Dodecanedioic Acid

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  • Identifiers

    CAS number
    693-23-2

    Molecular formula
    C12H22O4

    SMILES
    C(CCCCCC(=O)O)CCCCC(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fatty 57.71%
    Waxy 44.22%
    Odorless 39.0%
    Sour 35.85%
    Cheesy 30.63%
    Dairy 27.92%
    Milky 27.4%
    Creamy 27.27%
    Savory 24.62%
    Oily 24.55%

     

    Flavor
    Fatty 62.72%
    Waxy 56.23%
    Cheese 47.38%
    Sour 39.45%
    Odorless 38.1%
    Oily 36.97%
    Rancid 35.36%
    Sweat 32.84%
    Mild 32.13%
    Creamy 31.51%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    6.14 (neutral)

    Molecular weight
    230.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    363°C

    Melting point expt.

    • 130-132 °C
    • 127 - 129 °C

    Flash point

    • 203.54 ˚C est.

    Solubility expt.

    • SOL IN HOT TOLUENE, ALC, HOT ACETIC ACID; SLIGHTLY SOL IN HOT WATER
    • 0.04 mg/mL

  • Synonyms

    • DODECANEDIOIC ACID
    • 693-23-2
    • 1,12-Dodecanedioic acid
    • 1,10-Decanedicarboxylic acid
    • Decamethylenedicarboxylic acid
    • 1,10-Dicarboxydecane
    • DTXSID3027297
    • 978YU42Q6I
    • NSC-400242
    • CHEBI:4676
    • DTXCID607297
    • dodecandioic acid
    • RefChem:7336
    • 211-746-3
    • MFCD00002735
    • n-Dodecanedioic acid
    • Decane-1,10-dicarboxylic acid
    • NSC400242
    • Dodecanedioicacid
    • 53037-60-8
    • CAS-693-23-2
    • HSDB 5745
    • EINECS 211-746-3
    • NSC 400242
    • UNII-978YU42Q6I
    • n-Dodecanedioate
    • dodecane dioic acid
    • Corfree M 2
    • 1,12-Dodecanedioate
    • n-Dodecane-a,w-dioate
    • 1,10-dicarboxy decane
    • SL-AH
    • Decamethylenedicarboxylate
    • 1,10-Decanedicarboxylate
    • Dodecanedioic acid, 99%
    • n-Dodecane-a,w-dioic acid
    • Dodecanedioic acid (NIST)
    • Dodecanedioic acid, Refined
    • EC 211-746-3
    • SCHEMBL29467
    • 1, 10-Decanedicarboxylic acid
    • orb1704833
    • SCHEMBL8671826
    • CHEMBL3182356
    • DODECANEDIOIC ACID [HSDB]
    • Tox21_201954
    • Tox21_303308
    • BBL018825
    • LMFA01170009
    • s6267
    • SBB060281
    • STL195386
    • AKOS015892807
    • CS-W012957
    • EBC-152080
    • HY-W012241
    • SB74075
    • NCGC00163995-01
    • NCGC00163995-02
    • NCGC00257191-01
    • NCGC00259503-01
    • AC-10611
    • DS-18055
    • DB-311306
    • D0013
    • NS00010129
    • ST51046498
    • C02678
    • F16287
    • N-DODECANE-.ALPHA.,.OMEGA.-DIOIC ACID
    • EN300-1081985
    • F229150
    • Q5287812
    • Z2044738279
    • 693-23-2

  • Applications

    Dodecanedioic Acid (CAS 693-23-2) is used primarily as a diacid monomer in the production of aliphatic polyesters and polyamides, enabling flexible, hydrolytically stable polymers for applications such as packaging, coatings and adhesives; it is also converted to diester derivatives that function as plasticizers or lubricants in polymer formulations, and serves as a building block for high‑performance resins and crosslinkable systems used in electronics packaging and protective coatings; in addition, it can be explored as a renewable or bio‑based feedstock component in sustainable polymer syntheses, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 46.65
    methanol 49.87
    isopropanol 29.58
    water 0.09
    ethyl acetate 6.34
    n-propanol 23.89
    acetone 16.1
    n-butanol 21.48
    acetonitrile 3.8
    DMF 119.38
    toluene 4.2
    isobutanol 17.31
    1,4-dioxane 24.57
    methyl acetate 7.65
    THF 135.52
    2-butanone 13.55
    n-pentanol 21.78
    sec-butanol 18.73
    n-hexane 3.19
    ethylene glycol 9.82
    NMP 176.79
    cyclohexane 1.92
    DMSO 319.45
    n-butyl acetate 20.62
    n-octanol 14.97
    chloroform 19.16
    n-propyl acetate 16.35
    acetic acid 26.39
    dichloromethane 17.41
    cyclohexanone 52.66
    propylene glycol 23.51
    isopropyl acetate 11.59
    DMAc 142.66
    2-ethoxyethanol 53.62
    isopentanol 23.43
    n-heptane 1.6
    ethyl formate 9.47
    1,2-dichloroethane 18.23
    n-hexanol 19.57
    2-methoxyethanol 74.66
    isobutyl acetate 14.0
    tetrachloromethane 3.57
    n-pentyl acetate 21.02
    transcutol 172.45
    n-heptanol 14.34
    ethylbenzene 7.32
    MIBK 22.59
    2-propoxyethanol 54.53
    tert-butanol 45.72
    MTBE 17.41
    2-butoxyethanol 40.74
    propionic acid 20.48
    o-xylene 8.51
    formic acid 17.63
    diethyl ether 8.55
    m-xylene 7.43
    p-xylene 9.31
    chlorobenzene 6.62
    dimethyl carbonate 6.62
    n-octane 1.04
    formamide 26.71
    cyclopentanone 84.98
    2-pentanone 16.74
    anisole 16.63
    cyclopentyl methyl ether 39.8
    gamma-butyrolactone 85.9
    1-methoxy-2-propanol 70.34
    pyridine 19.02
    3-pentanone 10.43
    furfural 67.01
    n-dodecane 0.85
    diethylene glycol 44.31
    diisopropyl ether 5.78
    tert-amyl alcohol 33.45
    acetylacetone 29.2
    n-hexadecane 0.97
    acetophenone 26.35
    methyl propionate 9.5
    isopentyl acetate 26.71
    trichloroethylene 31.03
    n-nonanol 15.08
    cyclohexanol 22.82
    benzyl alcohol 18.92
    2-ethylhexanol 14.75
    isooctanol 13.7
    dipropyl ether 13.45
    1,2-dichlorobenzene 10.87
    ethyl lactate 19.06
    propylene carbonate 39.71
    n-methylformamide 28.27
    2-pentanol 14.84
    n-pentane 1.32
    1-propoxy-2-propanol 45.25
    1-methoxy-2-propyl acetate 32.24
    2-(2-methoxypropoxy) propanol 52.46
    mesitylene 6.98
    ε-caprolactone 50.83
    p-cymene 7.1
    epichlorohydrin 59.38
    1,1,1-trichloroethane 11.7
    2-aminoethanol 27.92
    morpholine-4-carbaldehyde 105.22
    sulfolane 229.68
    2,2,4-trimethylpentane 1.9
    2-methyltetrahydrofuran 48.94
    n-hexyl acetate 28.7
    isooctane 1.44
    2-(2-butoxyethoxy)ethanol 67.12
    sec-butyl acetate 13.77
    tert-butyl acetate 27.47
    decalin 3.27
    glycerin 43.22
    diglyme 106.19
    acrylic acid 18.11
    isopropyl myristate 12.91
    n-butyric acid 28.94
    acetyl acetate 8.01
    di(2-ethylhexyl) phthalate 17.22
    ethyl propionate 12.57
    nitromethane 30.93
    1,2-diethoxyethane 29.76
    benzonitrile 12.42
    trioctyl phosphate 12.63
    1-bromopropane 9.45
    gamma-valerolactone 112.24
    n-decanol 10.48
    triethyl phosphate 16.31
    4-methyl-2-pentanol 14.4
    propionitrile 5.36
    vinylene carbonate 25.8
    1,1,2-trichlorotrifluoroethane 67.51
    DMS 18.58
    cumene 8.11
    2-octanol 10.71
    2-hexanone 22.31
    octyl acetate 15.95
    limonene 10.55
    1,2-dimethoxyethane 74.19
    ethyl orthosilicate 16.73
    tributyl phosphate 16.5
    diacetone alcohol 55.89
    N,N-dimethylaniline 21.38
    acrylonitrile 7.72
    aniline 9.59
    1,3-propanediol 38.4
    bromobenzene 6.41
    dibromomethane 13.33
    1,1,2,2-tetrachloroethane 37.0
    2-methyl-cyclohexyl acetate 26.88
    tetrabutyl urea 27.21
    diisobutyl methanol 11.52
    2-phenylethanol 19.12
    styrene 6.67
    dioctyl adipate 24.55
    dimethyl sulfate 29.31
    ethyl butyrate 17.97
    methyl lactate 22.24
    butyl lactate 28.34
    diethyl carbonate 11.69
    propanediol butyl ether 48.89
    triethyl orthoformate 19.19
    p-tert-butyltoluene 7.4
    methyl 4-tert-butylbenzoate 39.24
    morpholine 50.31
    tert-butylamine 24.44
    n-dodecanol 7.41
    dimethoxymethane 38.91
    ethylene carbonate 19.45
    cyrene 57.79
    2-ethoxyethyl acetate 27.16
    2-ethylhexyl acetate 19.95
    1,2,4-trichlorobenzene 14.31
    4-methylpyridine 19.11
    dibutyl ether 15.42
    2,6-dimethyl-4-heptanol 11.52
    DEF 32.52
    dimethyl isosorbide 94.68
    tetrachloroethylene 22.59
    eugenol 39.1
    triacetin 36.77
    span 80 47.77
    1,4-butanediol 16.07
    1,1-dichloroethane 9.43
    2-methyl-1-pentanol 22.28
    methyl formate 14.91
    2-methyl-1-butanol 18.79
    n-decane 1.6
    butyronitrile 8.65
    3,7-dimethyl-1-octanol 15.7
    1-chlorooctane 7.34
    1-chlorotetradecane 2.99
    n-nonane 1.42
    undecane 1.12
    tert-butylcyclohexane 3.19
    cyclooctane 1.01
    cyclopentanol 35.09
    tetrahydropyran 27.07
    tert-amyl methyl ether 19.02
    2,5,8-trioxanonane 86.1
    1-hexene 9.22
    2-isopropoxyethanol 38.57
    2,2,2-trifluoroethanol 11.81
    methyl butyrate 21.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction