Edetol

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  • Identifiers

    CAS number
    102-60-3

    Molecular formula
    C14H32N2O4

    SMILES
    CC(CN(CCN(CC(C)O)CC(C)O)CC(C)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 49.36%
    Odorless 43.76%
    Sweet 34.62%
    Alcoholic 22.97%
    Savory 20.81%
    Oily 19.77%
    Cooling 17.58%
    Ripe 16.83%
    Animal 16.44%
    Cheesy 16.18%

     

    Flavor
    Odorless 44.52%
    Mild 31.3%
    Sulfurous 25.87%
    Bland 23.59%
    Sweet-like 23.1%
    Bitter 22.29%
    Yeasty 20.68%
    Bouillon 19.75%
    Very slight 19.68%
    Rose acetate 19.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    7.4 (neutral)

    Molecular weight
    292.41 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 190 °C @ 1.0 MM HG

    Flash point

    • 203.43 ˚C est.

    Solubility expt.

    • MISCIBLE WITH WATER; SOL IN METHANOL, ETHANOL, TOLUENE, ETHYLENE GLYCOL, PERCHLOROETHYLENE

  • Synonyms

    • 102-60-3
    • Edetol
    • N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
    • Neutrol TE
    • Adeka Quadrol
    • Quadrol L
    • 1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol
    • Edetolum [Latin]
    • Edetolum
    • 2-Propanol, 1,1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
    • Edetol [USAN:INN]
    • NSC 369219
    • TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE
    • HSDB 5349
    • EINECS 203-041-4
    • UNII-Q4R969U9FR
    • NSC-369219
    • Edetol (USAN)
    • BRN 1781143
    • Neutrol TE (TN)
    • CCRIS 8275
    • Ethylenediamine-N,N,N',N'-tetra-2-propanol
    • EDETOL [HSDB]
    • EDETOL [USAN]
    • EDETOL [INN]
    • 2-Propanol, 1',1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
    • EC 203-041-4
    • Edetolum (Latin)
    • 4-04-00-01685 (Beilstein Handbook Reference)
    • Tetra (2-hydroxypropyl) ethylenediamine
    • n,n,n',n'-tetrakis (2-hydroxypropyl) ethylenediamine
    • 1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL)
    • RefChem:136287
    • Tetrakis(2hydroxypropyl)ethylenediamine
    • N,N,N',N'Tetra(2hydroxypropyl)ethylenediamine
    • 1,1',1',1'''(Ethylenedinitrilo)tetra2propanol
    • 1,1',1'',1'''(Ethylenedinitrilo)tetra2propanol
    • N,N,N',N'Tetrakis(2hydroxypropyl)ethylenediamine
    • 2Propanol, 1,1',1'',1'''(ethylenedinitrilo)tetra
    • 1,1',1'',1'''(Ethylenedinitrilo)tetrakis(2propanol)
    • 2Propanol, 1,1',1',1'''(1,2ethanediyldinitrilo)tetrakis
    • 203-041-4
    • NSOXQYCFHDMMGV-UHFFFAOYSA-N
    • Quadrol
    • Entprol
    • 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol)
    • Tetrahydroxypropyl ethylenediamine
    • MFCD00004534
    • 1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol
    • N,N,N',N'-Tetra(2-hydroxypropyl)ethylenediamine
    • 1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol
    • 2-Propanol, 1,1',1'',1'''-(ethylenedinitrilo)tetra-
    • 1,1',1'',1'''-(Ethylenedinitrilo)tetrakis(2-propanol)
    • Q4R969U9FR
    • DTXSID9026689
    • NNN'N'-Tetrakis(2-Hydroxypropyl)ethylenediamine
    • N,N,N,N-Tetrakis(2-Hydroxypropyl)- Ethylenediamine
    • 1,1',1'',1'''-(Ethanediylnitrilo)tetrakis(2-propanol)
    • NCGC00164339-02
    • DTXCID806689
    • N,N,N',N'-Tetrakis(2-Hydroxypropyl)ethylenediamine, 98%
    • CAS-102-60-3
    • n,n,n,n-tetrakis(2-hydroxypropyl)ethylenediamine
    • (Ethylenedinitrilo)tetra-2-propanol
    • N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine;EDTP
    • Quadrol(R)
    • ENTPROL [MI]
    • SCHEMBL48412
    • MLS004773924
    • 1,1',1',1'''-(Ethylenedinitrilo)tetra-2-propanol
    • orb1306107
    • CHEMBL1573178
    • CHEBI:193592
    • HMS3264C08
    • Pharmakon1600-01301023
    • 2-Propanol, 1,1',1',1'''-(1,2-ethanediyldinitrilo)tetrakis-
    • HY-B2149
    • Tox21_112102
    • Tox21_201973
    • Tox21_300552
    • NSC369219
    • NSC760394
    • tetra(2-hydroxypropyl)ethylenediamine
    • 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))-tetrakis(propan-2-ol)
    • 1-({2-[bis(2-hydroxypropyl)amino]ethyl}(2-hydroxypropyl)amino)propan-2-ol
    • AKOS015892820
    • Tox21_112102_1
    • CCG-230630
    • NSC-760394
    • SB82446
    • NCGC00164339-01
    • NCGC00164339-03
    • NCGC00164339-04
    • NCGC00164339-05
    • NCGC00254289-01
    • NCGC00259522-01
    • BS-23689
    • DA-52809
    • SMR001600027
    • SY011184
    • CS-0020301
    • ethane, 1,2-bis(di-2-hydroxypropylamino)-
    • NS00009765
    • ST50308044
    • T0781
    • D03948
    • F71260
    • Tetrakis-[N-(2-hydroxy-propyl)]-ethylenediamine
    • A800588
    • BRD-A78588743-001-03-4
    • N,N,N',N'-tetrakis-(2-hydroxypropyl)ethylenediamine
    • N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine;EDTP
    • Q26841009
    • 4,7-Diazadecane-2,9-diol, 4,7-bis(2-hydroxypropyl)-
    • N,N,N',N'-Tetrakis(2-hydroxyprop-1-yl)ethane-1,2-diamine
    • 1,1',1'',1'''-(Ethane-1,2-diyldinitrilo)tetra(propan-2-ol)
    • 1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]-2-propanol
    • 1-[2-[bis(2-oxidanylpropyl)amino]ethyl-(2-oxidanylpropyl)amino]propan-2-ol
    • 1,1a(2),1a(2)a(2),1a(2)a(2)a(2)-(Ethylenedinitrilo)tetrakis(2-propanol)
    • N,N,N inverted exclamation mark ,N inverted exclamation mark -Tetrakis(2-Hydroxypropyl)ethylenediamine
    • N,N,N inverted exclamation marka,N inverted exclamation marka-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP
    • 102-60-3

  • Applications

    Edetol is commonly used as a solvent and processing aid in industrial coatings, inks, and adhesives, helping dissolve resins and improve formulation compatibility. It may serve as an organic synthesis intermediate and as a co-solvent or processing aid in certain polymer and plastics formulations. In fragrance and cosmetics, it can act as a solvent or a fixative component, while in cleaning products it functions as a solvent to dissolve formulation ingredients. It is encountered in industrial manufacturing as a specialty solvent and may be evaluated for use in electronics-related coatings or other coating/formulation applications, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 43.77
    methanol 231.42
    isopropanol 8.05
    water 740.4
    ethyl acetate 5.35
    n-propanol 31.78
    acetone 2.7
    n-butanol 12.74
    acetonitrile 3.14
    DMF 75.93
    toluene 1.27
    isobutanol 14.22
    1,4-dioxane 4.93
    methyl acetate 6.48
    THF 12.68
    2-butanone 5.14
    n-pentanol 6.98
    sec-butanol 10.58
    n-hexane 0.75
    ethylene glycol 151.22
    NMP 304.25
    cyclohexane 1.08
    DMSO 112.3
    n-butyl acetate 6.74
    n-octanol 4.78
    chloroform 12.31
    n-propyl acetate 5.24
    acetic acid 313.23
    dichloromethane 12.11
    cyclohexanone 20.52
    propylene glycol 120.18
    isopropyl acetate 3.36
    DMAc 113.31
    2-ethoxyethanol 41.42
    isopentanol 5.74
    n-heptane 0.99
    ethyl formate 12.72
    1,2-dichloroethane 7.11
    n-hexanol 8.56
    2-methoxyethanol 97.51
    isobutyl acetate 3.81
    tetrachloromethane 3.67
    n-pentyl acetate 5.03
    transcutol 53.98
    n-heptanol 6.61
    ethylbenzene 1.1
    MIBK 2.29
    2-propoxyethanol 41.4
    tert-butanol 5.77
    MTBE 1.73
    2-butoxyethanol 25.2
    propionic acid 114.46
    o-xylene 2.76
    formic acid 849.86
    diethyl ether 1.74
    m-xylene 1.92
    p-xylene 1.47
    chlorobenzene 1.9
    dimethyl carbonate 8.17
    n-octane 0.41
    formamide 405.02
    cyclopentanone 28.93
    2-pentanone 3.28
    anisole 1.83
    cyclopentyl methyl ether 10.79
    gamma-butyrolactone 74.0
    1-methoxy-2-propanol 39.11
    pyridine 8.38
    3-pentanone 5.06
    furfural 66.3
    n-dodecane 0.18
    diethylene glycol 67.97
    diisopropyl ether 0.74
    tert-amyl alcohol 10.17
    acetylacetone 5.6
    n-hexadecane 0.19
    acetophenone 6.15
    methyl propionate 13.02
    isopentyl acetate 5.72
    trichloroethylene 15.58
    n-nonanol 4.37
    cyclohexanol 16.12
    benzyl alcohol 7.72
    2-ethylhexanol 4.72
    isooctanol 4.76
    dipropyl ether 3.6
    1,2-dichlorobenzene 3.52
    ethyl lactate 18.29
    propylene carbonate 36.25
    n-methylformamide 108.32
    2-pentanol 4.96
    n-pentane 0.74
    1-propoxy-2-propanol 23.63
    1-methoxy-2-propyl acetate 13.9
    2-(2-methoxypropoxy) propanol 19.86
    mesitylene 1.45
    ε-caprolactone 38.77
    p-cymene 2.23
    epichlorohydrin 24.73
    1,1,1-trichloroethane 3.6
    2-aminoethanol 194.24
    morpholine-4-carbaldehyde 103.56
    sulfolane 206.14
    2,2,4-trimethylpentane 0.67
    2-methyltetrahydrofuran 9.47
    n-hexyl acetate 6.4
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 23.94
    sec-butyl acetate 3.12
    tert-butyl acetate 3.75
    decalin 0.7
    glycerin 267.24
    diglyme 32.78
    acrylic acid 165.54
    isopropyl myristate 1.63
    n-butyric acid 53.41
    acetyl acetate 5.34
    di(2-ethylhexyl) phthalate 6.31
    ethyl propionate 6.19
    nitromethane 101.14
    1,2-diethoxyethane 3.53
    benzonitrile 3.93
    trioctyl phosphate 4.7
    1-bromopropane 2.65
    gamma-valerolactone 72.82
    n-decanol 2.63
    triethyl phosphate 7.97
    4-methyl-2-pentanol 2.54
    propionitrile 4.22
    vinylene carbonate 38.14
    1,1,2-trichlorotrifluoroethane 149.76
    DMS 10.14
    cumene 1.4
    2-octanol 3.06
    2-hexanone 2.82
    octyl acetate 3.06
    limonene 3.25
    1,2-dimethoxyethane 12.61
    ethyl orthosilicate 6.88
    tributyl phosphate 5.94
    diacetone alcohol 12.84
    N,N-dimethylaniline 3.62
    acrylonitrile 8.9
    aniline 6.07
    1,3-propanediol 86.64
    bromobenzene 1.36
    dibromomethane 7.01
    1,1,2,2-tetrachloroethane 14.79
    2-methyl-cyclohexyl acetate 7.91
    tetrabutyl urea 8.04
    diisobutyl methanol 2.25
    2-phenylethanol 7.49
    styrene 0.85
    dioctyl adipate 4.22
    dimethyl sulfate 34.3
    ethyl butyrate 6.34
    methyl lactate 35.89
    butyl lactate 17.15
    diethyl carbonate 4.88
    propanediol butyl ether 32.84
    triethyl orthoformate 7.16
    p-tert-butyltoluene 2.25
    methyl 4-tert-butylbenzoate 13.68
    morpholine 16.91
    tert-butylamine 3.06
    n-dodecanol 1.65
    dimethoxymethane 12.9
    ethylene carbonate 24.5
    cyrene 51.44
    2-ethoxyethyl acetate 8.68
    2-ethylhexyl acetate 5.08
    1,2,4-trichlorobenzene 5.74
    4-methylpyridine 5.33
    dibutyl ether 1.65
    2,6-dimethyl-4-heptanol 2.25
    DEF 18.58
    dimethyl isosorbide 35.49
    tetrachloroethylene 17.02
    eugenol 15.9
    triacetin 17.15
    span 80 23.55
    1,4-butanediol 34.05
    1,1-dichloroethane 2.71
    2-methyl-1-pentanol 4.66
    methyl formate 50.41
    2-methyl-1-butanol 10.98
    n-decane 0.4
    butyronitrile 2.56
    3,7-dimethyl-1-octanol 3.4
    1-chlorooctane 1.35
    1-chlorotetradecane 0.4
    n-nonane 0.4
    undecane 0.26
    tert-butylcyclohexane 0.62
    cyclooctane 0.65
    cyclopentanol 24.11
    tetrahydropyran 4.93
    tert-amyl methyl ether 3.66
    2,5,8-trioxanonane 24.08
    1-hexene 1.22
    2-isopropoxyethanol 15.38
    2,2,2-trifluoroethanol 199.4
    methyl butyrate 8.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction