Edetate Trisodium

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  • Identifiers

    CAS number
    150-38-9

    Molecular formula
    C10H13N2Na3O8

    SMILES
    C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].[Na+].[Na+].[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 66.34%
    Sweet 37.98%
    Savory 25.82%
    Fishy 19.6%
    Alcoholic 18.05%
    Meaty 14.83%
    Clean 14.8%
    Oily 14.7%
    Cooked 14.05%
    Milky 14.03%

     

    Flavor
    Odorless 62.34%
    Bitter 37.58%
    Bland 32.08%
    Mild 31.59%
    Very mild 24.98%
    Sweet-like 21.77%
    Yeast 21.44%
    Faint 19.56%
    Bread crust 19.18%
    Nitrile 19.12%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    -0.3 (strong acid)

    Molecular weight
    358.19 g/mol

    Melting point expt.

    • greater than 572 °F (NTP, 1992)

    Flash point

    • 272.13 ˚C est.

    Solubility expt.

    • 5 to 10 mg/mL at 70.7 °F (NTP, 1992)

  • Synonyms

    • Edetate trisodium
    • 150-38-9
    • Trisodium EDTA
    • EDTA trisodium salt
    • Trisodium ethylenediaminetetraacetate
    • Versene-9
    • Edetate Trisodium [USAN]
    • CCRIS 294
    • UNII-420IP921MB
    • EDTA trisodium salt (trihydrate)
    • 420IP921MB
    • Trisodium hydrogen ethylenediaminetetraacetate
    • EINECS 205-758-8
    • Edetate trisodium (USAN)
    • NSC-756746
    • AI3-18050
    • DTXSID7020556
    • EDETATE TRISODIUM [VANDF]
    • EDTA TRISODIUM SALT [MI]
    • TRISODIUM EDETATE [MART.]
    • Trisodium hydrogen(ethylenedinitrilo)tetraacetate
    • NSC 756746
    • Ethylenediaminetetraacetic acid, trisodium salt, trihydrate
    • trisodium salt of ethylenediaminetetraacetic acid
    • (Ethylenedinitrilo)tetraacetic acid trisodium salt
    • TRISODIUM EDETATE (MART.)
    • N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), trisodium salt
    • trisodium 2,2'-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}imino)diacetate
    • NevanaidB powder
    • Hampene Na3T
    • trisodium 2,2'-((2-((carboxylatomethyl)(carboxymethyl)amino)ethyl)imino)diacetate
    • hamp-ene na3 t
    • TRISODIUM ETDA
    • RefChem:136285
    • DTXCID30556
    • TRISODIUM EDTA [INCI]
    • Acetic acid, (ethylenedinitrilo)tetra, trisodium salt
    • ETHYLENEDIAMINE TETRAACETIC ACID, TRISODIUM SALT
    • Glycine, N,N'1,2ethanediylbis(N(carboxymethyl), trisodium salt
    • Glycine, N,N'1,2ethanediylbis(Ncarboxymethyl, trisodium salt
    • N,N'1,2Ethanediylbis(N(carboxymethyl)glycine), trisodium salt
    • Glycine, N,N'1,2ethanediylbis(N(carboxymethyl), sodium salt (1:3)
    • Ethylenediaminetetraacetic acid trisodium salt
    • edta trisodium
    • Trisodium edetate
    • Limclair
    • EDTA, 0.5 M, pH 8.0
    • Trisodium ethylenediamine tetraacetate
    • ethylenediaminetetraacetic acid trisodium
    • EDTA, trisodium salt trihydrate
    • EDTA 3Na
    • EDTA trisodium salt hydrate
    • Sequestrene Na3
    • Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, trisodium salt, hydrate
    • Trilon AO
    • Nevanaid-B powder
    • Versene 9
    • Trisodium versenate
    • Sequestrene trisodium
    • Sequestrene trisodium salt
    • Perma kleer 50, trisodium salt
    • tri-sodium edetate
    • Trinatrium ethylendiamintetraacetat
    • NCI-C03974
    • (Ethylenedinitrilo)tetraacetic acid trisodium salt hydrate
    • EDTA pound not3Na
    • Ethylenediamineacetic acid trisodium salt
    • Trinatrium ethylendiamintetraacetat [Czech]
    • Ethylenediaminetetraacetic acid, trisodium salt
    • trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate
    • SCHEMBL59899
    • Trisodium hydrogen (ethylenedinitrilo)tetraacetate
    • C10H13N2Na3O8
    • orb1310632
    • CHEMBL2028177
    • CHEBI:63125
    • TRISODIUM EDETATE [WHO-DD]
    • EDTA trisodium salt;Trisodium EDTA
    • MFCD00013305
    • AKOS015902870
    • AKOS030526100
    • CCG-268131
    • FT126354
    • KITELOCK COMPONENT EDETATE TRISODIUM
    • DB-043053
    • E0430
    • T2599
    • Trisodium hydrogen ethylene diaminetetraacetate
    • D03947
    • F85209
    • Acetic acid, (ethylenedinitrilo)tetra-, trisodium salt
    • Q27132403
    • Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, trisodium salt
    • Glycine, N,N'-1,2-ethanediylbis(N-carboxymethyl-, trisodium salt
    • N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine] trisodium salt
    • Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:3)
    • Tetrasodium 2-[2-(bis(carboxylatomethyl)amino)Ethyl-(carboxylatomethyl) amino] acetate
    • Trisodium 2,2'-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}azanediyl)diacetate
    • 150-38-9

  • Applications

    Edetate Trisodium (tri-sodium EDTA) acts as a chelating and sequestering agent to bind trace metal ions, improving the stability and performance of formulations and processes. Common applications include use in household and industrial cleaners to soften water and prevent metal-catalyzed degradation; in cosmetics and personal care products to improve stability and color retention; in food processing as a sequestrant to help preserve texture and appearance; in pharmaceutical and medical formulations as a chelating/stabilizing agent; in coatings, inks, and polymer formulations to prevent metal-induced defects; and in various industrial manufacturing and water-treatment operations such as metal finishing, papermaking, and dyeing to control scale and fouling.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.63
    methanol 4.68
    isopropanol 0.1
    water 3.21
    ethyl acetate 0.07
    n-propanol 0.29
    acetone 0.27
    n-butanol 0.12
    acetonitrile 0.09
    DMF 33.92
    toluene 0.05
    isobutanol 0.11
    1,4-dioxane 0.04
    methyl acetate 0.15
    THF 0.33
    2-butanone 0.27
    n-pentanol 0.04
    sec-butanol 0.11
    n-hexane 0.01
    ethylene glycol 2.26
    NMP 58.73
    cyclohexane 0.0
    DMSO 50.62
    n-butyl acetate 0.09
    n-octanol 0.03
    chloroform 0.09
    n-propyl acetate 0.05
    acetic acid 2.29
    dichloromethane 0.18
    cyclohexanone 0.43
    propylene glycol 1.99
    isopropyl acetate 0.04
    DMAc 23.0
    2-ethoxyethanol 0.56
    isopentanol 0.05
    n-heptane 0.01
    ethyl formate 0.3
    1,2-dichloroethane 0.13
    n-hexanol 0.05
    2-methoxyethanol 3.94
    isobutyl acetate 0.02
    tetrachloromethane 0.02
    n-pentyl acetate 0.04
    transcutol 1.14
    n-heptanol 0.04
    ethylbenzene 0.03
    MIBK 0.07
    2-propoxyethanol 0.76
    tert-butanol 0.08
    MTBE 0.02
    2-butoxyethanol 0.29
    propionic acid 0.98
    o-xylene 0.1
    formic acid 21.25
    diethyl ether 0.03
    m-xylene 0.05
    p-xylene 0.03
    chlorobenzene 0.03
    dimethyl carbonate 0.53
    n-octane 0.0
    formamide 24.31
    cyclopentanone 1.05
    2-pentanone 0.16
    anisole 0.07
    cyclopentyl methyl ether 0.15
    gamma-butyrolactone 2.01
    1-methoxy-2-propanol 1.67
    pyridine 0.35
    3-pentanone 0.22
    furfural 4.0
    n-dodecane 0.0
    diethylene glycol 1.55
    diisopropyl ether 0.01
    tert-amyl alcohol 0.12
    acetylacetone 0.26
    n-hexadecane 0.0
    acetophenone 0.28
    methyl propionate 0.42
    isopentyl acetate 0.07
    trichloroethylene 0.33
    n-nonanol 0.03
    cyclohexanol 0.07
    benzyl alcohol 0.17
    2-ethylhexanol 0.04
    isooctanol 0.03
    dipropyl ether 0.07
    1,2-dichlorobenzene 0.06
    ethyl lactate 0.4
    propylene carbonate 0.55
    n-methylformamide 11.81
    2-pentanol 0.04
    n-pentane 0.01
    1-propoxy-2-propanol 0.53
    1-methoxy-2-propyl acetate 0.35
    2-(2-methoxypropoxy) propanol 0.68
    mesitylene 0.03
    ε-caprolactone 0.46
    p-cymene 0.05
    epichlorohydrin 0.59
    1,1,1-trichloroethane 0.04
    2-aminoethanol 3.14
    morpholine-4-carbaldehyde 7.52
    sulfolane 19.39
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.09
    n-hexyl acetate 0.05
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 0.43
    sec-butyl acetate 0.03
    tert-butyl acetate 0.06
    decalin 0.0
    glycerin 8.44
    diglyme 0.93
    acrylic acid 2.42
    isopropyl myristate 0.02
    n-butyric acid 0.45
    acetyl acetate 0.05
    di(2-ethylhexyl) phthalate 0.08
    ethyl propionate 0.1
    nitromethane 3.14
    1,2-diethoxyethane 0.04
    benzonitrile 0.08
    trioctyl phosphate 0.05
    1-bromopropane 0.04
    gamma-valerolactone 3.03
    n-decanol 0.02
    triethyl phosphate 0.2
    4-methyl-2-pentanol 0.02
    propionitrile 0.11
    vinylene carbonate 0.79
    1,1,2-trichlorotrifluoroethane 4.26
    DMS 0.16
    cumene 0.03
    2-octanol 0.02
    2-hexanone 0.06
    octyl acetate 0.03
    limonene 0.06
    1,2-dimethoxyethane 0.48
    ethyl orthosilicate 0.13
    tributyl phosphate 0.07
    diacetone alcohol 0.42
    N,N-dimethylaniline 0.22
    acrylonitrile 0.42
    aniline 0.18
    1,3-propanediol 1.07
    bromobenzene 0.02
    dibromomethane 0.09
    1,1,2,2-tetrachloroethane 0.25
    2-methyl-cyclohexyl acetate 0.1
    tetrabutyl urea 0.22
    diisobutyl methanol 0.03
    2-phenylethanol 0.12
    styrene 0.03
    dioctyl adipate 0.05
    dimethyl sulfate 4.39
    ethyl butyrate 0.13
    methyl lactate 2.26
    butyl lactate 0.26
    diethyl carbonate 0.09
    propanediol butyl ether 0.45
    triethyl orthoformate 0.12
    p-tert-butyltoluene 0.04
    methyl 4-tert-butylbenzoate 0.38
    morpholine 0.2
    tert-butylamine 0.03
    n-dodecanol 0.01
    dimethoxymethane 1.51
    ethylene carbonate 0.27
    cyrene 1.85
    2-ethoxyethyl acetate 0.08
    2-ethylhexyl acetate 0.05
    1,2,4-trichlorobenzene 0.09
    4-methylpyridine 0.31
    dibutyl ether 0.02
    2,6-dimethyl-4-heptanol 0.03
    DEF 1.21
    dimethyl isosorbide 1.35
    tetrachloroethylene 0.25
    eugenol 0.42
    triacetin 0.18
    span 80 0.34
    1,4-butanediol 0.21
    1,1-dichloroethane 0.04
    2-methyl-1-pentanol 0.03
    methyl formate 4.27
    2-methyl-1-butanol 0.1
    n-decane 0.0
    butyronitrile 0.05
    3,7-dimethyl-1-octanol 0.03
    1-chlorooctane 0.01
    1-chlorotetradecane 0.0
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.12
    tetrahydropyran 0.03
    tert-amyl methyl ether 0.06
    2,5,8-trioxanonane 0.79
    1-hexene 0.02
    2-isopropoxyethanol 0.12
    2,2,2-trifluoroethanol 1.71
    methyl butyrate 0.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction