Diphenyl disulfide

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  • Identifiers

    CAS number
    882-33-7

    Molecular formula
    C12H10S2

    SMILES
    C1=CC=C(C=C1)SSC2=CC=CC=C2

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Sulfurous 84.59%
    Meaty 67.85%
    Burnt 65.28%
    Earthy 57.93%
    Roasted 53.81%
    Mushroom 52.46%
    Coffee 51.6%
    Garlic 50.82%
    Alliaceous 43.73%
    Pungent 43.07%

     

    Flavor
    Sulfurous 38.61%
    Meaty 37.0%
    Onion 36.91%
    Green 36.06%
    Garlic 35.37%
    Metallic 33.62%
    Pungent 33.18%
    Horseradish 31.86%
    Alliaceous 31.5%
    Sulfury 30.08%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.4

    pKa est.
    5.42 (weak acid)

    Molecular weight
    218.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 62 - 63 °C

    Boiling point

    • 310.00 °C. @ 760.00 mm Hg

    Flash point

    • 164.66 ˚C est.

    Solubility expt.

    • insoluble in water; soluble in alcohol, ether, carbon disulfide

  • Synonyms

    • DIPHENYL DISULFIDE
    • Phenyl disulfide
    • 882-33-7
    • 1,2-diphenyldisulfane
    • (Phenyldisulfanyl)benzene
    • Disulfide, diphenyl
    • Diphenyl disulphide
    • diphenyldisulfide
    • Biphenyl disulfide
    • Phenyldithiobenzene
    • Disulfide diphenyl
    • USAF E-1
    • FEMA No. 3225
    • 1,1'-dithiodibenzene
    • Phenyldisulfide
    • diphenyldisulphide
    • NSC 2689
    • EINECS 212-926-4
    • MFCD00003065
    • DTXSID6022131
    • AI3-02911
    • 7P54H519IJ
    • NSC-2689
    • MLS000069663
    • CHEMBL462861
    • DTXCID702131
    • DIPHENYL DISULFIDE [MI]
    • DIPHENYL DISULFIDE [FHFI]
    • NSC2689
    • SMR000059177
    • 1,1'-disulfanediyldibenzene
    • phenyidisulfide
    • phenyldisulphide
    • Dithiobisbenzene
    • UNII-7P54H519IJ
    • diphenyidisulfide
    • phenyl-disulfide
    • phenyl disulphide
    • PhSSPh
    • bis-(phenyl)disulfide
    • phenyldisulfanyl-benzene
    • (phenyldisulanyl)benzene
    • Phenyl disulfide, 8CI
    • Ph-S-S-Ph
    • Opera_ID_773
    • Phenyl disulfide, 99%
    • WLN: RSSR
    • (Phenyldisulfanyl)benzene #
    • SCHEMBL5148
    • Phenyl disulfide, >=98%
    • FEMA 3225
    • CHEBI:174102
    • HMS2235I05
    • HY-Y1177
    • STR01628
    • Tox21_200728
    • BDBM50450778
    • NSC799311
    • Phenyl disulfide, analytical standard
    • STL182756
    • AKOS000120953
    • FD40111
    • NSC-799311
    • NCGC00093353-02
    • NCGC00258282-01
    • CAS-882-33-7
    • DB-011816
    • CS-0017165
    • NS00022864
    • P0167
    • EN300-20703
    • D72521
    • A842506
    • Diphenyl disulfide, technical, >=97.0% (HPLC)
    • Q2423101
    • F0001-2477
    • Z104480056
    • ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (DIPHENYL DISULPHIDE)
    • 212-926-4
    • 93345-44-9

  • Applications

    Diphenyl disulfide is primarily used as an organic sulfur-containing building block in chemical synthesis, serving as a precursor to aryl sulfides and other sulfur-containing compounds via disulfide exchange or reduction. In polymer and rubber formulations, it can act as a sulfur-donor crosslinking agent and as a processing stabilizer, helping to control cure chemistry and minimize radical-initiated degradation during processing. It is also employed as a reagent to introduce disulfide functionality in research and development and to modify coatings and inks through sulfur-containing linkages. Additionally, it serves as a starting material for preparing other organosulfur compounds in specialized applications, subject to appropriate regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.1
    methanol 5.25
    isopropanol 8.57
    water 0.0
    ethyl acetate 269.88
    n-propanol 11.59
    acetone 367.24
    n-butanol 12.14
    acetonitrile 93.85
    DMF 598.99
    toluene 327.38
    isobutanol 9.92
    1,4-dioxane 725.86
    methyl acetate 268.88
    THF 1252.34
    2-butanone 302.01
    n-pentanol 14.29
    sec-butanol 12.62
    n-hexane 8.05
    ethylene glycol 2.32
    NMP 809.01
    cyclohexane 41.58
    DMSO 371.15
    n-butyl acetate 231.98
    n-octanol 19.15
    chloroform 696.81
    n-propyl acetate 167.64
    acetic acid 44.45
    dichloromethane 820.77
    cyclohexanone 750.85
    propylene glycol 6.08
    isopropyl acetate 181.93
    DMAc 590.84
    2-ethoxyethanol 47.56
    isopentanol 15.38
    n-heptane 20.3
    ethyl formate 117.87
    1,2-dichloroethane 642.21
    n-hexanol 22.33
    2-methoxyethanol 68.59
    isobutyl acetate 116.73
    tetrachloromethane 57.68
    n-pentyl acetate 120.17
    transcutol 434.07
    n-heptanol 13.78
    ethylbenzene 133.29
    MIBK 151.08
    2-propoxyethanol 63.37
    tert-butanol 20.9
    MTBE 90.38
    2-butoxyethanol 40.17
    propionic acid 38.47
    o-xylene 145.25
    formic acid 4.68
    diethyl ether 113.54
    m-xylene 137.49
    p-xylene 143.6
    chlorobenzene 404.6
    dimethyl carbonate 166.0
    n-octane 8.87
    formamide 25.49
    cyclopentanone 1257.5
    2-pentanone 251.44
    anisole 382.35
    cyclopentyl methyl ether 405.48
    gamma-butyrolactone 1033.08
    1-methoxy-2-propanol 58.7
    pyridine 859.91
    3-pentanone 270.05
    furfural 888.7
    n-dodecane 7.23
    diethylene glycol 31.03
    diisopropyl ether 53.6
    tert-amyl alcohol 23.06
    acetylacetone 591.88
    n-hexadecane 9.24
    acetophenone 351.08
    methyl propionate 234.73
    isopentyl acetate 206.64
    trichloroethylene 1684.85
    n-nonanol 22.28
    cyclohexanol 41.6
    benzyl alcohol 97.23
    2-ethylhexanol 38.4
    isooctanol 15.9
    dipropyl ether 148.54
    1,2-dichlorobenzene 382.27
    ethyl lactate 50.42
    propylene carbonate 460.88
    n-methylformamide 92.55
    2-pentanol 12.8
    n-pentane 4.7
    1-propoxy-2-propanol 72.1
    1-methoxy-2-propyl acetate 312.14
    2-(2-methoxypropoxy) propanol 108.06
    mesitylene 86.86
    ε-caprolactone 499.66
    p-cymene 80.99
    epichlorohydrin 1084.61
    1,1,1-trichloroethane 477.09
    2-aminoethanol 5.96
    morpholine-4-carbaldehyde 788.26
    sulfolane 1162.32
    2,2,4-trimethylpentane 6.59
    2-methyltetrahydrofuran 511.47
    n-hexyl acetate 149.12
    isooctane 5.28
    2-(2-butoxyethoxy)ethanol 116.22
    sec-butyl acetate 131.37
    tert-butyl acetate 246.68
    decalin 30.97
    glycerin 12.84
    diglyme 417.21
    acrylic acid 46.81
    isopropyl myristate 84.86
    n-butyric acid 63.94
    acetyl acetate 281.24
    di(2-ethylhexyl) phthalate 70.93
    ethyl propionate 177.32
    nitromethane 313.79
    1,2-diethoxyethane 316.66
    benzonitrile 241.48
    trioctyl phosphate 36.83
    1-bromopropane 176.09
    gamma-valerolactone 1224.9
    n-decanol 18.37
    triethyl phosphate 117.79
    4-methyl-2-pentanol 13.28
    propionitrile 68.29
    vinylene carbonate 428.64
    1,1,2-trichlorotrifluoroethane 369.29
    DMS 302.9
    cumene 68.57
    2-octanol 12.9
    2-hexanone 178.19
    octyl acetate 86.21
    limonene 130.08
    1,2-dimethoxyethane 330.84
    ethyl orthosilicate 102.29
    tributyl phosphate 59.83
    diacetone alcohol 147.0
    N,N-dimethylaniline 191.46
    acrylonitrile 131.76
    aniline 160.03
    1,3-propanediol 11.83
    bromobenzene 592.35
    dibromomethane 439.06
    1,1,2,2-tetrachloroethane 931.61
    2-methyl-cyclohexyl acetate 180.88
    tetrabutyl urea 103.86
    diisobutyl methanol 36.3
    2-phenylethanol 98.51
    styrene 215.66
    dioctyl adipate 150.42
    dimethyl sulfate 361.59
    ethyl butyrate 229.28
    methyl lactate 66.71
    butyl lactate 62.55
    diethyl carbonate 165.64
    propanediol butyl ether 37.02
    triethyl orthoformate 164.41
    p-tert-butyltoluene 80.92
    methyl 4-tert-butylbenzoate 193.17
    morpholine 465.92
    tert-butylamine 13.15
    n-dodecanol 16.67
    dimethoxymethane 323.51
    ethylene carbonate 291.77
    cyrene 176.63
    2-ethoxyethyl acetate 254.98
    2-ethylhexyl acetate 197.04
    1,2,4-trichlorobenzene 502.23
    4-methylpyridine 586.59
    dibutyl ether 126.23
    2,6-dimethyl-4-heptanol 36.3
    DEF 328.48
    dimethyl isosorbide 448.38
    tetrachloroethylene 443.34
    eugenol 132.07
    triacetin 249.17
    span 80 89.56
    1,4-butanediol 5.74
    1,1-dichloroethane 326.08
    2-methyl-1-pentanol 20.16
    methyl formate 130.77
    2-methyl-1-butanol 14.36
    n-decane 11.83
    butyronitrile 67.42
    3,7-dimethyl-1-octanol 35.79
    1-chlorooctane 55.57
    1-chlorotetradecane 26.05
    n-nonane 10.68
    undecane 8.82
    tert-butylcyclohexane 21.49
    cyclooctane 18.7
    cyclopentanol 60.14
    tetrahydropyran 444.55
    tert-amyl methyl ether 97.47
    2,5,8-trioxanonane 287.21
    1-hexene 33.87
    2-isopropoxyethanol 43.33
    2,2,2-trifluoroethanol 20.68
    methyl butyrate 228.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction