Diisopropanolamine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    110-97-4

    Molecular formula
    C6H15NO2

    SMILES
    CC(CNCC(C)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 55.86%
    Odorless 41.49%
    Sweet 25.01%
    Savory 21.88%
    Alcoholic 21.55%
    Cheesy 21.07%
    Ripe 19.38%
    Meaty 18.02%
    Oily 17.87%
    Animal 13.5%

     

    Flavor
    Odorless 50.05%
    Mild 28.91%
    Sulfurous 28.04%
    Onion 24.3%
    Sweet-like 23.65%
    Fishy 23.38%
    Very slight 21.79%
    Yeasty 20.88%
    Meat broth 19.9%
    Catty 19.82%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.8

    pKa est.
    7.67 (neutral)

    Molecular weight
    133.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 107.6 °F (NTP, 1992)
    • 32-42 °C
    • 42 °C

    Boiling point

    • 480.2 °F at 760 mmHg (NTP, 1992)
    • 249 °C
    • 248 °C

    Flash point

    • 130.76 ˚C est.
    • 259 °F (NTP, 1992)
    • 255 °F (127 °C) (open cup)
    • 127 °C o.c.

    Solubility expt.

    • Soluble (>=10 mg/ml) (NTP, 1992)
    • Miscible in alcohol. Slightly soluble in toluene. Insoluble in hydrocarbons.
    • In water, 8.6X10+5 mg/L at 25 °C
    • Solubility in water, g/100ml at 20 °C: 87

  • Synonyms

    • DIISOPROPANOLAMINE
    • 110-97-4
    • Bis(2-hydroxypropyl)amine
    • 1,1'-Iminodipropan-2-ol
    • Bis(2-propanol)amine
    • 1,1'-Iminodi-2-propanol
    • 2-Propanol, 1,1'-iminobis-
    • Di-2-propanolamine
    • di-isopropanolamine
    • DIPA (alcohol)
    • 1-[(2-hydroxypropyl)amino]propan-2-ol
    • Dipropyl-2,2'-dihydroxy-amine
    • N,N-Bis(2-hydroxypropyl)amine
    • 1-(2-hydroxypropylamino)propan-2-ol
    • 1,1'-Iminobis-2-propanol
    • 2-Propanol, 1,1'-iminodi-
    • NSC 4963
    • 2-Propanol,1,1'-iminobis-
    • CCRIS 6234
    • HSDB 338
    • Diisopropanolamine [NF]
    • diisopropanolamin
    • DIPA alcohol
    • NSC-4963
    • EINECS 203-820-9
    • 1,1'-Iminobis[2-propanol]
    • BRN 0605363
    • 0W44HYL8T5
    • DTXSID8020179
    • di(2-hydroxypropyl)amine
    • DTXCID20179
    • DIISOPROPANOLAMINE [II]
    • DIISOPROPANOLAMINE [MI]
    • 1,1'-azanediylbis propan-2-ol
    • DIISOPROPANOLAMINE [HSDB]
    • 1,1'-azanediyldi(propan-2-ol)
    • CHEBI:143266
    • DIISOPROPANOLAMINE [VANDF]
    • DIISOPROPANOLAMINE [MART.]
    • EC 203-820-9
    • 3-04-00-00761 (Beilstein Handbook Reference)
    • 1,1'-IMINOBIS(2-PROPANOL)
    • Diisopropanolamine (NF)
    • 1335-54-2
    • DIISOPROPANOLAMINE (II)
    • DIISOPROPANOLAMINE (MART.)
    • 1,1'-Azanediylbis(propan-2-ol)
    • 1-((2-hydroxypropyl)amino)propan-2-ol
    • 203-820-9
    • CAS-110-97-4
    • DI-ISOPROPANOL AMINE
    • UNII-0W44HYL8T5
    • Di2propanolamine
    • diiso-propanolamine
    • diisopropanol amine
    • 1,1'-IMINODI-2-PROPANOL(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
    • 1,1'-IMINODI-2-PROPANOL[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
    • BIS(2-HYDROXYPROPYL)AMINE(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
    • BIS(2-HYDROXYPROPYL)AMINE[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
    • BIS(2-PROPANOL)AMINE(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
    • BIS(2-PROPANOL)AMINE[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
    • Bis(2propanol)amine
    • MFCD00004531
    • 1,1'Iminodi2propanol
    • 1,1'Iminodipropan2ol
    • 1,1'Iminobis2propanol
    • Bis(2-propanol) amine
    • Bis(2hydroxypropyl)amine
    • 2-Propanol,1'-iminodi-
    • 2Propanol, 1,1'iminodi
    • 1,1'-Imino-2-propanol
    • 2-Propanol,1'-iminobis-
    • 2Propanol, 1,1'iminobis
    • Dipropyl2,2'dihydroxyamine
    • bis-(2-hydroxypropyl)amine
    • N,NBis(2hydroxypropyl)amine
    • bis-(2-hydroxypropyl)-amine
    • SCHEMBL22774
    • Di(2-hydroxy-n-propyl) amine
    • 1,1'-Imino-di(2-propanol)
    • CHEMBL2106303
    • DIISOPROPANOLAMINE [INCI]
    • NSC4963
    • WLN: QY1 & 1M1YQ1
    • 2,2'-DIHYDROXYDIPROPYLAMINE
    • Tox21_201602
    • Tox21_302859
    • BBL013266
    • STK503623
    • AKOS005457854
    • DIPA low freeze grade 85 (Salt/Mix)
    • DIPA low freeze grade 90 (Salt/Mix)
    • NCGC00249081-01
    • NCGC00256476-01
    • NCGC00259151-01
    • VS-03726
    • Diisopropanolamine(DL- and meso- mixture)
    • Bis(2-hydroxypropyl)amine, >=98.0% (T)
    • D0924
    • NS00001427
    • EN300-722418
    • Q777543
    • F0001-0230
    • 9AFD2C98-2177-4499-8EB2-1C8EA079F21D

  • Applications

    Diisopropanolamine (CAS 110-97-4) is used primarily as a solvent and processing aid in coatings, inks, and adhesives; serves as a reactive intermediate for the synthesis of surfactants and polymer additives; acts as a neutralizing/pH-adjusting agent for waterborne polymers (such as polyurethane dispersions and acrylics) to improve emulsification and dispersion; is employed in formulations for specialized cleaners and detergents; and is used as an ingredient in metalworking fluids as a corrosion-inhibiting and surface-enhancing additive; may be used as an intermediate in other chemical production.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 202.3
    methanol 558.14
    isopropanol 69.0
    water 777.83
    ethyl acetate 7.55
    n-propanol 125.8
    acetone 14.23
    n-butanol 79.31
    acetonitrile 14.96
    DMF 123.86
    toluene 1.26
    isobutanol 54.19
    1,4-dioxane 48.82
    methyl acetate 8.87
    THF 85.6
    2-butanone 9.91
    n-pentanol 30.8
    sec-butanol 48.21
    n-hexane 2.14
    ethylene glycol 360.86
    NMP 202.83
    cyclohexane 4.98
    DMSO 158.79
    n-butyl acetate 10.36
    n-octanol 16.3
    chloroform 14.32
    n-propyl acetate 7.59
    acetic acid 456.81
    dichloromethane 13.95
    cyclohexanone 43.34
    propylene glycol 275.18
    isopropyl acetate 4.44
    DMAc 84.39
    2-ethoxyethanol 88.35
    isopentanol 28.05
    n-heptane 4.19
    ethyl formate 23.85
    1,2-dichloroethane 7.34
    n-hexanol 38.77
    2-methoxyethanol 220.77
    isobutyl acetate 5.58
    tetrachloromethane 5.03
    n-pentyl acetate 8.15
    transcutol 101.92
    n-heptanol 23.32
    ethylbenzene 1.26
    MIBK 3.64
    2-propoxyethanol 88.84
    tert-butanol 41.35
    MTBE 6.45
    2-butoxyethanol 54.31
    propionic acid 152.84
    o-xylene 2.35
    formic acid 656.3
    diethyl ether 6.76
    m-xylene 1.64
    p-xylene 2.09
    chlorobenzene 3.22
    dimethyl carbonate 5.95
    n-octane 1.43
    formamide 287.36
    cyclopentanone 60.08
    2-pentanone 6.83
    anisole 4.37
    cyclopentyl methyl ether 21.24
    gamma-butyrolactone 101.03
    1-methoxy-2-propanol 89.46
    pyridine 18.02
    3-pentanone 6.2
    furfural 87.62
    n-dodecane 0.96
    diethylene glycol 132.7
    diisopropyl ether 1.97
    tert-amyl alcohol 33.95
    acetylacetone 8.36
    n-hexadecane 0.99
    acetophenone 7.56
    methyl propionate 11.42
    isopentyl acetate 8.58
    trichloroethylene 12.64
    n-nonanol 14.06
    cyclohexanol 59.39
    benzyl alcohol 14.99
    2-ethylhexanol 15.97
    isooctanol 14.79
    dipropyl ether 11.39
    1,2-dichlorobenzene 4.26
    ethyl lactate 19.93
    propylene carbonate 42.06
    n-methylformamide 132.36
    2-pentanol 22.19
    n-pentane 2.65
    1-propoxy-2-propanol 51.41
    1-methoxy-2-propyl acetate 13.75
    2-(2-methoxypropoxy) propanol 35.21
    mesitylene 1.69
    ε-caprolactone 50.45
    p-cymene 3.28
    epichlorohydrin 38.63
    1,1,1-trichloroethane 3.57
    2-aminoethanol 370.35
    morpholine-4-carbaldehyde 144.49
    sulfolane 159.08
    2,2,4-trimethylpentane 1.42
    2-methyltetrahydrofuran 35.04
    n-hexyl acetate 12.13
    isooctane 0.79
    2-(2-butoxyethoxy)ethanol 54.25
    sec-butyl acetate 4.09
    tert-butyl acetate 4.88
    decalin 1.54
    glycerin 422.33
    diglyme 67.01
    acrylic acid 188.1
    isopropyl myristate 4.91
    n-butyric acid 101.88
    acetyl acetate 6.95
    di(2-ethylhexyl) phthalate 13.33
    ethyl propionate 6.85
    nitromethane 117.28
    1,2-diethoxyethane 11.03
    benzonitrile 8.66
    trioctyl phosphate 10.52
    1-bromopropane 4.13
    gamma-valerolactone 105.68
    n-decanol 9.98
    triethyl phosphate 9.89
    4-methyl-2-pentanol 8.45
    propionitrile 13.21
    vinylene carbonate 37.39
    1,1,2-trichlorotrifluoroethane 120.3
    DMS 9.83
    cumene 1.85
    2-octanol 9.81
    2-hexanone 5.97
    octyl acetate 8.36
    limonene 5.74
    1,2-dimethoxyethane 50.38
    ethyl orthosilicate 9.77
    tributyl phosphate 11.01
    diacetone alcohol 17.45
    N,N-dimethylaniline 6.15
    acrylonitrile 21.06
    aniline 10.84
    1,3-propanediol 266.31
    bromobenzene 1.84
    dibromomethane 8.21
    1,1,2,2-tetrachloroethane 13.98
    2-methyl-cyclohexyl acetate 13.45
    tetrabutyl urea 15.16
    diisobutyl methanol 7.58
    2-phenylethanol 14.8
    styrene 1.33
    dioctyl adipate 11.46
    dimethyl sulfate 16.31
    ethyl butyrate 9.76
    methyl lactate 34.16
    butyl lactate 22.31
    diethyl carbonate 7.07
    propanediol butyl ether 64.88
    triethyl orthoformate 12.12
    p-tert-butyltoluene 3.54
    methyl 4-tert-butylbenzoate 17.56
    morpholine 86.01
    tert-butylamine 19.39
    n-dodecanol 7.55
    dimethoxymethane 26.8
    ethylene carbonate 30.69
    cyrene 58.08
    2-ethoxyethyl acetate 10.56
    2-ethylhexyl acetate 7.18
    1,2,4-trichlorobenzene 6.24
    4-methylpyridine 9.63
    dibutyl ether 6.38
    2,6-dimethyl-4-heptanol 7.58
    DEF 25.61
    dimethyl isosorbide 52.75
    tetrachloroethylene 14.55
    eugenol 26.9
    triacetin 17.9
    span 80 52.01
    1,4-butanediol 105.21
    1,1-dichloroethane 3.52
    2-methyl-1-pentanol 16.13
    methyl formate 62.77
    2-methyl-1-butanol 37.09
    n-decane 1.51
    butyronitrile 13.27
    3,7-dimethyl-1-octanol 10.79
    1-chlorooctane 3.5
    1-chlorotetradecane 1.72
    n-nonane 1.54
    undecane 1.15
    tert-butylcyclohexane 1.4
    cyclooctane 1.79
    cyclopentanol 101.7
    tetrahydropyran 30.29
    tert-amyl methyl ether 7.21
    2,5,8-trioxanonane 58.0
    1-hexene 3.29
    2-isopropoxyethanol 38.2
    2,2,2-trifluoroethanol 161.53
    methyl butyrate 11.72

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction