Dipalmitoylethyl hydroxyethylmonium methosulfate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    161294-46-8

    Molecular formula
    C40H81NO9S

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCC[N+](C)(CCO)CCOC(=O)CCCCCCCCCCCCCCC.COS(=O)(=O)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Waxy 61.64%
    Fatty 52.5%
    Oily 48.67%
    Odorless 37.19%
    Sweet 28.39%
    Creamy 24.65%
    Fruity 22.85%
    Alcoholic 21.13%
    Floral 21.0%
    Clean 20.43%

     

    Flavor
    Waxy 46.58%
    Mild 43.11%
    Fatty 39.95%
    Oily 39.25%
    Bland 37.44%
    Faint 29.86%
    Odorless 27.85%
    Soapy 25.3%
    Fat 24.81%
    Slightly waxy 24.39%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.22 (weak base)

    Molecular weight
    752.1 g/mol

    Flash point

    • 54.69 ˚C est.

  • Synonyms

    • Dipalmitoylethyl hydroxyethylmonium methosulfate
    • UNII-X241W7C3L7
    • X241W7C3L7
    • 161294-46-8
    • (Hydroxyethyl)methylbis(palmitoyloxyethyl)ammonium methyl sulfate
    • Ethanaminium, N-(2-hydroxyethyl)-N-methyl-2-((1-oxohexadecyl)oxy)-N-(2-((1-oxohexadecyl)oxy)ethyl)-, methyl sulfate (1:1)
    • Ethanaminium, N-(2-hydroxyethyl)-N-methyl-2-((1-oxohexadecyl)oxy)-N-(2-((1-oxohexadecyl)oxy)ethyl)-, methyl sulfate (Salt)
    • DTXSID60167103
    • RefChem:134596
    • DTXCID7089594
    • DIPALMITOYLETHYL HYDROXYETHYLMONIUM METHOSULFATE [INCI]
    • SCHEMBL81271
    • WQMJXFAFCDSZKC-UHFFFAOYSA-M
    • NS00114373
    • Q27293381
    • 2-(Hexadecanoyloxy)-N-[2-(hexadecanoyloxy)ethyl]-N-(2-hydroxyethyl)-N-methylethan-1-aminium methyl sulfate
    • 161294-46-8

  • Applications

    Chemical name: Dipalmitoylethyl hydroxyethylmonium methosulfate; CAS number: 161294-46-8. Dipalmitoylethyl hydroxyethylmonium methosulfate is a cationic surfactant with two long palmitoyl chains, commonly used as a conditioning surfactant and emulsifier in cosmetics and personal-care formulations such as shampoos, conditioners, and cleansers. Its quaternary ammonium nature supports improved wetting, dispersion, and texture in emulsions and creams, and it is often evaluated as an additive in cosmetic formulations for stabilization. The compound can also be employed in household cleaning products as a surfactant to enhance cleaning performance. In industrial contexts, it may function as a surfactant or emulsifier additive in coatings, inks, and polymer processing to improve wetting, dispersion, and formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.4
    methanol 22.32
    isopropanol 7.47
    water 1.36
    ethyl acetate 57.85
    n-propanol 14.2
    acetone 47.65
    n-butanol 11.47
    acetonitrile 18.15
    DMF 82.16
    toluene 30.94
    isobutanol 11.68
    1,4-dioxane 61.98
    methyl acetate 45.24
    THF 140.74
    2-butanone 54.47
    n-pentanol 11.7
    sec-butanol 12.92
    n-hexane 3.64
    ethylene glycol 3.48
    NMP 386.76
    cyclohexane 12.35
    DMSO 110.75
    n-butyl acetate 37.97
    n-octanol 16.62
    chloroform 209.88
    n-propyl acetate 50.77
    acetic acid 78.99
    dichloromethane 205.51
    cyclohexanone 164.42
    propylene glycol 6.21
    isopropyl acetate 44.01
    DMAc 227.7
    2-ethoxyethanol 37.37
    isopentanol 10.85
    n-heptane 3.72
    ethyl formate 35.6
    1,2-dichloroethane 100.8
    n-hexanol 9.25
    2-methoxyethanol 41.0
    isobutyl acetate 31.29
    tetrachloromethane 48.15
    n-pentyl acetate 87.24
    transcutol 178.75
    n-heptanol 16.54
    ethylbenzene 19.16
    MIBK 29.26
    2-propoxyethanol 33.17
    tert-butanol 11.41
    MTBE 21.06
    2-butoxyethanol 55.7
    propionic acid 45.31
    o-xylene 31.35
    formic acid 36.43
    diethyl ether 18.82
    m-xylene 22.81
    p-xylene 27.96
    chlorobenzene 53.76
    dimethyl carbonate 39.9
    n-octane 2.49
    formamide 52.02
    cyclopentanone 184.0
    2-pentanone 42.47
    anisole 32.09
    cyclopentyl methyl ether 84.09
    gamma-butyrolactone 247.0
    1-methoxy-2-propanol 34.39
    pyridine 88.05
    3-pentanone 54.33
    furfural 194.62
    n-dodecane 1.46
    diethylene glycol 18.15
    diisopropyl ether 9.6
    tert-amyl alcohol 18.51
    acetylacetone 85.15
    n-hexadecane 1.71
    acetophenone 63.57
    methyl propionate 59.24
    isopentyl acetate 36.71
    trichloroethylene 240.86
    n-nonanol 18.01
    cyclohexanol 32.34
    benzyl alcohol 26.79
    2-ethylhexanol 11.04
    isooctanol 16.48
    dipropyl ether 22.26
    1,2-dichlorobenzene 73.5
    ethyl lactate 30.79
    propylene carbonate 134.17
    n-methylformamide 45.0
    2-pentanol 9.0
    n-pentane 2.67
    1-propoxy-2-propanol 33.46
    1-methoxy-2-propyl acetate 57.0
    2-(2-methoxypropoxy) propanol 49.59
    mesitylene 15.82
    ε-caprolactone 181.83
    p-cymene 14.01
    epichlorohydrin 170.98
    1,1,1-trichloroethane 119.93
    2-aminoethanol 10.41
    morpholine-4-carbaldehyde 176.28
    sulfolane 437.67
    2,2,4-trimethylpentane 3.5
    2-methyltetrahydrofuran 95.41
    n-hexyl acetate 69.95
    isooctane 1.27
    2-(2-butoxyethoxy)ethanol 61.88
    sec-butyl acetate 40.64
    tert-butyl acetate 57.63
    decalin 6.81
    glycerin 14.92
    diglyme 152.45
    acrylic acid 47.7
    isopropyl myristate 19.74
    n-butyric acid 61.33
    acetyl acetate 59.76
    di(2-ethylhexyl) phthalate 27.78
    ethyl propionate 49.5
    nitromethane 141.48
    1,2-diethoxyethane 55.47
    benzonitrile 32.76
    trioctyl phosphate 18.76
    1-bromopropane 38.16
    gamma-valerolactone 280.34
    n-decanol 10.84
    triethyl phosphate 39.86
    4-methyl-2-pentanol 6.87
    propionitrile 17.4
    vinylene carbonate 128.98
    1,1,2-trichlorotrifluoroethane 180.94
    DMS 62.23
    cumene 13.77
    2-octanol 13.99
    2-hexanone 40.87
    octyl acetate 30.06
    limonene 20.59
    1,2-dimethoxyethane 63.86
    ethyl orthosilicate 36.78
    tributyl phosphate 25.47
    diacetone alcohol 51.33
    N,N-dimethylaniline 30.58
    acrylonitrile 25.79
    aniline 32.48
    1,3-propanediol 13.1
    bromobenzene 61.29
    dibromomethane 106.39
    1,1,2,2-tetrachloroethane 206.27
    2-methyl-cyclohexyl acetate 47.58
    tetrabutyl urea 37.54
    diisobutyl methanol 7.44
    2-phenylethanol 21.03
    styrene 20.54
    dioctyl adipate 44.18
    dimethyl sulfate 108.07
    ethyl butyrate 45.9
    methyl lactate 37.95
    butyl lactate 65.89
    diethyl carbonate 32.11
    propanediol butyl ether 43.23
    triethyl orthoformate 47.47
    p-tert-butyltoluene 13.76
    methyl 4-tert-butylbenzoate 86.25
    morpholine 78.41
    tert-butylamine 7.78
    n-dodecanol 7.03
    dimethoxymethane 52.69
    ethylene carbonate 102.04
    cyrene 77.89
    2-ethoxyethyl acetate 117.45
    2-ethylhexyl acetate 35.22
    1,2,4-trichlorobenzene 100.29
    4-methylpyridine 71.96
    dibutyl ether 25.36
    2,6-dimethyl-4-heptanol 7.44
    DEF 76.52
    dimethyl isosorbide 122.55
    tetrachloroethylene 159.6
    eugenol 65.03
    triacetin 126.01
    span 80 49.91
    1,4-butanediol 7.37
    1,1-dichloroethane 71.25
    2-methyl-1-pentanol 13.5
    methyl formate 40.9
    2-methyl-1-butanol 14.23
    n-decane 3.38
    butyronitrile 15.38
    3,7-dimethyl-1-octanol 14.64
    1-chlorooctane 16.4
    1-chlorotetradecane 5.01
    n-nonane 3.05
    undecane 2.07
    tert-butylcyclohexane 4.53
    cyclooctane 5.12
    cyclopentanol 36.67
    tetrahydropyran 69.6
    tert-amyl methyl ether 29.2
    2,5,8-trioxanonane 87.96
    1-hexene 9.11
    2-isopropoxyethanol 29.02
    2,2,2-trifluoroethanol 56.57
    methyl butyrate 63.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction