Dodecyldimethylamine oxide

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  • Identifiers

    CAS number
    1643-20-5

    Molecular formula
    C14H31NO

    SMILES
    CCCCCCCCCCCC[N+](C)(C)[O-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 57.6%
    Fatty 39.3%
    Oily 37.07%
    Floral 34.77%
    Fresh 31.19%
    Woody 28.93%
    Sweet 27.66%
    Citrus 25.71%
    Clean 25.7%
    Fruity 24.66%

     

    Flavor
    Bland 28.18%
    Mild 23.95%
    Waxy 22.4%
    Delicate 21.71%
    Slightly waxy 20.6%
    Skunky 20.32%
    Leathery 19.83%
    Diterpene 19.56%
    Bloody 19.24%
    Glue 19.19%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    6.3 (neutral)

    Molecular weight
    229.4 g/mol

    Melting point expt.

    • 266 to 268 °F (NTP, 1992)
    • 130.5 °C

    Flash point

    • -328.05 ˚C est.

    Solubility expt.

    • In water, 190,000 mg/L at 25 °C

  • Synonyms

    • 1643-20-5
    • Lauramine oxide
    • Lauryldimethylamine oxide
    • 1-Dodecanamine, N,N-dimethyl-, N-oxide
    • LDAO
    • Dodecyldimethylamine oxide
    • Lauryldimethylamine N-oxide
    • Ammonyx AO
    • Ammonyx LO
    • Empigen OB
    • Dimethyldodecylamine oxide
    • Dodecyldimethylamine N-oxide
    • Aromox DMCD
    • Conco XAL
    • Dimethylaurylamine oxide
    • Dimethyldodecylamine N-oxide
    • dodecyl(dimethyl)amine oxide
    • DDNO
    • n-Dodecyldimethylamine oxide
    • Aromox dmmc-W
    • Amonyx AO
    • Dimethyllaurylamine oxide
    • N,N-Dimethyldodecylamine-N-oxide
    • Refan
    • Laurylamine oxide
    • Lauryl dimethyl amine oxide
    • N-Lauryl-N,N-dimethylamine oxide
    • N-Lauryldimethylamine N-oxide
    • NCI-C55129
    • Oxyde de dimethyllaurylamine
    • 4F6FC4MI8W
    • N,N-Dimethyl-1-dodecanamine-N-oxide
    • N,N-Dimethyl-dodecylaminoxid
    • Dodecylamine, N,N-dimethyl-, N-oxide
    • 1-Dodecanamine, N,N-dimethl-, N-oxide
    • DTXSID1020514
    • CHEBI:131762
    • StepSept PB-50
    • RefChem:57825
    • DTXCID8042
    • N,N-dimethyldodecyclamine N-oxide
    • N-dodecyl-N,N-dimethylamine N-oxide
    • 216-700-6
    • DDAO
    • N,N-dimethyldodecan-1-amine oxide
    • N,N-Dimethyldodecylamine N-oxide
    • N,N-Dimethyl-1-dodecylamine N-oxide
    • lauryl dimethylamine oxide
    • LAURYL DIMETHYLAMINE-N-OXIDE
    • N,N-Dimethyldodecylamine oxide
    • MFCD00002049
    • amine oxide, dodecyl(dimethyl)-
    • CHEMBL1233973
    • N,N-dimethyldodecan-1-amine N-oxide
    • Refan [Russian]
    • HSDB 5451
    • EINECS 216-700-6
    • N,N-Dimethyl-dodecylaminoxid [Czech]
    • Oxyde de dimethyllaurylamine [French]
    • UNII-4F6FC4MI8W
    • BRN 1769927
    • Cyclomox L
    • Rhodamox L
    • Softamine L
    • Genaminox LA
    • Schercamox DML
    • Rhodamox LO
    • Oxamin LO
    • Emcol L
    • Incromine oxide L
    • Emcol LO
    • Unisafe A-LM
    • Amphitol 20N
    • Barlox 12i
    • Rewominox L 408
    • Ammonyx DMCD 40
    • Admox 12
    • Aromox DM 12D
    • Aromox DM 12W
    • Oxidet DM 20
    • EUROXIDE LO
    • Aromox DM 12D-W
    • Emal 20N
    • imethylauroylamine oxide
    • Atlas CD 413
    • Tomah AO 728
    • Aromox DM 12DW(C)
    • Ammonyx C10 Amine Oxide
    • lauryldimethylamine-N-oxide
    • EC 216-700-6
    • n,n-dimethyl lauramine oxide
    • SCHEMBL27337
    • LAURAMINE OXIDE [II]
    • 4-04-00-00798 (Beilstein Handbook Reference)
    • LAURYLDIMETHYLAMINEOXIDE
    • LAURAMINE OXIDE [HSDB]
    • orb1306500
    • 101CG
    • BDBM50327308
    • AKOS015904034
    • AKOS040744734
    • N,N-dimethyl-1-dodecanamine, n-oxide
    • DB04147
    • DD12118
    • FD46143
    • HY-W127785
    • NCGC00164286-01
    • SY073421
    • CS-0185955
    • L0361
    • NS00001592
    • D78505
    • 1-Dodecanamine, N,N-dimethyl-, N-oxide (9CI)
    • LDAO, N,N-dimethyldodecylamine N-oxide, powder
    • Dodecylamine, N,N-dimethyl-, N-oxide (6CI,8CI)
    • F837460
    • J-521637
    • Q6501952
    • N,N-Dimethyldodecylamine N-Oxide (ca. 30% in Water)
    • N,N-Dimethyldodecylamine N-oxide, >=99% (titration)
    • N,N-Dimethyldodecylamine N-oxide solution ~30% in H2O
    • N,N-Dimethyl-1-dodecylamine N-oxide, 30% aqueous solution
    • N,N-Dimethyldodecylamine N-oxide - 30% solution in water
    • N,N-Dimethyldodecylamine N-oxide, BioXtra, >=99.0% (NT)
    • N,N-Dimethyldodecan-1-amine Oxide, 30wt.% solution in H2O
    • 1643-20-5

  • Applications

    Dodecyldimethylamine oxide is a nonionic surfactant that is commonly used as a surfactant, emulsifier and foaming/wetting agent in a range of formulations. In cosmetics and personal care, it helps stabilize emulsions and improve cleansing performance in products such as shampoos, body washes and facial cleansers. In household cleaning products, it serves as a mild surfactant and foaming agent. In industrial manufacturing, it functions as a wetting agent, emulsifier and stabilizer for polymer and pigment suspensions and for coating and textile formulations. In coatings and inks, it improves substrate wetting, dispersion and leveling. In polymer processing, it can act as a processing aid or emulsifier for latex and other polymer dispersions. It is also commonly evaluated as a surfactant or adjuvant in agrochemical formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 666.82
    methanol 723.71
    isopropanol 610.8
    water 0.37
    ethyl acetate 981.2
    n-propanol 691.25
    acetone 714.63
    n-butanol 642.98
    acetonitrile 448.19
    DMF 576.71
    toluene 509.16
    isobutanol 588.29
    1,4-dioxane 1255.36
    methyl acetate 683.56
    THF 1469.26
    2-butanone 764.04
    n-pentanol 457.76
    sec-butanol 649.09
    n-hexane 475.75
    ethylene glycol 98.67
    NMP 872.18
    cyclohexane 1050.98
    DMSO 629.33
    n-butyl acetate 873.24
    n-octanol 302.79
    chloroform 3089.6
    n-propyl acetate 756.57
    acetic acid 677.45
    dichloromethane 2335.96
    cyclohexanone 1574.06
    propylene glycol 213.63
    isopropyl acetate 659.5
    DMAc 660.99
    2-ethoxyethanol 617.07
    isopentanol 579.15
    n-heptane 363.07
    ethyl formate 487.29
    1,2-dichloroethane 1336.55
    n-hexanol 575.04
    2-methoxyethanol 798.26
    isobutyl acetate 539.15
    tetrachloromethane 824.6
    n-pentyl acetate 628.45
    transcutol 2095.36
    n-heptanol 287.09
    ethylbenzene 349.54
    MIBK 459.31
    2-propoxyethanol 786.24
    tert-butanol 789.3
    MTBE 827.7
    2-butoxyethanol 508.33
    propionic acid 627.86
    o-xylene 414.42
    formic acid 168.19
    diethyl ether 935.32
    m-xylene 374.97
    p-xylene 465.29
    chlorobenzene 724.54
    dimethyl carbonate 166.81
    n-octane 105.62
    formamide 187.3
    cyclopentanone 1126.28
    2-pentanone 663.78
    anisole 458.13
    cyclopentyl methyl ether 1080.68
    gamma-butyrolactone 1159.31
    1-methoxy-2-propanol 680.26
    pyridine 966.69
    3-pentanone 645.98
    furfural 960.07
    n-dodecane 53.61
    diethylene glycol 450.2
    diisopropyl ether 351.0
    tert-amyl alcohol 736.86
    acetylacetone 681.69
    n-hexadecane 63.68
    acetophenone 463.59
    methyl propionate 612.27
    isopentyl acetate 745.22
    trichloroethylene 2295.22
    n-nonanol 278.37
    cyclohexanol 1076.19
    benzyl alcohol 359.92
    2-ethylhexanol 513.2
    isooctanol 273.6
    dipropyl ether 768.25
    1,2-dichlorobenzene 783.38
    ethyl lactate 342.35
    propylene carbonate 810.17
    n-methylformamide 337.8
    2-pentanol 526.66
    n-pentane 302.99
    1-propoxy-2-propanol 715.78
    1-methoxy-2-propyl acetate 680.8
    2-(2-methoxypropoxy) propanol 478.23
    mesitylene 277.49
    ε-caprolactone 1386.57
    p-cymene 284.52
    epichlorohydrin 1255.34
    1,1,1-trichloroethane 1724.06
    2-aminoethanol 284.91
    morpholine-4-carbaldehyde 915.99
    sulfolane 1299.48
    2,2,4-trimethylpentane 145.96
    2-methyltetrahydrofuran 1389.7
    n-hexyl acetate 793.74
    isooctane 83.1
    2-(2-butoxyethoxy)ethanol 635.38
    sec-butyl acetate 608.72
    tert-butyl acetate 725.23
    decalin 294.78
    glycerin 263.49
    diglyme 1184.98
    acrylic acid 436.91
    isopropyl myristate 310.15
    n-butyric acid 1036.7
    acetyl acetate 654.37
    di(2-ethylhexyl) phthalate 250.83
    ethyl propionate 668.45
    nitromethane 807.24
    1,2-diethoxyethane 935.4
    benzonitrile 552.05
    trioctyl phosphate 191.15
    1-bromopropane 1044.41
    gamma-valerolactone 1399.77
    n-decanol 197.43
    triethyl phosphate 355.11
    4-methyl-2-pentanol 300.99
    propionitrile 572.94
    vinylene carbonate 710.58
    1,1,2-trichlorotrifluoroethane 1174.38
    DMS 489.27
    cumene 254.81
    2-octanol 220.9
    2-hexanone 610.56
    octyl acetate 358.05
    limonene 509.43
    1,2-dimethoxyethane 984.64
    ethyl orthosilicate 371.69
    tributyl phosphate 279.83
    diacetone alcohol 572.23
    N,N-dimethylaniline 316.52
    acrylonitrile 517.16
    aniline 520.34
    1,3-propanediol 441.02
    bromobenzene 808.24
    dibromomethane 1649.23
    1,1,2,2-tetrachloroethane 2302.66
    2-methyl-cyclohexyl acetate 587.61
    tetrabutyl urea 309.95
    diisobutyl methanol 308.5
    2-phenylethanol 374.67
    styrene 391.31
    dioctyl adipate 445.53
    dimethyl sulfate 270.11
    ethyl butyrate 713.24
    methyl lactate 280.1
    butyl lactate 478.75
    diethyl carbonate 458.81
    propanediol butyl ether 436.55
    triethyl orthoformate 586.03
    p-tert-butyltoluene 267.48
    methyl 4-tert-butylbenzoate 447.21
    morpholine 1462.35
    tert-butylamine 635.78
    n-dodecanol 152.32
    dimethoxymethane 447.58
    ethylene carbonate 713.32
    cyrene 390.86
    2-ethoxyethyl acetate 671.55
    2-ethylhexyl acetate 691.0
    1,2,4-trichlorobenzene 894.91
    4-methylpyridine 870.45
    dibutyl ether 699.5
    2,6-dimethyl-4-heptanol 308.5
    DEF 757.6
    dimethyl isosorbide 769.02
    tetrachloroethylene 1695.56
    eugenol 371.44
    triacetin 748.39
    span 80 535.6
    1,4-butanediol 192.24
    1,1-dichloroethane 1498.71
    2-methyl-1-pentanol 411.75
    methyl formate 254.97
    2-methyl-1-butanol 565.94
    n-decane 118.61
    butyronitrile 611.52
    3,7-dimethyl-1-octanol 345.71
    1-chlorooctane 365.95
    1-chlorotetradecane 130.56
    n-nonane 134.33
    undecane 72.93
    tert-butylcyclohexane 230.31
    cyclooctane 290.17
    cyclopentanol 845.57
    tetrahydropyran 1767.85
    tert-amyl methyl ether 710.25
    2,5,8-trioxanonane 739.41
    1-hexene 725.92
    2-isopropoxyethanol 527.63
    2,2,2-trifluoroethanol 271.1
    methyl butyrate 820.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction