Dixanthogen

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  • Identifiers

    CAS number
    502-55-6

    Molecular formula
    C6H10O2S4

    SMILES
    CCOC(=S)SSC(=S)OCC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sulfurous 73.31%
    Onion 63.93%
    Garlic 52.17%
    Alliaceous 45.31%
    Roasted 44.29%
    Savory 40.09%
    Meaty 37.05%
    Cooked 36.67%
    Fresh 32.71%
    Tropical 29.69%

     

    Flavor
    Fruity 44.63%
    Meaty 36.28%
    Cooked 35.63%
    Nutty 34.81%
    Sulfury 34.19%
    Cabbage 33.64%
    Onion 32.93%
    Roasted 32.7%
    Vegetable 27.64%
    Garlic 26.88%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    7.29 (neutral)

    Molecular weight
    242.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    289°C

    Flash point

    • 116.92 ˚C est.

  • Synonyms

    • Dixanthogen
    • 502-55-6
    • Diethyl dithiobis(thionoformate)
    • Bisethylxanthogen
    • BIS(ETHYLXANTHOGEN)
    • Dixanthogene
    • Dixantogeno
    • Dixanthogenum
    • DIETHYLDIXANTHOGEN
    • O,O-Diethyl dithiobis(thioformate)
    • Diexanthogen
    • Ethyl xanthogen disulfide
    • RN4CQ46FDM
    • NSC-402561
    • DTXSID2041672
    • DTXCID0021672
    • O,O-Diethyl dithiobis[thioformate]
    • Bis[ethylxanthogen]
    • RefChem:135279
    • O,O-diethyl dithiobisthioformate
    • P03AA01
    • ethoxy((ethoxymethanethioyl)disulfanyl)methanethione
    • 207-944-4
    • Auligen
    • Aulinogen
    • Scabicidol
    • Bexide
    • Herbisan
    • Lenisarin
    • Xantoscabin
    • Galasan
    • Dixan
    • K Preparation
    • Diethyl dixanthogen
    • Silfasan
    • Preparation K
    • Diethylxanthogen disulfide
    • Diethyl xanthogenate
    • Skabilan
    • Diethyl dixanthogenate
    • Xanthogen, bis(ethyl-
    • Diethylxanthic disulfide
    • EXD
    • Bis(ethylxanthic)disulfide
    • Bisethylxanthogen disulfide
    • Ethylxanthogen disulfide
    • Diethyldithiobis thionoformate
    • Diethyldithio bis(thionoformate)
    • Herbisan 5
    • Dithiobis(thioformic acid) O,O-diethyl ester
    • Di-ethoxythiokarbonyl-disulfid
    • NSC 402561
    • Formic acid, dithiobis(thio-, O,O-diethyl ester
    • O,O-Diethyl ester of dithiobis(thioformic acid)
    • O-ethyl (ethoxycarbothioyldisulfanyl)methanethioate
    • Thioperoxydicarbonic acid (((HO)C(S)S)2), diethyl ester
    • Dixanthogen (INN)
    • NSC402561
    • Thioperoxydicarbonic acid, diethyl ester
    • NCGC00160587-01
    • Thioperoxydicarbonic acid ([(HO)C(S)]2S2), diethyl ester
    • DIXANTHOGEN [INN]
    • Herbisan #5
    • Antigal (VAN)
    • Caswell No. 338
    • Thioperoxydicarbonic acid (((HO)C(S))2S2), diethyl ester
    • C6H10O2S4
    • Dixanthogen [INN:DCF]
    • Thioperoxydicarbonic acid (((HO)C(S))2S2), OC,OC'-diethyl ester
    • Dixantogeno [INN-Latin]
    • [[ethoxy(sulfanylidene)methyl]disulfanyl]methanethioic acid O-ethyl ester
    • Bis(ethylxanthic) disulfide
    • Dixanthogene [INN-French]
    • Dixanthogenum [INN-Latin]
    • CAS-502-55-6
    • Thioperoxydicarbonic acid diethyl ester
    • Ethylxanthic disulfide
    • Formic acid, dithiobis[thio-, O,O-diethyl ester
    • O,O-Diethyl ester of dithiobis[thioformic acid]
    • EINECS 207-944-4
    • UNII-RN4CQ46FDM
    • Di-ethoxythiokarbonyl-disulfid [Czech]
    • EPA Pesticide Chemical Code 086501
    • BRN 1781595
    • AI3-01649
    • BEXT (Salt/Mix)
    • Bisethylxanthic disulfide
    • DIXANTHOGEN [MI]
    • SCHEMBL37053
    • DIXANTHOGEN [WHO-DD]
    • 4-03-00-00416 (Beilstein Handbook Reference)
    • WLN: SUYO2&SSYUS&O2
    • CHEMBL331743
    • orb1309173
    • CHEBI:82241
    • Diethyl dithiobis(thiono formate)
    • HY-B1186
    • o,o-diethyl dithiobis-(thioformate)
    • Tox21_111916
    • Tox21_302227
    • EX-A11901
    • MFCD00022144
    • AKOS024333295
    • CCG-213902
    • CS-4795
    • DB13712
    • NCGC00255506-01
    • MS-23434
    • DB-051741
    • O,O-DIETHYL DITHIOBIS(THIONOFORMATE)
    • NS00022244
    • C19120
    • D07366
    • F85253
    • 1,1'-{Dithiobis[(thioxomethylene)oxy]}diethane
    • AB01563210_01
    • 1,1'-[disulfanediylbis(carbonothioyloxy)]diethane
    • 502B556
    • Q5284770
    • BRD-K05919151-001-01-6
    • 502-55-6

  • Applications

    Dixanthogen (CAS 502-55-6) is typically used as an intermediate in organosulfur chemistry, enabling the synthesis of sulfur-containing compounds. In industry it may serve as a reagent for the production of specialty polymers and rubber additives, and can function as a stabilizer or processing aid in plastics and coatings to improve thermal-oxidative stability and formulation compatibility. Related xanthogen disulfides and their derivatives are employed as flotation collectors or flotation aids in mineral processing, helping to separate target minerals from ore. Additionally, it can act as a crosslinking or curing agent in adhesive formulations under appropriate conditions. The exact use depends on formulation and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.99
    methanol 10.19
    isopropanol 7.0
    water 0.03
    ethyl acetate 129.29
    n-propanol 9.3
    acetone 175.22
    n-butanol 9.49
    acetonitrile 149.54
    DMF 385.09
    toluene 106.64
    isobutanol 7.71
    1,4-dioxane 208.31
    methyl acetate 169.63
    THF 347.36
    2-butanone 128.67
    n-pentanol 9.32
    sec-butanol 9.05
    n-hexane 5.47
    ethylene glycol 5.37
    NMP 858.52
    cyclohexane 20.06
    DMSO 392.45
    n-butyl acetate 115.05
    n-octanol 8.66
    chloroform 411.43
    n-propyl acetate 86.05
    acetic acid 61.88
    dichloromethane 459.72
    cyclohexanone 265.15
    propylene glycol 4.78
    isopropyl acetate 81.71
    DMAc 480.17
    2-ethoxyethanol 41.07
    isopentanol 10.58
    n-heptane 6.94
    ethyl formate 82.3
    1,2-dichloroethane 279.26
    n-hexanol 13.76
    2-methoxyethanol 63.18
    isobutyl acetate 52.03
    tetrachloromethane 53.28
    n-pentyl acetate 55.08
    transcutol 145.82
    n-heptanol 7.37
    ethylbenzene 56.59
    MIBK 60.04
    2-propoxyethanol 55.63
    tert-butanol 13.41
    MTBE 47.35
    2-butoxyethanol 29.31
    propionic acid 30.79
    o-xylene 73.95
    formic acid 21.64
    diethyl ether 48.92
    m-xylene 61.44
    p-xylene 80.63
    chlorobenzene 224.22
    dimethyl carbonate 112.81
    n-octane 2.86
    formamide 64.53
    cyclopentanone 419.19
    2-pentanone 91.5
    anisole 180.98
    cyclopentyl methyl ether 146.8
    gamma-butyrolactone 508.38
    1-methoxy-2-propanol 42.37
    pyridine 356.05
    3-pentanone 110.27
    furfural 711.33
    n-dodecane 2.58
    diethylene glycol 43.22
    diisopropyl ether 22.61
    tert-amyl alcohol 16.39
    acetylacetone 285.44
    n-hexadecane 3.28
    acetophenone 212.31
    methyl propionate 120.15
    isopentyl acetate 101.16
    trichloroethylene 766.21
    n-nonanol 9.77
    cyclohexanol 23.78
    benzyl alcohol 66.55
    2-ethylhexanol 19.05
    isooctanol 7.75
    dipropyl ether 50.63
    1,2-dichlorobenzene 275.59
    ethyl lactate 36.48
    propylene carbonate 242.59
    n-methylformamide 102.41
    2-pentanol 7.82
    n-pentane 4.06
    1-propoxy-2-propanol 45.19
    1-methoxy-2-propyl acetate 159.49
    2-(2-methoxypropoxy) propanol 73.59
    mesitylene 41.87
    ε-caprolactone 213.12
    p-cymene 47.21
    epichlorohydrin 517.79
    1,1,1-trichloroethane 285.48
    2-aminoethanol 8.08
    morpholine-4-carbaldehyde 548.17
    sulfolane 736.59
    2,2,4-trimethylpentane 4.2
    2-methyltetrahydrofuran 206.48
    n-hexyl acetate 62.79
    isooctane 2.71
    2-(2-butoxyethoxy)ethanol 58.83
    sec-butyl acetate 63.73
    tert-butyl acetate 108.1
    decalin 15.37
    glycerin 14.69
    diglyme 195.11
    acrylic acid 50.78
    isopropyl myristate 37.96
    n-butyric acid 41.1
    acetyl acetate 186.81
    di(2-ethylhexyl) phthalate 47.28
    ethyl propionate 96.76
    nitromethane 470.08
    1,2-diethoxyethane 102.75
    benzonitrile 169.6
    trioctyl phosphate 21.97
    1-bromopropane 83.57
    gamma-valerolactone 541.83
    n-decanol 8.15
    triethyl phosphate 83.57
    4-methyl-2-pentanol 7.06
    propionitrile 58.46
    vinylene carbonate 245.11
    1,1,2-trichlorotrifluoroethane 359.12
    DMS 187.24
    cumene 35.72
    2-octanol 6.04
    2-hexanone 75.01
    octyl acetate 42.04
    limonene 67.46
    1,2-dimethoxyethane 188.69
    ethyl orthosilicate 68.04
    tributyl phosphate 39.48
    diacetone alcohol 73.31
    N,N-dimethylaniline 136.63
    acrylonitrile 124.48
    aniline 84.38
    1,3-propanediol 12.24
    bromobenzene 296.83
    dibromomethane 228.74
    1,1,2,2-tetrachloroethane 465.03
    2-methyl-cyclohexyl acetate 116.36
    tetrabutyl urea 66.74
    diisobutyl methanol 14.69
    2-phenylethanol 70.56
    styrene 90.0
    dioctyl adipate 81.73
    dimethyl sulfate 304.82
    ethyl butyrate 110.06
    methyl lactate 52.86
    butyl lactate 35.37
    diethyl carbonate 89.88
    propanediol butyl ether 19.78
    triethyl orthoformate 84.89
    p-tert-butyltoluene 46.37
    methyl 4-tert-butylbenzoate 118.36
    morpholine 169.89
    tert-butylamine 9.14
    n-dodecanol 7.35
    dimethoxymethane 153.2
    ethylene carbonate 160.99
    cyrene 143.67
    2-ethoxyethyl acetate 110.69
    2-ethylhexyl acetate 98.15
    1,2,4-trichlorobenzene 357.0
    4-methylpyridine 313.5
    dibutyl ether 35.69
    2,6-dimethyl-4-heptanol 14.69
    DEF 191.02
    dimethyl isosorbide 288.26
    tetrachloroethylene 266.3
    eugenol 100.62
    triacetin 146.37
    span 80 50.05
    1,4-butanediol 6.41
    1,1-dichloroethane 166.05
    2-methyl-1-pentanol 11.92
    methyl formate 125.23
    2-methyl-1-butanol 10.32
    n-decane 3.78
    butyronitrile 51.03
    3,7-dimethyl-1-octanol 14.35
    1-chlorooctane 18.39
    1-chlorotetradecane 10.6
    n-nonane 3.32
    undecane 3.0
    tert-butylcyclohexane 9.56
    cyclooctane 8.41
    cyclopentanol 33.05
    tetrahydropyran 122.57
    tert-amyl methyl ether 53.32
    2,5,8-trioxanonane 161.13
    1-hexene 16.98
    2-isopropoxyethanol 31.76
    2,2,2-trifluoroethanol 47.74
    methyl butyrate 119.41

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction