Enokipodin A

Overview IFRA Request a quote

  • Identifiers

    CAS number
    306951-07-5

    Molecular formula
    C15H20O3

    SMILES
    CC1=CC2=C(C=C1O)[C@]3(CC[C@](C3(C)C)(O2)O)C

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 51.09%
    Sweet 40.37%
    Woody 39.36%
    Spicy 39.03%
    Musk 28.94%
    Dry 28.82%
    Powdery 28.06%
    Smoky 28.05%
    Balsamic 27.67%
    Leathery 27.62%

     

    Flavor
    Bitter 69.54%
    Camphor 39.74%
    Woody 36.53%
    Phenolic 29.43%
    Medicinal 26.2%
    Musty 24.13%
    Eugenol 23.65%
    Earth 23.12%
    Ripe apricot 22.37%
    Cedarleaf 22.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    7.88 (neutral)

    Molecular weight
    248.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    461°C

    Flash point

    • 218.85 ˚C est.

  • Synonyms

    • enokipodin A
    • DTXSID001317949
    • 306951-07-5
    • RefChem:81255
    • 1,5,12,12-tetramethyl-8-oxatricyclo(7.2.1.0^(2,7))dodeca-2,4,6-triene-4,9-diol
    • DTXCID801747742
    • 1,5,12,12-tetramethyl-8-oxatricyclo(7.2.1.02,7)dodeca-2(7),3,5-triene-4,9-diol
    • (1R,9R)-1,5,12,12-Tetramethyl-8-oxatricyclo[7.2.1.02,7]dodeca-2(7),3,5-triene-4,9-diol
    • 2,3,4,5-tetrahydro-2,7-dihydroxy-5,8,10,10-tetramethyl-2,5-methano-1-benzoxepin
    • CHEMBL509199
    • CHEBI:199698
    • (2R,5R)-5,8,10,10-Tetramethyl-4,5-dihydro-2,5-methano-1-benzoxepine-2,7(3H)-diol
    • 306951-07-5

  • Applications

    Enokipodin A (CAS 306951-07-5) is primarily used as an intermediate in organic synthesis and as a research reagent in medicinal chemistry, with potential as a precursor for derivatives in natural product-inspired synthesis. It may be employed as a reference analytical standard for characterizing related compounds, and as a specialty starting material for process development in fine chemical production. In addition, it could be explored as a building block in polymer and materials science research. All applications are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 182.71
    methanol 376.63
    isopropanol 146.44
    water 7.17
    ethyl acetate 181.53
    n-propanol 136.36
    acetone 393.25
    n-butanol 120.69
    acetonitrile 150.72
    DMF 855.68
    toluene 78.66
    isobutanol 88.19
    1,4-dioxane 530.83
    methyl acetate 212.45
    THF 651.08
    2-butanone 226.72
    n-pentanol 69.77
    sec-butanol 78.79
    n-hexane 2.64
    ethylene glycol 73.05
    NMP 230.62
    cyclohexane 7.72
    DMSO 418.37
    n-butyl acetate 108.43
    n-octanol 45.04
    chloroform 314.13
    n-propyl acetate 109.14
    acetic acid 148.43
    dichloromethane 249.26
    cyclohexanone 237.51
    propylene glycol 52.49
    isopropyl acetate 134.67
    DMAc 419.31
    2-ethoxyethanol 207.94
    isopentanol 99.96
    n-heptane 3.99
    ethyl formate 156.84
    1,2-dichloroethane 156.37
    n-hexanol 86.61
    2-methoxyethanol 421.07
    isobutyl acetate 86.38
    tetrachloromethane 54.61
    n-pentyl acetate 86.5
    transcutol 260.92
    n-heptanol 61.89
    ethylbenzene 51.77
    MIBK 121.79
    2-propoxyethanol 264.53
    tert-butanol 162.83
    MTBE 107.49
    2-butoxyethanol 144.53
    propionic acid 95.35
    o-xylene 56.08
    formic acid 141.33
    diethyl ether 116.85
    m-xylene 64.94
    p-xylene 96.64
    chlorobenzene 92.91
    dimethyl carbonate 170.51
    n-octane 2.92
    formamide 362.43
    cyclopentanone 355.24
    2-pentanone 176.49
    anisole 139.25
    cyclopentyl methyl ether 131.15
    gamma-butyrolactone 342.07
    1-methoxy-2-propanol 293.25
    pyridine 246.94
    3-pentanone 123.82
    furfural 292.63
    n-dodecane 3.05
    diethylene glycol 247.91
    diisopropyl ether 36.71
    tert-amyl alcohol 86.94
    acetylacetone 288.25
    n-hexadecane 3.64
    acetophenone 134.72
    methyl propionate 161.23
    isopentyl acetate 108.33
    trichloroethylene 307.89
    n-nonanol 49.21
    cyclohexanol 81.29
    benzyl alcohol 119.94
    2-ethylhexanol 46.34
    isooctanol 52.66
    dipropyl ether 53.3
    1,2-dichlorobenzene 94.83
    ethyl lactate 63.94
    propylene carbonate 162.23
    n-methylformamide 364.13
    2-pentanol 62.12
    n-pentane 3.64
    1-propoxy-2-propanol 134.69
    1-methoxy-2-propyl acetate 154.79
    2-(2-methoxypropoxy) propanol 108.39
    mesitylene 42.52
    ε-caprolactone 176.14
    p-cymene 33.45
    epichlorohydrin 361.34
    1,1,1-trichloroethane 160.49
    2-aminoethanol 110.59
    morpholine-4-carbaldehyde 446.76
    sulfolane 284.0
    2,2,4-trimethylpentane 3.37
    2-methyltetrahydrofuran 185.71
    n-hexyl acetate 94.34
    isooctane 3.75
    2-(2-butoxyethoxy)ethanol 149.35
    sec-butyl acetate 77.21
    tert-butyl acetate 134.33
    decalin 6.35
    glycerin 108.51
    diglyme 303.42
    acrylic acid 95.9
    isopropyl myristate 45.17
    n-butyric acid 136.69
    acetyl acetate 163.53
    di(2-ethylhexyl) phthalate 52.92
    ethyl propionate 97.22
    nitromethane 454.55
    1,2-diethoxyethane 120.95
    benzonitrile 125.66
    trioctyl phosphate 40.51
    1-bromopropane 56.15
    gamma-valerolactone 503.68
    n-decanol 37.18
    triethyl phosphate 52.35
    4-methyl-2-pentanol 52.22
    propionitrile 116.25
    vinylene carbonate 202.39
    1,1,2-trichlorotrifluoroethane 212.44
    DMS 127.83
    cumene 38.33
    2-octanol 40.41
    2-hexanone 112.73
    octyl acetate 56.3
    limonene 35.27
    1,2-dimethoxyethane 454.97
    ethyl orthosilicate 51.96
    tributyl phosphate 43.03
    diacetone alcohol 146.2
    N,N-dimethylaniline 95.97
    acrylonitrile 176.73
    aniline 108.99
    1,3-propanediol 181.23
    bromobenzene 85.34
    dibromomethane 125.91
    1,1,2,2-tetrachloroethane 233.54
    2-methyl-cyclohexyl acetate 78.92
    tetrabutyl urea 65.52
    diisobutyl methanol 36.67
    2-phenylethanol 127.64
    styrene 56.75
    dioctyl adipate 61.79
    dimethyl sulfate 213.59
    ethyl butyrate 79.79
    methyl lactate 104.71
    butyl lactate 67.54
    diethyl carbonate 67.73
    propanediol butyl ether 91.01
    triethyl orthoformate 65.11
    p-tert-butyltoluene 33.65
    methyl 4-tert-butylbenzoate 108.4
    morpholine 446.54
    tert-butylamine 73.98
    n-dodecanol 27.94
    dimethoxymethane 537.4
    ethylene carbonate 169.03
    cyrene 134.19
    2-ethoxyethyl acetate 138.82
    2-ethylhexyl acetate 79.77
    1,2,4-trichlorobenzene 101.79
    4-methylpyridine 206.8
    dibutyl ether 43.49
    2,6-dimethyl-4-heptanol 36.67
    DEF 177.1
    dimethyl isosorbide 188.86
    tetrachloroethylene 164.1
    eugenol 123.97
    triacetin 111.89
    span 80 81.79
    1,4-butanediol 67.45
    1,1-dichloroethane 151.92
    2-methyl-1-pentanol 61.79
    methyl formate 298.82
    2-methyl-1-butanol 73.34
    n-decane 5.11
    butyronitrile 115.65
    3,7-dimethyl-1-octanol 44.0
    1-chlorooctane 21.32
    1-chlorotetradecane 10.38
    n-nonane 3.77
    undecane 3.8
    tert-butylcyclohexane 5.85
    cyclooctane 3.24
    cyclopentanol 100.85
    tetrahydropyran 235.68
    tert-amyl methyl ether 64.27
    2,5,8-trioxanonane 198.52
    1-hexene 14.34
    2-isopropoxyethanol 132.41
    2,2,2-trifluoroethanol 113.12
    methyl butyrate 127.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction