Disodium Lauroyl Glutamate

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  • Identifiers

    CAS number
    50622-20-3

    Molecular formula
    C17H29NNa2O5

    SMILES
    CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 49.76%
    Savory 36.71%
    Fatty 26.83%
    Meaty 26.55%
    Cooling 25.85%
    Milky 24.48%
    Oily 23.32%
    Waxy 20.74%
    Lactonic 19.98%
    Herbal 19.44%

     

    Flavor
    Odorless 47.42%
    Bland 35.99%
    Mild 29.8%
    Bitter 28.07%
    Faint 20.81%
    Sweet-like 20.26%
    Slightly waxy 19.89%
    Bay oil 19.65%
    Cedarleaf 19.37%
    Herbal 19.07%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    2.83 (strong acid)

    Molecular weight
    373.4 g/mol

    Flash point

    • 235.93 ˚C est.

  • Synonyms

    • Disodium lauroyl glutamate
    • L-Glutamic acid, N-(1-oxododecyl)-, disodium salt
    • 50622-20-3
    • UNII-O99ROV57IA
    • O99ROV57IA
    • L-Glutamic acid, N-(1-oxododecyl)-, sodium salt (1:2)
    • AMISOFT LS 22
    • AMISOFT LS-22
    • DTXSID7074824
    • DISODIUM LAUROYL-L-GLUTAMATE
    • N-Lauroylglutamic acid disodium salt
    • N-LAUROYL-L-GLUTAMIC ACID DISODIUM SALT
    • RefChem:135056
    • DTXCID1040875
    • DISODIUM LAUROYL GLUTAMATE [INCI]
    • disodium;(2S)-2-(dodecanoylamino)pentanedioate
    • Sodium N-dodecanoyl-L-glutamate
    • SCHEMBL109347
    • 51959-34-3
    • DB-254552
    • Disodium (2s)-2-(dodecanoylamino)pentanedioate
    • DISODIUM (2S)-2-DODECANAMIDOPENTANEDIOATE
    • Q27285514
    • 50622-20-3

  • Applications

    Disodium Lauroyl Glutamate (CAS 50622-20-3) is a mild amino-acid–based surfactant used primarily as a cleansing and emulsifying agent in cosmetics and personal care products, such as shampoos, facial cleansers, and body washes. It also serves as an emulsifier and conditioning helper in formulations, contributing to texture and spreadability in skin and hair care products. In household cleaning products, it functions as a gentle surfactant and foaming agent in dish liquids and general cleaners. In industrial cleaning applications, it is employed as a biodegradable surfactant in degreasers and institutional cleaners. In pharmaceutical formulations, it may be used as an excipient/surfactant in topical or oral products, depending on formulation requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 31.21
    methanol 77.26
    isopropanol 18.01
    water 0.43
    ethyl acetate 19.48
    n-propanol 21.67
    acetone 59.24
    n-butanol 14.71
    acetonitrile 14.23
    DMF 318.28
    toluene 6.55
    isobutanol 13.54
    1,4-dioxane 38.91
    methyl acetate 28.05
    THF 92.36
    2-butanone 36.56
    n-pentanol 18.39
    sec-butanol 16.81
    n-hexane 0.73
    ethylene glycol 11.41
    NMP 344.96
    cyclohexane 0.69
    DMSO 574.05
    n-butyl acetate 18.88
    n-octanol 8.72
    chloroform 26.25
    n-propyl acetate 23.58
    acetic acid 82.1
    dichloromethane 35.71
    cyclohexanone 79.16
    propylene glycol 21.33
    isopropyl acetate 19.61
    DMAc 454.97
    2-ethoxyethanol 71.66
    isopentanol 14.96
    n-heptane 0.34
    ethyl formate 22.29
    1,2-dichloroethane 32.74
    n-hexanol 9.84
    2-methoxyethanol 91.62
    isobutyl acetate 14.1
    tetrachloromethane 4.62
    n-pentyl acetate 21.01
    transcutol 223.51
    n-heptanol 8.71
    ethylbenzene 7.11
    MIBK 21.42
    2-propoxyethanol 48.01
    tert-butanol 27.9
    MTBE 16.65
    2-butoxyethanol 36.8
    propionic acid 40.21
    o-xylene 10.95
    formic acid 64.81
    diethyl ether 8.65
    m-xylene 7.25
    p-xylene 10.05
    chlorobenzene 10.96
    dimethyl carbonate 23.08
    n-octane 0.35
    formamide 109.11
    cyclopentanone 108.83
    2-pentanone 26.88
    anisole 21.59
    cyclopentyl methyl ether 26.42
    gamma-butyrolactone 136.07
    1-methoxy-2-propanol 67.4
    pyridine 38.68
    3-pentanone 22.31
    furfural 122.31
    n-dodecane 0.33
    diethylene glycol 47.55
    diisopropyl ether 3.82
    tert-amyl alcohol 27.66
    acetylacetone 64.33
    n-hexadecane 0.38
    acetophenone 40.84
    methyl propionate 27.43
    isopentyl acetate 20.74
    trichloroethylene 58.45
    n-nonanol 8.9
    cyclohexanol 17.76
    benzyl alcohol 26.88
    2-ethylhexanol 6.65
    isooctanol 8.05
    dipropyl ether 6.46
    1,2-dichlorobenzene 16.36
    ethyl lactate 25.14
    propylene carbonate 62.38
    n-methylformamide 90.61
    2-pentanol 9.01
    n-pentane 0.36
    1-propoxy-2-propanol 31.32
    1-methoxy-2-propyl acetate 36.48
    2-(2-methoxypropoxy) propanol 55.52
    mesitylene 5.5
    ε-caprolactone 78.95
    p-cymene 4.72
    epichlorohydrin 93.96
    1,1,1-trichloroethane 19.04
    2-aminoethanol 30.03
    morpholine-4-carbaldehyde 197.41
    sulfolane 312.03
    2,2,4-trimethylpentane 0.78
    2-methyltetrahydrofuran 42.15
    n-hexyl acetate 25.29
    isooctane 0.39
    2-(2-butoxyethoxy)ethanol 68.15
    sec-butyl acetate 16.49
    tert-butyl acetate 30.1
    decalin 1.32
    glycerin 42.82
    diglyme 128.98
    acrylic acid 45.78
    isopropyl myristate 9.12
    n-butyric acid 39.27
    acetyl acetate 23.28
    di(2-ethylhexyl) phthalate 17.11
    ethyl propionate 19.95
    nitromethane 148.33
    1,2-diethoxyethane 33.16
    benzonitrile 21.73
    trioctyl phosphate 9.8
    1-bromopropane 9.46
    gamma-valerolactone 188.36
    n-decanol 6.09
    triethyl phosphate 15.99
    4-methyl-2-pentanol 7.23
    propionitrile 11.09
    vinylene carbonate 51.37
    1,1,2-trichlorotrifluoroethane 115.74
    DMS 33.97
    cumene 6.19
    2-octanol 6.15
    2-hexanone 27.18
    octyl acetate 13.12
    limonene 6.68
    1,2-dimethoxyethane 100.12
    ethyl orthosilicate 14.96
    tributyl phosphate 14.06
    diacetone alcohol 56.62
    N,N-dimethylaniline 22.75
    acrylonitrile 20.8
    aniline 15.71
    1,3-propanediol 33.86
    bromobenzene 9.73
    dibromomethane 17.68
    1,1,2,2-tetrachloroethane 59.41
    2-methyl-cyclohexyl acetate 20.88
    tetrabutyl urea 24.05
    diisobutyl methanol 4.95
    2-phenylethanol 18.39
    styrene 8.01
    dioctyl adipate 22.92
    dimethyl sulfate 81.75
    ethyl butyrate 16.31
    methyl lactate 38.48
    butyl lactate 30.06
    diethyl carbonate 12.58
    propanediol butyl ether 45.72
    triethyl orthoformate 15.76
    p-tert-butyltoluene 4.66
    methyl 4-tert-butylbenzoate 47.1
    morpholine 63.03
    tert-butylamine 10.84
    n-dodecanol 4.3
    dimethoxymethane 71.97
    ethylene carbonate 37.76
    cyrene 71.96
    2-ethoxyethyl acetate 41.43
    2-ethylhexyl acetate 15.18
    1,2,4-trichlorobenzene 24.6
    4-methylpyridine 38.3
    dibutyl ether 9.3
    2,6-dimethyl-4-heptanol 4.95
    DEF 66.11
    dimethyl isosorbide 94.02
    tetrachloroethylene 36.4
    eugenol 44.41
    triacetin 55.54
    span 80 40.13
    1,4-butanediol 20.96
    1,1-dichloroethane 17.15
    2-methyl-1-pentanol 18.38
    methyl formate 54.32
    2-methyl-1-butanol 15.79
    n-decane 0.62
    butyronitrile 11.66
    3,7-dimethyl-1-octanol 8.86
    1-chlorooctane 3.93
    1-chlorotetradecane 1.49
    n-nonane 0.52
    undecane 0.43
    tert-butylcyclohexane 1.1
    cyclooctane 0.34
    cyclopentanol 25.62
    tetrahydropyran 22.55
    tert-amyl methyl ether 18.11
    2,5,8-trioxanonane 99.27
    1-hexene 3.72
    2-isopropoxyethanol 44.77
    2,2,2-trifluoroethanol 40.08
    methyl butyrate 33.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction