Dodecylphosphate

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  • Identifiers

    CAS number
    12751-23-4

    Molecular formula
    C12H25O4P-2

    SMILES
    CCCCCCCCCCCCOP(=O)([O-])[O-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Waxy 45.83%
    Odorless 39.98%
    Fatty 36.08%
    Oily 33.42%
    Fresh 29.58%
    Citrus 28.74%
    Sweet 24.48%
    Floral 23.48%
    Clean 21.98%
    Balsamic 21.97%

     

    Flavor
    Fatty 40.87%
    Waxy 36.49%
    Odorless 33.5%
    Mild 32.8%
    Bland 28.98%
    Fat 24.68%
    Faint 24.46%
    Oily 24.37%
    Bay oil 23.33%
    Slightly waxy 23.32%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    4.92 (weak acid)

    Molecular weight
    264.3 g/mol

    Flash point

    • 193.07 ˚C est.

  • Synonyms

    • dodecyl phosphate
    • dodecylphosphate
    • 12751-23-4
    • dodecanol phosphate
    • FAP12
    • FAP-12
    • RefChem:135531
    • DTXSID9044530
    • Phosphoric acid, dodecyl ester
    • Mono--odecyl phosphate
    • GTPL4031
    • C12H25O4P-2
    • DB-007446
    • Q27077092
    • 12751-23-4

  • Applications

    Dodecylphosphate (CAS 12751-23-4) is used primarily as a surfactant and emulsifier in household and industrial cleaning formulations, where its alkyl phosphate group helps reduce surface tension, improve wetting, and facilitate dispersion. It is also employed in cosmetics and personal care as a surfactant/emulsifier system to aid formulation stability and texture. In coatings and inks, it acts as a surfactant and processing aid to improve leveling, compatibility, and pigment dispersion. In polymer and plastics processing, it can function as a processing aid or stabilizer, assisting filler dispersion and compatibility in polymer blends. Additionally, it may be used as an agricultural adjuvant to improve spray distribution and adhesion of agrochemical formulations. Overall, applications center on surfactant/emulsifier and processing-aid roles across multiple industries, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 168.39
    methanol 210.31
    isopropanol 139.15
    water 0.19
    ethyl acetate 90.93
    n-propanol 134.57
    acetone 191.37
    n-butanol 102.23
    acetonitrile 60.25
    DMF 454.98
    toluene 60.14
    isobutanol 89.13
    1,4-dioxane 184.11
    methyl acetate 83.21
    THF 539.73
    2-butanone 137.46
    n-pentanol 94.48
    sec-butanol 107.39
    n-hexane 11.63
    ethylene glycol 40.74
    NMP 490.1
    cyclohexane 26.36
    DMSO 669.26
    n-butyl acetate 114.43
    n-octanol 64.07
    chloroform 253.59
    n-propyl acetate 102.07
    acetic acid 111.08
    dichloromethane 255.04
    cyclohexanone 314.35
    propylene glycol 86.73
    isopropyl acetate 94.49
    DMAc 328.33
    2-ethoxyethanol 182.61
    isopentanol 90.94
    n-heptane 8.82
    ethyl formate 65.27
    1,2-dichloroethane 249.62
    n-hexanol 97.02
    2-methoxyethanol 270.88
    isobutyl acetate 68.91
    tetrachloromethane 40.34
    n-pentyl acetate 118.36
    transcutol 426.06
    n-heptanol 67.08
    ethylbenzene 35.33
    MIBK 115.51
    2-propoxyethanol 202.54
    tert-butanol 184.65
    MTBE 123.45
    2-butoxyethanol 146.5
    propionic acid 102.89
    o-xylene 51.89
    formic acid 53.71
    diethyl ether 96.24
    m-xylene 54.13
    p-xylene 46.08
    chlorobenzene 87.81
    dimethyl carbonate 48.13
    n-octane 5.74
    formamide 124.11
    cyclopentanone 428.3
    2-pentanone 144.03
    anisole 86.49
    cyclopentyl methyl ether 198.32
    gamma-butyrolactone 363.74
    1-methoxy-2-propanol 237.57
    pyridine 170.87
    3-pentanone 96.25
    furfural 292.53
    n-dodecane 4.36
    diethylene glycol 136.85
    diisopropyl ether 42.59
    tert-amyl alcohol 150.18
    acetylacetone 196.24
    n-hexadecane 5.13
    acetophenone 111.75
    methyl propionate 92.55
    isopentyl acetate 118.45
    trichloroethylene 358.68
    n-nonanol 59.44
    cyclohexanol 125.98
    benzyl alcohol 87.75
    2-ethylhexanol 58.91
    isooctanol 57.69
    dipropyl ether 64.26
    1,2-dichlorobenzene 103.88
    ethyl lactate 64.53
    propylene carbonate 170.25
    n-methylformamide 167.96
    2-pentanol 77.48
    n-pentane 11.29
    1-propoxy-2-propanol 157.15
    1-methoxy-2-propyl acetate 135.05
    2-(2-methoxypropoxy) propanol 126.97
    mesitylene 41.85
    ε-caprolactone 229.8
    p-cymene 31.79
    epichlorohydrin 362.02
    1,1,1-trichloroethane 151.13
    2-aminoethanol 115.92
    morpholine-4-carbaldehyde 335.01
    sulfolane 675.43
    2,2,4-trimethylpentane 8.26
    2-methyltetrahydrofuran 264.6
    n-hexyl acetate 130.83
    isooctane 7.0
    2-(2-butoxyethoxy)ethanol 189.19
    sec-butyl acetate 74.64
    tert-butyl acetate 148.87
    decalin 11.94
    glycerin 115.75
    diglyme 281.41
    acrylic acid 86.26
    isopropyl myristate 50.58
    n-butyric acid 136.5
    acetyl acetate 67.97
    di(2-ethylhexyl) phthalate 58.67
    ethyl propionate 72.24
    nitromethane 188.51
    1,2-diethoxyethane 128.39
    benzonitrile 97.63
    trioctyl phosphate 44.58
    1-bromopropane 112.06
    gamma-valerolactone 460.63
    n-decanol 43.86
    triethyl phosphate 46.77
    4-methyl-2-pentanol 52.5
    propionitrile 64.33
    vinylene carbonate 127.66
    1,1,2-trichlorotrifluoroethane 269.46
    DMS 90.68
    cumene 28.43
    2-octanol 52.57
    2-hexanone 118.1
    octyl acetate 66.1
    limonene 49.99
    1,2-dimethoxyethane 223.4
    ethyl orthosilicate 47.88
    tributyl phosphate 50.17
    diacetone alcohol 200.76
    N,N-dimethylaniline 73.06
    acrylonitrile 87.18
    aniline 89.73
    1,3-propanediol 137.03
    bromobenzene 91.77
    dibromomethane 182.29
    1,1,2,2-tetrachloroethane 358.45
    2-methyl-cyclohexyl acetate 96.08
    tetrabutyl urea 77.53
    diisobutyl methanol 43.42
    2-phenylethanol 94.95
    styrene 44.39
    dioctyl adipate 80.73
    dimethyl sulfate 122.55
    ethyl butyrate 79.15
    methyl lactate 83.05
    butyl lactate 112.53
    diethyl carbonate 47.5
    propanediol butyl ether 155.29
    triethyl orthoformate 64.19
    p-tert-butyltoluene 35.34
    methyl 4-tert-butylbenzoate 130.11
    morpholine 299.68
    tert-butylamine 111.7
    n-dodecanol 31.93
    dimethoxymethane 201.1
    ethylene carbonate 109.3
    cyrene 139.8
    2-ethoxyethyl acetate 143.43
    2-ethylhexyl acetate 90.46
    1,2,4-trichlorobenzene 130.81
    4-methylpyridine 162.64
    dibutyl ether 58.25
    2,6-dimethyl-4-heptanol 43.42
    DEF 169.63
    dimethyl isosorbide 237.28
    tetrachloroethylene 219.05
    eugenol 124.99
    triacetin 139.53
    span 80 139.1
    1,4-butanediol 62.21
    1,1-dichloroethane 153.47
    2-methyl-1-pentanol 79.41
    methyl formate 87.1
    2-methyl-1-butanol 78.56
    n-decane 7.67
    butyronitrile 74.27
    3,7-dimethyl-1-octanol 59.88
    1-chlorooctane 38.09
    1-chlorotetradecane 14.89
    n-nonane 7.09
    undecane 5.6
    tert-butylcyclohexane 10.44
    cyclooctane 8.93
    cyclopentanol 179.33
    tetrahydropyran 210.47
    tert-amyl methyl ether 101.45
    2,5,8-trioxanonane 205.51
    1-hexene 38.6
    2-isopropoxyethanol 129.78
    2,2,2-trifluoroethanol 49.31
    methyl butyrate 102.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction