Dimethylamine, hydrochloride

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  • Identifiers

    CAS number
    506-59-2

    Molecular formula
    C2H8ClN

    SMILES
    CNC.Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Cheesy 81.8%
    Fishy 79.73%
    Ripe 65.25%
    Fermented 32.61%
    Oily 30.31%
    Pungent 29.96%
    Sweaty 26.78%
    Alcoholic 22.76%
    Odorless 21.99%
    Solvent 21.64%

     

    Flavor
    Fishy 41.94%
    Ammoniacal 28.43%
    Alcoholic 26.42%
    Onion 23.85%
    Pungent 23.12%
    Ammonia 21.5%
    Bitter 21.4%
    Rotten 21.34%
    Decomposing cabbage 21.3%
    Very slight 20.3%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    8.64 (weak base)

    Molecular weight
    81.54 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    6°C

    Flash point

    • -34.82 ˚C est.

  • Synonyms

    • Dimethylamine hydrochloride
    • 506-59-2
    • Dimethylammonium chloride
    • Dimethylamine, hydrochloride
    • Hydrochloric acid dimethylamine
    • 7M4CWB6AOK
    • RefChem:588486
    • 208-046-5
    • N-Methylmethanamine hydrochloride
    • Methanamine, N-methyl-, hydrochloride
    • DIMETHYLAMINE HCl
    • MFCD00012477
    • C2H8ClN
    • Dimethylaminehydrochloride
    • dimethyl amine HCl
    • Metformin Impurity F
    • N,N-dimethylamine hydrochloride
    • N-methylmethanamine;hydrochloride
    • Methanamine, N-methyl-, hydrochloride (1:1)
    • DTXSID8027163
    • DIMETHYLAMINE-15-N HYDROCHLORIDE
    • Dimethyl amine hydrochloride
    • dimethyl ammonium chloride
    • EINECS 208-046-5
    • UNII-7M4CWB6AOK
    • AI3-52357
    • dimethyamine HCl
    • dimethylamine-hcl
    • dimethylamine.HCl
    • dimethyl amine.HCl
    • dimethylammoniumchlorid
    • HNMe2.HCl
    • Me2NH HCl
    • Me2NH-HCl
    • Me2NH.HCl
    • NHMe2.HCl
    • dimethylamine HCl salt
    • dimethylamine-HCl salt
    • dimethylaminium chloride
    • N,N-dimethylamine HCl
    • Dacarbazine Impurity 3
    • dimethyl amine HCl salt
    • dimethlyamine hydrochlorde
    • dimethyamine hydrochloride
    • dimethylamine hydrochoride
    • dimethylamine hyrochloride
    • NH(Me)2.HCl
    • dimethlyamine hydrochloride
    • dimethylamine-hydrochloride
    • Metformin impurity F CRS
    • SCHEMBL733
    • di-methylamine hydrochloride
    • dimethyl-amine hydrochloride
    • dimethylamine hydro chloride
    • dimethylamine hydro-chloride
    • dimethylamine. hydrochloride
    • EC 208-046-5
    • (CH3)2NH HCl
    • (CH3)2NH.HCl
    • N,N-dimethylamine HCl salt
    • dimethylamine monohydrochloride
    • dimethylamine hydrogen chloride
    • dimethylamine hydrochloride salt
    • CHEMBL569461
    • DTXCID907163
    • orb1301902
    • Dimethylamine hydrochloride purum
    • dimethylamine, hydrochloride salt
    • N, N-dimethylamine hydrochloride
    • n,n,-dimethylamine hydrochloride
    • N,N-dimethyl amine hydrochloride
    • N,N-dimethylamine hydro chloride
    • N-methylmethylamine hydrochloride
    • Dimethylamine hydrochloride, 99%
    • N, N-dimethyl amine hydrochloride
    • N-methyl-methanamine hydrochloride
    • HMS5085A10
    • ADA69394
    • dimethylamine hydrochloric acid salt
    • HY-Y1354
    • MSK14284
    • hydrogen chloride N-methylmethanamine
    • Tox21_200696
    • EBC-53058
    • s6197
    • AKOS015900572
    • FD16094
    • DIMETHYLAMINE HYDROCHLORIDE [MI]
    • NCGC00248969-01
    • NCGC00258250-01
    • CAS-506-59-2
    • DB-050357
    • CS-0017816
    • D0644
    • NS00078335
    • N-Methylmethanamine--hydrogen chloride (1/1)
    • F005043
    • Dimethylamine hydrochloride, purum, >=98.0% (AT)
    • Metformin EP Impurity F; Dacarbazine EP Impurity D
    • Q27268559
    • Z1954801776
    • Metformin impurity F, European Pharmacopoeia (EP) Reference Standard
    • Dimethylamine Hydrochloride(Metformin Impurity F), Pharmaceutical Secondary Standard; Certified Reference Material
    • 506-59-2

  • Applications

    Dimethylamine, hydrochloride (CAS 506-59-2) is typically used as a stable, solid source of dimethylamine for organic synthesis. It serves as a building block to introduce dimethylamino groups in pharmaceutical and agrochemical intermediates, and it is also used in the production of dyes and specialty chemicals. In polymer and coating formulations, it provides a means to install tertiary amine functionality; under basic conditions it can release dimethylamine for downstream amination steps. Additionally, it is employed to prepare quaternary ammonium salts and related surfactants or ionic compounds used in various industrial applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 149.46
    methanol 242.78
    isopropanol 63.52
    water 38.7
    ethyl acetate 16.01
    n-propanol 107.23
    acetone 20.95
    n-butanol 72.51
    acetonitrile 24.59
    DMF 53.23
    toluene 2.73
    isobutanol 50.67
    1,4-dioxane 32.3
    methyl acetate 23.54
    THF 54.27
    2-butanone 19.35
    n-pentanol 23.7
    sec-butanol 51.59
    n-hexane 2.62
    ethylene glycol 173.23
    NMP 89.36
    cyclohexane 5.47
    DMSO 56.89
    n-butyl acetate 28.58
    n-octanol 14.83
    chloroform 63.52
    n-propyl acetate 9.94
    acetic acid 356.17
    dichloromethane 41.74
    cyclohexanone 34.09
    propylene glycol 150.51
    isopropyl acetate 5.93
    DMAc 38.53
    2-ethoxyethanol 43.07
    isopentanol 24.92
    n-heptane 9.27
    ethyl formate 27.64
    1,2-dichloroethane 18.28
    n-hexanol 58.94
    2-methoxyethanol 123.83
    isobutyl acetate 5.58
    tetrachloromethane 22.98
    n-pentyl acetate 10.52
    transcutol 58.92
    n-heptanol 25.84
    ethylbenzene 1.45
    MIBK 3.35
    2-propoxyethanol 86.64
    tert-butanol 37.94
    MTBE 7.65
    2-butoxyethanol 48.41
    propionic acid 165.44
    o-xylene 2.63
    formic acid 271.37
    diethyl ether 10.92
    m-xylene 1.79
    p-xylene 2.15
    chlorobenzene 8.83
    dimethyl carbonate 8.74
    n-octane 1.8
    formamide 137.48
    cyclopentanone 50.95
    2-pentanone 10.1
    anisole 5.02
    cyclopentyl methyl ether 18.65
    gamma-butyrolactone 78.32
    1-methoxy-2-propanol 57.92
    pyridine 34.23
    3-pentanone 10.45
    furfural 77.29
    n-dodecane 1.14
    diethylene glycol 100.45
    diisopropyl ether 1.83
    tert-amyl alcohol 34.56
    acetylacetone 8.41
    n-hexadecane 1.13
    acetophenone 7.13
    methyl propionate 19.63
    isopentyl acetate 16.57
    trichloroethylene 41.4
    n-nonanol 12.77
    cyclohexanol 45.35
    benzyl alcohol 13.22
    2-ethylhexanol 26.44
    isooctanol 14.46
    dipropyl ether 19.32
    1,2-dichlorobenzene 9.35
    ethyl lactate 16.48
    propylene carbonate 41.53
    n-methylformamide 78.06
    2-pentanol 24.16
    n-pentane 4.33
    1-propoxy-2-propanol 65.01
    1-methoxy-2-propyl acetate 20.81
    2-(2-methoxypropoxy) propanol 22.97
    mesitylene 1.14
    ε-caprolactone 39.48
    p-cymene 5.09
    epichlorohydrin 37.17
    1,1,1-trichloroethane 16.35
    2-aminoethanol 201.42
    morpholine-4-carbaldehyde 61.98
    sulfolane 96.31
    2,2,4-trimethylpentane 1.72
    2-methyltetrahydrofuran 32.3
    n-hexyl acetate 13.09
    isooctane 0.68
    2-(2-butoxyethoxy)ethanol 33.72
    sec-butyl acetate 4.51
    tert-butyl acetate 5.59
    decalin 1.24
    glycerin 201.32
    diglyme 45.57
    acrylic acid 186.84
    isopropyl myristate 4.62
    n-butyric acid 106.13
    acetyl acetate 11.73
    di(2-ethylhexyl) phthalate 10.13
    ethyl propionate 8.38
    nitromethane 103.11
    1,2-diethoxyethane 12.01
    benzonitrile 12.53
    trioctyl phosphate 7.97
    1-bromopropane 12.01
    gamma-valerolactone 63.08
    n-decanol 9.3
    triethyl phosphate 10.98
    4-methyl-2-pentanol 6.27
    propionitrile 23.82
    vinylene carbonate 41.98
    1,1,2-trichlorotrifluoroethane 115.22
    DMS 11.57
    cumene 1.5
    2-octanol 10.04
    2-hexanone 6.58
    octyl acetate 8.73
    limonene 9.87
    1,2-dimethoxyethane 23.46
    ethyl orthosilicate 10.83
    tributyl phosphate 9.08
    diacetone alcohol 15.32
    N,N-dimethylaniline 4.36
    acrylonitrile 36.01
    aniline 20.02
    1,3-propanediol 150.53
    bromobenzene 5.46
    dibromomethane 28.55
    1,1,2,2-tetrachloroethane 38.1
    2-methyl-cyclohexyl acetate 14.73
    tetrabutyl urea 10.79
    diisobutyl methanol 9.08
    2-phenylethanol 20.41
    styrene 2.14
    dioctyl adipate 9.18
    dimethyl sulfate 16.16
    ethyl butyrate 16.96
    methyl lactate 32.0
    butyl lactate 20.71
    diethyl carbonate 11.62
    propanediol butyl ether 39.23
    triethyl orthoformate 15.1
    p-tert-butyltoluene 5.22
    methyl 4-tert-butylbenzoate 13.4
    morpholine 57.65
    tert-butylamine 21.92
    n-dodecanol 7.08
    dimethoxymethane 17.95
    ethylene carbonate 30.64
    cyrene 22.99
    2-ethoxyethyl acetate 12.96
    2-ethylhexyl acetate 13.97
    1,2,4-trichlorobenzene 14.43
    4-methylpyridine 16.55
    dibutyl ether 7.42
    2,6-dimethyl-4-heptanol 9.08
    DEF 20.06
    dimethyl isosorbide 33.15
    tetrachloroethylene 42.36
    eugenol 19.19
    triacetin 15.94
    span 80 37.16
    1,4-butanediol 47.27
    1,1-dichloroethane 15.43
    2-methyl-1-pentanol 11.02
    methyl formate 45.86
    2-methyl-1-butanol 35.84
    n-decane 1.75
    butyronitrile 20.07
    3,7-dimethyl-1-octanol 10.29
    1-chlorooctane 5.1
    1-chlorotetradecane 2.21
    n-nonane 1.82
    undecane 1.33
    tert-butylcyclohexane 1.34
    cyclooctane 1.43
    cyclopentanol 78.26
    tetrahydropyran 28.73
    tert-amyl methyl ether 7.78
    2,5,8-trioxanonane 34.06
    1-hexene 5.4
    2-isopropoxyethanol 19.52
    2,2,2-trifluoroethanol 133.11
    methyl butyrate 12.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction