Ecamsule

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  • Identifiers

    CAS number
    92761-26-7

    Molecular formula
    C28H34O8S2

    SMILES
    CC1(C2CCC1(C(=O)C2=CC3=CC=C(C=C3)C=C4C5CCC(C4=O)(C5(C)C)CS(=O)(=O)O)CS(=O)(=O)O)C

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Odorless 59.26%
    Cooling 23.62%
    Woody 23.36%
    Mint 20.38%
    Green 19.87%
    Fresh 18.91%
    Spicy 17.9%
    Herbal 17.74%
    Balsamic 17.18%
    Dry 15.88%

     

    Flavor
    Bitter 91.38%
    Odorless 21.27%
    Bland 19.61%
    Cedarleaf 19.33%
    Nitrile 18.85%
    Heather 17.95%
    Lovage 17.93%
    Broom 17.81%
    Ripe apricot 17.78%
    Genet 17.47%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.1

    pKa est.
    2.37 (strong acid)

    Molecular weight
    562.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    592°C

    Melting point expt.

    • 255 °C (decomposes)

    Flash point

    • 301.9 ˚C est.

  • Synonyms

    • Ecamsule
    • 92761-26-7
    • Terephthalylidene dicamphor sulfonic acid
    • Ecamsul
    • Mexoryl
    • Mexoryl SX
    • DTXSID80869056
    • M94R1PM439
    • Ecamsulum
    • NSC-760054
    • RefChem:590537
    • DTXCID50817089
    • (3-((4-((7,7-dimethyl-3-oxo-4-(sulfomethyl)bicyclo(2.2.1)heptan-2-ylidene)methyl)phenyl)methylidene)-7,7-dimethyl-2-oxobicyclo(2.2.1)heptan-1-yl)methanesulfonic acid
    • (E-E)-3,3'-(1,4-Phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid)
    • 410-960-6
    • 922-216-2
    • 90457-82-2
    • [3-[[4-[[7,7-dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid
    • C28H34O8S2
    • 3,3'-(1,4-Phenylenedimethylidyne)bis(7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfonic acid)
    • [(3E)-3-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid
    • Ecamsule [USAN:USP:INN]
    • UNII-M94R1PM439
    • orb1298413
    • CHEMBL3989850
    • SCHEMBL29355054
    • HSDB 8476
    • CHEBI:135830
    • Bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-
    • MSK40353
    • terephthalylidenedicamphorsulfonic acid
    • terephthalylidenedicamphorsulphonic acid
    • NSC 760054
    • Terephthalylidenedicamphor sulphonic acid
    • [(3E)-3-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-yliden e]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methane sulfonic acid
    • DB-091412
    • DB-256161
    • EC 410-960-6
    • (+-)-(3E,3'E)-(p-Phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid)
    • (+-)-(3E,3'E)-3,3'-(p-Phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid)
    • (E-E )-3,3'-(1,4-Phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid)
    • [(3E)-3-[[4-[(E)-[7,7-Dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid
    • [3-[[4-[[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-ylidene]methyl]phenyl]methylene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methanesulfonic acid
    • {1,4-Phenylenebis[methanylylidene(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl-3-ylidene)]}dimethanesulfonic acid
    • 3,3''-(1,4-Phenylenedimethylidyne)bis[7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid]
    • Bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-, (1S-(1alpha(1R*,4R*),4beta))-
    • 90457-82-2

  • Applications

    Ecamsule (CAS 92761-26-7) is a UVA-absorbing compound widely used as an active UV filter in cosmetics and personal care products to provide UVA protection in sunscreens, moisturizers, and makeup formulations. Beyond cosmetic use, it may be incorporated as a UV-absorbing component in coatings, paints, and inks to enhance outdoor durability against light exposure. In the plastics and polymers sector, ecamsule can serve as a UV stabilizer to mitigate photo-oxidative degradation of formulated resins and packaging. In industrial coatings and outdoor materials, it is evaluated for inclusion to extend service life of surface finishes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.13
    methanol 3.21
    isopropanol 1.04
    water 0.01
    ethyl acetate 1.37
    n-propanol 1.51
    acetone 7.12
    n-butanol 0.77
    acetonitrile 2.49
    DMF 29.6
    toluene 0.34
    isobutanol 0.59
    1,4-dioxane 7.34
    methyl acetate 2.69
    THF 23.78
    2-butanone 5.09
    n-pentanol 0.63
    sec-butanol 0.57
    n-hexane 0.01
    ethylene glycol 0.65
    NMP 17.59
    cyclohexane 0.03
    DMSO 18.87
    n-butyl acetate 1.39
    n-octanol 0.51
    chloroform 8.07
    n-propyl acetate 1.5
    acetic acid 3.53
    dichloromethane 5.45
    cyclohexanone 6.09
    propylene glycol 0.89
    isopropyl acetate 0.83
    DMAc 25.71
    2-ethoxyethanol 4.09
    isopentanol 0.44
    n-heptane 0.01
    ethyl formate 2.05
    1,2-dichloroethane 2.22
    n-hexanol 0.52
    2-methoxyethanol 8.04
    isobutyl acetate 0.7
    tetrachloromethane 0.37
    n-pentyl acetate 1.35
    transcutol 4.55
    n-heptanol 0.53
    ethylbenzene 0.18
    MIBK 0.94
    2-propoxyethanol 5.83
    tert-butanol 0.58
    MTBE 0.36
    2-butoxyethanol 3.82
    propionic acid 1.62
    o-xylene 0.18
    formic acid 2.15
    diethyl ether 0.63
    m-xylene 0.16
    p-xylene 0.29
    chlorobenzene 0.75
    dimethyl carbonate 2.09
    n-octane 0.01
    formamide 4.67
    cyclopentanone 14.94
    2-pentanone 2.19
    anisole 0.96
    cyclopentyl methyl ether 1.24
    gamma-butyrolactone 11.86
    1-methoxy-2-propanol 4.4
    pyridine 6.69
    3-pentanone 1.61
    furfural 9.46
    n-dodecane 0.01
    diethylene glycol 3.95
    diisopropyl ether 0.08
    tert-amyl alcohol 0.39
    acetylacetone 3.91
    n-hexadecane 0.01
    acetophenone 1.7
    methyl propionate 2.01
    isopentyl acetate 1.01
    trichloroethylene 6.97
    n-nonanol 0.57
    cyclohexanol 0.43
    benzyl alcohol 1.21
    2-ethylhexanol 0.22
    isooctanol 0.33
    dipropyl ether 0.52
    1,2-dichlorobenzene 0.73
    ethyl lactate 1.15
    propylene carbonate 3.29
    n-methylformamide 8.63
    2-pentanol 0.25
    n-pentane 0.01
    1-propoxy-2-propanol 2.72
    1-methoxy-2-propyl acetate 2.33
    2-(2-methoxypropoxy) propanol 2.64
    mesitylene 0.09
    ε-caprolactone 4.16
    p-cymene 0.12
    epichlorohydrin 11.36
    1,1,1-trichloroethane 1.22
    2-aminoethanol 1.45
    morpholine-4-carbaldehyde 17.27
    sulfolane 12.96
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 3.02
    n-hexyl acetate 1.46
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 3.58
    sec-butyl acetate 0.61
    tert-butyl acetate 0.76
    decalin 0.01
    glycerin 1.91
    diglyme 7.37
    acrylic acid 2.02
    isopropyl myristate 0.45
    n-butyric acid 1.68
    acetyl acetate 1.16
    di(2-ethylhexyl) phthalate 0.82
    ethyl propionate 1.12
    nitromethane 11.86
    1,2-diethoxyethane 1.42
    benzonitrile 1.76
    trioctyl phosphate 0.51
    1-bromopropane 0.61
    gamma-valerolactone 23.53
    n-decanol 0.34
    triethyl phosphate 0.54
    4-methyl-2-pentanol 0.15
    propionitrile 1.88
    vinylene carbonate 4.11
    1,1,2-trichlorotrifluoroethane 8.41
    DMS 1.49
    cumene 0.1
    2-octanol 0.28
    2-hexanone 2.12
    octyl acetate 0.72
    limonene 0.15
    1,2-dimethoxyethane 9.55
    ethyl orthosilicate 0.44
    tributyl phosphate 0.55
    diacetone alcohol 1.67
    N,N-dimethylaniline 0.63
    acrylonitrile 3.67
    aniline 0.75
    1,3-propanediol 2.23
    bromobenzene 0.62
    dibromomethane 2.25
    1,1,2,2-tetrachloroethane 4.83
    2-methyl-cyclohexyl acetate 0.95
    tetrabutyl urea 1.49
    diisobutyl methanol 0.12
    2-phenylethanol 1.38
    styrene 0.25
    dioctyl adipate 0.98
    dimethyl sulfate 3.32
    ethyl butyrate 1.02
    methyl lactate 2.1
    butyl lactate 1.64
    diethyl carbonate 0.7
    propanediol butyl ether 2.48
    triethyl orthoformate 0.84
    p-tert-butyltoluene 0.11
    methyl 4-tert-butylbenzoate 1.65
    morpholine 8.9
    tert-butylamine 0.16
    n-dodecanol 0.2
    dimethoxymethane 8.67
    ethylene carbonate 2.93
    cyrene 4.03
    2-ethoxyethyl acetate 2.57
    2-ethylhexyl acetate 0.74
    1,2,4-trichlorobenzene 1.08
    4-methylpyridine 3.25
    dibutyl ether 0.4
    2,6-dimethyl-4-heptanol 0.12
    DEF 3.31
    dimethyl isosorbide 5.06
    tetrachloroethylene 2.52
    eugenol 2.42
    triacetin 1.74
    span 80 1.97
    1,4-butanediol 0.86
    1,1-dichloroethane 1.5
    2-methyl-1-pentanol 0.32
    methyl formate 5.67
    2-methyl-1-butanol 0.38
    n-decane 0.02
    butyronitrile 1.45
    3,7-dimethyl-1-octanol 0.28
    1-chlorooctane 0.15
    1-chlorotetradecane 0.05
    n-nonane 0.02
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.01
    cyclopentanol 1.29
    tetrahydropyran 2.88
    tert-amyl methyl ether 0.28
    2,5,8-trioxanonane 4.57
    1-hexene 0.09
    2-isopropoxyethanol 1.82
    2,2,2-trifluoroethanol 1.61
    methyl butyrate 1.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction