid Dibromo Fluorescein
    • Water Red 2
    • Tetrabromofluorescein soluble
    • Basacid Red 316
    • Phloxine Red 20-7600
    • Orient Water Red 2
    • Phlox Red Toner X-1354
    • Japan Red 103
    • Eosine Extra Yellowish
    • CI 45380 (Na salt)
    • Eosin Yellowish (YS)
    • Eosine Extra Conc. A. Export
    • Eosine S13 (bluish)
    • 11445 Red
    • 11731 Red
    • sodium eosin
    • Bromo X 100
    • Disodium eosine
    • Eosine disodium
    • Eosinum natrum
    • Japan Red 230-1
    • 2',4',5',7'-Tetrabromofluorescein disodium salt
    • TDQ283MPCW
    • Eosin sodium salt
    • Red No. 103
    • Red No. 230-1
    • Acid red 87 sodium
    • Aka223
    • CI 45380
    • Red no. 230(1)
    • Aka230(1)
    • Fluorescein, 2',4',5',7'-tetrabromo-, disodium salt
    • NSC-2087
    • disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
    • RefChem:920994
    • 241-409-6
    • DTXCID201473824
    • DTXSID0025234
    • Eosin Y
    • Red No. 223
    • Tetrabromofluorescein
    • C.I. Acid Red 87
    • 548-26-5
    • Bromoeosine
    • Eosin Y Disodium Salt
    • D&C Red No. 22
    • 2,4,5,7-Tetrabromo-3,6-fluorandiol
    • Sodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
    • Benzoic acid, 2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, disodium salt
    • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',4',5',7'-tetrabromo-3',6'-dihydroxy-, disodium salt
    • Eosin Y(water soluble)
    • Eosin Y, 96%
    • Eosin Y powder
    • eosin YS dye
    • Fenazo Eoxine XG
    • 17372-87-1

  • Applications

    Eosin (CAS 17372-87-1) is used primarily as a dye for histology and cytology staining, especially as part of the H&E staining procedure with hematoxylin; it is also a fluorescent dye used for fluorescence microscopy, and it serves as a colorant in coatings, inks, and textiles, with potential use as a pigment in plastics and polymers to color molded components.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.05
    methanol 0.76
    isopropanol 0.58
    water 0.0
    ethyl acetate 2.66
    n-propanol 1.18
    acetone 1.54
    n-butanol 0.85
    acetonitrile 0.82
    DMF 10.9
    toluene 3.02
    isobutanol 0.88
    1,4-dioxane 5.48
    methyl acetate 2.69
    THF 17.1
    2-butanone 2.95
    n-pentanol 1.02
    sec-butanol 0.91
    n-hexane 0.14
    ethylene glycol 0.76
    NMP 21.06
    cyclohexane 0.16
    DMSO 2.77
    n-butyl acetate 3.88
    n-octanol 1.5
    chloroform 3.49
    n-propyl acetate 3.24
    acetic acid 1.72
    dichloromethane 3.51
    cyclohexanone 5.97
    propylene glycol 0.73
    isopropyl acetate 2.51
    DMAc 14.98
    2-ethoxyethanol 3.56
    isopentanol 0.87
    n-heptane 0.32
    ethyl formate 1.67
    1,2-dichloroethane 2.07
    n-hexanol 1.43
    2-methoxyethanol 4.97
    isobutyl acetate 2.26
    tetrachloromethane 0.34
    n-pentyl acetate 4.74
    transcutol 11.76
    n-heptanol 1.55
    ethylbenzene 1.65
    MIBK 2.26
    2-propoxyethanol 6.98
    tert-butanol 0.57
    MTBE 1.45
    2-butoxyethanol 4.73
    propionic acid 1.65
    o-xylene 2.13
    formic acid 1.34
    diethyl ether 1.84
    m-xylene 2.12
    p-xylene 1.6
    chlorobenzene 1.61
    dimethyl carbonate 4.31
    n-octane 0.23
    formamide 2.45
    cyclopentanone 9.79
    2-pentanone 2.87
    anisole 3.61
    cyclopentyl methyl ether 7.57
    gamma-butyrolactone 11.32
    1-methoxy-2-propanol 4.45
    pyridine 8.25
    3-pentanone 2.88
    furfural 9.73
    n-dodecane 0.19
    diethylene glycol 4.49
    diisopropyl ether 0.83
    tert-amyl alcohol 1.03
    acetylacetone 4.0
    n-hexadecane 0.23
    acetophenone 4.73
    methyl propionate 4.44
    isopentyl acetate 3.45
    trichloroethylene 5.79
    n-nonanol 1.77
    cyclohexanol 1.61
    benzyl alcohol 3.2
    2-ethylhexanol 1.69
    isooctanol 1.46
    dipropyl ether 3.46
    1,2-dichlorobenzene 1.6
    ethyl lactate 2.67
    propylene carbonate 5.09
    n-methylformamide 3.75
    2-pentanol 0.79
    n-pentane 0.14
    1-propoxy-2-propanol 6.06
    1-methoxy-2-propyl acetate 8.05
    2-(2-methoxypropoxy) propanol 6.25
    mesitylene 1.12
    ε-caprolactone 7.77
    p-cymene 1.87
    epichlorohydrin 11.42
    1,1,1-trichloroethane 1.13
    2-aminoethanol 1.26
    morpholine-4-carbaldehyde 18.88
    sulfolane 12.16
    2,2,4-trimethylpentane 0.14
    2-methyltetrahydrofuran 7.24
    n-hexyl acetate 4.23
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 6.47
    sec-butyl acetate 2.58
    tert-butyl acetate 3.15
    decalin 0.2
    glycerin 1.78
    diglyme 10.37
    acrylic acid 2.24
    isopropyl myristate 2.3
    n-butyric acid 1.83
    acetyl acetate 1.93
    di(2-ethylhexyl) phthalate 2.85
    ethyl propionate 3.4
    nitromethane 3.32
    1,2-diethoxyethane 5.79
    benzonitrile 2.95
    trioctyl phosphate 1.72
    1-bromopropane 1.59
    gamma-valerolactone 15.59
    n-decanol 1.37
    triethyl phosphate 2.39
    4-methyl-2-pentanol 0.71
    propionitrile 1.39
    vinylene carbonate 4.87
    1,1,2-trichlorotrifluoroethane 9.49
    DMS 6.07
    cumene 1.16
    2-octanol 1.43
    2-hexanone 2.99
    octyl acetate 2.76
    limonene 2.27
    1,2-dimethoxyethane 6.74
    ethyl orthosilicate 2.38
    tributyl phosphate 1.85
    diacetone alcohol 3.79
    N,N-dimethylaniline 3.84
    acrylonitrile 2.41
    aniline 3.42
    1,3-propanediol 1.42
    bromobenzene 1.54
    dibromomethane 2.1
    1,1,2,2-tetrachloroethane 4.42
    2-methyl-cyclohexyl acetate 3.92
    tetrabutyl urea 3.69
    diisobutyl methanol 1.22
    2-phenylethanol 3.96
    styrene 1.72
    dioctyl adipate 3.4
    dimethyl sulfate 6.48
    ethyl butyrate 3.7
    methyl lactate 3.86
    butyl lactate 4.57
    diethyl carbonate 2.44
    propanediol butyl ether 3.71
    triethyl orthoformate 3.71
    p-tert-butyltoluene 1.84
    methyl 4-tert-butylbenzoate 6.47
    morpholine 8.37
    tert-butylamine 0.4
    n-dodecanol 1.06
    dimethoxymethane 8.74
    ethylene carbonate 3.52
    cyrene 7.95
    2-ethoxyethyl acetate 7.51
    2-ethylhexyl acetate 3.44
    1,2,4-trichlorobenzene 2.89
    4-methylpyridine 6.23
    dibutyl ether 2.47
    2,6-dimethyl-4-heptanol 1.22
    DEF 6.91
    dimethyl isosorbide 15.35
    tetrachloroethylene 2.99
    eugenol 6.68
    triacetin 5.76
    span 80 5.0
    1,4-butanediol 0.76
    1,1-dichloroethane 1.28
    2-methyl-1-pentanol 1.12
    methyl formate 3.01
    2-methyl-1-butanol 1.05
    n-decane 0.33
    butyronitrile 1.25
    3,7-dimethyl-1-octanol 1.59
    1-chlorooctane 1.11
    1-chlorotetradecane 0.53
    n-nonane 0.29
    undecane 0.25
    tert-butylcyclohexane 0.19
    cyclooctane 0.13
    cyclopentanol 2.29
    tetrahydropyran 4.04
    tert-amyl methyl ether 2.34
    2,5,8-trioxanonane 8.6
    1-hexene 0.7
    2-isopropoxyethanol 3.04
    2,2,2-trifluoroethanol 1.22
    methyl butyrate 3.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction