Dihydrochalcone

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  • Identifiers

    CAS number
    1083-30-3

    Molecular formula
    C15H14O

    SMILES
    C1=CC=C(C=C1)CCC(=O)C2=CC=CC=C2

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Balsamic 70.27%
    Floral 69.85%
    Sweet 48.77%
    Rose 48.43%
    Herbal 43.61%
    Honey 43.33%
    Spicy 42.34%
    Fruity 37.63%
    Powdery 31.31%
    Cinnamon 28.31%

     

    Flavor
    Balsam 66.68%
    Rose 48.71%
    Honey 43.17%
    Sweet 38.76%
    Floral 35.69%
    Balsamic 32.54%
    Peach 30.75%
    Apricot 28.85%
    Chocolate 26.86%
    Hyacinth 25.52%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    7.09 (neutral)

    Molecular weight
    210.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    336°C

    Melting point expt.

    • 72 - 73 °C

    Flash point

    • 153.29 ˚C est.

  • Synonyms

    • 1,3-diphenylpropan-1-one
    • Dihydrochalcone
    • 1083-30-3
    • 3-Phenylpropiophenone
    • beta-Phenylpropiophenone
    • 1,3-Diphenyl-1-propanone
    • Hydrochalcone
    • Benzylacetophenone
    • Hydrocinnamophenone
    • 1,3-Diphenyl-1-oxopropane
    • 1-Propanone, 1,3-diphenyl-
    • Phenethyl phenyl ketone
    • Phenyl phenethyl ketone
    • 2-Phenethyl phenyl ketone
    • 1,3-Diphenyl-3-propanone
    • .omega.-Benzyl acetophenone
    • BENZYL ACETOPHENONE
    • Propiophenone, 3-phenyl-
    • .beta.-Phenylpropiophenone
    • omega-Benzyl acetophenone
    • 1,3-diphenyl-propan-1-one
    • CHEBI:71231
    • UNII-H5W525SX7Q
    • NSC 12245
    • w-Benzylacetophenone
    • H5W525SX7Q
    • 3-Phenyl propiophenone
    • 3-Phenyl-Propiophenone
    • MFCD00039563
    • NSC-12245
    • 1, 3-Diphenyl-3-propanone
    • AI3-22096
    • CHEMBL490512
    • DTXSID7061481
    • NSC12245
    • 3-?Phenylpropiophenone
    • Benzylacetophenon
    • ?-Phenylpropiophenone
    • |A-Phenylpropiophenone
    • beta-phenyl propiophenone
    • 1-Benzoyl-2-phenylethane
    • 1-Propanone,3-diphenyl-
    • ChemDiv2_000107
    • b-PHENYLPROPIOPHENONE
    • 1,3 diphenylpropan-1-one
    • SCHEMBL30572
    • 1-Propanone,1,3-diphenyl-
    • DTXCID7033109
    • HMS1369E19
    • Laquo omegaraquo-benzyl acetophenone
    • AC9766
    • BDBM50479153
    • laquo Omegaraquo -benzyl acetophenone
    • LMPK12120464
    • AKOS001586597
    • GS-3688
    • SY045967
    • DB-040822
    • CS-0063340
    • D5479
    • EU-0066881
    • EN300-102554
    • A801855
    • SR-01000390066
    • Q2357209
    • SR-01000390066-1
    • Z385416922
    • 621-467-2

  • Applications

    Dihydrochalcone (CAS 1083-30-3) is primarily used as a fragrance-building block and aroma ingredient in perfumery and cosmetics, contributing a mild sweet, vanilla-like note and functioning as a component in formulation. It also serves as an intermediate in industrial organic synthesis, enabling the preparation of more complex chalcone derivatives for flavor and fragrance chemistry. The compound may be evaluated for use as a fragrance additive in household cleaning products. In pharmaceutical and medicinal chemistry contexts, it can act as a synthetic intermediate for chalcone-based scaffolds in research. Applications are typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 41.58
    methanol 55.99
    isopropanol 21.17
    water 0.25
    ethyl acetate 276.09
    n-propanol 35.77
    acetone 166.68
    n-butanol 34.24
    acetonitrile 175.0
    DMF 384.07
    toluene 76.61
    isobutanol 21.76
    1,4-dioxane 409.28
    methyl acetate 223.56
    THF 308.72
    2-butanone 198.18
    n-pentanol 34.73
    sec-butanol 23.82
    n-hexane 7.52
    ethylene glycol 16.59
    NMP 189.84
    cyclohexane 8.06
    DMSO 277.13
    n-butyl acetate 187.75
    n-octanol 20.9
    chloroform 750.63
    n-propyl acetate 184.27
    acetic acid 124.52
    dichloromethane 831.36
    cyclohexanone 295.79
    propylene glycol 19.68
    isopropyl acetate 161.4
    DMAc 437.56
    2-ethoxyethanol 103.84
    isopentanol 41.71
    n-heptane 6.96
    ethyl formate 120.57
    1,2-dichloroethane 719.6
    n-hexanol 45.06
    2-methoxyethanol 140.23
    isobutyl acetate 122.73
    tetrachloromethane 36.12
    n-pentyl acetate 84.31
    transcutol 1202.57
    n-heptanol 23.66
    ethylbenzene 83.28
    MIBK 120.63
    2-propoxyethanol 122.3
    tert-butanol 39.58
    MTBE 78.22
    2-butoxyethanol 77.27
    propionic acid 99.14
    o-xylene 58.65
    formic acid 38.27
    diethyl ether 132.47
    m-xylene 53.61
    p-xylene 80.45
    chlorobenzene 208.13
    dimethyl carbonate 157.86
    n-octane 3.15
    formamide 126.12
    cyclopentanone 322.04
    2-pentanone 159.67
    anisole 263.48
    cyclopentyl methyl ether 102.16
    gamma-butyrolactone 405.27
    1-methoxy-2-propanol 101.95
    pyridine 394.32
    3-pentanone 160.33
    furfural 426.25
    n-dodecane 3.07
    diethylene glycol 89.65
    diisopropyl ether 40.51
    tert-amyl alcohol 38.34
    acetylacetone 342.1
    n-hexadecane 3.75
    acetophenone 228.88
    methyl propionate 205.72
    isopentyl acetate 175.46
    trichloroethylene 1216.67
    n-nonanol 23.38
    cyclohexanol 34.28
    benzyl alcohol 97.86
    2-ethylhexanol 42.88
    isooctanol 25.63
    dipropyl ether 99.48
    1,2-dichlorobenzene 242.82
    ethyl lactate 72.1
    propylene carbonate 245.43
    n-methylformamide 144.31
    2-pentanol 23.79
    n-pentane 3.05
    1-propoxy-2-propanol 93.15
    1-methoxy-2-propyl acetate 209.93
    2-(2-methoxypropoxy) propanol 140.13
    mesitylene 41.05
    ε-caprolactone 248.11
    p-cymene 42.11
    epichlorohydrin 629.4
    1,1,1-trichloroethane 326.49
    2-aminoethanol 32.74
    morpholine-4-carbaldehyde 331.09
    sulfolane 376.76
    2,2,4-trimethylpentane 4.69
    2-methyltetrahydrofuran 145.21
    n-hexyl acetate 110.65
    isooctane 4.18
    2-(2-butoxyethoxy)ethanol 193.28
    sec-butyl acetate 134.05
    tert-butyl acetate 165.38
    decalin 13.7
    glycerin 41.48
    diglyme 517.41
    acrylic acid 105.72
    isopropyl myristate 53.93
    n-butyric acid 132.82
    acetyl acetate 230.58
    di(2-ethylhexyl) phthalate 49.82
    ethyl propionate 191.26
    nitromethane 476.08
    1,2-diethoxyethane 330.02
    benzonitrile 175.15
    trioctyl phosphate 28.17
    1-bromopropane 160.34
    gamma-valerolactone 444.09
    n-decanol 18.78
    triethyl phosphate 86.94
    4-methyl-2-pentanol 26.61
    propionitrile 131.41
    vinylene carbonate 271.54
    1,1,2-trichlorotrifluoroethane 292.35
    DMS 202.88
    cumene 53.82
    2-octanol 14.96
    2-hexanone 158.4
    octyl acetate 57.06
    limonene 51.08
    1,2-dimethoxyethane 331.64
    ethyl orthosilicate 79.48
    tributyl phosphate 46.41
    diacetone alcohol 133.69
    N,N-dimethylaniline 132.92
    acrylonitrile 237.03
    aniline 93.95
    1,3-propanediol 49.02
    bromobenzene 227.35
    dibromomethane 405.79
    1,1,2,2-tetrachloroethane 847.04
    2-methyl-cyclohexyl acetate 118.47
    tetrabutyl urea 61.76
    diisobutyl methanol 36.29
    2-phenylethanol 90.68
    styrene 121.66
    dioctyl adipate 97.97
    dimethyl sulfate 224.12
    ethyl butyrate 180.45
    methyl lactate 83.07
    butyl lactate 71.18
    diethyl carbonate 141.31
    propanediol butyl ether 64.69
    triethyl orthoformate 119.3
    p-tert-butyltoluene 38.96
    methyl 4-tert-butylbenzoate 137.17
    morpholine 279.28
    tert-butylamine 25.65
    n-dodecanol 16.24
    dimethoxymethane 265.8
    ethylene carbonate 208.64
    cyrene 113.09
    2-ethoxyethyl acetate 178.36
    2-ethylhexyl acetate 137.96
    1,2,4-trichlorobenzene 272.33
    4-methylpyridine 250.95
    dibutyl ether 86.08
    2,6-dimethyl-4-heptanol 36.29
    DEF 234.62
    dimethyl isosorbide 272.76
    tetrachloroethylene 432.51
    eugenol 133.27
    triacetin 184.35
    span 80 84.67
    1,4-butanediol 20.94
    1,1-dichloroethane 321.94
    2-methyl-1-pentanol 46.84
    methyl formate 137.4
    2-methyl-1-butanol 33.5
    n-decane 4.77
    butyronitrile 104.06
    3,7-dimethyl-1-octanol 37.49
    1-chlorooctane 28.96
    1-chlorotetradecane 13.54
    n-nonane 4.03
    undecane 3.76
    tert-butylcyclohexane 12.77
    cyclooctane 3.58
    cyclopentanol 29.19
    tetrahydropyran 185.24
    tert-amyl methyl ether 64.96
    2,5,8-trioxanonane 307.2
    1-hexene 38.55
    2-isopropoxyethanol 80.03
    2,2,2-trifluoroethanol 58.39
    methyl butyrate 231.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction