Dodecylhexadecanol

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  • Identifiers

    CAS number
    72388-18-2

    Molecular formula
    C28H58O

    SMILES
    CCCCCCCCCCCCCCC(CCCCCCCCCCCC)CO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 76.37%
    Fatty 52.11%
    Oily 44.28%
    Odorless 28.13%
    Fishy 20.36%
    Meaty 19.28%
    Clean 19.02%
    Balsamic 18.12%
    Savory 17.23%
    Orris 16.29%

     

    Flavor
    Waxy 49.76%
    Alkane 37.62%
    Mild 32.05%
    Bland 30.86%
    Faint 24.14%
    Slightly waxy 23.18%
    Delicate 22.8%
    Fatty 22.23%
    Wax 21.0%
    Incense 20.9%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    13.5

    pKa est.
    8.17 (weak base)

    Molecular weight
    410.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    516°C

    Flash point

    • 215.98 ˚C est.

  • Synonyms

    • 2-Dodecylhexadecan-1-ol
    • 72388-18-2
    • 2-dodecyl-1-hexadecanol
    • dodecylhexadecanol
    • 1-Hexadecanol, 2-dodecyl-
    • EINECS 276-627-0
    • XO7ECC3647
    • GUERBET C28
    • ISOFOL 28 ALCOHOL
    • (+/)-DODECYLHEXADECANOL
    • DTXSID40888147
    • EC 276-627-0
    • RefChem:590337
    • DODECYLHEXADECANOL [INCI]
    • DTXCID001027429
    • DODECYLHEXADECANOL, (+-)-
    • 1-Hexadecanol,2-dodecyl-
    • 2-dodecylhexadecyl alcohol
    • MFCD27665210
    • UNII-XO7ECC3647
    • 2-dodecylhexadecanol
    • 2-Dodecylcetylalkohol
    • SCHEMBL810157
    • SCHEMBL28343554
    • DEMBLPGWNXUBIQ-UHFFFAOYSA-N
    • DODECYLHEXADECANOL, (+/-)-
    • BS-44122
    • DA-26292
    • D5322
    • NS00004568
    • Q27293936
    • 72388-18-2

  • Applications

    Dodecylhexadecanol (CAS 72388-18-2) is a high-molecular-weight fatty alcohol that is commonly used as an emollient and thickener in cosmetics and personal care formulations; it serves as a waxy additive and conditioning agent in household and cleaning products; it acts as a processing aid and lubricant in industrial manufacturing and polymer formulations; it is a precursor for nonionic surfactants (fatty alcohol ethoxylates) used in cleaners and paints; it can function as a wax modifier or slip agent in coatings and inks; and it may be used as a solvent or fragrance carrier in fragrance formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.57
    methanol 5.81
    isopropanol 8.96
    water 0.02
    ethyl acetate 114.96
    n-propanol 12.53
    acetone 52.56
    n-butanol 20.17
    acetonitrile 11.45
    DMF 72.88
    toluene 38.79
    isobutanol 16.65
    1,4-dioxane 120.39
    methyl acetate 57.26
    THF 384.25
    2-butanone 84.23
    n-pentanol 15.82
    sec-butanol 18.99
    n-hexane 20.13
    ethylene glycol 0.63
    NMP 320.01
    cyclohexane 134.01
    DMSO 118.86
    n-butyl acetate 199.52
    n-octanol 48.78
    chloroform 355.83
    n-propyl acetate 159.93
    acetic acid 24.14
    dichloromethane 316.99
    cyclohexanone 377.86
    propylene glycol 2.48
    isopropyl acetate 152.9
    DMAc 193.83
    2-ethoxyethanol 39.04
    isopentanol 34.21
    n-heptane 47.05
    ethyl formate 39.95
    1,2-dichloroethane 206.8
    n-hexanol 21.76
    2-methoxyethanol 36.3
    isobutyl acetate 128.45
    tetrachloromethane 134.84
    n-pentyl acetate 357.59
    transcutol 407.27
    n-heptanol 42.08
    ethylbenzene 38.75
    MIBK 144.35
    2-propoxyethanol 55.31
    tert-butanol 32.63
    MTBE 99.66
    2-butoxyethanol 109.38
    propionic acid 29.08
    o-xylene 50.19
    formic acid 3.5
    diethyl ether 61.71
    m-xylene 40.85
    p-xylene 59.77
    chlorobenzene 86.69
    dimethyl carbonate 31.97
    n-octane 20.96
    formamide 7.66
    cyclopentanone 351.61
    2-pentanone 109.66
    anisole 84.0
    cyclopentyl methyl ether 245.63
    gamma-butyrolactone 313.22
    1-methoxy-2-propanol 52.6
    pyridine 105.32
    3-pentanone 106.01
    furfural 186.01
    n-dodecane 8.3
    diethylene glycol 15.25
    diisopropyl ether 63.78
    tert-amyl alcohol 51.34
    acetylacetone 172.04
    n-hexadecane 10.6
    acetophenone 124.76
    methyl propionate 78.69
    isopentyl acetate 240.53
    trichloroethylene 373.33
    n-nonanol 56.21
    cyclohexanol 74.91
    benzyl alcohol 31.75
    2-ethylhexanol 51.58
    isooctanol 61.94
    dipropyl ether 194.19
    1,2-dichlorobenzene 135.03
    ethyl lactate 53.14
    propylene carbonate 218.93
    n-methylformamide 20.07
    2-pentanol 23.07
    n-pentane 13.37
    1-propoxy-2-propanol 102.34
    1-methoxy-2-propyl acetate 206.05
    2-(2-methoxypropoxy) propanol 116.53
    mesitylene 45.97
    ε-caprolactone 350.75
    p-cymene 66.82
    epichlorohydrin 286.63
    1,1,1-trichloroethane 346.6
    2-aminoethanol 3.15
    morpholine-4-carbaldehyde 186.6
    sulfolane 644.93
    2,2,4-trimethylpentane 23.59
    2-methyltetrahydrofuran 285.97
    n-hexyl acetate 269.13
    isooctane 13.98
    2-(2-butoxyethoxy)ethanol 140.42
    sec-butyl acetate 165.34
    tert-butyl acetate 289.7
    decalin 41.3
    glycerin 5.78
    diglyme 428.23
    acrylic acid 17.98
    isopropyl myristate 105.81
    n-butyric acid 90.56
    acetyl acetate 98.58
    di(2-ethylhexyl) phthalate 61.7
    ethyl propionate 152.18
    nitromethane 66.64
    1,2-diethoxyethane 240.99
    benzonitrile 50.18
    trioctyl phosphate 53.03
    1-bromopropane 131.38
    gamma-valerolactone 425.88
    n-decanol 33.7
    triethyl phosphate 158.41
    4-methyl-2-pentanol 28.78
    propionitrile 20.22
    vinylene carbonate 133.64
    1,1,2-trichlorotrifluoroethane 197.48
    DMS 108.3
    cumene 38.0
    2-octanol 50.03
    2-hexanone 124.32
    octyl acetate 108.32
    limonene 132.37
    1,2-dimethoxyethane 181.48
    ethyl orthosilicate 166.15
    tributyl phosphate 76.76
    diacetone alcohol 178.74
    N,N-dimethylaniline 75.34
    acrylonitrile 17.92
    aniline 36.34
    1,3-propanediol 10.38
    bromobenzene 121.47
    dibromomethane 213.98
    1,1,2,2-tetrachloroethane 422.09
    2-methyl-cyclohexyl acetate 230.66
    tetrabutyl urea 117.99
    diisobutyl methanol 69.26
    2-phenylethanol 38.22
    styrene 40.84
    dioctyl adipate 167.25
    dimethyl sulfate 100.27
    ethyl butyrate 269.1
    methyl lactate 33.42
    butyl lactate 166.0
    diethyl carbonate 137.49
    propanediol butyl ether 67.79
    triethyl orthoformate 266.11
    p-tert-butyltoluene 66.08
    methyl 4-tert-butylbenzoate 219.62
    morpholine 144.97
    tert-butylamine 28.15
    n-dodecanol 23.32
    dimethoxymethane 68.3
    ethylene carbonate 137.93
    cyrene 120.03
    2-ethoxyethyl acetate 290.85
    2-ethylhexyl acetate 223.49
    1,2,4-trichlorobenzene 173.82
    4-methylpyridine 104.93
    dibutyl ether 206.27
    2,6-dimethyl-4-heptanol 69.26
    DEF 163.38
    dimethyl isosorbide 340.55
    tetrachloroethylene 259.34
    eugenol 126.08
    triacetin 274.9
    span 80 113.21
    1,4-butanediol 4.3
    1,1-dichloroethane 162.85
    2-methyl-1-pentanol 29.62
    methyl formate 18.09
    2-methyl-1-butanol 30.43
    n-decane 23.35
    butyronitrile 31.64
    3,7-dimethyl-1-octanol 70.81
    1-chlorooctane 91.27
    1-chlorotetradecane 25.15
    n-nonane 23.58
    undecane 12.68
    tert-butylcyclohexane 30.97
    cyclooctane 41.33
    cyclopentanol 68.1
    tetrahydropyran 232.76
    tert-amyl methyl ether 120.84
    2,5,8-trioxanonane 215.65
    1-hexene 34.06
    2-isopropoxyethanol 45.05
    2,2,2-trifluoroethanol 18.37
    methyl butyrate 206.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction