Dipotassium 5'-inosinate

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  • Identifiers

    CAS number
    20262-26-4

    Molecular formula
    C10H11K2N4O8P

    SMILES
    C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])[O-])O)O.[K+].[K+]

  • Odor profile

    Fragrance
    Odorless 89.78%
    Savory 17.42%
    Bitter 17.2%
    Milky 15.07%
    Sweet 14.36%
    Cooked 14.28%
    Cooling 13.73%
    Clean 13.21%
    Alcoholic 10.62%
    Burnt 9.64%

     

    Flavor
    Bitter 62.6%
    Odorless 57.42%
    Bland 31.96%
    Very mild 25.99%
    Sweet-like 23.65%
    Mild 22.95%
    Yeast 19.61%
    Nitrile 18.98%
    Bread crust 18.67%
    Scallion 18.45%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    4.82 (weak acid)

    Molecular weight
    424.39 g/mol

    Flash point

    • 365.15 ˚C est.

    Solubility expt.

    • Freely soluble in water; practically insoluble in ethanol

  • Synonyms

    • Dipotassium 5'-inosinate
    • UNII-3BYM6LW3RF
    • 3BYM6LW3RF
    • potassium inosinate
    • dipotassium inosinate
    • 20262-26-4
    • EINECS 243-652-3
    • POTASSIUM 5'-INOSINATE
    • INS NO.632
    • INS NO. 632
    • INS-632
    • DIPOTASSIUM INOSINE-5'-MONOPHOSPHATE
    • E-632
    • 5'-Inosinic acid, dipotassium salt
    • SCHEMBL247204
    • 5'-Inosinic acid,dipotassium salt
    • potassium inosine-5'-monophosphate
    • E632
    • Potassium inosinatePotassium 5'-inosinate
    • 5'-INOSINIC ACID, POTASSIUM SALT (1:2)
    • Q27257017
    • 243-652-3

  • Applications

    Dipotassium 5'-inosinate (CAS 20262-26-4) is primarily used in the food industry as an umami flavor enhancer, commonly incorporated into processed foods, soups, sauces, and snacks to boost savory notes and to complement other taste additives such as MSG. It can also function as a nucleotide intermediate or building block in laboratory-scale synthesis for biochemical research and pharmaceutical development. In certain markets, it is considered for specialty nutritional formulations or functional foods as a nucleotide source, with use governed by local regulations and formulation limits. Its applications are therefore centered on food flavor enhancement with secondary roles in research and niche product development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.68
    methanol 1.86
    isopropanol 0.66
    water 11.23
    ethyl acetate 0.12
    n-propanol 0.79
    acetone 0.33
    n-butanol 0.57
    acetonitrile 0.35
    DMF 20.73
    toluene 0.03
    isobutanol 0.39
    1,4-dioxane 0.6
    methyl acetate 0.3
    THF 0.96
    2-butanone 0.53
    n-pentanol 0.26
    sec-butanol 0.68
    n-hexane 0.02
    ethylene glycol 8.13
    NMP 39.25
    cyclohexane 0.05
    DMSO 24.69
    n-butyl acetate 0.26
    n-octanol 0.31
    chloroform 0.04
    n-propyl acetate 0.13
    acetic acid 3.1
    dichloromethane 0.06
    cyclohexanone 0.97
    propylene glycol 6.49
    isopropyl acetate 0.08
    DMAc 22.64
    2-ethoxyethanol 3.62
    isopentanol 0.33
    n-heptane 0.06
    ethyl formate 0.43
    1,2-dichloroethane 0.07
    n-hexanol 0.35
    2-methoxyethanol 11.95
    isobutyl acetate 0.04
    tetrachloromethane 0.03
    n-pentyl acetate 0.26
    transcutol 3.44
    n-heptanol 0.53
    ethylbenzene 0.02
    MIBK 0.12
    2-propoxyethanol 3.21
    tert-butanol 0.48
    MTBE 0.09
    2-butoxyethanol 2.59
    propionic acid 1.53
    o-xylene 0.05
    formic acid 32.52
    diethyl ether 0.16
    m-xylene 0.03
    p-xylene 0.04
    chlorobenzene 0.01
    dimethyl carbonate 0.71
    n-octane 0.03
    formamide 37.48
    cyclopentanone 1.6
    2-pentanone 0.28
    anisole 0.07
    cyclopentyl methyl ether 0.37
    gamma-butyrolactone 2.18
    1-methoxy-2-propanol 5.73
    pyridine 0.59
    3-pentanone 0.37
    furfural 3.12
    n-dodecane 0.02
    diethylene glycol 9.18
    diisopropyl ether 0.04
    tert-amyl alcohol 0.55
    acetylacetone 0.28
    n-hexadecane 0.02
    acetophenone 0.2
    methyl propionate 0.43
    isopentyl acetate 0.18
    trichloroethylene 0.08
    n-nonanol 0.33
    cyclohexanol 0.57
    benzyl alcohol 0.21
    2-ethylhexanol 0.19
    isooctanol 0.27
    dipropyl ether 0.35
    1,2-dichlorobenzene 0.02
    ethyl lactate 0.95
    propylene carbonate 0.63
    n-methylformamide 8.52
    2-pentanol 0.33
    n-pentane 0.02
    1-propoxy-2-propanol 2.12
    1-methoxy-2-propyl acetate 0.49
    2-(2-methoxypropoxy) propanol 1.86
    mesitylene 0.02
    ε-caprolactone 0.94
    p-cymene 0.06
    epichlorohydrin 0.57
    1,1,1-trichloroethane 0.02
    2-aminoethanol 6.46
    morpholine-4-carbaldehyde 13.93
    sulfolane 10.29
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.46
    n-hexyl acetate 0.22
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 2.61
    sec-butyl acetate 0.06
    tert-butyl acetate 0.1
    decalin 0.01
    glycerin 29.19
    diglyme 4.18
    acrylic acid 2.85
    isopropyl myristate 0.1
    n-butyric acid 0.75
    acetyl acetate 0.07
    di(2-ethylhexyl) phthalate 0.2
    ethyl propionate 0.16
    nitromethane 4.93
    1,2-diethoxyethane 0.36
    benzonitrile 0.15
    trioctyl phosphate 0.22
    1-bromopropane 0.05
    gamma-valerolactone 4.88
    n-decanol 0.25
    triethyl phosphate 0.32
    4-methyl-2-pentanol 0.11
    propionitrile 0.3
    vinylene carbonate 0.53
    1,1,2-trichlorotrifluoroethane 4.11
    DMS 0.24
    cumene 0.02
    2-octanol 0.3
    2-hexanone 0.17
    octyl acetate 0.18
    limonene 0.09
    1,2-dimethoxyethane 2.26
    ethyl orthosilicate 0.26
    tributyl phosphate 0.19
    diacetone alcohol 0.91
    N,N-dimethylaniline 0.11
    acrylonitrile 0.59
    aniline 0.18
    1,3-propanediol 5.1
    bromobenzene 0.01
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.12
    2-methyl-cyclohexyl acetate 0.19
    tetrabutyl urea 0.64
    diisobutyl methanol 0.11
    2-phenylethanol 0.26
    styrene 0.02
    dioctyl adipate 0.18
    dimethyl sulfate 2.38
    ethyl butyrate 0.26
    methyl lactate 3.34
    butyl lactate 1.02
    diethyl carbonate 0.21
    propanediol butyl ether 2.9
    triethyl orthoformate 0.38
    p-tert-butyltoluene 0.05
    methyl 4-tert-butylbenzoate 0.54
    morpholine 1.55
    tert-butylamine 0.15
    n-dodecanol 0.17
    dimethoxymethane 2.46
    ethylene carbonate 0.4
    cyrene 3.51
    2-ethoxyethyl acetate 0.4
    2-ethylhexyl acetate 0.14
    1,2,4-trichlorobenzene 0.05
    4-methylpyridine 0.26
    dibutyl ether 0.16
    2,6-dimethyl-4-heptanol 0.11
    DEF 1.6
    dimethyl isosorbide 2.03
    tetrachloroethylene 0.11
    eugenol 0.96
    triacetin 0.38
    span 80 1.33
    1,4-butanediol 1.99
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.16
    methyl formate 3.49
    2-methyl-1-butanol 0.43
    n-decane 0.04
    butyronitrile 0.19
    3,7-dimethyl-1-octanol 0.14
    1-chlorooctane 0.05
    1-chlorotetradecane 0.03
    n-nonane 0.03
    undecane 0.02
    tert-butylcyclohexane 0.0
    cyclooctane 0.02
    cyclopentanol 1.06
    tetrahydropyran 0.35
    tert-amyl methyl ether 0.16
    2,5,8-trioxanonane 3.24
    1-hexene 0.03
    2-isopropoxyethanol 1.09
    2,2,2-trifluoroethanol 3.69
    methyl butyrate 0.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction