dodecyl beta-D-maltoside

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  • Identifiers

    CAS number
    69227-93-6

    Molecular formula
    C24H46O11

    SMILES
    CCCCCCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 48.71%
    Sweet 37.35%
    Oily 28.65%
    Citrus 24.74%
    Fresh 23.91%
    Waxy 21.5%
    Milky 20.98%
    Alcoholic 20.57%
    Clean 20.0%
    Lactonic 19.96%

     

    Flavor
    Sweet 42.84%
    Fatty 39.75%
    Odorless 36.36%
    Waxy 29.73%
    Sweet-like 27.42%
    Bitter 26.38%
    Mild 25.99%
    Bland 25.49%
    Oily 24.7%
    Cauliflower 22.01%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    6.14 (neutral)

    Molecular weight
    510.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2785°C

    Flash point

    • 234.19 ˚C est.

  • Synonyms

    • 69227-93-6
    • n-DODECYL-beta-D-MALTOSIDE
    • Dodecyl maltoside
    • Lauryl maltoside
    • dodecyl beta-maltoside
    • Dodecyl beta-D-maltoside
    • DI107E57B4
    • n-Dodecyl-b-D-maltoside
    • CHEBI:43769
    • beta-D-Glucopyranoside, dodecyl 4-O-alpha-D-glucopyranosyl-
    • RefChem:135502
    • dodecyl(-beta-D-)maltoside
    • N-Dodecyl b-D-maltoside
    • Dodecyl-beta-D-maltoside
    • n-Dodecyl beta-D-maltoside
    • MFCD00043012
    • N-Dodecyl-|A-D-maltoside
    • (2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-6-(Dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • Dodecyl b-D-maltopyranoside
    • n-Dodecyl |A-D-maltoside
    • dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-dodecoxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • C24H46O11
    • LMT
    • (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-dodecoxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
    • UNII-DI107E57B4
    • (2R,3R,4S,5S,6R)-2-[[(2R,3S,4R,5R,6R)-6-(Dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]oxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • lauryl beta-maltoside
    • lauryl beta-D-maltoside
    • n-Dodecyl |_-D-maltoside
    • Dodecyl |A-D-maltopyranoside
    • n-Dodecyl-I(2)-D-maltoside
    • SCHEMBL411624
    • orb1307988
    • CHEMBL1234047
    • DTXSID30988948
    • LAURYL-.BETA.-D-MALTOSIDE
    • NLEBIOOXCVAHBD-QKMCSOCLSA-N
    • N-DODECYL .BETA.-D-MALTOSIDE
    • AKOS016011222
    • DD06199
    • dodecyl 4-O-hexopyranosylhexopyranoside
    • DS-6568
    • DA-76061
    • SY066327
    • HY-128974
    • n-Dodecyl beta-D-maltoside, >=98% (GC)
    • CS-0102968
    • NS00123785
    • 1-O-N-DODECYL-.BETA.-DMALTOPYRANOSIDE
    • D-8823
    • F14800
    • 227D936
    • n-Dodecyl beta-D-maltoside, BioXtra, >=98% (GC)
    • b-D-Glucopyranoside, dodecyl 4-O-a-D-glucopyranosyl-
    • Q27120527
    • dodecyl alpha-D-glucopyranosyl-9(1->4)-beta-D-glucopyranoside
    • 69227-93-6

  • Applications

    dodecyl beta-D-maltoside (CAS 69227-93-6) (DDM) is primarily used as a nonionic surfactant and mild solubilizer in biology and industry to solubilize, stabilize, and purify membrane proteins and membrane protein complexes; it is routinely used in sample preparation for structural analysis of membrane proteins and in crystallography. In analytical chemistry and biotech development, dodecyl beta-D-maltoside serves as a solvent or solubilizer for hydrophobic compounds and as support in enzyme assays. In cosmetics and personal care, it can function as a mild surfactant in formulations intended for gentle cleansing. In pharmaceutical and formulation work, dodecyl beta-D-maltoside may act as a solubilizer and stabilizer for poorly soluble drugs and as a gentle emulsifying component in certain emulsions, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.38
    methanol 27.54
    isopropanol 2.5
    water 25.32
    ethyl acetate 4.19
    n-propanol 4.88
    acetone 8.57
    n-butanol 3.19
    acetonitrile 2.3
    DMF 49.12
    toluene 1.44
    isobutanol 2.28
    1,4-dioxane 10.58
    methyl acetate 4.29
    THF 15.62
    2-butanone 5.09
    n-pentanol 2.56
    sec-butanol 2.44
    n-hexane 0.11
    ethylene glycol 15.98
    NMP 108.86
    cyclohexane 0.47
    DMSO 185.87
    n-butyl acetate 2.2
    n-octanol 3.14
    chloroform 3.6
    n-propyl acetate 2.37
    acetic acid 65.96
    dichloromethane 4.45
    cyclohexanone 15.41
    propylene glycol 14.31
    isopropyl acetate 3.28
    DMAc 70.2
    2-ethoxyethanol 16.69
    isopentanol 2.12
    n-heptane 0.25
    ethyl formate 5.07
    1,2-dichloroethane 3.87
    n-hexanol 1.97
    2-methoxyethanol 33.39
    isobutyl acetate 1.46
    tetrachloromethane 1.31
    n-pentyl acetate 5.17
    transcutol 49.65
    n-heptanol 3.73
    ethylbenzene 0.76
    MIBK 2.85
    2-propoxyethanol 12.32
    tert-butanol 2.54
    MTBE 1.31
    2-butoxyethanol 15.0
    propionic acid 13.02
    o-xylene 1.76
    formic acid 102.71
    diethyl ether 1.52
    m-xylene 1.32
    p-xylene 0.85
    chlorobenzene 1.28
    dimethyl carbonate 10.66
    n-octane 0.19
    formamide 82.1
    cyclopentanone 20.88
    2-pentanone 4.6
    anisole 1.93
    cyclopentyl methyl ether 7.44
    gamma-butyrolactone 31.5
    1-methoxy-2-propanol 19.7
    pyridine 6.78
    3-pentanone 4.42
    furfural 30.4
    n-dodecane 0.14
    diethylene glycol 20.76
    diisopropyl ether 0.58
    tert-amyl alcohol 2.84
    acetylacetone 14.13
    n-hexadecane 0.16
    acetophenone 5.38
    methyl propionate 7.58
    isopentyl acetate 2.33
    trichloroethylene 8.31
    n-nonanol 3.15
    cyclohexanol 5.31
    benzyl alcohol 4.7
    2-ethylhexanol 1.29
    isooctanol 2.66
    dipropyl ether 1.59
    1,2-dichlorobenzene 1.79
    ethyl lactate 7.01
    propylene carbonate 14.94
    n-methylformamide 27.43
    2-pentanol 1.71
    n-pentane 0.15
    1-propoxy-2-propanol 8.29
    1-methoxy-2-propyl acetate 8.41
    2-(2-methoxypropoxy) propanol 13.56
    mesitylene 0.87
    ε-caprolactone 19.05
    p-cymene 0.91
    epichlorohydrin 16.48
    1,1,1-trichloroethane 2.14
    2-aminoethanol 18.48
    morpholine-4-carbaldehyde 63.71
    sulfolane 119.91
    2,2,4-trimethylpentane 0.13
    2-methyltetrahydrofuran 7.16
    n-hexyl acetate 5.62
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 19.57
    sec-butyl acetate 1.78
    tert-butyl acetate 4.19
    decalin 0.24
    glycerin 46.14
    diglyme 33.35
    acrylic acid 23.1
    isopropyl myristate 1.66
    n-butyric acid 12.07
    acetyl acetate 6.9
    di(2-ethylhexyl) phthalate 3.74
    ethyl propionate 2.56
    nitromethane 56.54
    1,2-diethoxyethane 5.31
    benzonitrile 2.62
    trioctyl phosphate 3.08
    1-bromopropane 1.09
    gamma-valerolactone 49.91
    n-decanol 2.03
    triethyl phosphate 3.33
    4-methyl-2-pentanol 1.04
    propionitrile 1.47
    vinylene carbonate 14.13
    1,1,2-trichlorotrifluoroethane 49.12
    DMS 7.22
    cumene 0.63
    2-octanol 1.99
    2-hexanone 2.54
    octyl acetate 3.23
    limonene 1.43
    1,2-dimethoxyethane 10.83
    ethyl orthosilicate 2.9
    tributyl phosphate 2.86
    diacetone alcohol 12.76
    N,N-dimethylaniline 2.51
    acrylonitrile 3.35
    aniline 3.48
    1,3-propanediol 16.24
    bromobenzene 1.08
    dibromomethane 2.19
    1,1,2,2-tetrachloroethane 8.11
    2-methyl-cyclohexyl acetate 3.29
    tetrabutyl urea 4.91
    diisobutyl methanol 0.87
    2-phenylethanol 3.46
    styrene 0.76
    dioctyl adipate 4.4
    dimethyl sulfate 38.88
    ethyl butyrate 2.4
    methyl lactate 19.68
    butyl lactate 9.49
    diethyl carbonate 1.93
    propanediol butyl ether 18.22
    triethyl orthoformate 3.15
    p-tert-butyltoluene 0.97
    methyl 4-tert-butylbenzoate 12.19
    morpholine 16.02
    tert-butylamine 0.89
    n-dodecanol 1.33
    dimethoxymethane 18.81
    ethylene carbonate 10.35
    cyrene 27.0
    2-ethoxyethyl acetate 10.41
    2-ethylhexyl acetate 1.78
    1,2,4-trichlorobenzene 3.11
    4-methylpyridine 4.35
    dibutyl ether 1.48
    2,6-dimethyl-4-heptanol 0.87
    DEF 12.87
    dimethyl isosorbide 22.11
    tetrachloroethylene 7.1
    eugenol 10.35
    triacetin 15.18
    span 80 14.13
    1,4-butanediol 7.89
    1,1-dichloroethane 1.68
    2-methyl-1-pentanol 2.03
    methyl formate 20.82
    2-methyl-1-butanol 2.48
    n-decane 0.26
    butyronitrile 1.23
    3,7-dimethyl-1-octanol 1.91
    1-chlorooctane 1.06
    1-chlorotetradecane 0.42
    n-nonane 0.23
    undecane 0.18
    tert-butylcyclohexane 0.14
    cyclooctane 0.28
    cyclopentanol 7.3
    tetrahydropyran 5.16
    tert-amyl methyl ether 1.96
    2,5,8-trioxanonane 24.92
    1-hexene 0.31
    2-isopropoxyethanol 8.59
    2,2,2-trifluoroethanol 41.05
    methyl butyrate 3.64

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction