Dodecylhexadecyltrimonium Chloride

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  • Identifiers

    CAS number
    103807-18-7

    Molecular formula
    C31H66ClN

    SMILES
    CCCCCCCCCCCCCCC(CCCCCCCCCCCC)C[N+](C)(C)C.[Cl-]

    Safety labels

  • Odor profile

    Fragrance
    Waxy 79.7%
    Fatty 43.34%
    Oily 36.3%
    Odorless 23.54%
    Fishy 20.0%
    Meaty 17.95%
    Savory 16.61%
    Burnt 16.35%
    Balsamic 15.95%
    Clean 15.07%

     

    Flavor
    Waxy 34.46%
    Alkane 32.77%
    Bland 30.73%
    Mild 24.81%
    Delicate 21.75%
    Slightly waxy 20.84%
    Faint 19.44%
    Diterpene 19.29%
    Oriental 19.0%
    Low 18.96%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.85 (weak base)

    Molecular weight
    488.3 g/mol

    Flash point

    • 157.07 ˚C est.

  • Synonyms

    • Dodecylhexadecyltrimonium chloride
    • Tetrasal
    • Quartamin 280GP
    • 103807-18-7
    • UNII-75728NH7QU
    • 75728NH7QU
    • (2-Dodecylhexadecyl)trimethylammonium chloride
    • N-(2-dodecyl)hexadecyl-N,N,N-trimethylammonium chloride
    • 1-Hexadecanaminium, 2-dodecyl-N,N,N-trimethyl-, chloride
    • 1-Hexadecanaminium, 2-dodecyl-N,N,N-trimethyl-, chloride (1:1)
    • RefChem:135525
    • (+-)-DODECYLHEXADECYLTRIMONIUM CHLORIDE
    • DODECYLHEXADECYLTRIMONIUM CHLORIDE [INCI]
    • DODECYLHEXADECYLTRIMONIUM CHLORIDE, (+-)-
    • (+/-)-Dodecylhexadecyltrimonium chloride
    • Dodecylhexadecyltrimonium chloride, (+/-)-
    • 2-dodecylhexadecyl(trimethyl)azanium;chloride
    • SCHEMBL593800
    • DTXSID10908609
    • CYZIPMMNONORGD-UHFFFAOYSA-M
    • 2-Dodecyl-N,N,N-trimethylhexadecan-1-aminium chloride
    • Q27266354
    • 103807-18-7

  • Applications

    Dodecylhexadecyltrimonium chloride (CAS 103807-18-7) is a cationic quaternary ammonium compound used as a surfactant and conditioning agent in a range of formulations. In cosmetics and personal care, it functions as a conditioning agent for hair and skin, reduces static, and improves the feel of the product. In household cleaners and fabric care, it acts as a surfactant and can be used as a fabric softener additive and anti-static booster for laundry formulations. In textile finishing and polymer processing, it serves as a finishing agent, antistatic additive, and lubricating aid to improve handling and finish. In coatings and inks, it is used as an emulsifier and wetting agent to enhance pigment dispersion and substrate wetting. In polymers and plastics processing, it can function as a surface-treatment or processing-aid additive to improve flow and slip. It may also be used as an antimicrobial/quaternary ammonium additive in some cleaners, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 60.96
    methanol 32.06
    isopropanol 89.6
    water 0.11
    ethyl acetate 833.4
    n-propanol 125.53
    acetone 382.27
    n-butanol 190.25
    acetonitrile 78.43
    DMF 319.01
    toluene 467.48
    isobutanol 179.1
    1,4-dioxane 724.22
    methyl acetate 391.28
    THF 1633.63
    2-butanone 585.75
    n-pentanol 158.18
    sec-butanol 194.0
    n-hexane 294.11
    ethylene glycol 4.71
    NMP 1143.77
    cyclohexane 1245.47
    DMSO 342.6
    n-butyl acetate 1064.41
    n-octanol 292.21
    chloroform 1934.27
    n-propyl acetate 863.52
    acetic acid 159.45
    dichloromethane 1639.0
    cyclohexanone 1851.31
    propylene glycol 18.02
    isopropyl acetate 1029.68
    DMAc 783.21
    2-ethoxyethanol 226.39
    isopentanol 286.31
    n-heptane 593.87
    ethyl formate 257.16
    1,2-dichloroethane 1073.58
    n-hexanol 205.64
    2-methoxyethanol 184.16
    isobutyl acetate 798.84
    tetrachloromethane 885.38
    n-pentyl acetate 1409.37
    transcutol 1272.29
    n-heptanol 297.82
    ethylbenzene 300.67
    MIBK 848.41
    2-propoxyethanol 321.43
    tert-butanol 237.68
    MTBE 778.03
    2-butoxyethanol 499.81
    propionic acid 212.03
    o-xylene 436.99
    formic acid 19.61
    diethyl ether 648.87
    m-xylene 387.87
    p-xylene 463.09
    chlorobenzene 559.14
    dimethyl carbonate 211.34
    n-octane 212.17
    formamide 32.14
    cyclopentanone 1509.05
    2-pentanone 781.04
    anisole 411.34
    cyclopentyl methyl ether 1745.54
    gamma-butyrolactone 1265.27
    1-methoxy-2-propanol 282.78
    pyridine 562.14
    3-pentanone 820.51
    furfural 621.03
    n-dodecane 67.43
    diethylene glycol 82.56
    diisopropyl ether 618.99
    tert-amyl alcohol 410.14
    acetylacetone 895.34
    n-hexadecane 84.46
    acetophenone 510.92
    methyl propionate 592.69
    isopentyl acetate 1210.87
    trichloroethylene 1750.51
    n-nonanol 324.64
    cyclohexanol 667.01
    benzyl alcohol 186.94
    2-ethylhexanol 407.77
    isooctanol 401.88
    dipropyl ether 1337.21
    1,2-dichlorobenzene 628.11
    ethyl lactate 266.47
    propylene carbonate 927.91
    n-methylformamide 103.89
    2-pentanol 257.33
    n-pentane 225.02
    1-propoxy-2-propanol 544.45
    1-methoxy-2-propyl acetate 954.19
    2-(2-methoxypropoxy) propanol 385.39
    mesitylene 366.79
    ε-caprolactone 1604.44
    p-cymene 430.04
    epichlorohydrin 1174.21
    1,1,1-trichloroethane 1938.67
    2-aminoethanol 22.58
    morpholine-4-carbaldehyde 749.85
    sulfolane 1816.22
    2,2,4-trimethylpentane 255.63
    2-methyltetrahydrofuran 1628.74
    n-hexyl acetate 1156.66
    isooctane 157.78
    2-(2-butoxyethoxy)ethanol 510.26
    sec-butyl acetate 961.68
    tert-butyl acetate 1523.52
    decalin 367.78
    glycerin 31.66
    diglyme 1478.8
    acrylic acid 118.28
    isopropyl myristate 480.33
    n-butyric acid 567.81
    acetyl acetate 598.39
    di(2-ethylhexyl) phthalate 248.25
    ethyl propionate 849.03
    nitromethane 288.65
    1,2-diethoxyethane 1059.69
    benzonitrile 242.43
    trioctyl phosphate 240.28
    1-bromopropane 922.64
    gamma-valerolactone 1463.04
    n-decanol 210.75
    triethyl phosphate 654.41
    4-methyl-2-pentanol 254.64
    propionitrile 157.56
    vinylene carbonate 585.98
    1,1,2-trichlorotrifluoroethane 822.47
    DMS 522.48
    cumene 265.23
    2-octanol 307.43
    2-hexanone 716.18
    octyl acetate 494.81
    limonene 923.59
    1,2-dimethoxyethane 751.37
    ethyl orthosilicate 738.69
    tributyl phosphate 313.59
    diacetone alcohol 801.71
    N,N-dimethylaniline 374.28
    acrylonitrile 115.42
    aniline 295.51
    1,3-propanediol 69.12
    bromobenzene 762.58
    dibromomethane 1193.04
    1,1,2,2-tetrachloroethane 1997.5
    2-methyl-cyclohexyl acetate 964.04
    tetrabutyl urea 431.94
    diisobutyl methanol 457.17
    2-phenylethanol 203.72
    styrene 299.04
    dioctyl adipate 578.57
    dimethyl sulfate 454.08
    ethyl butyrate 1273.14
    methyl lactate 180.14
    butyl lactate 673.79
    diethyl carbonate 640.42
    propanediol butyl ether 254.45
    triethyl orthoformate 1215.56
    p-tert-butyltoluene 432.07
    methyl 4-tert-butylbenzoate 780.75
    morpholine 820.66
    tert-butylamine 230.92
    n-dodecanol 148.26
    dimethoxymethane 428.93
    ethylene carbonate 660.48
    cyrene 384.08
    2-ethoxyethyl acetate 1151.11
    2-ethylhexyl acetate 1218.08
    1,2,4-trichlorobenzene 776.26
    4-methylpyridine 623.4
    dibutyl ether 1086.68
    2,6-dimethyl-4-heptanol 457.17
    DEF 971.96
    dimethyl isosorbide 909.6
    tetrachloroethylene 1362.06
    eugenol 389.88
    triacetin 1052.07
    span 80 421.41
    1,4-butanediol 32.76
    1,1-dichloroethane 1081.12
    2-methyl-1-pentanol 253.8
    methyl formate 103.73
    2-methyl-1-butanol 285.8
    n-decane 192.37
    butyronitrile 242.46
    3,7-dimethyl-1-octanol 415.61
    1-chlorooctane 570.54
    1-chlorotetradecane 162.7
    n-nonane 212.06
    undecane 103.71
    tert-butylcyclohexane 295.45
    cyclooctane 499.74
    cyclopentanol 494.22
    tetrahydropyran 1573.97
    tert-amyl methyl ether 914.96
    2,5,8-trioxanonane 658.82
    1-hexene 390.95
    2-isopropoxyethanol 287.83
    2,2,2-trifluoroethanol 111.22
    methyl butyrate 1018.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction