Dl-Phenylalanine

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  • Identifiers

    CAS number
    150-30-1

    Molecular formula
    C9H11NO2

    SMILES
    C1=CC=C(C=C1)CC(C(=O)O)N

  • Odor profile

    Fragrance
    Sweet 39.54%
    Odorless 38.78%
    Honey 28.32%
    Bitter 28.3%
    Cocoa 28.26%
    Balsamic 25.64%
    Chocolate 24.57%
    Spicy 24.12%
    Savory 21.82%
    Floral 21.55%

     

    Flavor
    Odorless 56.66%
    Mild 43.35%
    Bitter 23.73%
    Faint 23.06%
    Nitrile 20.86%
    Yeast 20.63%
    Honeysuckle 20.56%
    Urine 20.32%
    Sweet-like 19.95%
    Bland 19.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.5

    pKa est.
    5.22 (weak acid)

    Molecular weight
    165.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    314°C

    Flash point

    • 169.27 ˚C est.

    Solubility expt.

    • Soluble in water and dilute mineral acid and alkali hydroxide solutions
    • Slightly soluble (in ethanol)

  • Synonyms

    • DL-PHENYLALANINE
    • 150-30-1
    • 2-amino-3-phenylpropanoic acid
    • DL-3-Phenylalanine
    • H-DL-Phe-OH
    • DLPA
    • Phenylalanine DL-form
    • Phenylalanine, dl-
    • DL-2-Amino-3-phenylpropanoic acid
    • Alanine, phenyl-, dl-
    • FEMA No. 3726
    • NSC 9959
    • MFCD00064225
    • DL-.beta.-Phenylalanine
    • d,l-phenylalanine
    • EINECS 205-756-7
    • phenylalanin
    • alpha-Amino-beta-phenylpropionic acid
    • 2-Amino-3-phenylpropionic acid, dl-
    • CCRIS 8601
    • DTXSID9023463
    • CHEBI:28044
    • AI3-18436
    • PHENYLALANINE DL
    • NSC9959
    • 8P946UF12S
    • NSC-9959
    • .beta.-Phenylalanine, dl-
    • DL-PHENYLALANINE [FCC]
    • DTXCID103463
    • DL-PHENYLALANINE [FHFI]
    • 3617-44-5
    • DL-PHENYLALANINE [WHO-DD]
    • DL-.beta.-Phenyl-.alpha.-alanine
    • PHENYLALANINE DL-FORM [MI]
    • DL-PHENYLALANINE-CARBOXY-13C
    • DL-PHENYL(ALANINE-3-13C)
    • (2S)-2-amino-3-phenyl-propanoic acid
    • (+/-)-2-Amino-3-phenylpropionic acid
    • DL-2-AMINO-3-PHENYLPROPIONIC ACID
    • DL-.alpha.-Amino-.beta.-phenylpropionic acid
    • (+/-)-.BETA.-PHENYL-.ALPHA.-ALANINE
    • 67675-33-6
    • 180268-82-0
    • Alanine, phenyl-
    • 2-Amino-3-phenylpropionic acid
    • L-Phenylalanine-d8
    • .beta.-Phenylalanine
    • PHENYLALANINE,CLINICAL DETECTION,GENERAL BACTERIA TINY BIOCHEMICAL IDENTIFICATION TUBE
    • Phenyl-.alpha.-alanine
    • D-.beta.-Phenylalanine
    • L-.beta.-Phenylalanine
    • .beta.-Phenyl-L-alanine
    • DL-alpha-Amino-beta-phenylpropionic acid
    • (-)-.beta.-Phenylalanine
    • alpha-Aminohydrocinnamic acid, dl-
    • 30394-07-1
    • .alpha.-Aminohydrocinnamic acid
    • .beta.-Phenyl-.alpha.-alanine
    • L-PHENYLALANINE (2-13C)
    • Hydrocinnamic acid, .alpha.-amino-
    • UNII-8P946UF12S
    • .beta.-Phenyl-.alpha.-alanine, l-
    • DL3Phenylalanine
    • Butane,4-dichloro-1,4-diphenyl
    • Phenylalanine, dl
    • DL-phenyl alanine
    • d,1-phenylalanine
    • (RS)-phenylalanine
    • .alpha.-Amino-.beta.-phenylpropionic acid
    • Phenylalanine DLform
    • Alanine, phenyl, DL
    • (+/-)-phenylalanine
    • PHENYLALANINE,DL-
    • (.+-.)-Phenylalanine
    • Phe142
    • D,L-PHE
    • (DL)-PHENYLALANINE
    • (.+/-.)-Phenylalanine
    • WLN: QVYZ1R -L
    • SCHEMBL8118
    • NCIOpen2_000782
    • DL2Amino3phenylpropanoic acid
    • C6H5CH2CH(NH2)COOH
    • CHEMBL25080
    • 2-azaniumyl-3-phenylpropanoate
    • Alanine, phenyl, DL (8CI)
    • 2-amino 3-phenylpropionic acid
    • 2Amino3phenylpropionic acid, dl
    • alphaAminohydrocinnamic acid, dl
    • DL-Phenylalanine, 99%, FCC
    • (+/)2Amino3phenylpropionic acid
    • 2-Amino-3-phenyl-propionic acid
    • HMS1668C09
    • DLalphaAminobetaphenylpropionic acid
    • L-Phenylalanine, non animal origin
    • BCP16807
    • FHA26882
    • GCA25390
    • HY-B1732
    • MPA04955
    • NSC25005
    • NSC79477
    • PAA24624
    • WIA34631
    • Tox21_110011
    • BDBM50022800
    • NSC620354
    • STL194273
    • AKOS000118905
    • AKOS016842339
    • AB00345
    • AB02573
    • AB02575
    • CS-W018529
    • FP67580
    • NSC-620354
    • DL-Phenylalanine, ReagentPlus(R), 99%
    • NCGC00013103-01
    • NCGC00186640-01
    • (+/-)-BETA-PHENYL-ALPHA-ALANINE
    • AC-24032
    • AS-12096
    • CAS-150-30-1
    • NCI60_042233
    • SY001531
    • SY005120
    • DB-014764

  • Applications

    Dl-Phenylalanine (CAS 150-30-1) is a racemic amino acid used as a chemical building block in several industries: as an intermediate in pharmaceutical synthesis and for the preparation of related specialty compounds; as a dietary supplement ingredient providing phenylalanine in nutraceutical formulations; in cosmetics/personal care, it may be used as an amino acid additive to support conditioning and formulation balance; as a precursor for fragrance and aroma chemistry, enabling synthesis of aroma compounds derived from phenylalanine; and as a general industrial starting material for enantioselective syntheses and downstream production of L-phenylalanine via resolution.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.42
    methanol 2.89
    isopropanol 0.14
    water 19.03
    ethyl acetate 0.15
    n-propanol 0.11
    acetone 0.44
    n-butanol 0.07
    acetonitrile 0.08
    DMF 2.42
    toluene 0.4
    isobutanol 0.19
    1,4-dioxane 0.14
    methyl acetate 0.07
    THF 1.23
    2-butanone 0.17
    n-pentanol 0.2
    sec-butanol 0.12
    n-hexane 0.04
    ethylene glycol 7.9
    NMP 43.4
    cyclohexane 0.04
    DMSO 15.27
    n-butyl acetate 1.32
    n-octanol 0.32
    chloroform 0.1
    n-propyl acetate 0.45
    acetic acid 11.52
    dichloromethane 0.17
    cyclohexanone 1.64
    propylene glycol 2.67
    isopropyl acetate 0.56
    DMAc 14.09
    2-ethoxyethanol 4.65
    isopentanol 0.41
    n-heptane 0.16
    ethyl formate 0.45
    1,2-dichloroethane 0.18
    n-hexanol 1.15
    2-methoxyethanol 5.2
    isobutyl acetate 0.48
    tetrachloromethane 0.18
    n-pentyl acetate 0.68
    transcutol 21.01
    n-heptanol 1.01
    ethylbenzene 0.54
    MIBK 1.11
    2-propoxyethanol 8.86
    tert-butanol 1.08
    MTBE 0.24
    2-butoxyethanol 5.06
    propionic acid 1.54
    o-xylene 1.35
    formic acid 61.36
    diethyl ether 0.04
    m-xylene 1.32
    p-xylene 0.72
    chlorobenzene 0.29
    dimethyl carbonate 1.23
    n-octane 0.05
    formamide 33.39
    cyclopentanone 3.07
    2-pentanone 0.26
    anisole 1.2
    cyclopentyl methyl ether 0.99
    gamma-butyrolactone 6.61
    1-methoxy-2-propanol 3.6
    pyridine 0.55
    3-pentanone 0.23
    furfural 14.98
    n-dodecane 0.04
    diethylene glycol 25.36
    diisopropyl ether 0.22
    tert-amyl alcohol 1.07
    acetylacetone 3.06
    n-hexadecane 0.04
    acetophenone 3.67
    methyl propionate 0.3
    isopentyl acetate 2.42
    trichloroethylene 0.56
    n-nonanol 0.4
    cyclohexanol 0.44
    benzyl alcohol 2.27
    2-ethylhexanol 1.5
    isooctanol 1.28
    dipropyl ether 0.57
    1,2-dichlorobenzene 0.82
    ethyl lactate 3.42
    propylene carbonate 5.83
    n-methylformamide 1.76
    2-pentanol 0.12
    n-pentane 0.02
    1-propoxy-2-propanol 5.86
    1-methoxy-2-propyl acetate 5.85
    2-(2-methoxypropoxy) propanol 10.74
    mesitylene 1.29
    ε-caprolactone 2.53
    p-cymene 1.38
    epichlorohydrin 1.6
    1,1,1-trichloroethane 0.18
    2-aminoethanol 4.85
    morpholine-4-carbaldehyde 17.54
    sulfolane 39.81
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 0.59
    n-hexyl acetate 0.83
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 10.34
    sec-butyl acetate 0.6
    tert-butyl acetate 2.34
    decalin 0.17
    glycerin 21.95
    diglyme 15.51
    acrylic acid 4.74
    isopropyl myristate 0.6
    n-butyric acid 1.54
    acetyl acetate 1.06
    di(2-ethylhexyl) phthalate 2.93
    ethyl propionate 0.6
    nitromethane 4.88
    1,2-diethoxyethane 0.93
    benzonitrile 0.86
    trioctyl phosphate 1.48
    1-bromopropane 0.04
    gamma-valerolactone 8.56
    n-decanol 0.37
    triethyl phosphate 2.84
    4-methyl-2-pentanol 0.62
    propionitrile 0.06
    vinylene carbonate 3.44
    1,1,2-trichlorotrifluoroethane 13.74
    DMS 2.11
    cumene 0.9
    2-octanol 0.39
    2-hexanone 0.46
    octyl acetate 0.79
    limonene 1.42
    1,2-dimethoxyethane 2.33
    ethyl orthosilicate 2.51
    tributyl phosphate 1.48
    diacetone alcohol 9.67
    N,N-dimethylaniline 2.77
    acrylonitrile 0.24
    aniline 0.72
    1,3-propanediol 2.38
    bromobenzene 0.26
    dibromomethane 0.1
    1,1,2,2-tetrachloroethane 0.59
    2-methyl-cyclohexyl acetate 3.4
    tetrabutyl urea 2.73
    diisobutyl methanol 1.56
    2-phenylethanol 3.78
    styrene 0.34
    dioctyl adipate 1.53
    dimethyl sulfate 7.86
    ethyl butyrate 1.59
    methyl lactate 5.98
    butyl lactate 3.14
    diethyl carbonate 1.49
    propanediol butyl ether 5.64
    triethyl orthoformate 2.02
    p-tert-butyltoluene 1.32
    methyl 4-tert-butylbenzoate 7.88
    morpholine 0.23
    tert-butylamine 0.42
    n-dodecanol 0.32
    dimethoxymethane 1.36
    ethylene carbonate 2.1
    cyrene 20.6
    2-ethoxyethyl acetate 1.8
    2-ethylhexyl acetate 1.61
    1,2,4-trichlorobenzene 1.24
    4-methylpyridine 0.53
    dibutyl ether 0.18
    2,6-dimethyl-4-heptanol 1.56
    DEF 1.08
    dimethyl isosorbide 23.43
    tetrachloroethylene 1.02
    eugenol 9.48
    triacetin 3.71
    span 80 7.95
    1,4-butanediol 1.98
    1,1-dichloroethane 0.05
    2-methyl-1-pentanol 0.73
    methyl formate 1.53
    2-methyl-1-butanol 0.29
    n-decane 0.04
    butyronitrile 0.07
    3,7-dimethyl-1-octanol 0.76
    1-chlorooctane 0.11
    1-chlorotetradecane 0.09
    n-nonane 0.04
    undecane 0.04
    tert-butylcyclohexane 0.16
    cyclooctane 0.06
    cyclopentanol 0.62
    tetrahydropyran 0.07
    tert-amyl methyl ether 0.43
    2,5,8-trioxanonane 18.14
    1-hexene 0.07
    2-isopropoxyethanol 3.71
    2,2,2-trifluoroethanol 8.29
    methyl butyrate 0.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction