Dihydrolanosterol

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  • Identifiers

    CAS number
    79-62-9

    Molecular formula
    C30H52O

    SMILES
    C[C@H](CCCC(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 89.12%
    Amber 53.61%
    Sandalwood 50.32%
    Dry 49.36%
    Cedar 38.56%
    Vetiver 38.5%
    Balsamic 37.32%
    Waxy 36.59%
    Spicy 34.23%
    Musk 33.93%

     

    Flavor
    Woody 63.12%
    Pine 35.69%
    Wood 34.91%
    Camphor 33.92%
    Balsam 30.87%
    Spice 28.81%
    Sweet 28.09%
    Dry 27.83%
    Fir needle 25.76%
    Balsamic 23.86%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.4

    pKa est.
    8.12 (weak base)

    Molecular weight
    428.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    507°C

    Flash point

    • 212.7 ˚C est.

  • Synonyms

    • Dihydrolanosterol
    • 79-62-9
    • Lanostenol
    • 24,25-Dihydrolanosterol
    • Dihydrolanosterin
    • 5alpha-Lanost-8-en-3beta-ol
    • 9H273A8B2X
    • DTXSID101000181
    • CHEBI:28113
    • (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
    • (3 beta)-lanost-8-en-3-ol
    • (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((2R)-6-methylheptan-2-yl)-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta(a)phenanthren-3-ol
    • RefChem:89799
    • Lanost-8-en-3-ol, (3beta)-
    • DTXCID801427148
    • Lanost-8-en-3beta-ol
    • 24-dihydrolanosterol
    • Lanosterol, dihydro-
    • Lanost-8-en-3-ol, (3.beta.)-
    • Lanost-8-en-3.beta.-ol
    • (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
    • Lanostenol;Dihydrolanosterin
    • 3beta-Hydroxylanost-8-ene
    • UNII-9H273A8B2X
    • (3beta)-Lanost-8-en-3-ol
    • 5alpha-Lanost-8-en-3 beta-ol
    • Lanost-8-en-3-ol
    • Lanost-8-en-3-ol #
    • SCHEMBL288306
    • orb1297011
    • CHEMBL4213010
    • GLXC-24027
    • LMST01010087
    • AKOS040763665
    • EBC-617390
    • FD65406
    • (1R,3aR,5aR,7S,9aS,11aR)-3a,6,6,9a,11a-pentamethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol
    • (3S,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
    • DA-62882
    • MS-27601
    • 5.ALPHA.-LANOST-8-EN-3.BETA.-OL
    • HY-122410
    • CS-0085117
    • 4,4,14a-trimethyl-5a-cholesta-8-en-3b-ol
    • C05109
    • G12566
    • 4,4,14alpha-trimethyl-5alpha-cholesta-8-en-3beta-ol
    • Q27103510
    • 4,4,14.ALPHA.-TRIMETHYL-5.ALPHA.-CHOLEST-8-EN-3.BETA.-OL
    • (3S,5R,10S,13R,14R,17R)-17-[(1R)-1,5-dimethylhexyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
    • 79-62-9

  • Applications

    Dihydrolanosterol (CAS 79-62-9) is used as an intermediate in pharmaceutical and fine-chemical manufacturing for the synthesis of steroidal compounds; in biochemical research it serves as a sterol substrate and analytical standard for lipid and sterol metabolism studies; in cosmetics and personal care it can be used as a sterol-based starting material for formulation components; and as a specialty chemical, it is employed to prepare other sterol derivatives and related compounds for various specialty applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.93
    methanol 2.94
    isopropanol 10.36
    water 0.05
    ethyl acetate 18.58
    n-propanol 16.1
    acetone 18.86
    n-butanol 19.86
    acetonitrile 3.56
    DMF 23.09
    toluene 36.31
    isobutanol 13.61
    1,4-dioxane 42.45
    methyl acetate 10.99
    THF 82.08
    2-butanone 20.39
    n-pentanol 13.21
    sec-butanol 7.85
    n-hexane 1.98
    ethylene glycol 0.64
    NMP 38.23
    cyclohexane 2.54
    DMSO 7.41
    n-butyl acetate 26.81
    n-octanol 11.72
    chloroform 47.16
    n-propyl acetate 16.27
    acetic acid 7.61
    dichloromethane 26.77
    cyclohexanone 42.34
    propylene glycol 1.61
    isopropyl acetate 26.05
    DMAc 38.85
    2-ethoxyethanol 18.03
    isopentanol 20.55
    n-heptane 2.51
    ethyl formate 5.69
    1,2-dichloroethane 17.81
    n-hexanol 18.74
    2-methoxyethanol 18.38
    isobutyl acetate 21.18
    tetrachloromethane 11.09
    n-pentyl acetate 35.53
    transcutol 83.53
    n-heptanol 19.81
    ethylbenzene 15.15
    MIBK 28.21
    2-propoxyethanol 49.01
    tert-butanol 11.17
    MTBE 18.28
    2-butoxyethanol 46.26
    propionic acid 7.55
    o-xylene 19.56
    formic acid 1.62
    diethyl ether 22.82
    m-xylene 28.54
    p-xylene 17.64
    chlorobenzene 27.96
    dimethyl carbonate 10.48
    n-octane 0.82
    formamide 2.54
    cyclopentanone 44.99
    2-pentanone 25.96
    anisole 32.77
    cyclopentyl methyl ether 37.67
    gamma-butyrolactone 34.13
    1-methoxy-2-propanol 27.36
    pyridine 39.62
    3-pentanone 20.65
    furfural 29.4
    n-dodecane 0.4
    diethylene glycol 14.39
    diisopropyl ether 11.87
    tert-amyl alcohol 8.47
    acetylacetone 33.24
    n-hexadecane 0.5
    acetophenone 27.86
    methyl propionate 17.77
    isopentyl acetate 38.07
    trichloroethylene 42.15
    n-nonanol 14.6
    cyclohexanol 13.93
    benzyl alcohol 18.73
    2-ethylhexanol 15.91
    isooctanol 19.17
    dipropyl ether 25.92
    1,2-dichlorobenzene 27.39
    ethyl lactate 9.11
    propylene carbonate 19.54
    n-methylformamide 6.05
    2-pentanol 12.37
    n-pentane 2.25
    1-propoxy-2-propanol 42.27
    1-methoxy-2-propyl acetate 51.35
    2-(2-methoxypropoxy) propanol 35.35
    mesitylene 16.86
    ε-caprolactone 39.05
    p-cymene 15.5
    epichlorohydrin 39.1
    1,1,1-trichloroethane 24.2
    2-aminoethanol 3.24
    morpholine-4-carbaldehyde 48.4
    sulfolane 31.56
    2,2,4-trimethylpentane 1.73
    2-methyltetrahydrofuran 34.07
    n-hexyl acetate 34.32
    isooctane 1.95
    2-(2-butoxyethoxy)ethanol 47.45
    sec-butyl acetate 17.55
    tert-butyl acetate 36.05
    decalin 2.42
    glycerin 3.31
    diglyme 85.02
    acrylic acid 5.73
    isopropyl myristate 14.06
    n-butyric acid 18.89
    acetyl acetate 17.01
    di(2-ethylhexyl) phthalate 18.66
    ethyl propionate 16.54
    nitromethane 10.77
    1,2-diethoxyethane 34.5
    benzonitrile 16.4
    trioctyl phosphate 12.23
    1-bromopropane 14.08
    gamma-valerolactone 72.47
    n-decanol 8.82
    triethyl phosphate 15.46
    4-methyl-2-pentanol 12.98
    propionitrile 8.47
    vinylene carbonate 19.66
    1,1,2-trichlorotrifluoroethane 22.46
    DMS 21.9
    cumene 12.01
    2-octanol 10.87
    2-hexanone 19.7
    octyl acetate 16.19
    limonene 15.88
    1,2-dimethoxyethane 36.52
    ethyl orthosilicate 18.63
    tributyl phosphate 11.55
    diacetone alcohol 28.7
    N,N-dimethylaniline 26.84
    acrylonitrile 7.73
    aniline 24.65
    1,3-propanediol 8.99
    bromobenzene 33.3
    dibromomethane 19.51
    1,1,2,2-tetrachloroethane 35.02
    2-methyl-cyclohexyl acetate 28.45
    tetrabutyl urea 17.86
    diisobutyl methanol 12.85
    2-phenylethanol 30.99
    styrene 16.73
    dioctyl adipate 21.65
    dimethyl sulfate 15.06
    ethyl butyrate 23.07
    methyl lactate 9.3
    butyl lactate 26.4
    diethyl carbonate 14.51
    propanediol butyl ether 23.55
    triethyl orthoformate 27.36
    p-tert-butyltoluene 16.12
    methyl 4-tert-butylbenzoate 48.55
    morpholine 44.83
    tert-butylamine 8.85
    n-dodecanol 5.36
    dimethoxymethane 35.68
    ethylene carbonate 16.63
    cyrene 29.99
    2-ethoxyethyl acetate 48.82
    2-ethylhexyl acetate 31.94
    1,2,4-trichlorobenzene 34.95
    4-methylpyridine 39.37
    dibutyl ether 13.32
    2,6-dimethyl-4-heptanol 12.85
    DEF 25.08
    dimethyl isosorbide 65.64
    tetrachloroethylene 24.64
    eugenol 43.13
    triacetin 35.68
    span 80 29.79
    1,4-butanediol 3.46
    1,1-dichloroethane 17.56
    2-methyl-1-pentanol 14.32
    methyl formate 4.37
    2-methyl-1-butanol 16.29
    n-decane 1.21
    butyronitrile 11.47
    3,7-dimethyl-1-octanol 13.5
    1-chlorooctane 6.91
    1-chlorotetradecane 1.75
    n-nonane 0.99
    undecane 0.64
    tert-butylcyclohexane 2.57
    cyclooctane 1.4
    cyclopentanol 11.75
    tetrahydropyran 39.59
    tert-amyl methyl ether 14.69
    2,5,8-trioxanonane 50.95
    1-hexene 6.8
    2-isopropoxyethanol 18.56
    2,2,2-trifluoroethanol 4.2
    methyl butyrate 17.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction