Ensulizole sodium

Overview IFRA Request a quote

  • Identifiers

    CAS number
    5997-53-5

    Molecular formula
    C13H9N2NaO3S

    SMILES
    C1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)S(=O)(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 72.95%
    Cooked 25.06%
    Burnt 22.26%
    Bitter 22.01%
    Roasted 18.27%
    Savory 17.83%
    Fruity 17.2%
    Grape 15.52%
    Sulfurous 15.03%
    Nutty 14.58%

     

    Flavor
    Bitter 90.24%
    Odorless 29.71%
    Nitrile 20.59%
    Very strong 18.78%
    Indole 18.38%
    Bread crust 18.25%
    Moth ball 18.24%
    Taco 18.01%
    Naphthelene 17.81%
    Roasted peanuts 17.75%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.52 (neutral)

    Molecular weight
    296.28 g/mol

    Flash point

    • 255.63 ˚C est.

  • Synonyms

    • Ensulizole sodium
    • 5997-53-5
    • Sodium phenylbenzimidazole sulfonate
    • 66LQ48A9BT
    • Sodium 2-phenyl-5-benzimidazolesulfonate
    • ENSULIZOLE SODIUM SALT
    • 2-Phenyl-1H-benzimidazole-5-sulfonic acid sodium salt
    • Phenylbenzimidazole sulfonic acid sodium salt
    • 1H-Benzimidazole-5-sulfonic acid, 2-phenyl-, monosodium salt
    • DTXSID601021879
    • ENSULIZOLE SODIUM [WHO-DD]
    • ENSULIZOLE SODIUM SALT [MI]
    • 5(or 6)-Benzimidazolesulfonic acid, 2-phenyl-, sodium salt
    • 1H-Benzimidazole-6-sulfonic acid, 2-phenyl-, sodium salt (1:1)
    • PHENYLBENZIMIDAZOLE-5-SULFONATE SODIUM
    • PHENYLBENZIMIDAZOLE-5-SULPHONATE SODIUM
    • 2-PHENYL-5-BENZIMIDAZOLSULFONATE SODIUM
    • SODIUM 2-PHENYL-1H-BENZYLIMIDAZOLE-5-SULFONATE
    • 2-PHENYL-5-BENZIMIDAZOLSULFONATE SODIUM [WHO-DD]
    • RefChem:590857
    • DTXCID301506816
    • SODIUM PHENYLBENZIMIDAZOLE SULFONATE [INCI]
    • 611-922-3
    • sodium;2-phenyl-3H-benzimidazole-5-sulfonate
    • 2-Phenylbenzimidazole-5-sulfonic acid sodium salt
    • Sodium 2-phenyl-1H-benzo[d]imidazole-5-sulfonate
    • UNII-66LQ48A9BT
    • SCHEMBL3173641
    • SCHEMBL3173657
    • JNUBZSFXMKCDFD-UHFFFAOYSA-M
    • Q27264002
    • 5997-53-5

  • Applications

    Ensulizole sodium (CAS 5997-53-5) is the sodium salt of the UV filter ensulizole, commonly used as a UVB absorber in cosmetics and personal care products. Its water solubility allows incorporation into aqueous formulations such as gels, lotions, and water-based sunscreens. Beyond cosmetics, it may be considered as a UV-stabilizing additive for water-based coatings and inks, helping to mitigate UV-driven degradation. It can be evaluated for use in polymer formulations to improve UV resistance, and in textile applications to protect fibers from UV exposure. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.59
    methanol 8.15
    isopropanol 3.97
    water 0.04
    ethyl acetate 6.9
    n-propanol 6.95
    acetone 18.32
    n-butanol 5.12
    acetonitrile 3.82
    DMF 149.57
    toluene 0.18
    isobutanol 2.92
    1,4-dioxane 11.14
    methyl acetate 12.19
    THF 35.31
    2-butanone 32.24
    n-pentanol 3.7
    sec-butanol 8.88
    n-hexane 0.0
    ethylene glycol 6.13
    NMP 15.37
    cyclohexane 0.01
    DMSO 25.55
    n-butyl acetate 5.13
    n-octanol 2.4
    chloroform 0.32
    n-propyl acetate 5.95
    acetic acid 9.33
    dichloromethane 0.45
    cyclohexanone 13.27
    propylene glycol 11.73
    isopropyl acetate 5.19
    DMAc 131.73
    2-ethoxyethanol 33.34
    isopentanol 4.03
    n-heptane 0.02
    ethyl formate 7.21
    1,2-dichloroethane 0.55
    n-hexanol 3.19
    2-methoxyethanol 81.38
    isobutyl acetate 2.23
    tetrachloromethane 0.02
    n-pentyl acetate 7.17
    transcutol 83.89
    n-heptanol 3.61
    ethylbenzene 0.18
    MIBK 5.59
    2-propoxyethanol 27.96
    tert-butanol 3.43
    MTBE 1.99
    2-butoxyethanol 20.91
    propionic acid 7.72
    o-xylene 0.2
    formic acid 9.96
    diethyl ether 1.74
    m-xylene 0.15
    p-xylene 0.27
    chlorobenzene 0.28
    dimethyl carbonate 7.2
    n-octane 0.02
    formamide 35.13
    cyclopentanone 25.39
    2-pentanone 13.03
    anisole 3.45
    cyclopentyl methyl ether 2.22
    gamma-butyrolactone 21.46
    1-methoxy-2-propanol 55.54
    pyridine 7.97
    3-pentanone 6.61
    furfural 17.96
    n-dodecane 0.05
    diethylene glycol 28.01
    diisopropyl ether 0.3
    tert-amyl alcohol 6.15
    acetylacetone 21.17
    n-hexadecane 0.05
    acetophenone 5.98
    methyl propionate 9.33
    isopentyl acetate 4.61
    trichloroethylene 1.69
    n-nonanol 2.91
    cyclohexanol 2.25
    benzyl alcohol 5.14
    2-ethylhexanol 1.79
    isooctanol 2.74
    dipropyl ether 1.53
    1,2-dichlorobenzene 0.37
    ethyl lactate 8.58
    propylene carbonate 7.18
    n-methylformamide 36.83
    2-pentanol 3.01
    n-pentane 0.01
    1-propoxy-2-propanol 17.89
    1-methoxy-2-propyl acetate 11.99
    2-(2-methoxypropoxy) propanol 22.09
    mesitylene 0.11
    ε-caprolactone 13.08
    p-cymene 0.35
    epichlorohydrin 15.83
    1,1,1-trichloroethane 0.17
    2-aminoethanol 13.27
    morpholine-4-carbaldehyde 40.94
    sulfolane 13.61
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 7.38
    n-hexyl acetate 6.69
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 32.84
    sec-butyl acetate 4.01
    tert-butyl acetate 5.52
    decalin 0.01
    glycerin 28.62
    diglyme 47.29
    acrylic acid 7.82
    isopropyl myristate 3.07
    n-butyric acid 9.26
    acetyl acetate 3.46
    di(2-ethylhexyl) phthalate 4.21
    ethyl propionate 5.14
    nitromethane 32.82
    1,2-diethoxyethane 12.18
    benzonitrile 3.4
    trioctyl phosphate 2.76
    1-bromopropane 0.19
    gamma-valerolactone 49.48
    n-decanol 2.33
    triethyl phosphate 2.58
    4-methyl-2-pentanol 1.55
    propionitrile 4.17
    vinylene carbonate 6.43
    1,1,2-trichlorotrifluoroethane 15.55
    DMS 6.21
    cumene 0.16
    2-octanol 2.54
    2-hexanone 8.01
    octyl acetate 4.36
    limonene 0.44
    1,2-dimethoxyethane 41.79
    ethyl orthosilicate 2.36
    tributyl phosphate 3.23
    diacetone alcohol 19.26
    N,N-dimethylaniline 2.02
    acrylonitrile 8.58
    aniline 1.62
    1,3-propanediol 21.99
    bromobenzene 0.15
    dibromomethane 0.16
    1,1,2,2-tetrachloroethane 1.4
    2-methyl-cyclohexyl acetate 3.54
    tetrabutyl urea 7.44
    diisobutyl methanol 1.06
    2-phenylethanol 5.76
    styrene 0.27
    dioctyl adipate 5.61
    dimethyl sulfate 8.05
    ethyl butyrate 4.48
    methyl lactate 19.4
    butyl lactate 11.92
    diethyl carbonate 2.97
    propanediol butyl ether 22.78
    triethyl orthoformate 4.21
    p-tert-butyltoluene 0.33
    methyl 4-tert-butylbenzoate 8.14
    morpholine 20.73
    tert-butylamine 0.65
    n-dodecanol 1.74
    dimethoxymethane 42.85
    ethylene carbonate 4.47
    cyrene 15.2
    2-ethoxyethyl acetate 16.41
    2-ethylhexyl acetate 2.92
    1,2,4-trichlorobenzene 0.72
    4-methylpyridine 4.35
    dibutyl ether 2.32
    2,6-dimethyl-4-heptanol 1.06
    DEF 19.67
    dimethyl isosorbide 22.88
    tetrachloroethylene 0.63
    eugenol 14.66
    triacetin 10.11
    span 80 14.2
    1,4-butanediol 6.81
    1,1-dichloroethane 0.27
    2-methyl-1-pentanol 3.61
    methyl formate 18.43
    2-methyl-1-butanol 4.87
    n-decane 0.06
    butyronitrile 3.9
    3,7-dimethyl-1-octanol 2.32
    1-chlorooctane 0.33
    1-chlorotetradecane 0.23
    n-nonane 0.04
    undecane 0.05
    tert-butylcyclohexane 0.01
    cyclooctane 0.0
    cyclopentanol 3.78
    tetrahydropyran 4.43
    tert-amyl methyl ether 2.53
    2,5,8-trioxanonane 36.9
    1-hexene 0.07
    2-isopropoxyethanol 15.9
    2,2,2-trifluoroethanol 3.47
    methyl butyrate 7.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction