Disodium Stearoyl Glutamate

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  • Identifiers

    CAS number
    38079-62-8

    Molecular formula
    C23H41NNa2O5

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 45.86%
    Waxy 34.0%
    Fatty 33.21%
    Savory 33.1%
    Meaty 25.59%
    Oily 25.14%
    Milky 22.54%
    Cooling 21.56%
    Animal 20.44%
    Fishy 20.04%

     

    Flavor
    Odorless 42.7%
    Bland 38.65%
    Mild 30.68%
    Faint 23.56%
    Bitter 22.62%
    Slightly waxy 20.98%
    Herbal 20.43%
    Bay oil 20.04%
    Cedarleaf 19.48%
    Sweet-like 19.3%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.73 (weak acid)

    Molecular weight
    457.6 g/mol

    Flash point

    • 254.74 ˚C est.

  • Synonyms

    • Disodium stearoyl glutamate
    • 38079-62-8
    • EINECS 253-773-3
    • UNII-45ASM2L11M
    • Amisoft HS-21
    • 45ASM2L11M
    • L-Glutamic acid, N-(1-oxooctadecyl)-, disodium salt
    • disodium stearoylglutamate
    • L-Glutamic acid, N-(1-oxooctadecyl)-, sodium salt (1:2)
    • AMISOFT HS 21P
    • AMISOFT HS-21P
    • N-Stearoylglutamic acid disodium salt
    • AMISOFT HS 21
    • disodium n-stearoylglutamate
    • ACYLGLUTAMATE HS 21
    • ACYLGLUTAMATE HS-21
    • AMISOFT HS-21(P)
    • disodium stearoyl-L-glutamate
    • sodium n-stearoyl-l-glutamate
    • disodium n-stearoyl-l-glutamate
    • DTXSID50889726
    • n-stearoyl-l-glutamic acid disodium salt
    • L-GLUTAMIC ACID, N-(1-OXOOCTADAECYL)-, DISODIUM SALT
    • RefChem:135085
    • DTXCID201028978
    • DISODIUM STEAROYL GLUTAMATE [INCI]
    • 253-773-3
    • Disodium N-(1-oxooctadecyl)-L-glutamate
    • disodium;(2S)-2-(octadecanoylamino)pentanedioate
    • SCHEMBL156488
    • sodium N-stearoyl-l-glu tamate
    • NS00088366
    • DISODIUM (2S)-2-OCTADECANAMIDOPENTANEDIOATE
    • Q27258828
    • 38079-62-8

  • Applications

    Disodium Stearoyl Glutamate (CAS 38079-62-8) is used primarily as a mild surfactant and emulsifier in cosmetic and personal care formulations, stabilizing oil‑in‑water emulsions in products such as creams, lotions, cleansers and shampoos, and it can also function as a texture modifier and conditioning agent. It is also employed in household cleaning products as a gentle surfactant. In industrial manufacturing, it serves as an emulsifier and dispersing aid in polymer formulations and in coatings/inks to improve pigment dispersion, wetting and stability. Across these domains, its role is as a surfactant, emulsifier and texture modifier, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.38
    methanol 11.81
    isopropanol 3.98
    water 0.38
    ethyl acetate 7.92
    n-propanol 5.6
    acetone 16.42
    n-butanol 4.21
    acetonitrile 4.85
    DMF 81.25
    toluene 4.13
    isobutanol 3.92
    1,4-dioxane 16.8
    methyl acetate 11.49
    THF 46.27
    2-butanone 16.1
    n-pentanol 5.49
    sec-butanol 5.37
    n-hexane 0.82
    ethylene glycol 2.2
    NMP 181.91
    cyclohexane 1.11
    DMSO 129.8
    n-butyl acetate 9.59
    n-octanol 5.47
    chloroform 22.07
    n-propyl acetate 12.83
    acetic acid 23.22
    dichloromethane 26.3
    cyclohexanone 39.82
    propylene glycol 4.52
    isopropyl acetate 8.43
    DMAc 178.33
    2-ethoxyethanol 20.96
    isopentanol 4.26
    n-heptane 0.51
    ethyl formate 9.45
    1,2-dichloroethane 17.3
    n-hexanol 3.34
    2-methoxyethanol 21.29
    isobutyl acetate 7.78
    tetrachloromethane 5.8
    n-pentyl acetate 17.47
    transcutol 91.09
    n-heptanol 5.03
    ethylbenzene 4.53
    MIBK 8.93
    2-propoxyethanol 16.19
    tert-butanol 6.87
    MTBE 7.62
    2-butoxyethanol 21.48
    propionic acid 14.31
    o-xylene 6.48
    formic acid 14.46
    diethyl ether 4.0
    m-xylene 3.88
    p-xylene 6.68
    chlorobenzene 6.66
    dimethyl carbonate 10.04
    n-octane 0.47
    formamide 24.72
    cyclopentanone 51.42
    2-pentanone 10.5
    anisole 10.22
    cyclopentyl methyl ether 15.05
    gamma-butyrolactone 65.05
    1-methoxy-2-propanol 18.42
    pyridine 20.02
    3-pentanone 12.02
    furfural 57.6
    n-dodecane 0.32
    diethylene glycol 11.82
    diisopropyl ether 2.32
    tert-amyl alcohol 9.54
    acetylacetone 22.64
    n-hexadecane 0.36
    acetophenone 20.69
    methyl propionate 12.21
    isopentyl acetate 10.54
    trichloroethylene 36.01
    n-nonanol 5.74
    cyclohexanol 8.21
    benzyl alcohol 10.14
    2-ethylhexanol 3.38
    isooctanol 4.83
    dipropyl ether 4.89
    1,2-dichlorobenzene 10.86
    ethyl lactate 12.77
    propylene carbonate 33.42
    n-methylformamide 24.85
    2-pentanol 3.17
    n-pentane 0.42
    1-propoxy-2-propanol 14.35
    1-methoxy-2-propyl acetate 16.86
    2-(2-methoxypropoxy) propanol 28.74
    mesitylene 3.16
    ε-caprolactone 43.18
    p-cymene 3.32
    epichlorohydrin 42.77
    1,1,1-trichloroethane 16.22
    2-aminoethanol 5.83
    morpholine-4-carbaldehyde 80.45
    sulfolane 169.1
    2,2,4-trimethylpentane 0.81
    2-methyltetrahydrofuran 22.76
    n-hexyl acetate 18.57
    isooctane 0.3
    2-(2-butoxyethoxy)ethanol 32.33
    sec-butyl acetate 9.58
    tert-butyl acetate 14.54
    decalin 1.34
    glycerin 10.56
    diglyme 70.08
    acrylic acid 15.44
    isopropyl myristate 5.87
    n-butyric acid 15.16
    acetyl acetate 9.62
    di(2-ethylhexyl) phthalate 9.98
    ethyl propionate 11.34
    nitromethane 42.39
    1,2-diethoxyethane 17.92
    benzonitrile 9.28
    trioctyl phosphate 6.28
    1-bromopropane 6.13
    gamma-valerolactone 86.25
    n-decanol 3.63
    triethyl phosphate 11.52
    4-methyl-2-pentanol 2.69
    propionitrile 4.8
    vinylene carbonate 27.0
    1,1,2-trichlorotrifluoroethane 55.56
    DMS 18.62
    cumene 4.02
    2-octanol 4.26
    2-hexanone 13.89
    octyl acetate 8.66
    limonene 4.87
    1,2-dimethoxyethane 37.29
    ethyl orthosilicate 10.81
    tributyl phosphate 8.7
    diacetone alcohol 22.28
    N,N-dimethylaniline 11.96
    acrylonitrile 7.51
    aniline 6.59
    1,3-propanediol 7.07
    bromobenzene 6.82
    dibromomethane 13.87
    1,1,2,2-tetrachloroethane 38.85
    2-methyl-cyclohexyl acetate 13.54
    tetrabutyl urea 15.89
    diisobutyl methanol 2.78
    2-phenylethanol 7.56
    styrene 4.6
    dioctyl adipate 14.78
    dimethyl sulfate 41.28
    ethyl butyrate 10.3
    methyl lactate 14.98
    butyl lactate 20.88
    diethyl carbonate 7.84
    propanediol butyl ether 22.27
    triethyl orthoformate 11.75
    p-tert-butyltoluene 3.27
    methyl 4-tert-butylbenzoate 29.41
    morpholine 25.25
    tert-butylamine 3.83
    n-dodecanol 2.45
    dimethoxymethane 21.91
    ethylene carbonate 20.22
    cyrene 37.12
    2-ethoxyethyl acetate 27.2
    2-ethylhexyl acetate 8.98
    1,2,4-trichlorobenzene 16.27
    4-methylpyridine 16.97
    dibutyl ether 7.13
    2,6-dimethyl-4-heptanol 2.78
    DEF 27.6
    dimethyl isosorbide 54.14
    tetrachloroethylene 26.04
    eugenol 26.52
    triacetin 37.33
    span 80 21.17
    1,4-butanediol 4.89
    1,1-dichloroethane 11.03
    2-methyl-1-pentanol 5.94
    methyl formate 16.45
    2-methyl-1-butanol 4.95
    n-decane 0.71
    butyronitrile 4.69
    3,7-dimethyl-1-octanol 4.9
    1-chlorooctane 3.85
    1-chlorotetradecane 1.22
    n-nonane 0.64
    undecane 0.45
    tert-butylcyclohexane 1.08
    cyclooctane 0.48
    cyclopentanol 10.94
    tetrahydropyran 13.33
    tert-amyl methyl ether 9.36
    2,5,8-trioxanonane 48.07
    1-hexene 2.5
    2-isopropoxyethanol 14.97
    2,2,2-trifluoroethanol 16.89
    methyl butyrate 18.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction