Dipalmitoyl Cystine

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  • Identifiers

    CAS number
    17627-10-0

    Molecular formula
    C38H72N2O6S2

    SMILES
    CCCCCCCCCCCCCCCC(=O)N[C@@H](CSSC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCC)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Savory 39.47%
    Odorless 37.73%
    Meaty 36.77%
    Fatty 34.46%
    Waxy 32.88%
    Oily 24.97%
    Cooling 22.32%
    Fishy 20.24%
    Milky 20.16%
    Cooked 18.89%

     

    Flavor
    Bland 42.42%
    Odorless 39.8%
    Mild 30.66%
    Faint 25.42%
    Slightly waxy 21.09%
    Bitter 20.1%
    Bay oil 20.0%
    Delicate 19.57%
    Cedarleaf 19.29%
    Sweet-like 19.16%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    13.5

    pKa est.
    8.75 (weak base)

    Molecular weight
    717.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    882°C

    Flash point

    • 329.15 ˚C est.

  • Synonyms

    • dipalmitoyl cystine
    • 17627-10-0
    • L-Cystine, N,N'-bis(1-oxohexadecyl)-
    • N,N'-Dipalmitoyl-L-cystine
    • Palmitoyl cystine
    • S7NI60Y64I
    • EINECS 241-607-2
    • DTXSID10884979
    • CYSTINE, N,N'-DIPALMITOYL-, L-
    • RefChem:588777
    • DIPALMITOYL CYSTINE [INCI]
    • DTXCID001024394
    • 241-607-2
    • (2R)-3-[[(2R)-2-carboxy-2-(hexadecanoylamino)ethyl]disulfanyl]-2-(hexadecanoylamino)propanoic acid
    • UNII-S7NI60Y64I
    • N,N'-Dihexadecanoyl-L-cystine
    • orb1986110
    • SCHEMBL11368104
    • JIUGOZSZLYKDDH-HEVIKAOCSA-N
    • AKOS040751597
    • Q27288784
    • 17627-10-0

  • Applications

    Dipalmitoyl Cystine is a di-palmitoylated derivative of cystine with lipophilic character. In practice, it is typically evaluated as a specialty intermediate and additive across several industries: in cosmetics/personal care as a conditioning/film-forming component and potential emulsion stabilizer; in polymers/plastics as a crosslinking or structure-modifying agent that can influence film formation and mechanical properties; in coatings/inks as a surface-modifying additive to improve compatibility and durability of coatings; in adhesives as a crosslinking/compatibilizing additive; and in industrial manufacturing as an intermediate for synthesis of lipid-bearing specialty chemicals (CAS 17627-10-0).

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.0
    methanol 1.63
    isopropanol 0.76
    water 0.06
    ethyl acetate 2.65
    n-propanol 1.27
    acetone 3.18
    n-butanol 1.06
    acetonitrile 0.76
    DMF 16.96
    toluene 1.44
    isobutanol 0.88
    1,4-dioxane 4.65
    methyl acetate 2.9
    THF 14.86
    2-butanone 4.71
    n-pentanol 1.34
    sec-butanol 1.35
    n-hexane 0.24
    ethylene glycol 0.35
    NMP 58.57
    cyclohexane 0.39
    DMSO 12.44
    n-butyl acetate 2.82
    n-octanol 1.55
    chloroform 7.46
    n-propyl acetate 3.33
    acetic acid 4.63
    dichloromethane 5.87
    cyclohexanone 12.33
    propylene glycol 0.87
    isopropyl acetate 2.48
    DMAc 47.38
    2-ethoxyethanol 4.47
    isopentanol 0.89
    n-heptane 0.19
    ethyl formate 2.4
    1,2-dichloroethane 3.44
    n-hexanol 0.83
    2-methoxyethanol 4.26
    isobutyl acetate 1.94
    tetrachloromethane 1.75
    n-pentyl acetate 5.56
    transcutol 19.49
    n-heptanol 1.36
    ethylbenzene 1.26
    MIBK 2.11
    2-propoxyethanol 3.81
    tert-butanol 0.98
    MTBE 1.72
    2-butoxyethanol 5.61
    propionic acid 3.04
    o-xylene 1.74
    formic acid 2.33
    diethyl ether 1.16
    m-xylene 1.12
    p-xylene 1.76
    chlorobenzene 1.97
    dimethyl carbonate 2.98
    n-octane 0.17
    formamide 3.66
    cyclopentanone 17.05
    2-pentanone 3.33
    anisole 2.72
    cyclopentyl methyl ether 5.48
    gamma-butyrolactone 17.75
    1-methoxy-2-propanol 4.17
    pyridine 5.64
    3-pentanone 3.73
    furfural 15.11
    n-dodecane 0.09
    diethylene glycol 2.08
    diisopropyl ether 0.49
    tert-amyl alcohol 1.91
    acetylacetone 5.68
    n-hexadecane 0.11
    acetophenone 5.53
    methyl propionate 3.74
    isopentyl acetate 2.72
    trichloroethylene 9.4
    n-nonanol 1.62
    cyclohexanol 2.21
    benzyl alcohol 2.5
    2-ethylhexanol 0.83
    isooctanol 1.13
    dipropyl ether 1.52
    1,2-dichlorobenzene 2.89
    ethyl lactate 3.47
    propylene carbonate 9.72
    n-methylformamide 4.93
    2-pentanol 0.84
    n-pentane 0.14
    1-propoxy-2-propanol 3.8
    1-methoxy-2-propyl acetate 4.98
    2-(2-methoxypropoxy) propanol 6.8
    mesitylene 0.76
    ε-caprolactone 13.93
    p-cymene 0.89
    epichlorohydrin 11.12
    1,1,1-trichloroethane 4.47
    2-aminoethanol 0.95
    morpholine-4-carbaldehyde 23.81
    sulfolane 45.49
    2,2,4-trimethylpentane 0.18
    2-methyltetrahydrofuran 7.64
    n-hexyl acetate 5.12
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 7.92
    sec-butyl acetate 2.72
    tert-butyl acetate 3.54
    decalin 0.31
    glycerin 2.0
    diglyme 16.03
    acrylic acid 3.07
    isopropyl myristate 1.39
    n-butyric acid 3.89
    acetyl acetate 2.57
    di(2-ethylhexyl) phthalate 2.24
    ethyl propionate 3.29
    nitromethane 7.98
    1,2-diethoxyethane 4.4
    benzonitrile 2.14
    trioctyl phosphate 1.54
    1-bromopropane 1.7
    gamma-valerolactone 26.88
    n-decanol 0.96
    triethyl phosphate 3.23
    4-methyl-2-pentanol 0.56
    propionitrile 1.0
    vinylene carbonate 7.7
    1,1,2-trichlorotrifluoroethane 15.72
    DMS 4.71
    cumene 1.0
    2-octanol 1.24
    2-hexanone 4.22
    octyl acetate 2.14
    limonene 1.36
    1,2-dimethoxyethane 7.87
    ethyl orthosilicate 3.02
    tributyl phosphate 2.17
    diacetone alcohol 4.89
    N,N-dimethylaniline 3.33
    acrylonitrile 1.43
    aniline 2.07
    1,3-propanediol 1.42
    bromobenzene 1.98
    dibromomethane 3.37
    1,1,2,2-tetrachloroethane 10.71
    2-methyl-cyclohexyl acetate 3.78
    tetrabutyl urea 4.49
    diisobutyl methanol 0.59
    2-phenylethanol 1.93
    styrene 1.29
    dioctyl adipate 3.31
    dimethyl sulfate 10.84
    ethyl butyrate 3.11
    methyl lactate 4.18
    butyl lactate 6.51
    diethyl carbonate 1.99
    propanediol butyl ether 5.65
    triethyl orthoformate 3.73
    p-tert-butyltoluene 0.91
    methyl 4-tert-butylbenzoate 8.43
    morpholine 7.23
    tert-butylamine 0.55
    n-dodecanol 0.59
    dimethoxymethane 5.34
    ethylene carbonate 5.78
    cyrene 10.88
    2-ethoxyethyl acetate 7.88
    2-ethylhexyl acetate 2.45
    1,2,4-trichlorobenzene 4.66
    4-methylpyridine 5.18
    dibutyl ether 1.97
    2,6-dimethyl-4-heptanol 0.59
    DEF 7.93
    dimethyl isosorbide 14.36
    tetrachloroethylene 6.24
    eugenol 6.75
    triacetin 8.92
    span 80 5.52
    1,4-butanediol 0.97
    1,1-dichloroethane 2.92
    2-methyl-1-pentanol 1.41
    methyl formate 3.8
    2-methyl-1-butanol 1.22
    n-decane 0.23
    butyronitrile 1.03
    3,7-dimethyl-1-octanol 1.03
    1-chlorooctane 1.12
    1-chlorotetradecane 0.32
    n-nonane 0.21
    undecane 0.14
    tert-butylcyclohexane 0.24
    cyclooctane 0.17
    cyclopentanol 3.27
    tetrahydropyran 4.51
    tert-amyl methyl ether 2.43
    2,5,8-trioxanonane 10.01
    1-hexene 0.72
    2-isopropoxyethanol 3.23
    2,2,2-trifluoroethanol 3.53
    methyl butyrate 5.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction