Dodecyl beta-D-glucopyranoside

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  • Identifiers

    CAS number
    59122-55-3

    Molecular formula
    C18H36O6

    SMILES
    CCCCCCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Oily 39.09%
    Sweet 37.03%
    Waxy 36.89%
    Citrus 36.6%
    Odorless 34.36%
    Fresh 33.26%
    Fatty 30.95%
    Fruity 28.0%
    Clean 23.62%
    Lactonic 23.47%

     

    Flavor
    Fatty 44.78%
    Waxy 41.72%
    Oily 33.0%
    Sweet 32.24%
    Mild 32.19%
    Odorless 27.95%
    Coconut 25.79%
    Bland 25.24%
    Creamy 24.65%
    Sweet-like 23.78%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    6.28 (neutral)

    Molecular weight
    348.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    757°C

    Flash point

    • 204.14 ˚C est.

  • Synonyms

    • 59122-55-3
    • Dodecyl glucoside
    • Dodecyl beta-D-glucopyranoside
    • Dodecyl glucopyranoside
    • DTXSID40891954
    • RefChem:135497
    • DTXCID301035930
    • 261-614-4
    • n-DODECYL-beta-D-GLUCOPYRANOSIDE
    • Dodecyl b-D-glucopyranoside
    • dodecyl |A-d-glucopyranoside
    • MFCD00063298
    • Dodecyl-beta-D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-dodecoxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • C18H36O6
    • (2R,3R,4S,5S,6R)-2-(dodecyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol
    • Dodecyl-BATE-D-glucopyranoside
    • Dodecylb-D-glucopyranoside
    • Dodecyl-|A-D-glucopyranoside
    • .beta.-D-Glucopyranoside, dodecyl
    • XKJ
    • EINECS 261-614-4
    • dodecyl-beta-d-glucoside
    • SCHEMBL60522
    • n-Dodecyl-?-D-Glucopyranoside
    • orb2276886
    • CHEMBL4068837
    • 1-dodecyl beta-D-glucopyranoside
    • n-Dodecyl-I(2)-D-glucopyranoside
    • 85618-22-0
    • n-Dodecyl- beta -D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-dodecoxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
    • AKOS015919432
    • DD06359
    • HY-W142692
    • DODECYL .BETA.-D-GLUCOPYRANOSIDE
    • AS-60935
    • CS-0204726
    • D5938
    • NS00088690
    • C16041
    • n-Dodecyl beta-D-glucopyranoside, >=98% (GC)
    • 618D220
    • Q2614811
    • Dodecyl fA-D-Glucopyranoside [for Biochemical Research]
    • 59122-55-3

  • Applications

    Dodecyl beta-D-glucopyranoside (CAS 59122-55-3) is a nonionic surfactant used widely for its mildness and environmental compatibility; in cosmetics and personal care it acts as a mild cleansing surfactant, an emulsifier, and a foam stabilizer in products such as shampoos, facial cleansers, and moisturizers; in household cleaning products it functions as a surfactant and emulsifier, improving cleaning performance and oil dispersal; in industrial cleaning formulations it serves as a co-surfactant and wetting agent to enhance cleaning efficiency; in coatings and inks it serves as a wetting agent and dispersant to improve substrate wetting and pigment dispersion; in the polymers/plastics sector it can act as an emulsifier or dispersant in polymer emulsions and resin systems to improve stability and particle dispersion.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 69.79
    methanol 208.69
    isopropanol 33.79
    water 7.1
    ethyl acetate 61.25
    n-propanol 51.53
    acetone 90.01
    n-butanol 42.78
    acetonitrile 24.84
    DMF 187.9
    toluene 12.74
    isobutanol 35.8
    1,4-dioxane 98.09
    methyl acetate 45.68
    THF 183.98
    2-butanone 50.73
    n-pentanol 31.26
    sec-butanol 31.49
    n-hexane 1.2
    ethylene glycol 48.55
    NMP 319.64
    cyclohexane 8.94
    DMSO 1017.5
    n-butyl acetate 44.4
    n-octanol 26.95
    chloroform 65.35
    n-propyl acetate 46.56
    acetic acid 292.52
    dichloromethane 77.83
    cyclohexanone 185.74
    propylene glycol 56.99
    isopropyl acetate 56.22
    DMAc 237.29
    2-ethoxyethanol 132.47
    isopentanol 44.31
    n-heptane 2.5
    ethyl formate 58.35
    1,2-dichloroethane 75.38
    n-hexanol 27.61
    2-methoxyethanol 221.85
    isobutyl acetate 29.67
    tetrachloromethane 18.66
    n-pentyl acetate 63.02
    transcutol 373.71
    n-heptanol 37.15
    ethylbenzene 9.36
    MIBK 47.95
    2-propoxyethanol 97.34
    tert-butanol 60.8
    MTBE 26.43
    2-butoxyethanol 115.07
    propionic acid 109.35
    o-xylene 17.58
    formic acid 244.61
    diethyl ether 17.12
    m-xylene 14.7
    p-xylene 13.25
    chlorobenzene 24.82
    dimethyl carbonate 48.52
    n-octane 1.85
    formamide 303.99
    cyclopentanone 232.0
    2-pentanone 53.45
    anisole 23.72
    cyclopentyl methyl ether 80.58
    gamma-butyrolactone 300.28
    1-methoxy-2-propanol 137.05
    pyridine 66.71
    3-pentanone 43.48
    furfural 218.65
    n-dodecane 1.4
    diethylene glycol 122.78
    diisopropyl ether 10.69
    tert-amyl alcohol 49.71
    acetylacetone 139.33
    n-hexadecane 1.59
    acetophenone 55.79
    methyl propionate 64.26
    isopentyl acetate 47.95
    trichloroethylene 136.35
    n-nonanol 25.59
    cyclohexanol 81.53
    benzyl alcohol 45.75
    2-ethylhexanol 20.93
    isooctanol 33.55
    dipropyl ether 16.89
    1,2-dichlorobenzene 35.19
    ethyl lactate 56.56
    propylene carbonate 148.44
    n-methylformamide 139.11
    2-pentanol 26.27
    n-pentane 1.54
    1-propoxy-2-propanol 71.87
    1-methoxy-2-propyl acetate 81.68
    2-(2-methoxypropoxy) propanol 80.01
    mesitylene 13.03
    ε-caprolactone 192.79
    p-cymene 12.2
    epichlorohydrin 196.95
    1,1,1-trichloroethane 51.14
    2-aminoethanol 85.97
    morpholine-4-carbaldehyde 243.4
    sulfolane 666.19
    2,2,4-trimethylpentane 2.41
    2-methyltetrahydrofuran 91.3
    n-hexyl acetate 59.72
    isooctane 1.47
    2-(2-butoxyethoxy)ethanol 119.54
    sec-butyl acetate 34.1
    tert-butyl acetate 75.3
    decalin 4.2
    glycerin 141.07
    diglyme 234.42
    acrylic acid 119.52
    isopropyl myristate 19.12
    n-butyric acid 159.81
    acetyl acetate 74.38
    di(2-ethylhexyl) phthalate 30.58
    ethyl propionate 40.21
    nitromethane 328.58
    1,2-diethoxyethane 56.44
    benzonitrile 41.26
    trioctyl phosphate 27.54
    1-bromopropane 18.43
    gamma-valerolactone 350.36
    n-decanol 17.09
    triethyl phosphate 34.81
    4-methyl-2-pentanol 21.38
    propionitrile 19.74
    vinylene carbonate 123.04
    1,1,2-trichlorotrifluoroethane 292.42
    DMS 59.46
    cumene 9.33
    2-octanol 22.51
    2-hexanone 32.96
    octyl acetate 28.7
    limonene 18.9
    1,2-dimethoxyethane 118.28
    ethyl orthosilicate 31.94
    tributyl phosphate 30.5
    diacetone alcohol 127.89
    N,N-dimethylaniline 24.99
    acrylonitrile 35.78
    aniline 34.27
    1,3-propanediol 134.89
    bromobenzene 22.29
    dibromomethane 42.76
    1,1,2,2-tetrachloroethane 134.56
    2-methyl-cyclohexyl acetate 44.94
    tetrabutyl urea 39.51
    diisobutyl methanol 16.28
    2-phenylethanol 40.11
    styrene 9.92
    dioctyl adipate 43.94
    dimethyl sulfate 142.91
    ethyl butyrate 37.94
    methyl lactate 87.91
    butyl lactate 86.31
    diethyl carbonate 29.07
    propanediol butyl ether 102.92
    triethyl orthoformate 37.56
    p-tert-butyltoluene 12.67
    methyl 4-tert-butylbenzoate 86.11
    morpholine 134.58
    tert-butylamine 23.49
    n-dodecanol 12.03
    dimethoxymethane 98.17
    ethylene carbonate 114.06
    cyrene 123.42
    2-ethoxyethyl acetate 92.51
    2-ethylhexyl acetate 34.15
    1,2,4-trichlorobenzene 50.56
    4-methylpyridine 45.26
    dibutyl ether 17.49
    2,6-dimethyl-4-heptanol 16.28
    DEF 105.25
    dimethyl isosorbide 142.02
    tetrachloroethylene 108.77
    eugenol 75.0
    triacetin 106.59
    span 80 77.0
    1,4-butanediol 51.34
    1,1-dichloroethane 35.82
    2-methyl-1-pentanol 33.13
    methyl formate 102.14
    2-methyl-1-butanol 40.28
    n-decane 2.54
    butyronitrile 21.08
    3,7-dimethyl-1-octanol 25.62
    1-chlorooctane 12.45
    1-chlorotetradecane 4.55
    n-nonane 2.23
    undecane 1.77
    tert-butylcyclohexane 2.7
    cyclooctane 3.58
    cyclopentanol 89.45
    tetrahydropyran 67.23
    tert-amyl methyl ether 28.04
    2,5,8-trioxanonane 146.49
    1-hexene 3.9
    2-isopropoxyethanol 82.77
    2,2,2-trifluoroethanol 181.77
    methyl butyrate 59.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction