Dipropyl Adipate

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  • Identifiers

    CAS number
    106-19-4

    Molecular formula
    C12H22O4

    SMILES
    CCCOC(=O)CCCCC(=O)OCCC

  • Odor profile

    Fragrance
    Fruity 65.57%
    Winey 50.28%
    Oily 42.36%
    Fatty 39.23%
    Buttery 28.5%
    Ethereal 28.49%
    Odorless 27.39%
    Sweet 26.59%
    Fermented 25.42%
    Apple 24.73%

     

    Flavor
    Fruity 86.55%
    Pineapple 65.06%
    Sweet 64.55%
    Apple 56.48%
    Fruit 50.19%
    Green 45.51%
    Tropical 43.57%
    Berry 43.21%
    Grape 41.41%
    Wine 40.35%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    7.85 (neutral)

    Molecular weight
    230.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • -20 °C

    Boiling point

    • 273.00 to 274.00 °C. @ 760.00 mm Hg

    Flash point

    • 128.6 ˚C est.

    Solubility expt.

    • very slightly
    • Very slightly soluble in water
    • Soluble (in ethanol)

  • Synonyms

    • Dipropyl adipate
    • 106-19-4
    • DIPROPYL HEXANEDIOATE
    • Adipic acid, dipropyl ester
    • Hexanedioic acid, dipropyl ester
    • Di-n-propyl adipate
    • Adipic acid di-n-propyl ester
    • Adipic acid, di-n-propyl ester
    • 1,6-dipropyl hexanedioate
    • NSC 4894
    • EINECS 203-371-9
    • UNII-WB3LW508W0
    • BRN 1785512
    • WB3LW508W0
    • DTXSID6044511
    • AI3-06052
    • NSC-4894
    • Hexanedioic acid, 1,6-dipropyl ester
    • DTXCID4024511
    • FEMA NO. 4473
    • MFCD00048696
    • DIPROPYLADIPATE
    • Dipropyl hexanedioate #
    • Adipic Acid Dipropyl Ester
    • SCHEMBL33810
    • hexanedioic acid dipropyl ester
    • DIPROPYL ADIPATE [INCI]
    • CHEMBL3187954
    • Adipic acid, bis-n-propyl ester
    • NSC4894
    • CHEBI:169438
    • Tox21_301168
    • LMFA07010841
    • AKOS015839643
    • NCGC00248313-01
    • NCGC00255066-01
    • CAS-106-19-4
    • A0931
    • CS-0206774
    • NS00013608
    • D88357
    • Q27292539
    • Z1137991854
    • 203-371-9

  • Applications

    Dipropyl Adipate (CAS 106-19-4) is commonly used as an emollient and solvent in cosmetics and personal care, providing slip and moisturization while serving as a solvent for fragrance oils and active ingredients in formulations. In polymer and plastics applications, it acts as a plasticizer for PVC and other resins, improving flexibility and processing. In perfumery, it serves as a fragrance solvent/carrier for fragrance materials. As an industrial processing aid, it can function as a solvent and carrier in manufacturing formulations, coatings, and inks. Depending on local regulations and formulation limits, it is used in these applications under appropriate conditions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 254.21
    methanol 378.23
    isopropanol 242.93
    water 0.57
    ethyl acetate 329.67
    n-propanol 206.17
    acetone 606.35
    n-butanol 208.19
    acetonitrile 424.01
    DMF 778.06
    toluene 184.02
    isobutanol 181.3
    1,4-dioxane 502.89
    methyl acetate 359.93
    THF 676.9
    2-butanone 434.55
    n-pentanol 223.36
    sec-butanol 225.89
    n-hexane 39.51
    ethylene glycol 38.08
    NMP 697.9
    cyclohexane 69.38
    DMSO 853.94
    n-butyl acetate 296.63
    n-octanol 130.22
    chloroform 1637.2
    n-propyl acetate 308.29
    acetic acid 539.4
    dichloromethane 1513.37
    cyclohexanone 696.33
    propylene glycol 64.24
    isopropyl acetate 239.5
    DMAc 857.99
    2-ethoxyethanol 315.01
    isopentanol 202.58
    n-heptane 16.66
    ethyl formate 322.32
    1,2-dichloroethane 822.12
    n-hexanol 165.0
    2-methoxyethanol 386.18
    isobutyl acetate 195.61
    tetrachloromethane 184.74
    n-pentyl acetate 255.87
    transcutol 554.35
    n-heptanol 97.01
    ethylbenzene 148.89
    MIBK 217.18
    2-propoxyethanol 258.22
    tert-butanol 316.22
    MTBE 290.2
    2-butoxyethanol 198.3
    propionic acid 262.17
    o-xylene 145.88
    formic acid 141.72
    diethyl ether 226.55
    m-xylene 114.8
    p-xylene 237.9
    chlorobenzene 428.77
    dimethyl carbonate 122.46
    n-octane 15.92
    formamide 192.89
    cyclopentanone 699.87
    2-pentanone 320.37
    anisole 278.65
    cyclopentyl methyl ether 259.67
    gamma-butyrolactone 790.15
    1-methoxy-2-propanol 279.77
    pyridine 614.16
    3-pentanone 271.95
    furfural 784.0
    n-dodecane 15.68
    diethylene glycol 171.39
    diisopropyl ether 74.41
    tert-amyl alcohol 302.75
    acetylacetone 444.09
    n-hexadecane 17.96
    acetophenone 334.32
    methyl propionate 252.93
    isopentyl acetate 262.18
    trichloroethylene 1548.23
    n-nonanol 112.3
    cyclohexanol 253.95
    benzyl alcohol 259.13
    2-ethylhexanol 111.85
    isooctanol 87.91
    dipropyl ether 122.34
    1,2-dichlorobenzene 433.68
    ethyl lactate 144.04
    propylene carbonate 486.24
    n-methylformamide 354.67
    2-pentanol 142.42
    n-pentane 24.69
    1-propoxy-2-propanol 187.68
    1-methoxy-2-propyl acetate 227.24
    2-(2-methoxypropoxy) propanol 191.97
    mesitylene 82.72
    ε-caprolactone 555.38
    p-cymene 79.66
    epichlorohydrin 802.56
    1,1,1-trichloroethane 746.42
    2-aminoethanol 94.24
    morpholine-4-carbaldehyde 593.18
    sulfolane 872.74
    2,2,4-trimethylpentane 23.5
    2-methyltetrahydrofuran 465.3
    n-hexyl acetate 318.55
    isooctane 12.88
    2-(2-butoxyethoxy)ethanol 241.96
    sec-butyl acetate 200.29
    tert-butyl acetate 259.89
    decalin 44.1
    glycerin 100.96
    diglyme 529.54
    acrylic acid 251.86
    isopropyl myristate 113.95
    n-butyric acid 394.5
    acetyl acetate 299.82
    di(2-ethylhexyl) phthalate 124.88
    ethyl propionate 257.92
    nitromethane 827.04
    1,2-diethoxyethane 272.39
    benzonitrile 408.35
    trioctyl phosphate 91.74
    1-bromopropane 427.05
    gamma-valerolactone 804.35
    n-decanol 78.82
    triethyl phosphate 132.39
    4-methyl-2-pentanol 94.65
    propionitrile 320.18
    vinylene carbonate 485.06
    1,1,2-trichlorotrifluoroethane 579.05
    DMS 213.09
    cumene 100.66
    2-octanol 92.73
    2-hexanone 343.46
    octyl acetate 150.05
    limonene 113.35
    1,2-dimethoxyethane 643.31
    ethyl orthosilicate 123.2
    tributyl phosphate 124.79
    diacetone alcohol 264.88
    N,N-dimethylaniline 200.22
    acrylonitrile 417.51
    aniline 206.57
    1,3-propanediol 183.74
    bromobenzene 474.48
    dibromomethane 957.73
    1,1,2,2-tetrachloroethane 1212.37
    2-methyl-cyclohexyl acetate 184.2
    tetrabutyl urea 162.6
    diisobutyl methanol 72.54
    2-phenylethanol 181.43
    styrene 202.6
    dioctyl adipate 187.36
    dimethyl sulfate 235.45
    ethyl butyrate 219.62
    methyl lactate 135.3
    butyl lactate 188.42
    diethyl carbonate 166.07
    propanediol butyl ether 187.92
    triethyl orthoformate 155.55
    p-tert-butyltoluene 73.5
    methyl 4-tert-butylbenzoate 240.87
    morpholine 551.81
    tert-butylamine 180.44
    n-dodecanol 60.7
    dimethoxymethane 320.24
    ethylene carbonate 391.6
    cyrene 241.2
    2-ethoxyethyl acetate 276.23
    2-ethylhexyl acetate 204.48
    1,2,4-trichlorobenzene 453.73
    4-methylpyridine 623.2
    dibutyl ether 178.79
    2,6-dimethyl-4-heptanol 72.54
    DEF 412.06
    dimethyl isosorbide 317.69
    tetrachloroethylene 767.83
    eugenol 234.59
    triacetin 283.56
    span 80 190.84
    1,4-butanediol 105.38
    1,1-dichloroethane 773.4
    2-methyl-1-pentanol 212.49
    methyl formate 303.38
    2-methyl-1-butanol 190.59
    n-decane 26.2
    butyronitrile 362.77
    3,7-dimethyl-1-octanol 120.08
    1-chlorooctane 110.22
    1-chlorotetradecane 45.05
    n-nonane 25.33
    undecane 19.18
    tert-butylcyclohexane 35.72
    cyclooctane 19.61
    cyclopentanol 267.04
    tetrahydropyran 470.3
    tert-amyl methyl ether 219.6
    2,5,8-trioxanonane 329.79
    1-hexene 158.28
    2-isopropoxyethanol 224.05
    2,2,2-trifluoroethanol 184.24
    methyl butyrate 391.79

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction