Disodium Capryloyl Glutamate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    167888-81-5

    Molecular formula
    C13H21NNa2O5

    SMILES
    CCCCCCCC(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 52.68%
    Savory 38.18%
    Cooling 26.76%
    Meaty 26.18%
    Milky 24.73%
    Fatty 22.19%
    Oily 22.03%
    Sweet 20.25%
    Herbal 19.98%
    Lactonic 19.56%

     

    Flavor
    Odorless 52.13%
    Bland 31.96%
    Bitter 29.29%
    Mild 28.85%
    Sweet-like 20.96%
    Faint 19.35%
    Nitrile 19.0%
    Bay oil 18.97%
    Slightly waxy 18.83%
    Cedarleaf 18.76%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    2.53 (strong acid)

    Molecular weight
    317.29 g/mol

    Flash point

    • 226.79 ˚C est.

  • Synonyms

    • Emulvama AGW
    • Disodium capryloyl glutamate
    • UNII-MCG3T4GPL4
    • MCG3T4GPL4
    • L-Glutamic acid, N-(1-oxooctyl)-, disodium salt
    • L-Glutamic acid, N-(1-oxooctyl)-, sodium salt (1:2)
    • 167888-81-5
    • DTXSID50168422
    • RefChem:135017
    • DTXCID5090913
    • DISODIUM CAPRYLOYL GLUTAMATE [INCI]
    • 605-493-1
    • Protelan AG 8
    • SCHEMBL531277
    • Disodium (2S)-2-octanamidopentanedioate
    • Q27283888
    • 167888-81-5

  • Applications

    Disodium Capryloyl Glutamate (CAS 167888-81-5) is primarily used in cosmetics and personal care as a mild anionic surfactant and emulsifier derived from glutamic acid and caprylic acid. In formulations for cleansers, shampoos, and facial care products it provides cleansing action with gentle foaming while helping to stabilize emulsions and improve texture. It can function as a co-surfactant and conditioning aid, contributing to skin feel and rinse-off performance. In coatings and inks, it can act as a surfactant/emulsifier to improve pigment dispersion and formulation stability. Beyond cosmetics, it is encountered in household cleaners and industrial cleaning formulations where its mild surfactant properties support dirt removal and formulation stability. Due to its amino-acid origin, it is often evaluated as a more skin-friendly alternative to harsher surfactants, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 103.92
    methanol 270.29
    isopropanol 43.11
    water 2.65
    ethyl acetate 35.22
    n-propanol 54.69
    acetone 135.47
    n-butanol 35.07
    acetonitrile 31.29
    DMF 837.71
    toluene 6.72
    isobutanol 30.67
    1,4-dioxane 63.3
    methyl acetate 46.86
    THF 112.77
    2-butanone 55.43
    n-pentanol 34.76
    sec-butanol 33.24
    n-hexane 0.82
    ethylene glycol 60.31
    NMP 520.27
    cyclohexane 0.6
    DMSO 1401.93
    n-butyl acetate 24.13
    n-octanol 9.35
    chloroform 21.9
    n-propyl acetate 25.58
    acetic acid 230.96
    dichloromethane 35.47
    cyclohexanone 96.56
    propylene glycol 68.23
    isopropyl acetate 25.55
    DMAc 751.56
    2-ethoxyethanol 139.5
    isopentanol 30.82
    n-heptane 0.32
    ethyl formate 40.91
    1,2-dichloroethane 38.7
    n-hexanol 17.8
    2-methoxyethanol 241.29
    isobutyl acetate 13.67
    tetrachloromethane 3.54
    n-pentyl acetate 18.18
    transcutol 340.14
    n-heptanol 10.13
    ethylbenzene 7.06
    MIBK 28.12
    2-propoxyethanol 83.43
    tert-butanol 58.46
    MTBE 22.47
    2-butoxyethanol 43.21
    propionic acid 82.45
    o-xylene 11.78
    formic acid 249.13
    diethyl ether 13.93
    m-xylene 7.86
    p-xylene 10.06
    chlorobenzene 12.12
    dimethyl carbonate 41.95
    n-octane 0.3
    formamide 348.22
    cyclopentanone 140.74
    2-pentanone 41.6
    anisole 27.66
    cyclopentyl methyl ether 30.8
    gamma-butyrolactone 198.1
    1-methoxy-2-propanol 144.68
    pyridine 52.61
    3-pentanone 29.21
    furfural 186.61
    n-dodecane 0.3
    diethylene glycol 110.19
    diisopropyl ether 4.48
    tert-amyl alcohol 50.41
    acetylacetone 96.82
    n-hexadecane 0.35
    acetophenone 48.51
    methyl propionate 48.32
    isopentyl acetate 25.08
    trichloroethylene 64.5
    n-nonanol 9.28
    cyclohexanol 25.47
    benzyl alcohol 42.9
    2-ethylhexanol 8.83
    isooctanol 8.71
    dipropyl ether 6.52
    1,2-dichlorobenzene 16.63
    ethyl lactate 33.45
    propylene carbonate 83.33
    n-methylformamide 246.65
    2-pentanol 16.57
    n-pentane 0.45
    1-propoxy-2-propanol 45.2
    1-methoxy-2-propyl acetate 47.62
    2-(2-methoxypropoxy) propanol 71.0
    mesitylene 5.74
    ε-caprolactone 91.38
    p-cymene 4.79
    epichlorohydrin 145.35
    1,1,1-trichloroethane 16.51
    2-aminoethanol 105.21
    morpholine-4-carbaldehyde 332.92
    sulfolane 417.24
    2,2,4-trimethylpentane 0.75
    2-methyltetrahydrofuran 51.59
    n-hexyl acetate 24.77
    isooctane 0.4
    2-(2-butoxyethoxy)ethanol 91.84
    sec-butyl acetate 16.48
    tert-butyl acetate 36.69
    decalin 1.09
    glycerin 131.77
    diglyme 158.2
    acrylic acid 105.43
    isopropyl myristate 8.65
    n-butyric acid 69.19
    acetyl acetate 35.68
    di(2-ethylhexyl) phthalate 20.25
    ethyl propionate 22.91
    nitromethane 368.89
    1,2-diethoxyethane 38.67
    benzonitrile 31.54
    trioctyl phosphate 11.02
    1-bromopropane 9.54
    gamma-valerolactone 256.98
    n-decanol 6.78
    triethyl phosphate 17.08
    4-methyl-2-pentanol 11.19
    propionitrile 19.04
    vinylene carbonate 76.65
    1,1,2-trichlorotrifluoroethane 169.84
    DMS 43.15
    cumene 6.07
    2-octanol 6.38
    2-hexanone 29.34
    octyl acetate 13.2
    limonene 6.41
    1,2-dimethoxyethane 159.47
    ethyl orthosilicate 15.24
    tributyl phosphate 16.21
    diacetone alcohol 82.58
    N,N-dimethylaniline 29.18
    acrylonitrile 41.26
    aniline 22.57
    1,3-propanediol 98.0
    bromobenzene 9.78
    dibromomethane 17.53
    1,1,2,2-tetrachloroethane 59.43
    2-methyl-cyclohexyl acetate 21.65
    tetrabutyl urea 26.97
    diisobutyl methanol 5.83
    2-phenylethanol 26.24
    styrene 8.21
    dioctyl adipate 23.3
    dimethyl sulfate 139.3
    ethyl butyrate 17.71
    methyl lactate 69.96
    butyl lactate 31.8
    diethyl carbonate 14.73
    propanediol butyl ether 63.26
    triethyl orthoformate 15.89
    p-tert-butyltoluene 4.57
    methyl 4-tert-butylbenzoate 48.85
    morpholine 105.15
    tert-butylamine 18.32
    n-dodecanol 4.91
    dimethoxymethane 155.9
    ethylene carbonate 53.3
    cyrene 93.57
    2-ethoxyethyl acetate 43.22
    2-ethylhexyl acetate 16.43
    1,2,4-trichlorobenzene 25.12
    4-methylpyridine 55.72
    dibutyl ether 8.34
    2,6-dimethyl-4-heptanol 5.83
    DEF 109.98
    dimethyl isosorbide 111.09
    tetrachloroethylene 35.19
    eugenol 50.19
    triacetin 56.99
    span 80 51.92
    1,4-butanediol 55.22
    1,1-dichloroethane 17.23
    2-methyl-1-pentanol 30.48
    methyl formate 147.72
    2-methyl-1-butanol 31.0
    n-decane 0.5
    butyronitrile 17.86
    3,7-dimethyl-1-octanol 10.31
    1-chlorooctane 3.17
    1-chlorotetradecane 1.42
    n-nonane 0.43
    undecane 0.38
    tert-butylcyclohexane 0.94
    cyclooctane 0.31
    cyclopentanol 38.33
    tetrahydropyran 26.15
    tert-amyl methyl ether 24.45
    2,5,8-trioxanonane 127.79
    1-hexene 4.11
    2-isopropoxyethanol 72.35
    2,2,2-trifluoroethanol 87.02
    methyl butyrate 39.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction