Dimethyl Sulfone

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  • Identifiers

    CAS number
    67-71-0

    Molecular formula
    C2H6O2S

    SMILES
    CS(=O)(=O)C

  • Odor profile

    Fragrance
    Sulfurous 69.33%
    Onion 46.46%
    Garlic 45.64%
    Pungent 42.53%
    Alliaceous 42.41%
    Burnt 42.39%
    Roasted 40.2%
    Meaty 32.94%
    Cooked 31.93%
    Savory 31.91%

     

    Flavor
    Sulfurous 60.18%
    Sulfur 55.03%
    Burnt 40.06%
    Garlic 36.87%
    Mustard 33.66%
    Pungent 30.52%
    Bitter 29.52%
    Onion 24.21%
    Strong 23.77%
    Horseradish 23.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    7.42 (neutral)

    Molecular weight
    94.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • 109 °C

    Boiling point

    • 237.00 to 239.00 °C. @ 760.00 mm Hg

    Flash point

    • 93.52 ˚C est.

  • Synonyms

    • Dimethyl sulfone
    • Methyl sulfone
    • 67-71-0
    • Methylsulfonylmethane
    • DIMETHYLSULFONE
    • Dimethyl sulphone
    • Sulfonylbismethane
    • Methane, sulfonylbis-
    • sulfonyldimethane
    • (methylsulfonyl)methane
    • Methylsulfonyl methane
    • METHANESULFONYLMETHANE
    • Sulphonylbismethane
    • DMSO2
    • METHYL SULFONYL METHANE
    • NSC 63345
    • CCRIS 2938
    • methyl sulphone
    • Lignisul MSM
    • UNII-9H4PO4Z4FT
    • EINECS 200-665-9
    • Sulfonylbis-methane
    • 9H4PO4Z4FT
    • Opti MSM
    • Sulfone, dimethyl-
    • Methane, 1,1'-sulfonylbis-
    • DTXSID4043937
    • AI3-25306
    • METHOSULFONYLMETHANE
    • NSC-63345
    • CHEMBL25028
    • DIMETHYL SULFONE [MI]
    • CHEBI:9349
    • DTXCID2023937
    • DIMETHYL SULFONE [MART.]
    • NSC63345
    • METHYLSULFONYLMETHANE [VANDF]
    • METHYLSULFONYLMETHANE [USP-RS]
    • METHYLSULFONYLMETHANE [WHO-DD]
    • methylsulfone
    • MYTHYLSULFONYLMETHANE (MSM) [VANDF]
    • perdeuterodimethyl sulfone
    • methyl sulfonmethane
    • DIMETHYL SULFOXIDE IMPURITY A [EP IMPURITY]
    • DIMETHYL SULFONE (MART.)
    • METHYLSULFONYLMETHANE (USP-RS)
    • DIMETHYL SULFOXIDE IMPURITY A (EP IMPURITY)
    • MFCD00007566
    • dimethylsulfon
    • dimethylsulphone
    • methy sulfone
    • Sulphonyldimethane
    • methane, sulfonylbis
    • methylsulphonylmethane
    • MSM2000 Premium
    • (methanesulfonyl)methane
    • (methylsulphonyl)methane
    • 1,1'Sulfonylbismethane
    • Dimethyl sulfone, 98%
    • Methane, 1,1'sulfonylbis
    • MolMap_000019
    • Dimethyl sulfone (Standard)
    • DPHEAL SUL 16 HOT
    • SPECTRUM1505358
    • DIMETHYL SULFONE [INCI]
    • HY-Y1314R
    • MYTHYLSULFONYLMETHANE (MSM)
    • HY-Y1314
    • Tox21_303712
    • BDBM50026473
    • AKOS015897615
    • CCG-214558
    • DB14090
    • FM11048
    • CAS-67-71-0
    • NCGC00095990-01
    • NCGC00357027-01
    • DB-050533
    • CS-0017786
    • M0509
    • M1239
    • Methyl sulfonyl methane;MSM;Dimethyl sulfone
    • NS00006500
    • EN300-79559
    • D70240
    • A835859
    • Q423842
    • F0001-1776
    • Z417007936
    • Dimethyl sulfone, Standard for quantitative NMR, TraceCERT(R)
    • Methylsulfonylmethane, United States Pharmacopeia (USP) Reference Standard
    • Methylsulfonylmethane, Pharmaceutical Secondary Standard; Certified Reference Material
    • XZ5

  • Applications

    Dimethyl sulfone (CAS 67-71-0) is a polar sulfone commonly used as a solvent and processing aid across several sectors, with applications including as a humectant/conditioning agent in cosmetics and personal care; as a solvent or formulation component in household products; as an industrial-processing solvent and chemical intermediate in manufacturing; as a processing aid or stabilizer in polymers/plastics; as a solvent or additive in coatings and inks; and as a specialty solvent or electrolyte research material in electronics formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 150.38
    methanol 411.47
    isopropanol 84.6
    water 211.74
    ethyl acetate 84.98
    n-propanol 81.8
    acetone 256.43
    n-butanol 54.01
    acetonitrile 242.74
    DMF 477.13
    toluene 28.5
    isobutanol 50.19
    1,4-dioxane 162.95
    methyl acetate 132.24
    THF 163.31
    2-butanone 125.5
    n-pentanol 29.55
    sec-butanol 58.37
    n-hexane 14.52
    ethylene glycol 152.79
    NMP 318.48
    cyclohexane 25.19
    DMSO 266.25
    n-butyl acetate 33.94
    n-octanol 33.42
    chloroform 119.0
    n-propyl acetate 39.02
    acetic acid 186.25
    dichloromethane 107.42
    cyclohexanone 115.29
    propylene glycol 111.18
    isopropyl acetate 41.16
    DMAc 363.53
    2-ethoxyethanol 96.22
    isopentanol 32.19
    n-heptane 13.81
    ethyl formate 84.74
    1,2-dichloroethane 72.9
    n-hexanol 34.42
    2-methoxyethanol 250.03
    isobutyl acetate 23.13
    tetrachloromethane 31.1
    n-pentyl acetate 24.81
    transcutol 183.42
    n-heptanol 21.09
    ethylbenzene 16.23
    MIBK 36.85
    2-propoxyethanol 95.63
    tert-butanol 73.77
    MTBE 45.54
    2-butoxyethanol 46.93
    propionic acid 112.27
    o-xylene 29.85
    formic acid 230.6
    diethyl ether 80.27
    m-xylene 21.25
    p-xylene 23.73
    chlorobenzene 34.14
    dimethyl carbonate 77.3
    n-octane 5.99
    formamide 290.0
    cyclopentanone 159.91
    2-pentanone 76.33
    anisole 50.31
    cyclopentyl methyl ether 67.43
    gamma-butyrolactone 163.22
    1-methoxy-2-propanol 148.15
    pyridine 101.3
    3-pentanone 89.96
    furfural 174.81
    n-dodecane 5.48
    diethylene glycol 129.82
    diisopropyl ether 20.6
    tert-amyl alcohol 51.76
    acetylacetone 108.87
    n-hexadecane 5.72
    acetophenone 53.55
    methyl propionate 102.22
    isopentyl acetate 25.74
    trichloroethylene 105.65
    n-nonanol 29.47
    cyclohexanol 48.88
    benzyl alcohol 39.22
    2-ethylhexanol 21.33
    isooctanol 15.53
    dipropyl ether 39.01
    1,2-dichlorobenzene 36.08
    ethyl lactate 41.02
    propylene carbonate 74.48
    n-methylformamide 252.02
    2-pentanol 33.38
    n-pentane 16.42
    1-propoxy-2-propanol 61.74
    1-methoxy-2-propyl acetate 52.36
    2-(2-methoxypropoxy) propanol 67.37
    mesitylene 16.26
    ε-caprolactone 83.1
    p-cymene 16.25
    epichlorohydrin 111.59
    1,1,1-trichloroethane 61.2
    2-aminoethanol 136.57
    morpholine-4-carbaldehyde 275.5
    sulfolane 159.4
    2,2,4-trimethylpentane 5.85
    2-methyltetrahydrofuran 84.39
    n-hexyl acetate 41.41
    isooctane 3.89
    2-(2-butoxyethoxy)ethanol 78.01
    sec-butyl acetate 24.34
    tert-butyl acetate 39.76
    decalin 9.01
    glycerin 183.23
    diglyme 139.02
    acrylic acid 131.28
    isopropyl myristate 20.98
    n-butyric acid 70.57
    acetyl acetate 68.13
    di(2-ethylhexyl) phthalate 26.38
    ethyl propionate 49.88
    nitromethane 364.88
    1,2-diethoxyethane 48.23
    benzonitrile 50.23
    trioctyl phosphate 17.7
    1-bromopropane 39.49
    gamma-valerolactone 190.0
    n-decanol 22.93
    triethyl phosphate 25.74
    4-methyl-2-pentanol 16.81
    propionitrile 98.41
    vinylene carbonate 80.02
    1,1,2-trichlorotrifluoroethane 138.86
    DMS 58.02
    cumene 14.15
    2-octanol 15.86
    2-hexanone 44.66
    octyl acetate 29.45
    limonene 23.81
    1,2-dimethoxyethane 167.49
    ethyl orthosilicate 22.83
    tributyl phosphate 21.65
    diacetone alcohol 59.13
    N,N-dimethylaniline 44.7
    acrylonitrile 141.28
    aniline 52.49
    1,3-propanediol 110.37
    bromobenzene 26.75
    dibromomethane 69.99
    1,1,2,2-tetrachloroethane 93.99
    2-methyl-cyclohexyl acetate 30.49
    tetrabutyl urea 35.7
    diisobutyl methanol 14.72
    2-phenylethanol 37.17
    styrene 20.34
    dioctyl adipate 34.22
    dimethyl sulfate 108.5
    ethyl butyrate 33.0
    methyl lactate 92.32
    butyl lactate 29.8
    diethyl carbonate 29.12
    propanediol butyl ether 61.47
    triethyl orthoformate 27.85
    p-tert-butyltoluene 16.37
    methyl 4-tert-butylbenzoate 49.19
    morpholine 152.54
    tert-butylamine 48.65
    n-dodecanol 18.98
    dimethoxymethane 207.26
    ethylene carbonate 63.88
    cyrene 70.11
    2-ethoxyethyl acetate 42.18
    2-ethylhexyl acetate 22.37
    1,2,4-trichlorobenzene 45.82
    4-methylpyridine 82.47
    dibutyl ether 28.23
    2,6-dimethyl-4-heptanol 14.72
    DEF 122.99
    dimethyl isosorbide 92.21
    tetrachloroethylene 75.75
    eugenol 53.94
    triacetin 64.6
    span 80 57.88
    1,4-butanediol 44.65
    1,1-dichloroethane 69.53
    2-methyl-1-pentanol 20.72
    methyl formate 204.44
    2-methyl-1-butanol 36.08
    n-decane 8.45
    butyronitrile 62.89
    3,7-dimethyl-1-octanol 25.32
    1-chlorooctane 18.86
    1-chlorotetradecane 9.94
    n-nonane 8.48
    undecane 6.49
    tert-butylcyclohexane 7.35
    cyclooctane 8.84
    cyclopentanol 67.1
    tetrahydropyran 84.12
    tert-amyl methyl ether 38.91
    2,5,8-trioxanonane 119.29
    1-hexene 23.42
    2-isopropoxyethanol 51.57
    2,2,2-trifluoroethanol 132.06
    methyl butyrate 55.24

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction