Disulfide, ethyl 1-(propylthio)propyl

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  • Identifiers

    CAS number
    183554-24-7

    Molecular formula
    C8H18S3

    SMILES
    CCCSC(CC)SSCC

    Safety labels

  • Odor profile

    Fragrance
    Sulfurous 82.23%
    Onion 75.64%
    Alliaceous 71.85%
    Garlic 67.2%
    Green 63.56%
    Savory 54.74%
    Vegetable 51.0%
    Meaty 50.58%
    Roasted 48.59%
    Cooked 46.86%

     

    Flavor
    Onion 72.46%
    Sulfurous 66.8%
    Green 65.17%
    Garlic 64.18%
    Alliaceous 44.49%
    Metallic 37.99%
    Sulfury 33.6%
    Cabbage 29.36%
    Tropical 29.24%
    Cooked 26.77%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    4.98 (weak acid)

    Molecular weight
    210.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    259°C

    Flash point

    • 118.58 ˚C est.

  • Synonyms

    • Disulfide, ethyl 1-(propylthio)propyl
    • 183554-24-7
    • RefChem:339235
    • Ethyl 1-(propylthio)propyl disulfide
    • 1-(ethyldisulfanyl)-1-(propylsulfanyl)propane
    • CHEBI:174051
    • DTXSID101288650
    • 1-(ethyldisulanyl)-1-propylsulanylpropane
    • 183554-24-7

  • Applications

    Disulfide, ethyl 1-(propylthio)propyl (CAS 183554-24-7) is a sulfur-containing disulfide used primarily as an intermediate in organic synthesis and as a specialty additive in sulfur-containing formulations; in fragrance and cosmetics, it may serve as a fragrance component and sometimes as a fixative to extend scent longevity; in household, personal care, and cleaning products, it can contribute to odor profiles and formulation characteristics; in industrial manufacturing and polymers, it can act as a precursor to other sulfur-containing compounds or as a modifier/crosslinking-related ingredient to tailor polymer properties; in coatings, inks, and adhesives, it may participate in disulfide exchange or crosslinking under appropriate formulation conditions. Usage is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1846.01
    methanol 936.43
    isopropanol 1797.72
    water 0.05
    ethyl acetate 5324.69
    n-propanol 1801.31
    acetone 8858.78
    n-butanol 1937.51
    acetonitrile 3387.88
    DMF 7910.52
    toluene 5573.42
    isobutanol 1551.61
    1,4-dioxane 9626.3
    methyl acetate 4190.48
    THF 16020.22
    2-butanone 6584.48
    n-pentanol 1217.29
    sec-butanol 1733.49
    n-hexane 744.01
    ethylene glycol 160.34
    NMP 6909.22
    cyclohexane 3494.27
    DMSO 7602.97
    n-butyl acetate 6969.14
    n-octanol 1262.81
    chloroform 10573.9
    n-propyl acetate 3181.55
    acetic acid 1585.56
    dichloromethane 10417.29
    cyclohexanone 15604.35
    propylene glycol 361.38
    isopropyl acetate 3286.02
    DMAc 4457.18
    2-ethoxyethanol 1458.52
    isopentanol 1745.88
    n-heptane 1548.39
    ethyl formate 2663.31
    1,2-dichloroethane 7575.08
    n-hexanol 2241.24
    2-methoxyethanol 2520.47
    isobutyl acetate 1953.71
    tetrachloromethane 2383.91
    n-pentyl acetate 3236.48
    transcutol 5122.16
    n-heptanol 999.04
    ethylbenzene 1698.14
    MIBK 2890.67
    2-propoxyethanol 2699.96
    tert-butanol 2436.07
    MTBE 4061.1
    2-butoxyethanol 1486.17
    propionic acid 1511.95
    o-xylene 2293.55
    formic acid 150.6
    diethyl ether 5015.8
    m-xylene 2696.13
    p-xylene 2206.98
    chlorobenzene 5735.74
    dimethyl carbonate 1181.83
    n-octane 500.07
    formamide 425.34
    cyclopentanone 13895.38
    2-pentanone 6226.33
    anisole 2792.81
    cyclopentyl methyl ether 7213.11
    gamma-butyrolactone 9388.95
    1-methoxy-2-propanol 2067.63
    pyridine 10466.64
    3-pentanone 4520.12
    furfural 6830.68
    n-dodecane 277.2
    diethylene glycol 1068.9
    diisopropyl ether 1668.47
    tert-amyl alcohol 1962.19
    acetylacetone 6070.32
    n-hexadecane 339.82
    acetophenone 2617.93
    methyl propionate 3451.8
    isopentyl acetate 4728.88
    trichloroethylene 13770.8
    n-nonanol 1060.94
    cyclohexanol 3923.76
    benzyl alcohol 1609.73
    2-ethylhexanol 1874.71
    isooctanol 856.19
    dipropyl ether 4488.49
    1,2-dichlorobenzene 4149.2
    ethyl lactate 731.61
    propylene carbonate 4643.59
    n-methylformamide 2111.72
    2-pentanol 1555.76
    n-pentane 808.07
    1-propoxy-2-propanol 2655.09
    1-methoxy-2-propyl acetate 3753.07
    2-(2-methoxypropoxy) propanol 1246.7
    mesitylene 1689.62
    ε-caprolactone 8285.3
    p-cymene 1493.98
    epichlorohydrin 9132.97
    1,1,1-trichloroethane 8921.84
    2-aminoethanol 413.3
    morpholine-4-carbaldehyde 6636.13
    sulfolane 10035.58
    2,2,4-trimethylpentane 332.71
    2-methyltetrahydrofuran 11026.41
    n-hexyl acetate 3574.38
    isooctane 323.01
    2-(2-butoxyethoxy)ethanol 1802.67
    sec-butyl acetate 1952.27
    tert-butyl acetate 3663.67
    decalin 763.8
    glycerin 408.75
    diglyme 4378.29
    acrylic acid 1154.1
    isopropyl myristate 1415.31
    n-butyric acid 3081.53
    acetyl acetate 2828.8
    di(2-ethylhexyl) phthalate 932.06
    ethyl propionate 2364.42
    nitromethane 4184.42
    1,2-diethoxyethane 4598.0
    benzonitrile 4091.47
    trioctyl phosphate 775.3
    1-bromopropane 5182.78
    gamma-valerolactone 12736.08
    n-decanol 769.91
    triethyl phosphate 1196.51
    4-methyl-2-pentanol 854.19
    propionitrile 3086.09
    vinylene carbonate 3944.83
    1,1,2-trichlorotrifluoroethane 3535.52
    DMS 2060.77
    cumene 867.31
    2-octanol 935.54
    2-hexanone 3494.55
    octyl acetate 1608.59
    limonene 3041.05
    1,2-dimethoxyethane 4943.55
    ethyl orthosilicate 1190.25
    tributyl phosphate 1043.38
    diacetone alcohol 2469.88
    N,N-dimethylaniline 1582.68
    acrylonitrile 3377.88
    aniline 3273.73
    1,3-propanediol 913.72
    bromobenzene 7384.55
    dibromomethane 7379.71
    1,1,2,2-tetrachloroethane 9422.17
    2-methyl-cyclohexyl acetate 2398.22
    tetrabutyl urea 1510.58
    diisobutyl methanol 1336.45
    2-phenylethanol 2006.09
    styrene 2582.87
    dioctyl adipate 1714.23
    dimethyl sulfate 1786.74
    ethyl butyrate 3913.01
    methyl lactate 862.93
    butyl lactate 1552.42
    diethyl carbonate 2013.26
    propanediol butyl ether 1248.52
    triethyl orthoformate 2482.31
    p-tert-butyltoluene 1474.44
    methyl 4-tert-butylbenzoate 1735.79
    morpholine 9481.22
    tert-butylamine 1638.84
    n-dodecanol 623.94
    dimethoxymethane 4069.55
    ethylene carbonate 3720.3
    cyrene 1452.26
    2-ethoxyethyl acetate 3334.01
    2-ethylhexyl acetate 4196.66
    1,2,4-trichlorobenzene 4147.54
    4-methylpyridine 10303.0
    dibutyl ether 3520.76
    2,6-dimethyl-4-heptanol 1336.45
    DEF 5562.54
    dimethyl isosorbide 3373.93
    tetrachloroethylene 5640.57
    eugenol 1391.94
    triacetin 2213.12
    span 80 1585.52
    1,4-butanediol 368.92
    1,1-dichloroethane 7622.74
    2-methyl-1-pentanol 1057.23
    methyl formate 1924.39
    2-methyl-1-butanol 1570.32
    n-decane 551.88
    butyronitrile 4178.19
    3,7-dimethyl-1-octanol 1300.59
    1-chlorooctane 1719.64
    1-chlorotetradecane 635.06
    n-nonane 637.72
    undecane 364.82
    tert-butylcyclohexane 534.02
    cyclooctane 1139.46
    cyclopentanol 3524.62
    tetrahydropyran 13329.33
    tert-amyl methyl ether 2699.16
    2,5,8-trioxanonane 2491.21
    1-hexene 2135.51
    2-isopropoxyethanol 1113.31
    2,2,2-trifluoroethanol 453.26
    methyl butyrate 3679.63

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction