Dimethyl methylphosphonate

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  • Identifiers

    CAS number
    756-79-6

    Molecular formula
    C3H9O3P

    SMILES
    COP(=O)(C)OC

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Ethereal 56.6%
    Fruity 52.97%
    Fresh 41.42%
    Sharp 31.17%
    Odorless 28.13%
    Winey 27.68%
    Pungent 27.41%
    Sweet 27.15%
    Rummy 26.42%
    Green 26.41%

     

    Flavor
    Fruity 57.32%
    Bitter 45.54%
    Sweet 39.54%
    Green 36.37%
    Sharp 30.14%
    Ether 28.53%
    Ethereal 27.31%
    Pungent 27.14%
    Tropical 25.21%
    Fruit 24.99%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    6.67 (neutral)

    Molecular weight
    124.08 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Melting point expt.

    • <50 °C

    Boiling point

    • 358 °F at 760 mmHg (NTP, 1992)
    • 181 °C; 79.5 °C at 20 mm Hg

    Flash point

    • 49.34 ˚C est.
    • 110 °F (NTP, 1992)

    Solubility expt.

    • greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
    • Miscible in alcohol, ether, benzene, acetone, carbon tetrachloride; insoluble in heavy mineral oil
    • Soluble in ethanol, ether
    • Miscible in water

  • Synonyms

    • DIMETHYL METHYLPHOSPHONATE
    • 756-79-6
    • DMMP
    • Pyrol dmmp
    • Fyrol DMMP
    • Dimethyl methanephosphonate
    • Dimethylmethylphosphonate
    • [methoxy(methyl)phosphoryl]oxymethane
    • Phosphonic acid, methyl-, dimethyl ester
    • Dimethoxymethylphosphine oxide
    • NCI-C54762
    • Methanephosphonic acid dimethyl ester
    • methylphosphonic acid dimethyl ester
    • CCRIS 876
    • o,o-Dimethyl methylphosphonate
    • NSC 62240
    • Metaran
    • Methyl phosphonic acid, dimethyl ester
    • HSDB 2590
    • Reoflam DMMP
    • EINECS 212-052-3
    • Dimethoxymethyl phosphine oxide
    • BRN 0878263
    • Phosphonic acid, methyl-,dimethyl ester
    • DTXSID0020494
    • AI3-08678
    • Furan tf 2000
    • UNII-20Z996230U
    • NSC-62240
    • Methanephosphonic acid, dimethyl ester
    • P-Methylphosphonic acid dimethyl ester
    • DTXCID40494
    • Phosphonic acid, P-methyl-, dimethyl ester
    • 20Z996230U
    • EC 212-052-3
    • 4-04-00-03499 (Beilstein Handbook Reference)
    • methyl-phosphonic acid dimethyl ester
    • Dimethyl ester of methylphosphonic acid
    • DIMETHYL METHYLPHOSPHONATE [HSDB]
    • CAS-756-79-6
    • dimethyl methyl phosphonate
    • MFCD00008349
    • dimethyl methylphosphonoate
    • dimethyl methyl-phosphonate
    • MeP(O)(OMe)2
    • DMMP [MI]
    • dimethyl methane phosphonate
    • NCIOpen2_003730
    • SCHEMBL35767
    • ghl.PD_Mitscher_leg0.664
    • H3C-PO(OCH3)2
    • WLN: 1OPO&1&O1
    • CHEMBL2924224
    • SCHEMBL11333660
    • Dimethyl methylphosphonate, 97%
    • (methoxy-methylphosphoryl)oxymethane
    • NSC62240
    • methane phosphonic acid dimethylester
    • Tox21_201534
    • Tox21_303029
    • methyl-phosphonic-acid dimethyl ester
    • methane phosphonic acid dimethyl ester
    • AKOS015913384
    • Phosphonic acid, methyl,dimethyl ester
    • FD74762
    • NCGC00249063-01
    • NCGC00256579-01
    • NCGC00259084-01
    • DB-055976
    • CS-0040741
    • M0943
    • NS00009428
    • A838480
    • Q417529
    • Dimethyl methylphosphonate, purum, >=97.0% (GC)
    • 212-052-3

  • Applications

    Dimethyl methylphosphonate (CAS 756-79-6) is used primarily as a solvent and reactive intermediate in organophosphorus chemistry, and as a precursor for phosphorus-containing flame retardants and plasticizers employed in polymers and coatings. It also functions as a processing aid and reagent in chemical manufacturing workflows. In chemical defense and security contexts, it is widely used as a surrogate or simulant for organophosphorus nerve agents to validate detection systems, decontamination procedures, and testing protocols. In research and industry, DMMP supports sensor development and analytical method validation for phosphorus-containing compounds, and may be evaluated for use in coatings, inks, and adhesives under controlled conditions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 759.66
    methanol 1618.19
    isopropanol 489.03
    water 1509.44
    ethyl acetate 110.48
    n-propanol 516.59
    acetone 229.76
    n-butanol 352.7
    acetonitrile 297.0
    DMF 646.21
    toluene 49.89
    isobutanol 311.75
    1,4-dioxane 302.4
    methyl acetate 181.0
    THF 370.59
    2-butanone 193.77
    n-pentanol 193.09
    sec-butanol 401.64
    n-hexane 33.14
    ethylene glycol 387.1
    NMP 501.99
    cyclohexane 50.11
    DMSO 507.04
    n-butyl acetate 34.69
    n-octanol 79.58
    chloroform 511.82
    n-propyl acetate 53.54
    acetic acid 561.16
    dichloromethane 526.92
    cyclohexanone 176.33
    propylene glycol 337.02
    isopropyl acetate 57.41
    DMAc 564.13
    2-ethoxyethanol 473.79
    isopentanol 194.89
    n-heptane 22.51
    ethyl formate 185.23
    1,2-dichloroethane 231.49
    n-hexanol 102.94
    2-methoxyethanol 920.21
    isobutyl acetate 29.23
    tetrachloromethane 141.31
    n-pentyl acetate 50.98
    transcutol 278.75
    n-heptanol 86.24
    ethylbenzene 25.13
    MIBK 54.32
    2-propoxyethanol 209.25
    tert-butanol 403.66
    MTBE 182.19
    2-butoxyethanol 157.81
    propionic acid 308.41
    o-xylene 50.6
    formic acid 1049.15
    diethyl ether 234.44
    m-xylene 31.35
    p-xylene 36.73
    chlorobenzene 67.42
    dimethyl carbonate 57.26
    n-octane 11.03
    formamide 1149.65
    cyclopentanone 225.32
    2-pentanone 118.63
    anisole 77.96
    cyclopentyl methyl ether 149.98
    gamma-butyrolactone 243.54
    1-methoxy-2-propanol 486.71
    pyridine 202.02
    3-pentanone 100.08
    furfural 300.77
    n-dodecane 6.69
    diethylene glycol 230.73
    diisopropyl ether 40.73
    tert-amyl alcohol 355.93
    acetylacetone 76.39
    n-hexadecane 7.03
    acetophenone 66.09
    methyl propionate 125.0
    isopentyl acetate 28.8
    trichloroethylene 317.51
    n-nonanol 68.78
    cyclohexanol 222.58
    benzyl alcohol 99.28
    2-ethylhexanol 49.0
    isooctanol 62.74
    dipropyl ether 57.1
    1,2-dichlorobenzene 70.02
    ethyl lactate 55.13
    propylene carbonate 100.33
    n-methylformamide 620.29
    2-pentanol 191.92
    n-pentane 53.89
    1-propoxy-2-propanol 115.86
    1-methoxy-2-propyl acetate 46.91
    2-(2-methoxypropoxy) propanol 92.48
    mesitylene 21.03
    ε-caprolactone 147.02
    p-cymene 20.32
    epichlorohydrin 320.8
    1,1,1-trichloroethane 152.77
    2-aminoethanol 632.98
    morpholine-4-carbaldehyde 405.29
    sulfolane 270.94
    2,2,4-trimethylpentane 20.25
    2-methyltetrahydrofuran 270.52
    n-hexyl acetate 59.31
    isooctane 9.46
    2-(2-butoxyethoxy)ethanol 128.33
    sec-butyl acetate 34.67
    tert-butyl acetate 52.39
    decalin 15.4
    glycerin 477.29
    diglyme 232.95
    acrylic acid 272.44
    isopropyl myristate 23.52
    n-butyric acid 241.63
    acetyl acetate 49.21
    di(2-ethylhexyl) phthalate 29.72
    ethyl propionate 52.51
    nitromethane 576.47
    1,2-diethoxyethane 76.35
    benzonitrile 73.9
    trioctyl phosphate 23.9
    1-bromopropane 161.51
    gamma-valerolactone 315.79
    n-decanol 46.03
    triethyl phosphate 29.15
    4-methyl-2-pentanol 77.76
    propionitrile 188.35
    vinylene carbonate 106.45
    1,1,2-trichlorotrifluoroethane 300.91
    DMS 34.2
    cumene 22.45
    2-octanol 58.78
    2-hexanone 67.04
    octyl acetate 33.41
    limonene 33.83
    1,2-dimethoxyethane 383.73
    ethyl orthosilicate 31.53
    tributyl phosphate 23.7
    diacetone alcohol 99.62
    N,N-dimethylaniline 72.63
    acrylonitrile 210.96
    aniline 138.69
    1,3-propanediol 562.97
    bromobenzene 51.44
    dibromomethane 320.05
    1,1,2,2-tetrachloroethane 291.85
    2-methyl-cyclohexyl acetate 38.17
    tetrabutyl urea 35.71
    diisobutyl methanol 29.97
    2-phenylethanol 61.26
    styrene 30.41
    dioctyl adipate 32.26
    dimethyl sulfate 94.37
    ethyl butyrate 35.2
    methyl lactate 117.86
    butyl lactate 51.31
    diethyl carbonate 26.41
    propanediol butyl ether 121.67
    triethyl orthoformate 36.33
    p-tert-butyltoluene 20.61
    methyl 4-tert-butylbenzoate 72.39
    morpholine 440.76
    tert-butylamine 288.77
    n-dodecanol 32.45
    dimethoxymethane 329.14
    ethylene carbonate 85.42
    cyrene 105.4
    2-ethoxyethyl acetate 64.09
    2-ethylhexyl acetate 24.38
    1,2,4-trichlorobenzene 82.42
    4-methylpyridine 169.18
    dibutyl ether 44.29
    2,6-dimethyl-4-heptanol 29.97
    DEF 199.96
    dimethyl isosorbide 108.4
    tetrachloroethylene 248.61
    eugenol 82.53
    triacetin 54.22
    span 80 75.31
    1,4-butanediol 227.47
    1,1-dichloroethane 219.46
    2-methyl-1-pentanol 131.68
    methyl formate 322.48
    2-methyl-1-butanol 229.27
    n-decane 12.8
    butyronitrile 173.83
    3,7-dimethyl-1-octanol 54.19
    1-chlorooctane 35.46
    1-chlorotetradecane 12.84
    n-nonane 12.89
    undecane 8.68
    tert-butylcyclohexane 14.53
    cyclooctane 18.44
    cyclopentanol 296.54
    tetrahydropyran 230.59
    tert-amyl methyl ether 147.31
    2,5,8-trioxanonane 152.83
    1-hexene 58.71
    2-isopropoxyethanol 214.89
    2,2,2-trifluoroethanol 345.32
    methyl butyrate 75.64

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction