Dimethipin

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  • Identifiers

    CAS number
    55290-64-7

    Molecular formula
    C6H10O4S2

    SMILES
    CC1=C(S(=O)(=O)CCS1(=O)=O)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 66.27%
    Burnt 31.37%
    Roasted 30.41%
    Sulfurous 22.87%
    Caramellic 22.12%
    Cooked 21.4%
    Savory 20.38%
    Pungent 18.16%
    Nutty 16.32%
    Meaty 16.02%

     

    Flavor
    Bitter 51.64%
    Nutty 27.86%
    Sulfur 22.66%
    Taco 22.21%
    Roasted peanuts 21.14%
    Bread crust 20.7%
    Nitrile 20.47%
    Very strong 19.48%
    Roasted 19.4%
    Fenugreek 19.4%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.5

    pKa est.
    8.85 (weak base)

    Molecular weight
    210.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    439°C

    Melting point expt.

    • 167 to 169 °C

    Flash point

    • 216.63 ˚C est.

    Solubility expt.

    • In acetonitrile 180 g/l, methanol 10.7 g/l, toluene 8.979 g/l (all at 25 °C).
    • In water, 4.6 g/l at 25 °C.

  • Synonyms

    • DIMETHIPIN
    • 55290-64-7
    • Harvade
    • Oxidimethiin
    • Tetrathiin
    • Tetrathiin (desiccant)
    • Caswell No. 472AA
    • Harvade-5F
    • 5,6-Dimethyl-2,3-dihydro-1,4-dithiine 1,1,4,4-tetraoxide
    • Dimethipin [ISO]
    • Dimethipin [ANSI:BSI:ISO]
    • UNI-N252
    • HSDB 6615
    • UBI-N 252
    • UNII-HLV651AHBB
    • HLV651AHBB
    • N 252
    • EINECS 259-572-7
    • EPA Pesticide Chemical Code 118901
    • DTXSID0024052
    • 2,3-Dihydro-5,6-dimethyl-1,4-dithiin 1,1,4,4-tetraoxide
    • 2,3-Dihydro-5,6-dimethyl-1,4-dithiine 1,1,4,4-tetraoxide
    • DIMETHIPIN [HSDB]
    • DTXCID704052
    • UBI-N252
    • 2,3-Dihydro-5,6-dimethyl-1,4-dithiin-1,1,4,4-tetraoxide
    • CHEBI:81912
    • 1,4-Dithiin, 2,3-dihydro-5,6-dimethyl-, 1,1,4,4-tetraoxide
    • p-Dithiane, 2,3-dehydro-2,3-dimethyl-, tetroxide
    • Oxydimethiin
    • Dimethipin (ANSI:BSI:ISO)
    • 2,3-Dihydro-5,6-dimethyl-1,4-dithiin 1,1,4,4-tetroxide
    • CAS-55290-64-7
    • Harvade-5F (9CI)
    • Harvade5F
    • Dimethipin 100 microg/mL in Methanol
    • Harvade5F (9CI)
    • OXIDIMETHIIN [MI]
    • UNIN252
    • SCHEMBL119508
    • UBIN 252
    • CHEMBL3183474
    • Tox21_201644
    • Tox21_300423
    • CCG-15173
    • STK833417
    • AKOS000583006
    • NCGC00160477-01
    • NCGC00160477-02
    • NCGC00160477-03
    • NCGC00254274-01
    • NCGC00259193-01
    • DB-052712
    • NS00002214
    • C18719
    • AH-034/32860053
    • SR-01000390589
    • 2,3Dihydro5,6dimethyl1,4dithiin1,1,4,4tetraoxide
    • Q3028191
    • SR-01000390589-1
    • 2,3Dihydro5,6dimethyl1,4dithiine 1,1,4,4tetraoxide
    • 1,4Dithiin, 2,3dihydro5,6dimethyl, 1,1,4,4tetraoxide
    • 5,6-Dimethyl-2,3-dihydro-1,4-dithiine 1,1,4,4-tetraoxide #
    • 2,3,-DIHYDRO-5,6-DIMETHYL-1,4-DITHIIN 1,1,4,4-TETRAOXIDE
    • 5,6-Dimethyl-2,3-dihydro-1lambda~6~,4lambda~6~-dithiine-1,1,4,4-tetrone

  • Applications

    Dimethipin, CAS 55290-64-7, is used primarily in agriculture as a nematicide and insecticide to control soil-dwelling and plant pests; it is commonly the active ingredient in registered pesticide formulations and may be applied as a soil drench, seed treatment, or foliar application depending on the product label; it is involved in formulation and manufacturing of pesticide products; its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.37
    methanol 14.03
    isopropanol 3.73
    water 3.67
    ethyl acetate 34.89
    n-propanol 3.3
    acetone 79.12
    n-butanol 2.43
    acetonitrile 57.7
    DMF 254.12
    toluene 3.85
    isobutanol 2.02
    1,4-dioxane 82.41
    methyl acetate 53.61
    THF 72.12
    2-butanone 39.88
    n-pentanol 2.13
    sec-butanol 3.26
    n-hexane 0.39
    ethylene glycol 5.69
    NMP 240.05
    cyclohexane 1.35
    DMSO 190.8
    n-butyl acetate 16.55
    n-octanol 3.84
    chloroform 28.72
    n-propyl acetate 16.71
    acetic acid 22.93
    dichloromethane 37.07
    cyclohexanone 59.51
    propylene glycol 3.07
    isopropyl acetate 21.09
    DMAc 184.53
    2-ethoxyethanol 21.18
    isopentanol 2.01
    n-heptane 0.67
    ethyl formate 33.12
    1,2-dichloroethane 26.13
    n-hexanol 2.8
    2-methoxyethanol 45.87
    isobutyl acetate 6.26
    tetrachloromethane 5.61
    n-pentyl acetate 11.6
    transcutol 61.54
    n-heptanol 2.71
    ethylbenzene 3.4
    MIBK 12.66
    2-propoxyethanol 17.83
    tert-butanol 5.82
    MTBE 7.92
    2-butoxyethanol 10.16
    propionic acid 11.26
    o-xylene 6.22
    formic acid 30.45
    diethyl ether 13.65
    m-xylene 3.61
    p-xylene 5.9
    chlorobenzene 11.75
    dimethyl carbonate 38.5
    n-octane 0.48
    formamide 113.73
    cyclopentanone 107.35
    2-pentanone 23.67
    anisole 23.04
    cyclopentyl methyl ether 19.01
    gamma-butyrolactone 146.43
    1-methoxy-2-propanol 23.64
    pyridine 39.1
    3-pentanone 28.58
    furfural 184.47
    n-dodecane 0.45
    diethylene glycol 25.13
    diisopropyl ether 4.5
    tert-amyl alcohol 4.99
    acetylacetone 95.33
    n-hexadecane 0.54
    acetophenone 37.64
    methyl propionate 34.41
    isopentyl acetate 12.93
    trichloroethylene 58.33
    n-nonanol 4.13
    cyclohexanol 4.64
    benzyl alcohol 9.95
    2-ethylhexanol 2.65
    isooctanol 2.31
    dipropyl ether 7.32
    1,2-dichlorobenzene 20.9
    ethyl lactate 12.01
    propylene carbonate 62.68
    n-methylformamide 82.84
    2-pentanol 2.07
    n-pentane 0.38
    1-propoxy-2-propanol 12.65
    1-methoxy-2-propyl acetate 34.33
    2-(2-methoxypropoxy) propanol 24.84
    mesitylene 3.33
    ε-caprolactone 49.87
    p-cymene 3.93
    epichlorohydrin 85.54
    1,1,1-trichloroethane 21.89
    2-aminoethanol 5.93
    morpholine-4-carbaldehyde 220.72
    sulfolane 185.15
    2,2,4-trimethylpentane 0.32
    2-methyltetrahydrofuran 32.7
    n-hexyl acetate 15.53
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 22.92
    sec-butyl acetate 10.29
    tert-butyl acetate 24.46
    decalin 0.87
    glycerin 11.29
    diglyme 79.62
    acrylic acid 16.57
    isopropyl myristate 8.38
    n-butyric acid 10.09
    acetyl acetate 50.87
    di(2-ethylhexyl) phthalate 8.21
    ethyl propionate 19.63
    nitromethane 240.48
    1,2-diethoxyethane 23.54
    benzonitrile 22.15
    trioctyl phosphate 5.41
    1-bromopropane 5.41
    gamma-valerolactone 187.2
    n-decanol 3.15
    triethyl phosphate 17.23
    4-methyl-2-pentanol 1.62
    propionitrile 15.17
    vinylene carbonate 61.67
    1,1,2-trichlorotrifluoroethane 61.37
    DMS 37.62
    cumene 2.92
    2-octanol 2.45
    2-hexanone 15.25
    octyl acetate 9.6
    limonene 5.83
    1,2-dimethoxyethane 80.03
    ethyl orthosilicate 12.7
    tributyl phosphate 8.59
    diacetone alcohol 21.99
    N,N-dimethylaniline 16.34
    acrylonitrile 33.75
    aniline 9.04
    1,3-propanediol 7.62
    bromobenzene 10.27
    dibromomethane 15.85
    1,1,2,2-tetrachloroethane 39.83
    2-methyl-cyclohexyl acetate 16.4
    tetrabutyl urea 15.43
    diisobutyl methanol 2.87
    2-phenylethanol 9.61
    styrene 4.58
    dioctyl adipate 15.29
    dimethyl sulfate 106.48
    ethyl butyrate 19.17
    methyl lactate 23.62
    butyl lactate 9.51
    diethyl carbonate 18.62
    propanediol butyl ether 9.09
    triethyl orthoformate 15.78
    p-tert-butyltoluene 3.92
    methyl 4-tert-butylbenzoate 27.15
    morpholine 50.12
    tert-butylamine 3.24
    n-dodecanol 2.49
    dimethoxymethane 88.43
    ethylene carbonate 42.68
    cyrene 40.43
    2-ethoxyethyl acetate 28.94
    2-ethylhexyl acetate 11.19
    1,2,4-trichlorobenzene 25.09
    4-methylpyridine 32.48
    dibutyl ether 6.8
    2,6-dimethyl-4-heptanol 2.87
    DEF 53.29
    dimethyl isosorbide 75.24
    tetrachloroethylene 29.3
    eugenol 23.41
    triacetin 36.49
    span 80 13.25
    1,4-butanediol 3.37
    1,1-dichloroethane 15.79
    2-methyl-1-pentanol 2.06
    methyl formate 92.97
    2-methyl-1-butanol 1.97
    n-decane 0.76
    butyronitrile 10.51
    3,7-dimethyl-1-octanol 3.87
    1-chlorooctane 2.89
    1-chlorotetradecane 1.49
    n-nonane 0.65
    undecane 0.57
    tert-butylcyclohexane 0.58
    cyclooctane 0.52
    cyclopentanol 7.75
    tetrahydropyran 19.67
    tert-amyl methyl ether 7.32
    2,5,8-trioxanonane 61.89
    1-hexene 1.23
    2-isopropoxyethanol 11.18
    2,2,2-trifluoroethanol 34.11
    methyl butyrate 25.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction